Regulation of B-cell development and function by microRNAs

Germinal Centers

(2012) Gabriel D. Victora et al.   Annual Review of Immunology

miR-155 regulates IFN-  production in natural killer cells

(2012) R. Trotta et al.   BLOOD

Btk levels set the threshold for B-cell activation and negative selection of autoreactive B cells in mice

(2012) L. P. Kil et al.   BLOOD

Roles for MicroRNAs in Conferring Robustness to Biological Processes

(2012) Margaret S. Ebert et al.   CELL

Single-Cell Expression Analyses during Cellular Reprogramming Reveal an Early Stochastic and a Late Hierarchic Phase

(2012) Yosef Buganim et al.   CELL

B-1 B Cell Development in the Fetus and Adult

(2012) Encarnacion Montecino-Rodriguez et al.   IMMUNITY

BCL6 positively regulates AID and germinal center gene expression via repression of miR-155

(2012) Katia Basso et al.   JOURNAL OF EXPERIMENTAL MEDICINE

The emerging role of MIR-146A in the control of hematopoiesis, immune function and cancer

(2012) Catherine Labbaye et al.   Journal of Hematology & Oncology

High-throughput assessment of microRNA activity and function using microRNA sensor and decoy libraries

(2012) Gavriel Mullokandov et al.   NATURE METHODS

MicroRNA profiling: approaches and considerations

(2012) Colin C. Pritchard et al.   NATURE REVIEWS GENETICS

MicroRNAs miR-125a and miR-125b constitutively activate the NF- B pathway by targeting the tumor necrosis factor alpha-induced protein 3 (TNFAIP3, A20)

(2012) S.-W. Kim et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Oncomir miR-125b regulates hematopoiesis by targeting the gene Lin28A

(2012) A. A. Chaudhuri et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Lin28b Reprograms Adult Bone Marrow Hematopoietic Progenitors to Mediate Fetal-Like Lymphopoiesis

(2012) Joan Yuan et al.   SCIENCE

How does Lin28 let-7 control development and disease?

(2012) James E. Thornton et al.   TRENDS IN CELL BIOLOGY

Intact p53-Dependent Responses in miR-34–Deficient Mice

(2012) Carla P. Concepcion et al.   PLoS Genetics

Modulating the Strength and Threshold of NOTCH Oncogenic Signals by mir-181a-1/b-1

(2012) Rita Fragoso et al.   PLoS Genetics

The RNase III enzyme Dicer is essential for germinal center B-cell formation

(2011) S. Xu et al.   BLOOD

miR-155 regulates HGAL expression and increases lymphoma cell motility

(2011) L. N. Dagan et al.   BLOOD

MicroRNA control of lymphocyte differentiation and function

(2011) Laura Belver et al.   CURRENT OPINION IN IMMUNOLOGY

Intercellular and systemic movement of RNA silencing signals

(2011) Charles W Melnyk et al.   EMBO JOURNAL

MicroRNA-125b Potentiates Macrophage Activation

(2011) Aadel A. Chaudhuri et al.   JOURNAL OF IMMUNOLOGY

Eμ/miR-125b transgenic mice develop lethal B-cell malignancies

(2011) Y Enomoto et al.   LEUKEMIA

Alternative miRNA Biogenesis Pathways and the Interpretation of Core miRNA Pathway Mutants

(2011) Jr-Shiuan Yang et al.   MOLECULAR CELL

Mutator activity induced by microRNA-155 (miR-155) links inflammation and cancer

(2011) E. Tili et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

NF- B dysregulation in microRNA-146a-deficient mice drives the development of myeloid malignancies

(2011) J. L. Zhao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Unidirectional transfer of microRNA-loaded exosomes from T cells to antigen-presenting cells

(2011) María Mittelbrunn et al.   Nature Communications

Biochemical Principles of Small RNA Pathways

(2010) Qinghua Liu et al.   Annual Review of Biochemistry

Downregulation of p53-inducible microRNAs 192, 194, and 215 Impairs the p53/MDM2 Autoregulatory Loop in Multiple Myeloma Development

(2010) Flavia Pichiorri et al.   CANCER CELL

The DLEU2/miR-15a/16-1 Cluster Controls B Cell Proliferation and Its Deletion Leads to Chronic Lymphocytic Leukemia

(2010) Ulf Klein et al.   CANCER CELL

Lin28: A MicroRNA Regulator with a Macro Role

(2010) Srinivas R. Viswanathan et al.   CELL

Transcriptome-wide Identification of RNA-Binding Protein and MicroRNA Target Sites by PAR-CLIP

(2010) Markus Hafner et al.   CELL

Regulation of MicroRNA Expression and Abundance during Lymphopoiesis

(2010) Stefan Kuchen et al.   IMMUNITY

MicroRNAs Prevent the Generation of Autoreactive Antibodies

(2010) Laura Belver et al.   IMMUNITY

MicroRNA-155 Promotes Autoimmune Inflammation by Enhancing Inflammatory T Cell Development

(2010) Ryan M. O'Connell et al.   IMMUNITY

MicroRNA-34a Perturbs B Lymphocyte Development by Repressing the Forkhead Box Transcription Factor Foxp1

(2010) Dinesh S. Rao et al.   IMMUNITY

MicroRNA 125b inhibition of B cell differentiation in germinal centers

(2010) Murali Gururajan et al.   INTERNATIONAL IMMUNOLOGY

OncomiR addiction in an in vivo model of microRNA-21-induced pre-B-cell lymphoma

(2010) Pedro P. Medina et al.   NATURE

A dicer-independent miRNA biogenesis pathway that requires Ago catalysis

(2010) Sihem Cheloufi et al.   NATURE

Targeting microRNAs in cancer: rationale, strategies and challenges

(2010) Ramiro Garzon et al.   NATURE REVIEWS DRUG DISCOVERY

Chronic lymphocytic leukemia modeled in mouse by targeted miR-29 expression

(2010) U. Santanam et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Modulation of mismatch repair and genomic stability by miR-155

(2010) N. Valeri et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Bruton tyrosine kinase inhibitor PCI-32765 blocks B-cell activation and is efficacious in models of autoimmune disease and B-cell malignancy

(2010) L. A. Honigberg et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

MicroRNAs enriched in hematopoietic stem cells differentially regulate long-term hematopoietic output

(2010) R. M. O'Connell et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Conserved vertebrate mir-451 provides a platform for Dicer-independent, Ago2-mediated microRNA biogenesis

(2010) J.-S. Yang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Targeting of SMAD5 links microRNA-155 to the TGF-  pathway and lymphomagenesis

(2010) D. Rai et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A Novel miRNA Processing Pathway Independent of Dicer Requires Argonaute2 Catalytic Activity

(2010) D. Cifuentes et al.   SCIENCE

MicroRNAs in Cancer

(2009) Ramiro Garzon et al.   Annual Review of Medicine

Copy number abnormalities, MYC activity, and the genetic fingerprint of normal B cells mechanistically define the microRNA profile of diffuse large B-cell lymphoma

(2009) C. Li et al.   BLOOD

Karyotype-specific microRNA signature in chronic lymphocytic leukemia

(2009) R. Visone et al.   BLOOD

Src homology 2 domain-containing inositol-5-phosphatase and CCAAT enhancer-binding protein   are targeted by miR-155 in B cells of E -MiR-155 transgenic mice

(2009) S. Costinean et al.   BLOOD

MicroRNA Control in the Immune System: Basic Principles

(2009) Changchun Xiao et al.   CELL

Origin, Biogenesis, and Activity of Plant MicroRNAs

(2009) Olivier Voinnet   CELL

MicroRNAs: Target Recognition and Regulatory Functions

(2009) David P. Bartel   CELL

The miR-34 family in cancer and apoptosis

(2009) H Hermeking   CELL DEATH AND DIFFERENTIATION

Onco-miR-155 targets SHIP1 to promote TNFα-dependent growth of B cell lymphomas

(2009) Irene M. Pedersen et al.   EMBO Molecular Medicine

Genetic dissection of the miR-17 92 cluster of microRNAs in Myc-induced B-cell lymphomas

(2009) P. Mu et al.   GENES & DEVELOPMENT

miR-19 is a key oncogenic component of mir-17-92

(2009) V. Olive et al.   GENES & DEVELOPMENT

Identification of the Human Mature B Cell miRNome

(2009) Katia Basso et al.   IMMUNITY

miR-155: On the Crosstalk Between Inflammation and Cancer

(2009) Esmerina Tili et al.   INTERNATIONAL REVIEWS OF IMMUNOLOGY

An endogenous positively selecting peptide enhances mature T cell responses and becomes an autoantigen in the absence of microRNA miR-181a

(2009) Peter J R Ebert et al.   NATURE IMMUNOLOGY

Features of Mammalian microRNA Promoters Emerge from Polymerase II Chromatin Immunoprecipitation Data

(2009) David L. Corcoran et al.   PLoS One

The Biochemistry of Somatic Hypermutation

(2008) Jonathan U. Peled et al.   Annual Review of Immunology

Mechanism and Regulation of Class Switch Recombination

(2008) Janet Stavnezer et al.   Annual Review of Immunology

MicroRNA expression profiling in relation to the genetic heterogeneity of acute myeloid leukemia

(2008) M. Jongen-Lavrencic et al.   BLOOD

Differentiation stage-specific expression of microRNAs in B lymphocytes and diffuse large B-cell lymphomas

(2008) R. Malumbres et al.   BLOOD

Dicer Ablation Affects Antibody Diversity and Cell Survival in the B Lymphocyte Lineage

(2008) Sergei B. Koralov et al.   CELL

Targeted Deletion Reveals Essential and Overlapping Functions of the miR-17∼92 Family of miRNA Clusters

(2008) Andrea Ventura et al.   CELL

AID Is Required for the Chromosomal Breaks in c-myc that Lead to c-myc/IgH Translocations

(2008) Davide F. Robbiani et al.   CELL

Peripheral B cell subsets

(2008) David Allman et al.   CURRENT OPINION IN IMMUNOLOGY

Chromatin structure analyses identify miRNA promoters

(2008) F. Ozsolak et al.   GENES & DEVELOPMENT

MicroRNA-155 Is a Negative Regulator of Activation-Induced Cytidine Deaminase

(2008) Grace Teng et al.   IMMUNITY

MicroRNA-155 Suppresses Activation-Induced Cytidine Deaminase-Mediated Myc-Igh Translocation

(2008) Yair Dorsett et al.   IMMUNITY

AID expression levels determine the extent ofcMyconcogenic translocations and the incidence of B cell tumor development

(2008) Makiko Takizawa et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Sustained expression of microRNA-155 in hematopoietic stem cells causes a myeloproliferative disorder

(2008) Ryan M. O'Connell et al.   JOURNAL OF EXPERIMENTAL MEDICINE

miR-181b negatively regulates activation-induced cytidine deaminase in B cells

(2008) Virginia G. de Yébenes et al.   JOURNAL OF EXPERIMENTAL MEDICINE

The impact of microRNAs on protein output

(2008) Daehyun Baek et al.   NATURE

Widespread changes in protein synthesis induced by microRNAs

(2008) Matthias Selbach et al.   NATURE

Two levels of protection for the B cell genome during somatic hypermutation

(2008) Man Liu et al.   NATURE

Lymphoproliferative disease and autoimmunity in mice with increased miR-17-92 expression in lymphocytes

(2008) Changchun Xiao et al.   NATURE IMMUNOLOGY

Stable knockdown of microRNA in vivo by lentiviral vectors

(2008) Bernhard Gentner et al.   NATURE METHODS

Haploinsufficiency of Activation-Induced Deaminase for Antibody Diversification and Chromosome Translocations both In Vitro and In Vivo

(2008) Isora V. Sernández et al.   PLoS One