Structural and dynamic determinants of type I interferon receptor assembly and their functional interpretation

Interferons as biomarkers and effectors: lessons learned from animal models

(2012) Cassandra M Berry et al.   Biomarkers in Medicine

Ubiquitination-mediated regulation of interferon responses

(2012) Serge Y. Fuchs   GROWTH FACTORS

The JAK-STAT Pathway at Twenty

(2012) George R. Stark et al.   IMMUNITY

Endogenous, or therapeutically induced, type I interferon responses differentially modulate Th1/Th17-mediated autoimmunity in the CNS

(2012) Ulrich Kalinke et al.   IMMUNOLOGY AND CELL BIOLOGY

The interferons and their receptors-distribution and regulation

(2012) Nicole A de Weerd et al.   IMMUNOLOGY AND CELL BIOLOGY

Membrane mechanisms for signal transduction: The coupling of the meso-scale raft domains to membrane-skeleton-induced compartments and dynamic protein complexes

(2012) Akihiro Kusumi et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

The WSXWS Motif in Cytokine Receptors Is a Molecular Switch Involved in Receptor Activation: Insight from Structures of the Prolactin Receptor

(2012) Robert Dagil et al.   STRUCTURE

Structural variants of IFN  preferentially promote antiviral functions

(2011) N. Vazquez et al.   BLOOD

Structural Linkage between Ligand Discrimination and Receptor Activation by Type I Interferons

(2011) Christoph Thomas et al.   CELL

Binding and activity of all human alpha interferon subtypes

(2011) Thomas B. Lavoie et al.   CYTOKINE

Beta Interferon Suppresses the Development of Experimental Cerebral Malaria

(2011) Craig N. Morrell et al.   INFECTION AND IMMUNITY

Suppressor of Cytokine Signaling (SOCS) 1 Inhibits Type I Interferon (IFN) Signaling via the Interferon α Receptor (IFNAR1)-associated Tyrosine Kinase Tyk2

(2011) Rebecca A. R. Piganis et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Evolutionary genetic dissection of human interferons

(2011) Jérémy Manry et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Interferon: Current Status and Future Prospects in Cancer Therapy

(2011) Ben X. Wang et al.   JOURNAL OF INTERFERON AND CYTOKINE RESEARCH

Stochastic Receptor Expression Determines Cell Fate upon Interferon Treatment

(2011) D. Levin et al.   MOLECULAR AND CELLULAR BIOLOGY

A diverse range of gene products are effectors of the type I interferon antiviral response

(2011) John W. Schoggins et al.   NATURE

USP18-Based Negative Feedback Control Is Induced by Type I and Type III Interferons and Specifically Inactivates Interferon α Response

(2011) Véronique François-Newton et al.   PLoS One

Interferon-stimulated genes and their antiviral effector functions

(2011) John W Schoggins et al.   Current Opinion in Virology

Self-Controlled Monofunctionalization of Quantum Dots for Multiplexed Protein Tracking in Live Cells

(2010) Changjiang You et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

NMR Mapping of the IFNAR1-EC Binding Site on IFNα2 Reveals Allosteric Changes in the IFNAR2-EC Binding Site

(2010) Sabine Ruth Akabayov et al.   BIOCHEMISTRY

The differential activity of interferon-α subtypes is consistent among distinct target genes and cell types

(2010) Herwig P. Moll et al.   CYTOKINE

Molecular basis of cytokine receptor activation

(2010) Angel F Lopez et al.   IUBMB LIFE

Major Differences in the Responses of Primary Human Leukocyte Subsets to IFN- 

(2010) A. H. H. van Boxel-Dezaire et al.   JOURNAL OF IMMUNOLOGY

Differential Gene Expression and Translational Approaches to Identify Biomarkers of Interferon Beta Activity in Multiple Sclerosis

(2010) Ed Croze   JOURNAL OF INTERFERON AND CYTOKINE RESEARCH

Interferon-Stimulated Gene 15 and the Protein ISGylation System

(2010) Dongxian Zhang et al.   JOURNAL OF INTERFERON AND CYTOKINE RESEARCH

Crystal Structure of Human Interferon-λ1 in Complex with Its High-Affinity Receptor Interferon-λR1

(2010) Zachary J. Miknis et al.   JOURNAL OF MOLECULAR BIOLOGY

Ligand-Stimulated Downregulation of the Alpha Interferon Receptor: Role of Protein Kinase D2

(2010) H. Zheng et al.   MOLECULAR AND CELLULAR BIOLOGY

Creation of Interferon-α8 Mutants with Amino Acid Substitutions Against Interferon-α Receptor-2 Binding Sites Using Phage Display System and Evaluation of Their Biologic Properties

(2009) Kouzo Yamamoto et al.   JOURNAL OF INTERFERON AND CYTOKINE RESEARCH

Biochemical Monitoring of the Early Endocytic Traffic of the Type I Interferon Receptor

(2009) Béatrice Payelle-Brogard et al.   JOURNAL OF INTERFERON AND CYTOKINE RESEARCH

Receptor Density Is Key to the Alpha2/Beta Interferon Differential Activities

(2009) I. Moraga et al.   MOLECULAR AND CELLULAR BIOLOGY

Unphosphorylated STAT1 prolongs the expression of interferon-induced immune regulatory genes

(2009) H. Cheon et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Enhanced anti-HCV activity of interferon alpha 17 subtype

(2009) Aurelie Dubois et al.   Virology Journal

Mutation of the IFNAR-1 Receptor Binding Site of Human IFN-α2 Generates Type I IFN Competitive Antagonists†

(2008) Manjing Pan et al.   BIOCHEMISTRY

Probing Protein Conformations by in Situ Non-Covalent Fluorescence Labeling

(2008) Jennifer Julia Strunk et al.   BIOCONJUGATE CHEMISTRY

Crystal structure of the IL-22/IL-22R1 complex and its implications for the IL-22 signaling mechanism

(2008) Lucas Bleicher et al.   FEBS LETTERS

Basal Ubiquitin-independent Internalization of Interferon α Receptor Is Prevented by Tyk2-mediated Masking of a Linear Endocytic Motif

(2008) K. G. Suresh Kumar et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Stability of the Ternary Interferon-Receptor Complex Rather than the Affinity to the Individual Subunits Dictates Differential Biological Activities

(2008) Eyal Kalie et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Ligand Binding Induces a Conformational Change in ifnar1 that Is Propagated to Its Membrane-Proximal Domain

(2008) Jennifer Julia Strunk et al.   JOURNAL OF MOLECULAR BIOLOGY

INTERFEROME: the database of interferon regulated genes

(2008) Shamith A. Samarajiwa et al.   NUCLEIC ACIDS RESEARCH

Structure of IL-22 Bound to Its High-Affinity IL-22R1 Chain

(2008) Brandi C. Jones et al.   STRUCTURE

Interferons and viruses: an interplay between induction, signalling, antiviral responses and virus countermeasures

(2007) R. E. Randall et al.   JOURNAL OF GENERAL VIROLOGY

The EM Structure of a Type I Interferon–Receptor Complex Reveals a Novel Mechanism for Cytokine Signaling

(2007) Zongli Li et al.   JOURNAL OF MOLECULAR BIOLOGY