The emerging role of MIR-146A in the control of hematopoiesis, immune function and cancer

Macrophage development from HSCs requires PU.1-coordinated microRNA expression

(2011) S. Ghani et al.   BLOOD

MicroRNAs in platelet production and activation

(2011) L. C. Edelstein et al.   BLOOD

MicroRNA-146a Downregulates NF B Activity via Targeting TRAF6 and Functions as a Tumor Suppressor Having Strong Prognostic Implications in NK/T Cell Lymphoma

(2011) J. H. Paik et al.   CLINICAL CANCER RESEARCH

Clinical Significance of miR-146a in Gastric Cancer Cases

(2011) R. Kogo et al.   CLINICAL CANCER RESEARCH

MicroRNAs in Thyroid Cancer

(2011) Albert de la Chapelle et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

miR-146ais a significant brake on autoimmunity, myeloproliferation, and cancer in mice

(2011) Mark P. Boldin et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Deregulation of microRNAs in myelodysplastic syndrome

(2011) G W Rhyasen et al.   LEUKEMIA

MicroRNA-146a Inhibits Glioma Development by Targeting Notch1

(2011) J. Mei et al.   MOLECULAR AND CELLULAR BIOLOGY

NF- B dysregulation in microRNA-146a-deficient mice drives the development of myeloid malignancies

(2011) J. L. Zhao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Expression profiling of cytogenetically normal acute myeloid leukemia identifies MicroRNAs that target genes involved in monocytic differentiation

(2010) Mark Lutherborrow et al.   AMERICAN JOURNAL OF HEMATOLOGY

Advances in the 5q- syndrome

(2010) J. Boultwood et al.   BLOOD

MicroRNA expression in maturing murine megakaryocytes

(2010) J. B. Opalinska et al.   BLOOD

Genome-wide identification of human microRNAs located in leukemia-associated genomic alterations

(2010) D. T. Starczynowski et al.   BLOOD

miR-146a Suppresses Invasion of Pancreatic Cancer Cells

(2010) Y. Li et al.   CANCER RESEARCH

Function of miR-146a in Controlling Treg Cell-Mediated Regulation of Th1 Responses

(2010) Li-Fan Lu et al.   CELL

miR-146a and Krüppel-like factor 4 form a feedback loop to participate in vascular smooth muscle cell proliferation

(2010) Shao-guang Sun et al.   EMBO REPORTS

MicroRNA-146a disrupts hematopoietic differentiation and survival

(2010) Daniel T. Starczynowski et al.   EXPERIMENTAL HEMATOLOGY

CCL8/MCP-2 is a target for mir-146a in HIV-1-infected human microglial cells

(2010) Slava Rom et al.   FASEB JOURNAL

Micro-RNA response to imatinib mesylate in patients with chronic myeloid leukemia

(2010) S. Flamant et al.   HAEMATOLOGICA

Targeting Smad4 links microRNA-146a to the TGF-β pathway during retinoid acid induction in acute promyelocytic leukemia cell line

(2010) Hua Zhong et al.   INTERNATIONAL JOURNAL OF HEMATOLOGY

Nuclear Factor-κB Contributes to Anaplastic Thyroid Carcinomas through Up-Regulation of miR-146a

(2010) Francesco Pacifico et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Mechanistic Role of MicroRNA-146a in Endotoxin-Induced Differential Cross-Regulation of TLR Signaling

(2010) M. A. Nahid et al.   JOURNAL OF IMMUNOLOGY

miR-146a Is Differentially Expressed by Myeloid Dendritic Cell Subsets and Desensitizes Cells to TLR2-Dependent Activation

(2010) J. Jurkin et al.   JOURNAL OF IMMUNOLOGY

Up-regulated microRNA-146a negatively modulate Helicobacter pylori-induced inflammatory response in human gastric epithelial cells

(2010) Zhen Liu et al.   MICROBES AND INFECTION

MicroRNA-146a and Human Disease

(2010) L. Li et al.   SCANDINAVIAN JOURNAL OF IMMUNOLOGY

Karyotype-specific microRNA signature in chronic lymphocytic leukemia

(2009) R. Visone et al.   BLOOD

An emerging player in the adaptive immune response: microRNA-146a is a modulator of IL-2 expression and activation-induced cell death in T lymphocytes

(2009) G. Curtale et al.   BLOOD

Breast Cancer Metastasis Suppressor 1 Up-regulates miR-146, Which Suppresses Breast Cancer Metastasis

(2009) Douglas R. Hurst et al.   CANCER RESEARCH

MicroRNA-146a Feedback Inhibits RIG-I-Dependent Type I IFN Production in Macrophages by Targeting TRAF6, IRAK1, and IRAK2

(2009) J. Hou et al.   JOURNAL OF IMMUNOLOGY

Identification of miR-145 and miR-146a as mediators of the 5q– syndrome phenotype

(2009) Daniel T Starczynowski et al.   NATURE MEDICINE

Kaposi's sarcoma-associated herpesvirus-encoded viral FLICE inhibitory protein (vFLIP) K13 suppresses CXCR4 expression by upregulating miR-146a

(2009) V Punj et al.   ONCOGENE

Polymorphic mature microRNAs from passenger strand of pre-miR-146a contribute to thyroid cancer

(2009) K. Jazdzewski et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

p53 represses c-Myc through induction of the tumor suppressor miR-145

(2009) M. Sachdeva et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

MicroRNA signatures associated with cytogenetics and prognosis in acute myeloid leukemia

(2008) R. Garzon et al.   BLOOD

A three-step pathway comprising PLZF/miR-146a/CXCR4 controls megakaryopoiesis

(2008) Catherine Labbaye et al.   NATURE CELL BIOLOGY

Expression of microRNA-146 suppresses NF-κB activity with reduction of metastatic potential in breast cancer cells

(2008) D Bhaumik et al.   ONCOGENE

Aberrant Expression of Oncogenic and Tumor-Suppressive MicroRNAs in Cervical Cancer Is Required for Cancer Cell Growth

(2008) Xiaohong Wang et al.   PLoS One

Common SNP in pre-miR-146a decreases mature miR expression and predisposes to papillary thyroid carcinoma

(2008) K. Jazdzewski et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

MicroRNA miR-146a and further oncogenesis-related cellular microRNAs are dysregulated in HTLV-1-transformed T lymphocytes

(2008) Klemens Pichler et al.   Retrovirology

Loss of mir-146a function in hormone-refractory prostate cancer

(2008) S.-L. Lin et al.   RNA