Monophosphoryl lipid A inhibits the cytokine response of endothelial cells challenged with LPS

Inhibition of endocytosis exacerbates TNF-α-induced endothelial dysfunction via enhanced JNK and p38 activation

(2014) Hyehun Choi et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

MPLA inhibits release of cytotoxic mediators from human neutrophils while preserving efficient bacterial killing

(2014) Marie- Hélène Ruchaud-Sparagano et al.   IMMUNOLOGY AND CELL BIOLOGY

The attenuated inflammation of MPL is due to the lack of CD14-dependent tight dimerization of the TLR4/MD2 complex at the plasma membrane

(2014) Natsuko Tanimura et al.   INTERNATIONAL IMMUNOLOGY

The Immunobiology of Toll-Like Receptor 4 Agonists

(2013) Julia K. Bohannon et al.   SHOCK

Toll-like receptor 4 is involved in bacterial endotoxin-induced endothelial cell injury and SOC-mediated calcium regulation

(2012) Rongju Sun et al.   CELL BIOLOGY INTERNATIONAL

Atorvastatin suppresses LPS-induced rapid upregulation of Toll-like receptor 4 and its signaling pathway in endothelial cells

(2011) Ying Wang et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

CD14 Controls the LPS-Induced Endocytosis of Toll-like Receptor 4

(2011) Ivan Zanoni et al.   CELL

The Toll-Like Receptor 4 Agonist Monophosphoryl Lipid A Augments Innate Host Resistance to Systemic Bacterial Infection

(2011) Christopher D. Romero et al.   INFECTION AND IMMUNITY

MyD88-Dependent SHIP1 Regulates Proinflammatory Signaling Pathways in Dendritic Cells after Monophosphoryl Lipid A Stimulation of TLR4

(2011) Caglar Cekic et al.   JOURNAL OF IMMUNOLOGY

TLR4 Activation Induces Nontolerant Inflammatory Response in Endothelial Cells

(2010) Wenmeng Wang et al.   INFLAMMATION

Lipopolysaccharide-binding protein-mediated Toll-like receptor 4 dimerization enables rapid signal transduction against lipopolysaccharide stimulation on membrane-associated CD14-expressing cells

(2010) H. Tsukamoto et al.   INTERNATIONAL IMMUNOLOGY

Geniposide inhibits interleukin-6 and interleukin-8 production in lipopolysaccharide-induced human umbilical vein endothelial cells by blocking p38 and ERK1/2 signaling pathways

(2009) Hong-Tao Liu et al.   INFLAMMATION RESEARCH

Potent Phagocytic Activity with Impaired Antigen Presentation Identifying Lipopolysaccharide-Tolerant Human Monocytes: Demonstration in Isolated Monocytes from Cystic Fibrosis Patients

(2009) Carlos del Fresno et al.   JOURNAL OF IMMUNOLOGY

TRAM couples endocytosis of Toll-like receptor 4 to the induction of interferon-β

(2008) Jonathan C Kagan et al.   NATURE IMMUNOLOGY