Regulation of TNF-α with a focus on rheumatoid arthritis

Signal transduction by tumor necrosis factor receptors

(2012) Lucía Cabal-Hierro et al.   CELLULAR SIGNALLING

Citrullination of TNF-α by peptidylarginine deiminases reduces its capacity to stimulate the production of inflammatory chemokines

(2012) Eva A.V. Moelants et al.   CYTOKINE

Induction of osteoclastogenesis and bone loss by human autoantibodies against citrullinated vimentin

(2012) Ulrike Harre et al.   JOURNAL OF CLINICAL INVESTIGATION

miRNA-125b regulates TNF-α production in CD14+ neonatal monocytes via post-transcriptional regulation

(2012) Hsin-Chun Huang et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Bone erosion in rheumatoid arthritis: mechanisms, diagnosis and treatment

(2012) Georg Schett et al.   Nature Reviews Rheumatology

Anti-TNF therapy

(2011) Nishanthi Thalayasingam et al.   BEST PRACTICE & RESEARCH IN CLINICAL RHEUMATOLOGY

Efficacy and safety of the human anti-IL-1beta monoclonal antibody canakinumab in rheumatoid arthritis: results of a 12-week, phase II, dose-finding study

(2011) Rieke Alten et al.   BMC MUSCULOSKELETAL DISORDERS

Tumor necrosis factor receptor cross-talk

(2011) Petrus J. W. Naudé et al.   FEBS Journal

Transcriptional regulation of TNF/LT locus in immune cells

(2011) Yu. V. Shebzukhov et al.   MOLECULAR BIOLOGY

Positive regulators of osteoclastogenesis and bone resorption in rheumatoid arthritis

(2011) Tobias Braun et al.   ARTHRITIS RESEARCH & THERAPY

CCR5 blockade in rheumatoid arthritis: a randomised, double-blind, placebo-controlled clinical trial

(2010) A. W. R. van Kuijk et al.   ANNALS OF THE RHEUMATIC DISEASES

Calcium signaling in osteoclasts

(2010) Sung-Yong Hwang et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

CC Chemokine Receptor Small Molecule Antagonists in the Treatment of Rheumatoid Arthritis and Other Diseases: A Current View

(2010) Jinqi Liu et al.   CURRENT TOPICS IN MEDICINAL CHEMISTRY

The role of Natural Killer cells in the pathogenesis of rheumatoid arthritis: Major contributors or essential homeostatic modulators?

(2010) David J. Ahern et al.   IMMUNOLOGY LETTERS

TNF receptor 2 pathway: drug target for autoimmune diseases

(2010) Denise Faustman et al.   NATURE REVIEWS DRUG DISCOVERY

Solution of the Structure of the TNF-TNFR2 Complex

(2010) Y. Mukai et al.   Science Signaling

Crystallization and preliminary X-ray analysis of the tumour necrosis factor α–tumour necrosis factor receptor type 2 complex

(2009) Yohei Mukai et al.   Acta Crystallographica Section F-Structural Biology and Crystallization Communications

Gene-environment interaction between the DRB1 shared epitope and smoking in the risk of anti-citrullinated protein antibody-positive rheumatoid arthritis: All alleles are important

(2009) Emeli Lundström et al.   ARTHRITIS AND RHEUMATISM

Predicting the future of anti-tumor necrosis factor therapy

(2009) Cornelis L Verweij   ARTHRITIS RESEARCH & THERAPY

Tyrosine Kinases Btk and Tec Regulate Osteoclast Differentiation by Linking RANK and ITAM Signals

(2008) Masahiro Shinohara et al.   CELL

Evidence that cytokines play a role in rheumatoid arthritis

(2008) Fionula M. Brennan et al.   JOURNAL OF CLINICAL INVESTIGATION

Structure–Function Relationship of Tumor Necrosis Factor (TNF) and Its Receptor Interaction Based on 3D Structural Analysis of a Fully Active TNFR1-Selective TNF Mutant

(2008) Yohei Mukai et al.   JOURNAL OF MOLECULAR BIOLOGY

TNF-mediated inflammatory disease

(2007) JR Bradley   JOURNAL OF PATHOLOGY

MicroRNA targets in immune genes and the Dicer/Argonaute and ARE machinery components

(2007) Ananthi J. Asirvatham et al.   MOLECULAR IMMUNOLOGY