Pathogenesis of adult-onset Still’s disease: new insights from the juvenile counterpart

Adult-onset Still's disease

(2014) Mathieu Gerfaud-Valentin et al.   AUTOIMMUNITY REVIEWS

Life-threatening complications of adult-onset Still’s disease

(2014) Petros Efthimiou et al.   CLINICAL RHEUMATOLOGY

Adult-Onset Still Disease

(2014) Mathieu Gerfaud-Valentin et al.   MEDICINE

Improvement of reduced serum cartilage oligomeric matrix protein levels in systemic juvenile idiopathic arthritis patients treated with the anti-interleukin-6 receptor monoclonal antibody tocilizumab

(2014) Shoko Nakajima et al.   Modern Rheumatology

A157: Macrophage Activation Syndrome-like Illness Due to an Activating Mutation in NLRC4

(2014) Scott Canna et al.   Arthritis & Rheumatology

Editorial: Interferon-γ: Friend or Foe in Systemic Juvenile Idiopathic Arthritis and Adult-Onset Still's Disease?

(2014) Scott W. Canna   Arthritis & Rheumatology

The Hyperferritinemic Syndrome: macrophage activation syndrome, Still’s disease, septic shock and catastrophic antiphospholipid syndrome

(2013) Cristina Rosário et al.   BMC Medicine

Tocilizumab for the treatment of adult-onset Still’s disease: results from a case series

(2013) Paola Cipriani et al.   CLINICAL RHEUMATOLOGY

Inflammasome Activation by Altered Proteostasis

(2013) Jin Na Shin et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

How should we approach classification of autoinflammatory diseases?

(2013) Gilles Grateau et al.   Nature Reviews Rheumatology

Adult-onset Still’s disease and pregnancy: about ten cases and review of the literature

(2013) M. Gerfaud-Valentin et al.   RHEUMATOLOGY INTERNATIONAL

Clinical Manifestations of Adult-Onset Still's Disease Presenting With Erosive Arthritis: Association With Low Levels of Ferritin and Interleukin-18

(2013) Hisae Ichida et al.   ARTHRITIS CARE & RESEARCH

Involvement of TLR7 MyD88-dependent signaling pathway in the pathogenesis of adult-onset Still's disease

(2013) Der-Yuan Chen et al.   ARTHRITIS RESEARCH & THERAPY

A genetic role for macrophage migration inhibitory factor (MIF) in adult-onset Still's disease

(2013) Fang-Fang Wang et al.   ARTHRITIS RESEARCH & THERAPY

Natural killer T cell deficiency in active adult-onset Still's disease: Correlation of deficiency of natural killer T cells with dysfunction of natural killer cells

(2012) Sung-Ji Lee et al.   ARTHRITIS AND RHEUMATISM

Targeting interleukin-1β in CAPS (cryopyrin-associated periodic) syndromes

(2012) Isabelle Koné-Paut et al.   AUTOIMMUNITY REVIEWS

Autoinflammatory syndromes and cellular responses to stress: pathophysiology, diagnosis and new treatment perspectives

(2012) Sinisa Savic et al.   BEST PRACTICE & RESEARCH IN CLINICAL RHEUMATOLOGY

Transient impairment of NK cell function in an infant born to a mother with adult-onset Still's disease: Perinatal effect of maternal IL-18

(2012) Masaki Shimizu et al.   CLINICAL IMMUNOLOGY

Distinct subsets of patients with systemic juvenile idiopathic arthritis based on their cytokine profiles

(2012) Masaki Shimizu et al.   CYTOKINE

Macrophage activation syndrome as part of systemic juvenile idiopathic arthritis: diagnosis, genetics, pathophysiology and treatment

(2012) A Ravelli et al.   GENES AND IMMUNITY

Natural Killer Cell Cytolytic Function in Korean Patients with Adult-onset Still's Disease

(2012) J. H. PARK et al.   JOURNAL OF RHEUMATOLOGY

Still’s disease and the mitochondrion: The other face of an old friend?

(2012) François Hayem et al.   MEDICAL HYPOTHESES

Randomized Trial of Tocilizumab in Systemic Juvenile Idiopathic Arthritis

(2012) Fabrizio De Benedetti et al.   NEW ENGLAND JOURNAL OF MEDICINE

Neutrophil CD64 is upregulated in patients with active adult-onset Still's disease

(2012) A Komiya et al.   SCANDINAVIAN JOURNAL OF RHEUMATOLOGY

Evanescent and Persistent Pruritic Eruptions of Adult-Onset Still Disease: A Clinical and Pathologic Study of 36 Patients

(2012) Julia Yu-Yun Lee et al.   SEMINARS IN ARTHRITIS AND RHEUMATISM

ER stress activates the NLRP3 inflammasome via an UPR-independent pathway

(2012) P Menu et al.   Cell Death & Disease

Interleukin-6 plays an essential role in hypoxia-inducible factor 2α-induced experimental osteoarthritic cartilage destruction in mice

(2011) Je-Hwang Ryu et al.   ARTHRITIS AND RHEUMATISM

The pathogenesis of oligoarticular/polyarticular vs systemic juvenile idiopathic arthritis

(2011) Yu-Tsan Lin et al.   AUTOIMMUNITY REVIEWS

Alternative activation in systemic juvenile idiopathic arthritis monocytes

(2011) Claudia Macaubas et al.   CLINICAL IMMUNOLOGY

The expanding spectrum of hemophagocytic lymphohistiocytosis

(2011) Alexandra H. Filipovich   Current Opinion in Allergy and Clinical Immunology

Association of IRF5 Polymorphisms with Susceptibility to Macrophage Activation Syndrome in Patients with Juvenile Idiopathic Arthritis

(2011) M. YANAGIMACHI et al.   JOURNAL OF RHEUMATOLOGY

Pathogenesis of systemic juvenile idiopathic arthritis: some answers, more questions

(2011) Elizabeth D. Mellins et al.   Nature Reviews Rheumatology

Anakinra as first-line disease-modifying therapy in systemic juvenile idiopathic arthritis: Report of forty-six patients from an international multicenter series

(2010) Peter A. Nigrovic et al.   ARTHRITIS AND RHEUMATISM

Autoinflammatory Disease Reloaded: A Clinical Perspective

(2010) Daniel L. Kastner et al.   CELL

Monocytes are resistant to apoptosis in systemic juvenile idiopathic arthritis

(2010) Shivani Srivastava et al.   CLINICAL IMMUNOLOGY

The associations of circulating CD4+CD25highregulatory T cells and TGF-β with disease activity and clinical course in patients with adult-onset Still's disease

(2010) Der-Yuan Chen et al.   CONNECTIVE TISSUE RESEARCH

Potential role of Th17 cells in the pathogenesis of adult-onset Still's disease

(2010) D.-Y. Chen et al.   RHEUMATOLOGY

Distinct cytokine profiles of systemic-onset juvenile idiopathic arthritis-associated macrophage activation syndrome with particular emphasis on the role of interleukin-18 in its pathogenesis

(2010) M. Shimizu et al.   RHEUMATOLOGY

Tocilizumab in refractory adult Still's disease

(2010) Xavier Puéchal et al.   ARTHRITIS CARE & RESEARCH

Lymph node IL-18 expression in adult-onset Still's disease

(2009) P Conigliaro et al.   ANNALS OF THE RHEUMATIC DISEASES

Horror Autoinflammaticus: The Molecular Pathophysiology of Autoinflammatory Disease

(2009) Seth L. Masters et al.   Annual Review of Immunology

Subtype-specific peripheral blood gene expression profiles in recent-onset juvenile idiopathic arthritis

(2009) Michael G. Barnes et al.   ARTHRITIS AND RHEUMATISM

The myeloid-related proteins 8 and 14 complex, a novel ligand of toll-like receptor 4, and interleukin-1β form a positive feedback mechanism in systemic-onset juvenile idiopathic arthritis

(2009) Michael Frosch et al.   ARTHRITIS AND RHEUMATISM

Defective phosphorylation of interleukin-18 receptor β causes impaired natural killer cell function in systemic-onset juvenile idiopathic arthritis

(2009) Wilco de Jager et al.   ARTHRITIS AND RHEUMATISM

Frequency, clinical features and prognosis of cutaneous manifestations in adult patients with reactive haemophagocytic syndrome

(2009) L. Fardet et al.   BRITISH JOURNAL OF DERMATOLOGY

Distribution of circulating cells in systemic juvenile idiopathic arthritis across disease activity states

(2009) Claudia Macaubas et al.   CLINICAL IMMUNOLOGY

A Mutation in the Nlrp3 Gene Causing Inflammasome Hyperactivation Potentiates Th17 Cell-Dominant Immune Responses

(2009) Guangxun Meng et al.   IMMUNITY

Therapy of autoinflammatory syndromes

(2009) Hal M. Hoffman   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Autoinflammation: The prominent role of IL-1 in monogenic autoinflammatory diseases and implications for common illnesses

(2009) Raphaela Goldbach-Mansky et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Mutations in the perforin gene can be linked to macrophage activation syndrome in patients with systemic onset juvenile idiopathic arthritis

(2009) Sebastiaan J. Vastert et al.   RHEUMATOLOGY

The pattern of response to anti–interleukin-1 treatment distinguishes two subsets of patients with systemic-onset juvenile idiopathic arthritis

(2008) Marco Gattorno et al.   ARTHRITIS AND RHEUMATISM

Macrophage activation syndrome in patients with systemic juvenile idiopathic arthritis is associated with MUNC13-4 polymorphisms

(2008) Kejian Zhang et al.   ARTHRITIS AND RHEUMATISM

Comprehensive association study of genetic variants in the IL-1 gene family in systemic juvenile idiopathic arthritis

(2008) C J W Stock et al.   GENES AND IMMUNITY

Ferritin functions as a proinflammatory cytokine via iron-independent protein kinase C zeta/nuclear factor kappaB-regulated signaling in rat hepatic stellate cells

(2008) Richard G. Ruddell et al.   HEPATOLOGY