Article
Dentistry, Oral Surgery & Medicine
Vrisiis Kofina, Mutlu Demirer, Barbaros S. Erdal, Timothy D. Eubank, Vedat O. Yildiz, Dimitris N. Tatakis, Binnaz Leblebicioglu
Summary: This study found that a history of bone grafting alters the healing response of soft tissues following implant placement surgery. Soft tissue closure was slower in grafted bone (GG) areas, and blood perfusion recovery was slower in GG sites.
JOURNAL OF PERIODONTOLOGY
(2021)
Review
Cell & Tissue Engineering
Qianli Ma, Zahra Miri, Havard Jostein Haugen, Amirhossein Moghanian, Dagnjia Loca
Summary: In 1892, J.L. Wolff proposed that bone could respond to mechanical and biophysical stimuli as a dynamic organ, providing an opportunity for investigations on bone and its potential for tissue repair. Mechanical stimulation through activities like exercise or machinery application can affect the differentiation and development of mesenchymal tissue. The review aims to clarify the extent to which mechanical stimulation can aid in bone tissue repair and regeneration, the underlying mechanisms, and the importance of vascularization in nutrient supply for bone healing and regeneration.
JOURNAL OF TISSUE ENGINEERING
(2023)
Article
Biochemistry & Molecular Biology
Annica Proehl, Milijana Batinic, Said Alkildani, Michael Hahn, Milena Radenkovic, Stevo Najman, Ole Jung, Mike Barbeck
Summary: The study showed that the new hyaluronate containing bone substitute material has comparable bone healing capacity to the control xenogeneic BSM, with no significant differences in bone formation or inflammatory tissue responses. Both materials were fully biocompatible and allowed for gradual osteoconductive bone regeneration without differences in tissue reactions compared to a sham operation group.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2021)
Article
Endocrinology & Metabolism
Deepak Kumar Khajuria, Vengadeshprabhu Karuppagounder, Irena Nowak, Diana E. Sepulveda, Gregory S. Lewis, Christopher C. Norbury, Wesley M. Raup-Konsavage, Kent E. Vrana, Fadia Kamal, Reyad A. Elbarbary
Summary: Bone fractures are common musculoskeletal injuries that require effective pain management. This study found that both cannabidiol (CBD) and cannabigerol (CBG) have potent analgesic effects and promote bone healing in a mouse model for tibial fracture. Therefore, CBD and CBG have the potential to be alternative therapeutic agents for managing postfracture pain.
JOURNAL OF BONE AND MINERAL RESEARCH
(2023)
Article
Endocrinology & Metabolism
Melanie Haffner-Luntzer, Deniz Ragipoglu, Mubashir Ahmad, Astrid Schoppa, Lena Steppe, Verena Fischer, Julia Luther, Timur Yorgan, Ernesto Bockamp, Michael Amling, Thorsten Schinke, Anita Ignatius
Summary: Despite improvements in fracture care, a percentage of fractures still heal poorly. The study investigated the potential of Wnt1 as a molecule to improve bone fracture healing. The results showed that Wnt1 promotes bone formation during fracture healing through YAP/BMP signaling. This suggests that Wnt1 could be used as a therapeutic agent for orthopedic complications.
JOURNAL OF BONE AND MINERAL RESEARCH
(2023)
Article
Dentistry, Oral Surgery & Medicine
Stefan Krennmair, Lukas Postl, Uwe Yacine Schwarze, Michael Malek, Michal Stimmelmayr, Gerald Krennmair
Summary: This study compared new bone formation, graft stability, and clinical implant outcome between maxillary sinus grafting using DPBM and DBBM. The results showed that both materials had similar effects on new bone formation and graft stability, with good implant retention.
CLINICAL ORAL IMPLANTS RESEARCH
(2023)
Article
Engineering, Biomedical
Lena Batoon, Susan M. Millard, Liza J. Raggatt, Cheyenne Sandrock, Edmund Pickering, Kyle Williams, Lucas W. H. Sun, Andy C. Wu, Katharine M. Irvine, Peter Pivonka, Vaida Glatt, Martin E. Wullschleger, David A. Hume, Allison R. Pettit
Summary: Research using mouse models investigated the bone regenerative potential of CSF1-Fc in healthy and osteoporotic fractures, revealing an effective treatment regimen that improves fracture union and strength.
Review
Biochemistry & Molecular Biology
Laura Caliogna, Marta Medetti, Valentina Bina, Alice Maria Brancato, Alberto Castelli, Eugenio Jannelli, Alessandro Ivone, Giulia Gastaldi, Salvatore Annunziata, Mario Mosconi, Gianluigi Pasta
Summary: This article reviews the signaling pathways modulated by PEMFs and their clinical applications, based on studies from PubMed and Embase. While identifying cell membrane receptors and pathways involved in bone healing, further research and clinical trials are needed to understand the dose-response relationship and practical applications of PEMFs.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2021)
Article
Immunology
Michael C. Tanner, Raban Arved Heller, Andreas Grimm, Stefan Zimmermann, Maximilian Pilz, Louisa Jurytko, Matthias Miska, Lars Helbig, Gerhard Schmidmaier, Patrick Haubruck
Summary: The study revealed a 9.04% incidence of occult infections in patients undergoing autologous bone grafting, impacting bone healing time and radiological outcomes to a non-significant extent. Factors such as diabetes, age, smoking, and higher BMI were found to have a significant negative influence on the outcome of bone grafting. Surgeons should be aware of the common occurrence of occult infections in treating recalcitrant non-unions and should pay special attention to high-risk patients.
JOURNAL OF INFLAMMATION RESEARCH
(2021)
Article
Orthopedics
Nima Anaraki, Amir Hossein Beyraghi, Abbas Raisi, Farshid Davoodi, Ghasem Farjanikish, Amin Bigham Sadegh
Summary: Treatment with Prunus dulcis extract at a dosage of 300 mg/kg accelerated tibial bone healing process in rabbits, reducing blood phosphorus levels and increasing blood calcium levels. In the treatment groups, antioxidant levels increased, serum MDA levels decreased, and radiographic scores and histopathological results showed faster healing effects.
JOURNAL OF ORTHOPAEDIC SURGERY AND RESEARCH
(2021)
Article
Chemistry, Multidisciplinary
Baixue Xiao, Yuxuan Liu, Indika Chandrasiri, Emmanuela Adjei-Sowah, Jared Mereness, Ming Yan, Danielle S. W. Benoit
Summary: This study developed a bone-targeted nanoparticle drug delivery system that enhances fracture healing by modulating macrophage polarization. The experimental results showed that the system is predominantly uptaken by fracture-associated macrophages, resulting in increased M2/M1 ratio and expedited fracture healing, accompanied by upregulation of anti-inflammatory genes and downregulation of pro-inflammatory genes.
Review
Nanoscience & Nanotechnology
Mingran Zhang, Jiaxue Liu, Tongtong Zhu, Hanxiang Le, Xukai Wang, Jinshan Guo, Guangyao Liu, Jianxun Ding
Summary: Bone adhesives are expected to have significant advantages in treating bone injuries compared to traditional internal fixation devices. Different research directions of bone adhesives, such as liquid scaffold and liquid plate, are summarized. Recent advances in mechanical strength, osseointegration, osteoconductivity, and osteoinductivity of bone adhesives are discussed.
ACS APPLIED MATERIALS & INTERFACES
(2022)
Review
Biochemistry & Molecular Biology
Micaela Berni, Alice Maria Brancato, Camilla Torriani, Valentina Bina, Salvatore Annunziata, Elena Cornella, Michelangelo Trucchi, Eugenio Jannelli, Mario Mosconi, Giulia Gastaldi, Laura Caliogna, Federico Alberto Grassi, Gianluigi Pasta
Summary: Low-level laser therapy (LLLT) is increasingly used in orthopedics practices to promote angiogenesis, fracture healing, and osteogenic differentiation of stem cells. However, the cellular mechanisms during bone formation remain largely unknown. Factors such as wavelength, energy density, irradiation, and frequency of LLLT influence the cellular mechanisms, and the effects of LLLT vary according to cell types treated. This review aims to summarize the current knowledge of the molecular pathways activated by LLLT and its effects on the bone healing process to improve its clinical application.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Review
Engineering, Biomedical
Guanyin Zhu, Tianxu Zhang, Miao Chen, Ke Yao, Xinqi Huang, Bo Zhang, Yazhen Li, Jun Liu, Yunbing Wang, Zhihe Zhao
Summary: Bone-tissue defects are a global issue, with autologous and allogeneic bone grafting failing to achieve ideal therapeutic effects. This has led researchers to explore novel bone-regeneration methods, with the development of BTE scaffolds at the forefront. By delving into bone physiology and healing mechanisms, biomimicking and bioinspired BTE scaffolds are making progress.
BIOACTIVE MATERIALS
(2021)
Review
Biotechnology & Applied Microbiology
Gretel S. Major, Jeremy W. Simcock, Tim B. F. Wood, Khoon S. Lim
Summary: Autologous fat grafting shows promise in repairing soft tissue deformities, but engineered solutions are needed to improve adipose tissue survival due to high resorption rates. Advances in material development and biofabrication have laid the foundation for functional adipose tissue constructs, but a balance is required between clinically feasible delivery and enhanced graft structural integrity. A new approach that combines clinical and research objectives can assist in developing mature adipose tissue constructs with controlled spatial arrangement and increased potential for neovascularization.
TRENDS IN BIOTECHNOLOGY
(2022)
Article
Cell & Tissue Engineering
Payal Ganguly, Jehan J. El-Jawhari, Agata N. Burska, Frederique Ponchel, Peter Giannoudis, Elena A. Jones
STEM CELLS INTERNATIONAL
(2019)
Article
Critical Care Medicine
H-C Pape, S. Halvachizadeh, L. Leenen, G. D. Velmahos, R. Buckley, P. Giannoudis
INJURY-INTERNATIONAL JOURNAL OF THE CARE OF THE INJURED
(2019)
Article
Multidisciplinary Sciences
A. D. Anastasiou, M. Nerantzaki, E. Gounari, M. S. Duggal, P. V. Giannoudis, A. Jha, D. Bikiaris
SCIENTIFIC REPORTS
(2019)
Article
Multidisciplinary Sciences
Jehan J. El-Jawhari, George Kleftouris, Yasser El-Sherbiny, Hany Saleeb, Robert M. West, Elena Jones, Peter V. Giannoudis
SCIENTIFIC REPORTS
(2019)
Article
Orthopedics
S. Petrou, B. Parker, J. Masters, J. Achten, J. Bruce, S. E. Lamb, N. Parsons, M. L. Costa, Keith Willett, Damian Griffin, Steven Jeffery, Jill Arrowsmith, Gorav Datta, Mick Dennison, Mark Farrar, Peter Giannoudis, Andrew Gray, Philip Henman, Peter Hull, Umraz Khan, Charlotte Lewis, David Loveday, Jitendra Mangwani, Andrew McAndrew, Damian McClelland, Mike McNicholas, David Noyes, Ben Ollivere, Ian Pallister, Keith Porter, Manoj Ramachandran, Rory Rickard, Benedict Rogers, Hemant Sharma, Mel Tavakkolizadeh, Jonathan Young
BONE & JOINT JOURNAL
(2019)
Article
Cell & Tissue Engineering
Heather E. Owston, Payal Ganguly, Giuseppe Tronci, Stephen J. Russell, Peter V. Giannoudis, Elena A. Jones
STEM CELLS INTERNATIONAL
(2019)
Review
Medicine, General & Internal
Louise Johnson, Emily Igoe, George Kleftouris, Ioannis Papachristos, Costas Papakostidis, Peter Giannoudis
JOURNAL OF CLINICAL MEDICINE
(2019)
Article
Medicine, General & Internal
Theodoros H. Tosounidis, Colin Holton, Vasileios P. Giannoudis, Nikolaos K. Kanakaris, Robert M. West, Peter V. Giannoudis
Summary: Study investigated correlation between elevated CRP and WBC levels in nonunion patients, finding elevated CRP levels increased infection risk. WBC count unreliable for predicting infection. All cases achieved solid union post-revision surgery.
JOURNAL OF CLINICAL MEDICINE
(2021)
Article
Medicine, General & Internal
Michalis Panteli, Marilena P. Giannoudi, Christopher J. Lodge, Robert M. West, Ippokratis Pountos, Peter V. Giannoudis
Summary: This study aimed to define the incidence of subtrochanteric femoral fractures and investigate associations with mortality and medical complications following intramedullary nail treatment. Risk factors for mortality included low albumin, dementia, pneumonia, and high Charlson comorbidity score. Factors such as ICU/HDU stay, asthma/COPD, and prolonged hospital stay were associated with higher incidence of hospital acquired pneumonia. Early identification of these factors could aid in prognostication and prevention of poor outcomes.
JOURNAL OF CLINICAL MEDICINE
(2021)
Review
Medicine, General & Internal
Dionysios J. Papachristou, Stavros Georgopoulos, Peter Giannoudis, Elias Panagiotopoulos
Summary: Fracture-healing is a complex process that may fail, leading to delayed unions or non-unions. Research and clinical studies are focusing on unraveling the mechanisms regulating fracture-healing, aiming to develop more effective therapeutic strategies.
JOURNAL OF CLINICAL MEDICINE
(2021)
Article
Medicine, General & Internal
Michalis Panteli, James S. H. Vun, Robert M. West, Anthony Howard, Ippokratis Pountos, Peter V. Giannoudis
Summary: This study aimed to investigate the incidence, risk factors and pathogenic microorganisms causing infection in patients with subtrochanteric femoral fractures managed with an intramedullary nail. Deep infection was associated with non-union, open fracture, massive transfusion, post-operative transfusion and prolonged length of stay. Staphylococcus aureus and coliforms were the most common microorganisms identified in superficial and deep infections, respectively, with polymicrobial infection present in a significant proportion of cases.
JOURNAL OF CLINICAL MEDICINE
(2021)
Article
Medicine, General & Internal
Michalis Panteli, James S. H. Vun, Robert M. West, Anthony J. Howard, Ippokratis Pountos, Peter V. Giannoudis
Summary: This study developed and validated a predictive model for non-union following subtrochanteric fractures of the femur. By identifying risk factors and creating a risk score, high-risk patients can be identified early post-operatively. The scoring system demonstrated good discriminatory capability, calibration, and internal validity, providing valuable information for surgeons to intervene and modify surgery-related factors to reduce the risk of non-union.
JOURNAL OF CLINICAL MEDICINE
(2021)
Review
Medicine, General & Internal
Angelos Kaspiris, Argyris C. Hadjimichael, Elias S. Vasiliadis, Dionysios J. Papachristou, Peter V. Giannoudis, Elias C. Panagiotopoulos
Summary: This study investigated the clinical implantation of growth factors for intraoperative enhancement of osteogenesis in the treatment of long bone fractures and non-unions. The results showed that the application of BMP-2 and -7, PRP, and MSCs significantly increased the effectiveness of fracture treatment and postoperative functional scores.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Medicine, General & Internal
James Tebby, Vasileios P. Giannoudis, Sophia M. Wakefield, Fiona Lecky, Omar Bouamra, Peter V. Giannoudis
Summary: Managing patients with multiple injuries, especially those with comorbidities such as diabetes mellitus, remains challenging and increases mortality. This study investigates the impact of major trauma centres in the UK on the outcomes of polytrauma patients with diabetes. The findings show that while overall mortality has decreased, patients with diabetes still had higher mortality compared to other groups, highlighting diabetes as an independent risk factor for mortality in polytrauma patients.
JOURNAL OF CLINICAL MEDICINE
(2023)
Review
Biotechnology & Applied Microbiology
Jehan J. El-Jawhari, Payal Ganguly, Elena Jones, Peter Giannoudis
Summary: This review discusses the application of bone marrow-derived mesenchymal stromal cells in treating osteonecrosis, including donor-related factors, the impact of aging on donor-related variability, and factors influencing the quantity and function of these cells.
BIOENGINEERING-BASEL
(2021)
Article
Critical Care Medicine
Andrija Jurina, Valentina Delimar, Zlatko Giljevic, Tajana Filipec Kanizaj, Andro Matkovic, Dinko Vidovic, Nikolina Jurjevic, Vinko Vidjak, Zeljko Duic, Mario Cuk, Mladen Japjec, Tomislav Dujmovic, Andrea Radeljak, Mirjana Marjana Kardum Paro, Marijana Vucic-Lovrencic, Mario Staresinic
Summary: This study investigated the prevalence of fragility spinal fractures among liver transplant candidates with cirrhosis. The results showed the detrimental impact of chronic liver disease and hepatic osteodystrophy on bone strength, and the correlation between DXA measurement and lumbar fragility fractures. These findings highlight the importance of adequate bone evaluation in liver transplant candidates.
INJURY-INTERNATIONAL JOURNAL OF THE CARE OF THE INJURED
(2024)
Article
Critical Care Medicine
M. Scrivano, A. Vadal, G. Fedeli, R. Di Niccolo, D. Topa, S. Porcino, F. Pallotta, A. De Carli
Summary: This study compares the outcomes and complications of Ilioinguinal versus modified Stoppa approach in Open Reduction and Internal Fixation (ORIF) of anterior column acetabulum fractures. The results show that the modified Stoppa approach has a shorter operative time, less intra-operative blood loss, and fewer complications. The ilioinguinal approach achieves better anatomic reduction. However, there were no significant differences in terms of vascular lesions, clinical and functional outcomes between the two groups.
INJURY-INTERNATIONAL JOURNAL OF THE CARE OF THE INJURED
(2024)
Article
Critical Care Medicine
Jacob Hartline, Christopher T. Cosgrove, Nathan N. O'Hara, Qasim M. Ghulam, Zachary D. Hannan, Robert V. O'Toole, Marcus F. Sciadini, Christopher G. Langhammer
Summary: In a young, healthy orthopedic trauma population with isolated extremity injury, traditional demographic factors and ballistic injury mechanism have a greater predictive value for long-term mortality after hospital discharge compared to popular markers of socioeconomic status.
INJURY-INTERNATIONAL JOURNAL OF THE CARE OF THE INJURED
(2024)
Article
Critical Care Medicine
Youngmin Kwon, Jihye Lim, Chunui Lee
Summary: This study aims to investigate dental traumatic injuries related to standing electric scooters and compare them with injuries caused by other factors. The results indicate that crown-root fractures and avulsions are more common in electric scooter accidents. Additionally, relatively minor dental injuries, such as concussions and subluxations, are more likely to occur as combined injuries in electric scooter accidents. The study suggests the need for strengthened policies and enforcement of laws to prevent severe dental and craniofacial trauma associated with electric scooter use.
INJURY-INTERNATIONAL JOURNAL OF THE CARE OF THE INJURED
(2024)
Article
Critical Care Medicine
Louise Kruse Jensen, Henrik Elvang Jensen, Hans Gottlieb
Summary: This study describes the histopathology of debrided bone tissue in chronic osteomyelitis (CO). The inflammatory response still exists after debridement, although it fades from the center. Sampling of debrided bone tissue must be performed initially during surgery to avoid underestimation of neutrophil infiltration.
INJURY-INTERNATIONAL JOURNAL OF THE CARE OF THE INJURED
(2024)
Article
Critical Care Medicine
Alejandro Alejandrez, Motasem Refaat, Yeng Vue
Summary: This study aims to assess the rate of operative fixation of sacral fractures in pelvises with dysmorphic and nondysmorphic sacrums, as well as whether a difference exists in fracture morphology between groups. The study found no statistical difference in operative fixation rates between pelvises with dysmorphic and nondysmorphic sacrums, but a difference in fracture patterns was observed.
INJURY-INTERNATIONAL JOURNAL OF THE CARE OF THE INJURED
(2024)
Article
Critical Care Medicine
Dong Wang, Shuo Diao, Xiaobin Zhou, Junlin Zhou, Yang Liu
Summary: This study discussed the role of fracture site tissue exosomes lncRNAs-mRNAs networks on post-injury adaptation (PIA) promoting bone mesenchymal stem cells (BMSCs) proliferation and migration. The results confirmed that PIA accelerated BMSCs proliferation and migration, and identified tissue exosomes as the key factor in this process. By analyzing the tissue exosomes lncRNAs-mRNAs networks, several hub genes, such as Akt1, Actb, and Uba52, were identified, and Kif11 was found to be a key gene in BMSCs regulated by tissue-derived exosomes of PIA treated rats.
INJURY-INTERNATIONAL JOURNAL OF THE CARE OF THE INJURED
(2024)
Article
Critical Care Medicine
Lisa Reider, Jason R. Falvey, Safiyyah M. Okoye, Jennifer L. Wolff, Joseph F. Levy
Summary: Falls are a leading cause of injury and hospital readmissions in older adults, with over 3 million seeking hospital care for fall injuries annually in the United States. The annual acute treatment costs for these injuries amount to $20 billion, indicating the urgent need for evidence-based fall prevention interventions and investments in geriatric emergency departments.
INJURY-INTERNATIONAL JOURNAL OF THE CARE OF THE INJURED
(2024)
Article
Critical Care Medicine
Mohamed Elbuzidi, Alyssa N. Wenzel, Andrew Harris, Majd Marrache, Julius K. Oni, Harpal S. Khanuja, Vishal Hegde
Summary: A retrospective propensity score matched cohort study was conducted using the American College of Surgeons National Surgical Quality Improvement Program (NSQIP) database to compare outcomes for patients with recently diagnosed COVID-19 infection and those without COVID-19 infection undergoing operative treatment of hip fractures. The results showed that COVID-19-positive patients had a higher risk of 30-day mortality, pneumonia, unplanned intubation, septic shock, longer length of hospital stay, and discharge to an acute care hospital. Active COVID-19 infection is an independent risk factor for complications and increased resource utilization in these patients.
INJURY-INTERNATIONAL JOURNAL OF THE CARE OF THE INJURED
(2024)
Review
Critical Care Medicine
Jorge Mayor, Vera Birgel, Jan-Dierk Clausen, Goekmen Aktas, Stephan Sehmisch, Ann-Kathrin Einfeldt, Vasilis Giannoudis, Ahmed H. K. Abdelaal, Emmanouil Liodakis
Summary: This study provides a comprehensive overview of biomechanical research on the treatment of intertrochanteric fractures using cephalomedullary devices. Through a systematic literature search and synthesis analysis, the study highlights the need for standardization in biomechanical studies, and suggests strategies to enhance construct stability. The findings emphasize the importance of further research and meta-analyses to establish standardized protocols and enhance reliability.
INJURY-INTERNATIONAL JOURNAL OF THE CARE OF THE INJURED
(2024)
Article
Critical Care Medicine
Patricia Rodarte, Jamieson O'Marr, Billy Haonga, Deogratias Patrick, Kian Niknam, Mayur Urva, Abigail Cortez, Willem-Jan Metsemakers, David Shearer, Saam Morshed
Summary: This study evaluates the diagnostic performance of telephone questionnaires in identifying patients with fracture-related infections (FRIs) after open tibia fracture fixation in Tanzania. The study shows that telephone questionnaires have adequate diagnostic performance, with drainage being the main indicator for FRIs.
INJURY-INTERNATIONAL JOURNAL OF THE CARE OF THE INJURED
(2024)
Review
Critical Care Medicine
Zhiyi Liu, Guodong Hou, Wencong Zhang, Junyan Lin, Jinrong Yin, Huan Chen, Guowei Huang, Aiguo Li
Summary: Calcaneal tuberosity avulsion fracture, an extra-articular injury, is a rare fracture caused internally by intense contraction of the gastrocnemius-soleus complex, and externally by low-energy (possibly high-energy). The risk of injuries to the skin and Achilles tendon around the calcaneal tuberosity is closely related to the Lee classification and Carnero-Martin de Soto Classification of this type of fracture. Diagnosis is typically confirmed through X-ray, digital imaging, and CT, but MRI should also be used to assess the soft tissue. Recent advances in understanding this fracture have led to the development of different internal fixation devices and surgical procedures that provide stable fracture reduction and resistance to Achilles tendon forces. This article reviews the new insights into the anatomy, classification, risk factors, and treatment modalities of calcaneal tuberosity avulsion fracture in recent years.
INJURY-INTERNATIONAL JOURNAL OF THE CARE OF THE INJURED
(2024)
Article
Critical Care Medicine
Win Wah, Janneke Berecki-Gisolf, Karen Walker-Bone
Summary: This study aimed to identify the incidence and factors associated with in-hospital complications of work-related musculoskeletal injuries. The results showed that age, gender, area-level disadvantage, hospital type, comorbidity, emergency admissions, anesthesia, and the type of injury were all associated with in-hospital complications. The most common complications were cardiovascular, gastrointestinal complications and adverse drug events.
INJURY-INTERNATIONAL JOURNAL OF THE CARE OF THE INJURED
(2024)
Article
Critical Care Medicine
Gareth Rooke, Paul Sharplin, Richard Buckley
Summary: A 31-year-old female suffered a right fibula fracture with deltoid ligament injury after falling while climbing on wet rocks. She had ORIF surgery and recovered well, but has developed vague pain and hardware sensation at the lateral ankle 6 months later. Her past medical history includes breast reduction surgery and vaginal delivery, and she has a social history of alcohol consumption and past recreational drug use.
INJURY-INTERNATIONAL JOURNAL OF THE CARE OF THE INJURED
(2024)
Review
Critical Care Medicine
Yuwei Wen, Danjiang Zhu, Qiang Wang, Baojian Song, Wei Feng
Summary: This study compared the clinical outcomes of compression screw and non-weight-bearing techniques in treating pediatric Jones fractures. The results showed that compared to non-weight-bearing techniques, compression screw fixation can shorten the radiographic union time, immobilization time, and facilitate earlier return to full weight bearing and daily life. We recommend the use of compression screw fixation for widely displaced fractures and school-age active adolescents.
INJURY-INTERNATIONAL JOURNAL OF THE CARE OF THE INJURED
(2024)