Inhibition of ATP citrate lyase induces triglyceride accumulation with altered fatty acid composition in cancer cells

Inhibition of ATP Citrate Lyase Induces an Anticancer Effect via Reactive Oxygen Species

(2013) Toshiro Migita et al.   AMERICAN JOURNAL OF PATHOLOGY

Proteomic and Lipidomic Signatures of Lipid Metabolism in NASH-Associated Hepatocellular Carcinoma

(2013) K. Muir et al.   CANCER RESEARCH

ATP-Citrate Lyase: A Key Player in Cancer Metabolism

(2012) N. Zaidi et al.   CANCER RESEARCH

Elovl6 promotes nonalcoholic steatohepatitis

(2012) Takashi Matsuzaka et al.   HEPATOLOGY

ATP Citrate Lyase Knockdown Induces Growth Arrest and Apoptosis through Different Cell- and Environment-Dependent Mechanisms

(2012) N. Zaidi et al.   MOLECULAR CANCER THERAPEUTICS

ATP Citrate Lyase Inhibitors as Novel Cancer Therapeutic Agents

(2012) Xu-Yu Zu et al.   Recent Patents on Anti-Cancer Drug Discovery

Is fat so bad? Modulation of endoplasmic reticulum stress by lipid droplet formation

(2011) Ivan Hapala et al.   BIOLOGY OF THE CELL

Carnitine palmitoyltransferase 1C promotes cell survival and tumor growth under conditions of metabolic stress

(2011) K. Zaugg et al.   GENES & DEVELOPMENT

The Lipogenesis Pathway as a Cancer Target

(2011) Hanley N. Abramson   JOURNAL OF MEDICINAL CHEMISTRY

Soraphen A, an inhibitor of acetyl CoA carboxylase activity, interferes with fatty acid elongation

(2010) Donald B. Jump et al.   BIOCHEMICAL PHARMACOLOGY

De novo Lipogenesis Protects Cancer Cells from Free Radicals and Chemotherapeutics by Promoting Membrane Lipid Saturation

(2010) E. Rysman et al.   CANCER RESEARCH

Increase of oxidant-related triglycerides and phosphatidylcholines in serum and small intestinal mucosa during development of intestinal polyp formation in Min mice

(2010) Kazutaka Ikeda et al.   CANCER SCIENCE

ATP-Citrate Lyase Reduction Mediates Palmitate-induced Apoptosis in Pancreatic Beta Cells

(2010) Kwan Yi Chu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Deficiency in hepatic ATP-citrate lyase affects VLDL-triglyceride mobilization and liver fatty acid composition in mice

(2010) Qiong Wang et al.   JOURNAL OF LIPID RESEARCH

Role of fatty acid elongases in determination of de novo synthesized monounsaturated fatty acid species

(2010) Christopher D. Green et al.   JOURNAL OF LIPID RESEARCH

A combination of alpha lipoic acid and calcium hydroxycitrate is efficient against mouse cancer models: Preliminary results

(2010) Schwartz   ONCOLOGY REPORTS

De novo fatty-acid synthesis and related pathways as molecular targets for cancer therapy

(2009) T Mashima et al.   BRITISH JOURNAL OF CANCER

Novel Lipogenic Enzyme ELOVL7 Is Involved in Prostate Cancer Growth through Saturated Long-Chain Fatty Acid Metabolism

(2009) K. Tamura et al.   CANCER RESEARCH

Elovl6: a new player in fatty acid metabolism and insulin sensitivity

(2009) Takashi Matsuzaka et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Fatty Acid Synthase: A Metabolic Enzyme and Candidate Oncogene in Prostate Cancer

(2009) Toshiro Migita et al.   JNCI-Journal of the National Cancer Institute

The key roles of elongases and desaturases in mammalian fatty acid metabolism: Insights from transgenic mice

(2009) Hervé Guillou et al.   PROGRESS IN LIPID RESEARCH

ATP-Citrate Lyase Links Cellular Metabolism to Histone Acetylation

(2009) K. E. Wellen et al.   SCIENCE

ATP Citrate Lyase: Activation and Therapeutic Implications in Non-Small Cell Lung Cancer

(2008) T. Migita et al.   CANCER RESEARCH

Abrogation of hepatic ATP-citrate lyase protects against fatty liver and ameliorates hyperglycemia in leptin receptor-deficient mice

(2008) Qiong Wang et al.   HEPATOLOGY

Overexpression of fatty acid synthase is associated with palmitoylation of Wnt1 and cytoplasmic stabilization of β-catenin in prostate cancer

(2008) Michelangelo Fiorentino et al.   LABORATORY INVESTIGATION