Article
Nutrition & Dietetics
Christina M. Fischer, Ming Zhang, Maya R. Sternberg, Maria E. Jefferds, Ralph D. Whitehead, Zuguo Mei, Naveen Paudyal, Nira Joshi, Kedar R. Parajuli, Debendra P. Adhikari, Donna J. LaVoie, Christine M. Pfeiffer
Summary: Using samples from the Nepal survey, the VitMin ELISA assays produced mostly comparable results to the Roche reference-type assays for Fer, CRP and AGP. However, the lack of standardization in sTfR assays led to a significant systematic difference.
JOURNAL OF NUTRITION
(2022)
Article
Multidisciplinary Sciences
Allison L. Fisher, Veena Sangkhae, Kamila Balusikova, Nicolaos J. Palaskas, Tomas Ganz, Elizabeta Nemeth
Summary: Iron is essential for embryo and placental development and maternal health during pregnancy, but excess maternal iron can lead to adverse embryo outcomes in pregnancies with underlying systemic inflammation, as demonstrated in a study using mouse models.
NATURE COMMUNICATIONS
(2021)
Article
Nutrition & Dietetics
Tsitsi Letwin Chimhashu, Hans Verhoef, Elizabeth A. Symington, Lizelle Zandberg, Jeannine Baumgartner, Linda Malan, Cornelius Marius Smuts, Edith J. M. Feskens, Alida Melse-Boonstra
Summary: This study compared the agreement between the 7-Plex and s-ELISA methods for measuring five analytes. The results showed strong correlations between the two methods for CRP and ferritin, but poor agreement for the other analytes. Discrepancies between the methods increased as serum concentrations rose. The 7-Plex 1.0 has potential as a research and surveillance tool in low-resource laboratories, but further optimization and validation are needed to establish its interchangeability with other methods.
BRITISH JOURNAL OF NUTRITION
(2023)
Article
Public, Environmental & Occupational Health
Minerva Montero-Diaz, Cristina Chavez-Chong, Ernesto Rodriguez-Martinez, Gisela M. Pita-Rodriguez, Brenda Lambert-Lamazares, Beatriz Basabe-Tuero, Karen Alfonso-Sague
Summary: This study assessed the utility and relevance of quadratic regression and quantile quadratic regression models in adjusting ferritin concentration in the presence of inflammation. The results showed that the prevalence of iron deficiency increased when using the quadratic regression correction model, and the increase was more pronounced when using the quantile regression correction model. The use of these models is a complementary strategy in adjusting ferritin for inflammation.
Article
Biochemistry & Molecular Biology
Aparajita Sen, Arti Nigam, Meenakshi Vachher
Summary: The COVID-19 pandemic has had devastating impacts on people's lives globally. Timely diagnosis and assessment of disease severity are crucial. The search for reliable biomarkers that can detect the disease early is important for clinical management and resource allocation.
INTERNATIONAL JOURNAL OF PEPTIDE RESEARCH AND THERAPEUTICS
(2022)
Article
Medicine, General & Internal
Virendra C. Patil, Shivamsh R. Kasireddy, Hrutu N. Gada, Harsha Patil
Summary: The study evaluated laboratory parameters in COVID-19 patients and compared patients presenting in 2020 to 2021. The findings indicated a positive correlation between various inflammatory markers and disease severity, supporting their use for monitoring disease progression. In 2021, there was a trend of younger population being more frequently infected with COVID-19.
JOURNAL OF KRISHNA INSTITUTE OF MEDICAL SCIENCES UNIVERSITY
(2021)
Review
Ophthalmology
Melis Kabaalioglu Guner, Ankur Mehra, Wendy M. Smith
Summary: Scleritis is a severe ocular inflammation associated with systemic diseases, timely diagnosis and treatment are crucial. Traditional treatment methods are being replaced by novel diagnostic and treatment modalities to improve patient outcomes.
EXPERT REVIEW OF OPHTHALMOLOGY
(2021)
Article
Biochemical Research Methods
Amna Klich, Catherine Mercier, Laurent Gerfault, Pierre Grangeat, Corinne Beaulieu, Elodie Degout-Charmette, Tanguy Fortin, Pierre Mahe, Jean-Francois Giovannelli, Jean-Philippe Charrier, Audrey Giremus, Delphine Maucort-Boulch, Pascal Roy
BMC BIOINFORMATICS
(2018)
Letter
Dermatology
Amelie Boespflug, Sebastien Debarbieux, Lauriane Depaepe, Brigitte Chouvet, Delphine Maucort-Boulch, Stephane Dalle, Brigitte Balme, Luc Thomas
JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY
(2019)
Article
Oncology
Julien Peron, Alexandre Lambert, Stephane Munier, Brice Ozenne, Joris Giai, Pascal Roy, Stephane Dalle, Abigirl Machingura, Delphine Maucort-Boulch, Marc Buyse
JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE
(2019)
Article
Gastroenterology & Hepatology
Julien Peron, Joris Giai, Delphine Maucort-Boulch, Marc Buyse
Article
Urology & Nephrology
B. Gabay, D. Maucort-Boulch, A. Ruffion, M. C. Scheiber Nogueira, J. E. Terrier
PROGRES EN UROLOGIE
(2019)
Article
Oncology
Mathilde Berger, Mona Amini-Adle, Delphine Maucort-Boulch, Philip Robinson, Luc Thomas, Stephane Dalle, Pierre-Yves Courand
Review
Multidisciplinary Sciences
Theo Delbove, Francois Gueyffier, Laurent Juillard, Emilie Kalbacher, Delphine Maucort-Boulch, Patrice Nony, Brigitte Grosgogeat, Kerstin Gritsch
Summary: The study found that periodontal treatment seems to improve the condition of chronic kidney disease patients, especially by reducing systemic inflammation. Further RCTs are needed to confirm the results and specifically assess the influence of different types of periodontal treatment on CKD patients. Early management of periodontitis is extremely important for patients with impaired renal function and can prevent further tooth loss and malnutrition.
Article
Mathematical & Computational Biology
Julien Peron, Maryam Idlhaj, Delphine Maucort-Boulch, Joris Giai, Pascal Roy, Laurence Collette, Marc Buyse, Brice Ozenne
Summary: Generalized pairwise comparisons are used in randomized clinical trials to analyze multiple prioritized outcomes simultaneously. A correction method has been proposed to estimate the contribution of uninformative pairs based on the average contribution of informative pairs. The correction does not affect the power or type-1 error of tests based on Delta, and is most useful when the proportion of censored observations is close to 70%.
BIOMETRICAL JOURNAL
(2021)
Article
Clinical Neurology
Salem Hannoun, Gabriel Kocevar, Pekes Codjia, Delphine Maucort-Boulch, Francois Cotton, Sandra Vukusic, Francoise Durand-Dubief, Dominique Sappey-Marinier
Summary: Longitudinal analysis of T1-weighted images in multiple sclerosis patients over 4 years showed no significant signal intensity increases in the dentate nuclei and subcortical gray matter structures with cumulative administration of the macrocyclic gadolinium-based contrast agent, gadoterate meglumine.
CLINICAL NEURORADIOLOGY
(2022)
Article
Oncology
Marie-Alix Mangin, Amelie Boespflug, Delphine Maucort Boulch, Charles-Herve Vacheron, Isabelle Carpentier, Luc Thomas, Stephane Dalle
Summary: In patients with metastatic melanoma, prior treatment with ICI followed by CC may lead to better clinical outcomes compared to prior treatment with MAPKi followed by CC. Further investigation is needed to confirm the potential benefits of CC in this setting.
Article
Medicine, General & Internal
Yvan Jamilloux, Nicolas Romain-Scelle, Muriel Rabilloud, Coralie Morel, Laurent Kodjikian, Delphine Maucort-Boulch, Philip Bielefeld, Pascal Seve
Summary: The study aimed to implement and validate a Bayesian belief network algorithm for the differential diagnosis of the most relevant causes of uveitis. The algorithm, based on simple epidemiological characteristics and anatomoclinical features of uveitis, achieved high accuracy in both the training and test datasets.
JOURNAL OF CLINICAL MEDICINE
(2021)
Article
Hematology
Estelle Bourbon, Delphine Maucort-Boulch, Juliette Fontaine, Claire Mauduit, Pierre Sesques, Violaine Safar, Emmanuelle Ferrant, Camille Golfier, Dana Ghergus, Lionel Karlin, Anne Lazareth, Fadhela Bouafia, Gian Matteo Pica, Frederique Orsini-Piocelle, Clement Rocher, Francois-Xavier Gros, Marie Parrens, Arthur Dony, Cedric Rossi, Herve Ghesquieres, Emmanuel Bachy, Alexandra Traverse-Glehen, Clementine Sarkozy
Summary: This retrospective study reported 70 cases of EBV(+) diffuse large B-cell lymphoma, with a median age of 68.5 years. Patients were mainly treated with immunochemotherapy or chemotherapy. Older age and HLH were associated with shorter PFS and OS.
Article
Oncology
V. Larbre, N. Romain-Scelle, P. Reymond, Y. Ladjouzi, C. Herledan, A. G. Caffin, A. Baudouin, M. Maire, D. Maucort-Boulch, F. Ranchon, C. Rioufol
Summary: This study aimed to assess the impact of the COVID-19 pandemic on treatment consumption and telemedicine development in outpatients receiving oral anti-cancer agents. The results showed that a portion of patients took medication or complementary and alternative medicine (CAM) for various reasons during lockdown. The habits of obtaining drugs from the pharmacy changed significantly, while other treatment habits did not. Most patients were satisfied with the telephone follow-up and willing to continue using telemedicine in future epidemic waves.
JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY
(2023)
Article
Mathematical & Computational Biology
Joris Giai, Delphine Maucort-Boulch, Brice Ozenne, Jean-Christophe Chiem, Marc Buyse, Julien Peron
Summary: This study assessed the impact of correlation between prioritized outcomes on the balance between benefit and risk in clinical trials. The results showed that correlations between outcomes lead to substantial but predictable modifications of Delta and its estimate, which should be taken into consideration when performing sample size estimations.
STATISTICS IN MEDICINE
(2021)
Article
Mathematical & Computational Biology
Catherine Mercier, Amna Klich, Caroline Truntzer, Vincent Picaud, Jean-Francois Giovannelli, Patrick Ducoroy, Pierre Grangeat, Delphine Maucort-Boulch, Pascal Roy
BIOMETRICAL JOURNAL
(2018)