Ubiquitination-mediated regulation of interferon responses

Bcr-abl signals to desensitize chronic myeloid leukemia cells to IFN  via accelerating the degradation of its receptor

(2011) S. Bhattacharya et al.   BLOOD

Vascular endothelial growth factor-induced elimination of the type 1 interferon receptor is required for efficient angiogenesis

(2011) H. Zheng et al.   BLOOD

Ubiquitination of E3 ligases: self-regulation of the ubiquitin system via proteolytic and non-proteolytic mechanisms

(2011) P de Bie et al.   CELL DEATH AND DIFFERENTIATION

Suppressor of Cytokine Signaling (SOCS) 1 Inhibits Type I Interferon (IFN) Signaling via the Interferon α Receptor (IFNAR1)-associated Tyrosine Kinase Tyk2

(2011) Rebecca A. R. Piganis et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Tyrosine Phosphorylation of Protein Kinase D2 Mediates Ligand-inducible Elimination of the Type 1 Interferon Receptor

(2011) Hui Zheng et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Role of Nuclear Factor κB in the Interferon Response

(2011) Lawrence M. Pfeffer   JOURNAL OF INTERFERON AND CYTOKINE RESEARCH

Kaposi's Sarcoma-Associated Herpesvirus Viral Interferon Regulatory Factor 3 Inhibits Gamma Interferon and Major Histocompatibility Complex Class II Expression

(2011) K. Schmidt et al.   JOURNAL OF VIROLOGY

Inflammatory signaling compromises cell responses to interferon alpha

(2011) W-C HuangFu et al.   ONCOGENE

PDlim2 Selectively Interacts with the PDZ Binding Motif of Highly Pathogenic Avian H5N1 Influenza A Virus NS1

(2011) Jia Yu et al.   PLoS One

Human Metapneumovirus Inhibits IFN-β Signaling by Downregulating Jak1 and Tyk2 Cellular Levels

(2011) Junping Ren et al.   PLoS One

HRD1 and UBE2J1 target misfolded MHC class I heavy chains for endoplasmic reticulum-associated degradation

(2011) Marian L. Burr et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Tetherin is a key effector of the antiretroviral activity of type I interferon in vitro and in vivo

(2011) R. A. Liberatore et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

PDLIM2 Inhibits T Helper 17 Cell Development and Granulomatous Inflammation Through Degradation of STAT3

(2011) T. Tanaka et al.   Science Signaling

Mechanism of HCV's resistance to IFN-α in cell culture involves expression of functional IFN-α receptor 1

(2011) Sibnarayan Datta et al.   Virology Journal

Mutation of the elongin C binding domain of human respiratory syncytial virus non-structural protein 1 (NS1) results in degradation of NS1 and attenuation of the virus

(2011) Claire P Straub et al.   Virology Journal

What Has the Study of the K3 and K5 Viral Ubiquitin E3 Ligases Taught Us about Ubiquitin-Mediated Receptor Regulation?

(2011) Jessica M. Boname et al.   Viruses-Basel

Identification of DNA-Damage DNA-Binding Protein 1 as a Conditional Essential Factor for Cytomegalovirus Replication in Interferon-γ-Stimulated Cells

(2011) Mirko Trilling et al.   PLoS Pathogens

BST2/Tetherin Enhances Entry of Human Cytomegalovirus

(2011) Kasinath Viswanathan et al.   PLoS Pathogens

Pathogen Recognition Receptor Signaling Accelerates Phosphorylation-Dependent Degradation of IFNAR1

(2011) Juan Qian et al.   PLoS Pathogens

Notch-induced Asb2 expression promotes protein ubiquitination by forming non-canonical E3 ligase complexes

(2010) Lei Nie et al.   CELL RESEARCH

Ubiquitin networks in cancer

(2010) Vladimir Kirkin et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

Viral hijacking of the host ubiquitin system to evade interferon responses

(2010) Kasinath Viswanathan et al.   CURRENT OPINION IN MICROBIOLOGY

Osteopontin and Protein Kinase C Regulate PDLIM2 Activation and STAT1 Ubiquitination in LPS-treated Murine Macrophages

(2010) Hongtao Guo et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Interferon-Lambda: A New Addition to an Old Family

(2010) Raymond P. Donnelly et al.   JOURNAL OF INTERFERON AND CYTOKINE RESEARCH

Interferon-Stimulated Gene 15 and the Protein ISGylation System

(2010) Dongxian Zhang et al.   JOURNAL OF INTERFERON AND CYTOKINE RESEARCH

Ligand-Stimulated Downregulation of the Alpha Interferon Receptor: Role of Protein Kinase D2

(2010) H. Zheng et al.   MOLECULAR AND CELLULAR BIOLOGY

SH2 Modified STAT1 Induces HLA-I Expression and Improves IFN-γ Signaling in IFN-α Resistant HCV Replicon Cells

(2010) Bret Poat et al.   PLoS One

The RING-CH Ligase K5 Antagonizes Restriction of KSHV and HIV-1 Particle Release by Mediating Ubiquitin-Dependent Endosomal Degradation of Tetherin

(2010) Claire Pardieu et al.   PLoS Pathogens

The Great Escape: Viral Strategies to Counter BST-2/Tetherin

(2010) Janet L. Douglas et al.   PLoS Pathogens

Virus-Induced Unfolded Protein Response Attenuates Antiviral Defenses via Phosphorylation-Dependent Degradation of the Type I Interferon Receptor

(2009) Jianghuai Liu et al.   Cell Host & Microbe

Inducible Priming Phosphorylation Promotes Ligand-independent Degradation of the IFNAR1 Chain of Type I Interferon Receptor

(2009) Sabyasachi Bhattacharya et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Paramyxovirus Disruption of Interferon Signal Transduction: STATus Report

(2009) Aparna Ramachandran et al.   JOURNAL OF INTERFERON AND CYTOKINE RESEARCH

Biochemical Monitoring of the Early Endocytic Traffic of the Type I Interferon Receptor

(2009) Béatrice Payelle-Brogard et al.   JOURNAL OF INTERFERON AND CYTOKINE RESEARCH

NS5 of Dengue Virus Mediates STAT2 Binding and Degradation

(2009) J. Ashour et al.   JOURNAL OF VIROLOGY

A Point Mutation, E95D, in the Mumps Virus V Protein Disengages STAT3 Targeting from STAT1 Targeting

(2009) M. Puri et al.   JOURNAL OF VIROLOGY

Molecular Mechanism of BST2/Tetherin Downregulation by K5/MIR2 of Kaposi's Sarcoma-Associated Herpesvirus

(2009) M. Mansouri et al.   JOURNAL OF VIROLOGY

The EBV-encoded latent membrane proteins, LMP2A and LMP2B, limit the actions of interferon by targeting interferon receptors for degradation

(2009) K M Shah et al.   ONCOGENE

The SARS Coronavirus 3a Protein Causes Endoplasmic Reticulum Stress and Induces Ligand-Independent Downregulation of the Type 1 Interferon Receptor

(2009) Rinki Minakshi et al.   PLoS One

Efficient Internalization of MHC I Requires Lysine-11 and Lysine-63 Mixed Linkage Polyubiquitin Chains

(2009) Jessica M. Boname et al.   TRAFFIC

HIV-1 Vpu Neutralizes the Antiviral Factor Tetherin/BST-2 by Binding It and Directing Its Beta-TrCP2-Dependent Degradation

(2009) Bastien Mangeat et al.   PLoS Pathogens

Vpu Antagonizes BST-2–Mediated Restriction of HIV-1 Release via β-TrCP and Endo-Lysosomal Trafficking

(2009) Richard S. Mitchell et al.   PLoS Pathogens

Roles of ubiquitination in pattern-recognition receptors and type I interferon receptor signaling

(2008) Annie Bibeau-Poirier et al.   CYTOKINE

Negative regulation of cytoplasmic RNA-mediated antiviral signaling

(2008) Akihiko Komuro et al.   CYTOKINE

The Role of TRAF2 Binding to the Type I Interferon Receptor in Alternative NFκB Activation and Antiviral Response

(2008) Chuan He Yang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Basal Ubiquitin-independent Internalization of Interferon α Receptor Is Prevented by Tyk2-mediated Masking of a Linear Endocytic Motif

(2008) K. G. Suresh Kumar et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

ERK and the F-box Protein βTRCP Target STAT1 for Degradation

(2008) Surinder M. Soond et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Human cytomegalovirus interferes with signal transducer and activator of transcription (STAT) 2 protein stability and tyrosine phosphorylation

(2008) V. T. K. Le et al.   JOURNAL OF GENERAL VIROLOGY

HIV-1 Vif, APOBEC, and Intrinsic Immunity

(2008) Ritu Goila-Gaur et al.   Retrovirology

The ubiquitin-mediated degradation of Jak1 modulates osteoclastogenesis by limiting interferon- induced inhibitory signaling

(2007) Y. Lee et al.   BLOOD