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Title
The Role of the Immune System in Triplet Repeat Expansion Diseases
Authors
Keywords
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Journal
MEDIATORS OF INFLAMMATION
Volume 2015, Issue -, Pages 1-11
Publisher
Hindawi Limited
Online
2015-03-23
DOI
10.1155/2015/873860
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- Mutant Huntingtin promotes autonomous microglia activation via myeloid lineage-determining factors
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- Huntington disease: natural history, biomarkers and prospects for therapeutics
- (2014) Christopher A. Ross et al. Nature Reviews Neurology
- Blood expression profiles of fragile X premutation carriers identify candidate genes involved in neurodegenerative and infertility phenotypes
- (2014) Elisabet Mateu-Huertas et al. NEUROBIOLOGY OF DISEASE
- RAN translation and frameshifting as translational challenges at simple repeats of human neurodegenerative disorders
- (2014) Marzena Wojciechowska et al. NUCLEIC ACIDS RESEARCH
- Oligonucleotide-based strategies to combat polyglutamine diseases
- (2014) A. Fiszer et al. NUCLEIC ACIDS RESEARCH
- Immune Dysregulation as a Cause of Autoinflammation in Fragile X Premutation Carriers: Link between FMRI CGG Repeat Number and Decreased Cytokine Responses
- (2014) Milo Careaga et al. PLoS One
- Roles of the nucleolus in the CAG RNA-mediated toxicity
- (2013) Ho Tsoi et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- The Role of the Immune System in Huntington’s Disease
- (2013) Gisa Ellrichmann et al. Clinical & Developmental Immunology
- Distinct roles for Toll and autophagy pathways in double-stranded RNA toxicity in a Drosophila model of expanded repeat neurodegenerative diseases
- (2013) Saumya E. Samaraweera et al. HUMAN MOLECULAR GENETICS
- A critical role of astrocyte-mediated nuclear factor-κB-dependent inflammation in Huntington's disease
- (2013) Han-Yun Hsiao et al. HUMAN MOLECULAR GENETICS
- Inflammation in neurodegenerative diseases - an update
- (2013) Sandra Amor et al. IMMUNOLOGY
- Recent Advances in RNA Interference Therapeutics for CNS Diseases
- (2013) Pavitra S. Ramachandran et al. Neurotherapeutics
- Clinical features, neurogenetics and neuropathology of the polyglutamine spinocerebellar ataxias type 1, 2, 3, 6 and 7
- (2013) Udo Rüb et al. PROGRESS IN NEUROBIOLOGY
- Autophagy and apoptosis dysfunction in neurodegenerative disorders
- (2013) Saeid Ghavami et al. PROGRESS IN NEUROBIOLOGY
- Mechanisms of RNA-induced toxicity in CAG repeat disorders
- (2013) R Nalavade et al. Cell Death & Disease
- Depletion of Cognate Charged Transfer RNA Causes Translational Frameshifting within the Expanded CAG Stretch in Huntingtin
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- (2013) Robert I. Richards et al. Frontiers in Molecular Neuroscience
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- (2012) Paulina Galka-Marciniak et al. BIOLOGICAL CHEMISTRY
- An evaluation of oligonucleotide-based therapeutic strategies for polyQ diseases
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- (2012) Shawn J. Stochmanski et al. HUMAN MOLECULAR GENETICS
- PAMPs and DAMPs: signal 0s that spur autophagy and immunity
- (2012) Daolin Tang et al. IMMUNOLOGICAL REVIEWS
- Mutant huntingtin impairs immune cell migration in Huntington disease
- (2012) Wanda Kwan et al. JOURNAL OF CLINICAL INVESTIGATION
- Mutant huntingtin fragmentation in immune cells tracks Huntington’s disease progression
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- Automated Behavioral Phenotyping Reveals Presymptomatic Alterations in a SCA3 Genetrap Mouse Model
- (2012) Jeannette Hübener et al. Journal of Genetics and Genomics
- Carriers of the fragile X mental retardation 1 (FMR1) premutation allele present with increased levels of cytokine IL-10
- (2012) Diana Marek et al. Journal of Neuroinflammation
- Bone Marrow Transplantation Confers Modest Benefits in Mouse Models of Huntington's Disease
- (2012) W. Kwan et al. JOURNAL OF NEUROSCIENCE
- Cannabinoid Receptor 2 Signaling in Peripheral Immune Cells Modulates Disease Onset and Severity in Mouse Models of Huntington's Disease
- (2012) J. Bouchard et al. JOURNAL OF NEUROSCIENCE
- Mouse Models of Polyglutamine Diseases in Therapeutic Approaches: Review and Data Table. Part II
- (2012) Pawel M. Switonski et al. MOLECULAR NEUROBIOLOGY
- CAG expansion induces nucleolar stress in polyglutamine diseases
- (2012) H. Tsoi et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- RNAimmuno: A database of the nonspecific immunological effects of RNA interference and microRNA reagents
- (2012) M. Olejniczak et al. RNA
- Kynurenine 3-Monooxygenase Inhibition in Blood Ameliorates Neurodegeneration
- (2011) Daniel Zwilling et al. CELL
- Recent Advances in Understanding of the Immunological Off-Target Effects of siRNA
- (2011) Marta Olejniczak et al. CURRENT GENE THERAPY
- Genes and pathways affected by CAG-repeat RNA-based toxicity in Drosophila
- (2011) Shin-Yi Shieh et al. HUMAN MOLECULAR GENETICS
- Activation of the innate immune response and interferon signalling in myotonic dystrophy type 1 and type 2 cataracts
- (2011) Jeremy D. Rhodes et al. HUMAN MOLECULAR GENETICS
- Double-stranded RNA is pathogenic in Drosophila models of expanded repeat neurodegenerative diseases
- (2011) Kynan T. Lawlor et al. HUMAN MOLECULAR GENETICS
- Rational Design of Therapeutic siRNAs: Minimizing Off-targeting Potential to Improve the Safety of RNAi Therapy for Huntington's Disease
- (2011) Ryan L Boudreau et al. MOLECULAR THERAPY
- Preclinical Safety of RNAi-Mediated HTT Suppression in the Rhesus Macaque as a Potential Therapy for Huntington's Disease
- (2011) Jodi L McBride et al. MOLECULAR THERAPY
- Triplet repeat RNA structure and its role as pathogenic agent and therapeutic target
- (2011) W. J. Krzyzosiak et al. NUCLEIC ACIDS RESEARCH
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- (2011) Ren-Jun Hsu et al. PLoS One
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- (2010) Christopher J. Yuskaitis et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
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- (2010) Claudia Huichalaf et al. FASEB JOURNAL
- p53 activation mediates polyglutamine-expanded ataxin-3 upregulation of Bax expression in cerebellar and pontine nuclei neurons
- (2010) An-Hsun Chou et al. NEUROCHEMISTRY INTERNATIONAL
- Comprehensive Behavioral Testing in the R6/2 Mouse Model of Huntington's Disease Shows No Benefit from CoQ10 or Minocycline
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- Huntington's disease: The current state of research with peripheral tissues
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- (2009) J. E. Young et al. JOURNAL OF NEUROSCIENCE
- Neuroinflammation in Parkinson's disease: a target for neuroprotection?
- (2009) Etienne C Hirsch et al. LANCET NEUROLOGY
- Expression of mutant huntingtin in mouse brain astrocytes causes age-dependent neurological symptoms
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- Evidence of apoptosis and mitochondrial abnormalities in peripheral blood cells of Huntington’s disease patients
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- (2008) Libin Zhang et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- A novel pathogenic pathway of immune activation detectable before clinical onset in Huntington's disease
- (2008) Maria Björkqvist et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Induction of chemokines, MCP-1, and KC in the mutant huntingtin expressing neuronal cells because of proteasomal dysfunction
- (2008) Swetha K. Godavarthi et al. JOURNAL OF NEUROCHEMISTRY
- Inhibitors of Cytochrome c Release with Therapeutic Potential for Huntington's Disease
- (2008) X. Wang et al. JOURNAL OF NEUROSCIENCE
- The Inflammatory Response in Alzheimer's Disease
- (2008) Joseph Rogers JOURNAL OF PERIODONTOLOGY
- RNA toxicity is a component of ataxin-3 degeneration in Drosophila
- (2008) Ling-Bo Li et al. NATURE
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