Toxoplasma gondii Rhoptry 16 Kinase Promotes Host Resistance to Oral Infection and Intestinal Inflammation Only in the Context of the Dense Granule Protein GRA15

The Cytokines Interleukin 27 and Interferon-γ Promote Distinct Treg Cell Populations Required to Limit Infection-Induced Pathology

(2012) Aisling O’Hara Hall et al.   IMMUNITY

Interleukin-15-Dependent NKp46+ Innate Lymphoid Cells Control Intestinal Inflammation by Recruiting Inflammatory Monocytes

(2012) Julie Schulthess et al.   IMMUNITY

A Cluster of Interferon-γ-Inducible p65 GTPases Plays a Critical Role in Host Defense against Toxoplasma gondii

(2012) Masahiro Yamamoto et al.   IMMUNITY

Parasite-induced TH1 cells and intestinal dysbiosis cooperate in IFN-γ-dependent elimination of Paneth cells

(2012) Megan Raetz et al.   NATURE IMMUNOLOGY

Integrated Bioinformatic and Targeted Deletion Analyses of the SRS Gene Superfamily Identify SRS29C as a Negative Regulator of Toxoplasma Virulence

(2012) J. D. Wasmuth et al.   mBio

The Rhoptry Proteins ROP18 and ROP5 Mediate Toxoplasma gondii Evasion of the Murine, But Not the Human, Interferon-Gamma Response

(2012) Wendy Niedelman et al.   PLoS Pathogens

A Critical Role for SOCS3 in Innate Resistance to Toxoplasma gondii

(2011) Ryan J. Whitmarsh et al.   Cell Host & Microbe

Toxoplasma Polymorphic Effectors Determine Macrophage Polarization and Intestinal Inflammation

(2011) Kirk D.C. Jensen et al.   Cell Host & Microbe

Insights into inflammatory bowel disease using Toxoplasma gondii as an infectious trigger

(2011) Charlotte E Egan et al.   IMMUNOLOGY AND CELL BIOLOGY

Targeted Disruption of Toxoplasma gondii Serine Protease Inhibitor 1 Increases Bradyzoite Cyst FormationIn Vitroand Parasite Tissue Burden in Mice

(2011) Viviana Pszenny et al.   INFECTION AND IMMUNITY

Strain-specific activation of the NF-κB pathway by GRA15, a novelToxoplasma gondiidense granule protein

(2011) Emily E. Rosowski et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Determinants of GBP Recruitment to Toxoplasma gondii Vacuoles and the Parasitic Factors That Control It

(2011) Sebastian Virreira Winter et al.   PLoS One

Control of Toxoplasma reactivation by rescue of dysfunctional CD8+ T-cell response via PD-1-PDL-1 blockade

(2011) R. Bhadra et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Toxoplasma gondii effectors are master regulators of the inflammatory response

(2011) Mariane B. Melo et al.   TRENDS IN PARASITOLOGY

Toxoplasma gondii Rhoptry Kinase ROP16 Activates STAT3 and STAT6 Resulting in Cytokine Inhibition and Arginase-1-Dependent Growth Control

(2011) Barbara A. Butcher et al.   PLoS Pathogens

Alternatively activated macrophages inhibit T-cell proliferation by Stat6-dependent expression of PD-L2

(2010) S. Huber et al.   BLOOD

CD4 T-Cell Suppression by Cells from Toxoplasma gondii-Infected Retinas Is Mediated by Surface Protein PD-L1

(2010) E. Charles et al.   INFECTION AND IMMUNITY

ToxoplasmaRhoptry Protein 16 (ROP16) Subverts Host Function by Direct Tyrosine Phosphorylation of STAT6

(2010) Yi-Ching Ong et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Small intestinal inflammation following oral infection with Toxoplasma gondii does not occur exclusively in C57BL/6 mice: review of 70 reports from the literature

(2010) Maximilian Schreiner et al.   MEMORIAS DO INSTITUTO OSWALDO CRUZ

GM-CSF: a role in immune and inflammatory reactions in the intestine

(2010) Laia Egea et al.   Expert Review of Gastroenterology & Hepatology

Decrease of Foxp3+ Treg Cell Number and Acquisition of Effector Cell Phenotype during Lethal Infection

(2009) Guillaume Oldenhove et al.   IMMUNITY

A single polymorphic amino acid onToxoplasma gondiikinase ROP16 determines the direct and strain-specific activation of Stat3

(2009) Masahiro Yamamoto et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Interleukin (IL)-23 mediatesToxoplasma gondii–induced immunopathology in the gut via matrixmetalloproteinase-2 and IL-22 but independent of IL-17

(2009) Melba Muñoz et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Virulent Toxoplasma gondii Evade Immunity-Related GTPase-Mediated Parasite Vacuole Disruption within Primed Macrophages

(2009) Y. Zhao et al.   JOURNAL OF IMMUNOLOGY

PD-1 and Its Ligands in Tolerance and Immunity

(2008) Mary E. Keir et al.   Annual Review of Immunology

Alternative Activation of Macrophages: An Immunologic Functional Perspective

(2008) Fernando O. Martinez et al.   Annual Review of Immunology

Specific Microbiota Direct the Differentiation of IL-17-Producing T-Helper Cells in the Mucosa of the Small Intestine

(2008) Ivaylo I. Ivanov et al.   Cell Host & Microbe

Gr1+ Inflammatory Monocytes Are Required for Mucosal Resistance to the Pathogen Toxoplasma gondii

(2008) Ildiko R. Dunay et al.   IMMUNITY

Toll-like receptor–induced arginase 1 in macrophages thwarts effective immunity against intracellular pathogens

(2008) Karim C El Kasmi et al.   NATURE IMMUNOLOGY