Therapeutic potential of resveratrol in heart failure

Preclinical and clinical evidence for the role of resveratrol in the treatment of cardiovascular diseases

(2015) Beshay N.M. Zordoky et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Is AMPK the savior of the failing heart?

(2015) Ty T. Kim et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Resveratrol modulates the angiogenic response to exercise training in skeletal muscles of aged men

(2014) Lasse Gliemann et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Resveratrol improves muscle function but not oxidative capacity in young mdx mice

(2014) Bradley S. Gordon et al.   CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY

Heart Failure With Preserved Ejection Fraction

(2014) Kavita Sharma et al.   CIRCULATION RESEARCH

Resveratrol: review on therapeutic potential and recent advances in drug delivery

(2014) Rudra Pangeni et al.   Expert Opinion on Drug Delivery

Resveratrol, an activator of SIRT1, upregulates AMPK and improves cardiac function in heart failure

(2014) X.S. Gu et al.   GENETICS AND MOLECULAR RESEARCH

Exercise training, but not resveratrol, improves metabolic and inflammatory status in skeletal muscle of aged men

(2014) Jesper Olesen et al.   JOURNAL OF PHYSIOLOGY-LONDON

Resveratrol ameliorates cardiac dysfunction induced by pressure overload in rats via structural protection and modulation of Ca2+ cycling proteins

(2014) Qi Dong et al.   Journal of Translational Medicine

Experimental Studies of the Molecular Pathways Regulated by Exercise and Resveratrol in Heart, Skeletal Muscle and the Vasculature

(2014) Vernon Dolinsky et al.   MOLECULES

Protective effect of resveratrol against pressure overload-induced heart failure

(2014) Prakash K. Gupta et al.   Food Science & Nutrition

Both aerobic exercise and resveratrol supplementation attenuate doxorubicin-induced cardiac injury in mice

(2013) Vernon W. Dolinsky et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Resveratrol prevents hypertension and cardiac hypertrophy in hypertensive rats and mice

(2013) Vernon W. Dolinsky et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Optimization of trans-Resveratrol bioavailability for human therapy

(2013) Marie Josephe Amiot et al.   BIOCHIMIE

Characterization of a novel multifunctional resveratrol derivative for the treatment of atrial fibrillation

(2013) Istvan Baczko et al.   BRITISH JOURNAL OF PHARMACOLOGY

2013 ACCF/AHA Guideline for the Management of Heart Failure: Executive Summary

(2013) Clyde W. Yancy et al.   CIRCULATION

Resveratrol and Clinical Trials: The Crossroad from In Vitro Studies to Human Evidence

(2013) Joao Tomé-Carneiro et al.   CURRENT PHARMACEUTICAL DESIGN

Resveratrol Improves Vascular Function in Patients With Hypertension and Dyslipidemia by Modulating NO Metabolism

(2013) Albino Carrizzo et al.   HYPERTENSION

Muscle wasting in heart failure: An overview

(2013) Stephan von Haehling et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Calcium cycling proteins and heart failure: mechanisms and therapeutics

(2013) Andrew R. Marks   JOURNAL OF CLINICAL INVESTIGATION

Chronic resveratrol consumption improves brachial flow-mediated dilatation in healthy obese adults

(2013) Rachel H.X. Wong et al.   JOURNAL OF HYPERTENSION

Resveratrol blunts the positive effects of exercise training on cardiovascular health in aged men

(2013) Lasse Gliemann et al.   JOURNAL OF PHYSIOLOGY-LONDON

Resveratrol Protects against Physical Fatigue and Improves Exercise Performance in Mice

(2013) Ruei-Er Wu et al.   MOLECULES

Bioaccumulation of resveratrol metabolites in myocardial tissue is dose-time dependent and related to cardiac hemodynamics in diabetic rats

(2013) L. Bresciani et al.   NUTRITION METABOLISM AND CARDIOVASCULAR DISEASES

Sulfate Metabolites Provide an Intracellular Pool for Resveratrol Generation and Induce Autophagy with Senescence

(2013) K. R. Patel et al.   Science Translational Medicine

Heart Failure

(2013) Eugene Braunwald   JACC-Heart Failure

Resveratrol Reverses Remodeling in Hearts with Large, Old Myocardial Infarctions through Enhanced Autophagy-Activating AMP Kinase Pathway

(2012) Hiromitsu Kanamori et al.   AMERICAN JOURNAL OF PATHOLOGY

Resveratrol inhibits neointimal formation after arterial injury through an endothelial nitric oxide synthase-dependent mechanism

(2012) Danna M. Breen et al.   ATHEROSCLEROSIS

Resveratrol improves myocardial ischemia and ischemic heart failure in mice by antagonizing the detrimental effects of fractalkine*

(2012) Wanling Xuan et al.   CRITICAL CARE MEDICINE

Unraveling new mechanisms of exercise intolerance in chronic heart failure. Role of exercise training

(2012) Viviane M. Conraads et al.   HEART FAILURE REVIEWS

Metabolic and structural impairment of skeletal muscle in heart failure

(2012) Cynthia Zizola et al.   HEART FAILURE REVIEWS

Improvements in skeletal muscle strength and cardiac function induced by resveratrol during exercise training contribute to enhanced exercise performance in rats

(2012) Vernon W. Dolinsky et al.   JOURNAL OF PHYSIOLOGY-LONDON

Endothelial Dysfunction, Arterial Stiffness, and Heart Failure

(2012) Catherine N. Marti et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Pharmacokinetics of resveratrol metabolic profile in healthy humans after moderate consumption of red wine and grape extract tablets

(2012) Maria Rotches-Ribalta et al.   PHARMACOLOGICAL RESEARCH

Oxidative stress and heart failure

(2011) Hiroyuki Tsutsui et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Calcium Upregulation by Percutaneous Administration of Gene Therapy in Cardiac Disease (CUPID)

(2011) Mariell Jessup et al.   CIRCULATION

Resveratrol prevents endothelial nitric oxide synthase uncoupling and attenuates development of hypertension in spontaneously hypertensive rats

(2011) Siddhartha R. Bhatt et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Resveratrol prevents the wasting disorders of mechanical unloading by acting as a physical exercise mimetic in the rat

(2011) Iman Momken et al.   FASEB JOURNAL

Administration of resveratrol: What formulation solutions to bioavailability limitations?

(2011) A. Amri et al.   JOURNAL OF CONTROLLED RELEASE

Metabolites and tissue distribution of resveratrol in the pig

(2011) María Azorín-Ortuño et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Enhancing the bioavailability of resveratrol by combining it with piperine

(2011) Jeremy J. Johnson et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Modified resveratrol Longevinex improves endothelial function in adults with metabolic syndrome receiving standard treatment

(2011) Keisuke Fujitaka et al.   NUTRITION RESEARCH

Resveratrol Improves Survival, Hemodynamics and Energetics in a Rat Model of Hypertension Leading to Heart Failure

(2011) Stéphanie Rimbaud et al.   PLoS One

Induction of Manganese Superoxide Dismutase by Nuclear Translocation and Activation of SIRT1 Promotes Cell Survival in Chronic Heart Failure

(2010) Masaya Tanno et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Resveratrol Arrests and Regresses the Development of Pressure Overload- but Not Volume Overload-Induced Cardiac Hypertrophy in Rats

(2010) Peter Wojciechowski et al.   JOURNAL OF NUTRITION

Resveratrol and Resveratrol Analogues—Structure—Activity Relationship

(2010) Thomas Szekeres et al.   PHARMACEUTICAL RESEARCH

Resveratrol Prevents the Development of Pathological Cardiac Hypertrophy and Contractile Dysfunction in the SHR Without Lowering Blood Pressure

(2009) S. J. Thandapilly et al.   AMERICAN JOURNAL OF HYPERTENSION

2009 Focused Update Incorporated Into the ACC/AHA 2005 Guidelines for the Diagnosis and Management of Heart Failure in Adults

(2009) et al.   CIRCULATION

Resveratrol prevents doxorubicin cardiotoxicity through mitochondrial stabilization and the Sirt1 pathway

(2009) Elizabeth D. Brookins Danz et al.   FREE RADICAL BIOLOGY AND MEDICINE

Efficacy and Safety of Exercise Training in Patients With Chronic Heart Failure

(2009) Christopher M. O’Connor et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Pharmacokinetics ofTrans-resveratrol Following Repeated Administration in Healthy Elderly and Young Subjects

(2009) Teresa Nunes et al.   JOURNAL OF CLINICAL PHARMACOLOGY

SIRT1, a Longevity Gene, Downregulates Angiotensin II Type 1 Receptor Expression in Vascular Smooth Muscle Cells

(2008) Ryohei Miyazaki et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Resveratrol Attenuates Ventricular Arrhythmias and Improves the Long-Term Survival in Rats with Myocardial Infarction

(2008) You-Ren Chen et al.   CARDIOVASCULAR DRUGS AND THERAPY

Strategic targets to induce neovascularization by resveratrol in hypercholesterolemic rat myocardium: Role of caveolin-1, endothelial nitric oxide synthase, hemeoxygenase-1, and vascular endothelial growth factor

(2008) Suresh Varma Penumathsa et al.   FREE RADICAL BIOLOGY AND MEDICINE

Resveratrol Inhibits Cardiac Hypertrophy via AMP-activated Protein Kinase and Akt

(2008) Anita Y. M. Chan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Resveratrol reduces infarct size and improves ventricular function after myocardial ischemia in rats

(2008) Jeng-Feng Lin et al.   LIFE SCIENCES

Quantification of free and protein-boundtrans-resveratrol metabolites and identification oftrans-resveratrol-C/O-conjugated diglucuronides – Two novel resveratrol metabolites in human plasma

(2008) Alexander Burkon et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Effects of dietary polyphenols on gene expression in human vascular endothelial cells

(2008) Sonja K. Nicholson et al.   PROCEEDINGS OF THE NUTRITION SOCIETY