Mass spectrometry of extracellular vesicles

Biogenesis, Secretion, and Intercellular Interactions of Exosomes and Other Extracellular Vesicles

(2014) Marina Colombo et al.   Annual Review of Cell and Developmental Biology

Microvesicles and exosomes for intracardiac communication

(2014) Joost P.G. Sluijter et al.   CARDIOVASCULAR RESEARCH

Double-stranded DNA in exosomes: a novel biomarker in cancer detection

(2014) Basant Kumar Thakur et al.   CELL RESEARCH

Biogenesis and secretion of exosomes

(2014) Joanna Kowal et al.   CURRENT OPINION IN CELL BIOLOGY

Shotgun proteomics: Identification of unique protein profiles of apoptotic bodies from biliary epithelial cells

(2014) Ana Lleo et al.   HEPATOLOGY

Extracellular vesicles: New players in cardiovascular diseases

(2014) Abderahim Gaceb et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Quantitative Proteomics of Extracellular Vesicles Released from Human Monocyte-Derived Macrophages upon β-Glucan Stimulation

(2014) Wojciech Cypryk et al.   JOURNAL OF PROTEOME RESEARCH

Quantitative proteomic analysis of hepatocyte-secreted extracellular vesicles reveals candidate markers for liver toxicity

(2014) Eva Rodríguez-Suárez et al.   Journal of Proteomics

Proteomic analysis of cerebrospinal fluid extracellular vesicles: A comprehensive dataset

(2014) Davide Chiasserini et al.   Journal of Proteomics

Characterization of secreted vesicles from vascular smooth muscle cells

(2014) Laura Comelli et al.   Molecular BioSystems

Label-free detection and molecular profiling of exosomes with a nano-plasmonic sensor

(2014) Hyungsoon Im et al.   NATURE BIOTECHNOLOGY

Quantitative shotgun proteomics: considerations for a high-quality workflow in immunology

(2014) Felix Meissner et al.   NATURE IMMUNOLOGY

Emerging role of extracellular vesicles in inflammatory diseases

(2014) Edit I. Buzas et al.   Nature Reviews Rheumatology

Proteomic Analysis of C2C12 Myoblast and Myotube Exosome-Like Vesicles: A New Paradigm for Myoblast-Myotube Cross Talk?

(2014) Alexis Forterre et al.   PLoS One

Urinary extracellular microvesicles: Isolation methods and prospects for urinary proteome

(2014) Danqi Wang et al.   PROTEOMICS

Effects of tumor-expressed coagulation factors on cancer progression and venous thrombosis: is there a key factor?

(2014) Betül Ünlü et al.   THROMBOSIS RESEARCH

Extracellular vesicles: emerging targets for cancer therapy

(2014) Pieter Vader et al.   TRENDS IN MOLECULAR MEDICINE

Exosomes: an overview of biogenesis, composition and role in ovarian cancer

(2014) Allison Beach et al.   Journal of Ovarian Research

Post-Translational Modifications of Exosomal Proteins

(2014) Olga Moreno-Gonzalo et al.   Frontiers in Immunology

Molecular lipidomics of exosomes released by PC-3 prostate cancer cells

(2013) Alicia Llorente et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Current methods for the isolation of extracellular vesicles

(2013) Fatemeh Momen-Heravi et al.   BIOLOGICAL CHEMISTRY

Microglia convert aggregated amyloid-β into neurotoxic forms through the shedding of microvesicles

(2013) P Joshi et al.   CELL DEATH AND DIFFERENTIATION

Retinal pigment epithelium (RPE) exosomes contain signaling phosphoproteins affected by oxidative stress

(2013) Lucia Biasutto et al.   EXPERIMENTAL CELL RESEARCH

LRRK2 secretion in exosomes is regulated by 14-3-3

(2013) K. B. Fraser et al.   HUMAN MOLECULAR GENETICS

The Intracellular Interactome of Tetraspanin-enriched Microdomains Reveals Their Function as Sorting Machineries toward Exosomes

(2013) Daniel Perez-Hernandez et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Extracellular vesicles: Exosomes, microvesicles, and friends

(2013) Graça Raposo et al.   JOURNAL OF CELL BIOLOGY

Biogenesis of extracellular vesicles (EV): exosomes, microvesicles, retrovirus-like vesicles, and apoptotic bodies

(2013) Johnny C. Akers et al.   JOURNAL OF NEURO-ONCOLOGY

Bovine milk proteome: Quantitative changes in normal milk exosomes, milk fat globule membranes and whey proteomes resulting from Staphylococcus aureus mastitis

(2013) Timothy A. Reinhardt et al.   Journal of Proteomics

Diabetic nephropathy induces changes in the proteome of human urinary exosomes as revealed by label-free comparative analysis

(2013) Irene Zubiri et al.   Journal of Proteomics

Activin A Suppresses Osteoblast Mineralization Capacity by Altering Extracellular Matrix (ECM) Composition and Impairing Matrix Vesicle (MV) Production

(2013) Rodrigo D. A. M. Alves et al.   MOLECULAR & CELLULAR PROTEOMICS

Urinary exosomes and diabetic nephropathy: a proteomic approach

(2013) F. Raimondo et al.   Molecular BioSystems

Extracellular vesicles: biology and emerging therapeutic opportunities

(2013) Samir EL Andaloussi et al.   NATURE REVIEWS DRUG DISCOVERY

Surface Glycosylation Profiles of Urine Extracellular Vesicles

(2013) Jared Q. Gerlach et al.   PLoS One

Sialoglycoproteins and N-Glycans from Secreted Exosomes of Ovarian Carcinoma Cells

(2013) Cristina Escrevente et al.   PLoS One

Modulation of B-cell exosome proteins by gamma herpesvirus infection

(2013) D. G. Meckes et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Comparative proteomics evaluation of plasma exosome isolation techniques and assessment of the stability of exosomes in normal human blood plasma

(2013) Hina Kalra et al.   PROTEOMICS

Distinct lipid compositions of two types of human prostasomes

(2013) Jos F. Brouwers et al.   PROTEOMICS

Proteomics, transcriptomics and lipidomics of exosomes and ectosomes

(2013) Dong-Sic Choi et al.   PROTEOMICS

Quantitative proteomics of fractionated membrane and lumen exosome proteins from isogenic metastatic and nonmetastatic bladder cancer cells reveal differential expression of EMT factors

(2013) Dennis Kjølhede Jeppesen et al.   PROTEOMICS

Urinary Exosomes as a Source of Kidney Dysfunction Biomarker in Renal Transplantation

(2013) S. Alvarez et al.   TRANSPLANTATION PROCEEDINGS

Proteomic analysis of microvesicles in human saliva by gel electrophoresis with liquid chromatography-mass spectrometry

(2012) Hua Xiao et al.   ANALYTICA CHIMICA ACTA

Antibacterial effect of microvesicles released from human neutrophilic granulocytes

(2012) C. I. Timar et al.   BLOOD

Exosomes: vesicular carriers for intercellular communication in neurodegenerative disorders

(2012) Anja Schneider et al.   CELL AND TISSUE RESEARCH

A hyphenated microLC-Q-TOF-MS platform for exosomal lipidomics investigations: Application to RCC urinary exosomes

(2012) Piero Del Boccio et al.   ELECTROPHORESIS

Microvesicle and tunneling nanotube mediated intercellular transfer of g-protein coupled receptors in cell cultures

(2012) M. Guescini et al.   EXPERIMENTAL CELL RESEARCH

Tumor-derived microvesicles: shedding light on novel microenvironment modulators and prospective cancer biomarkers

(2012) C. D'Souza-Schorey et al.   GENES & DEVELOPMENT

Exosomes and microvesicles: extracellular vesicles for genetic information transfer and gene therapy

(2012) Y. Lee et al.   HUMAN MOLECULAR GENETICS

Membrane Vesicle Release in Bacteria, Eukaryotes, and Archaea: a Conserved yet Underappreciated Aspect of Microbial Life

(2012) Brooke L. Deatherage et al.   INFECTION AND IMMUNITY

Comparative and Targeted Proteomic Analyses of Urinary Microparticles from Bladder Cancer and Hernia Patients

(2012) Chien-Lun Chen et al.   JOURNAL OF PROTEOME RESEARCH

Proteomic Analysis of Trypanosoma cruzi Secretome: Characterization of Two Populations of Extracellular Vesicles and Soluble Proteins

(2012) Ethel Bayer-Santos et al.   JOURNAL OF PROTEOME RESEARCH

Comparative analysis of platelet-derived microparticles reveals differences in their amount and proteome depending on the platelet stimulus

(2012) Ela Shai et al.   Journal of Proteomics

A multiplex quantitative proteomics strategy for protein biomarker studies in urinary exosomes

(2012) Delfin A.A. Raj et al.   KIDNEY INTERNATIONAL

Comparison of protein, microRNA, and mRNA yields using different methods of urinary exosome isolation for the discovery of kidney disease biomarkers

(2012) M. Lucrecia Alvarez et al.   KIDNEY INTERNATIONAL

Comparison of ultracentrifugation, density gradient separation, and immunoaffinity capture methods for isolating human colon cancer cell line LIM1863-derived exosomes

(2012) Bow J. Tauro et al.   METHODS

Characterization of Membrane-shed Microvesicles from Cytokine-stimulated β-Cells Using Proteomics Strategies

(2012) Giuseppe Palmisano et al.   MOLECULAR & CELLULAR PROTEOMICS

Active Wnt proteins are secreted on exosomes

(2012) Julia Christina Gross et al.   NATURE CELL BIOLOGY

Exosomes and the kidney: Blaming the messenger

(2012) Doreen YP Fang et al.   NEPHROLOGY

Small RNA deep sequencing reveals a distinct miRNA signature released in exosomes from prion-infected neuronal cells

(2012) Shayne A. Bellingham et al.   NUCLEIC ACIDS RESEARCH

Deep sequencing of RNA from immune cell-derived vesicles uncovers the selective incorporation of small non-coding RNA biotypes with potential regulatory functions

(2012) Esther N. M. Nolte-’t Hoen et al.   NUCLEIC ACIDS RESEARCH

Exosomal Lipids Impact Notch Signaling and Induce Death of Human Pancreatic Tumoral SOJ-6 Cells

(2012) Sadia Beloribi et al.   PLoS One

Quantitative proteomic analysis of exosomes from HIV-1-infected lymphocytic cells

(2012) Ming Li et al.   PROTEOMICS

Urinary exosomes: A reservoir for biomarker discovery and potential mediators of intrarenal signalling

(2012) James W. Dear et al.   PROTEOMICS

Metabolomics: the final frontier?

(2012) Timothy D Veenstra   Genome Medicine

Vesiclepedia: A Compendium for Extracellular Vesicles with Continuous Community Annotation

(2012) Hina Kalra et al.   PLOS BIOLOGY

Microglial microvesicle secretion and intercellular signaling

(2012) Elena Turola   Frontiers in Physiology

Quantitative, High-Resolution Proteomics for Data-Driven Systems Biology

(2011) Jürgen Cox et al.   Annual Review of Biochemistry

Mechanism of transfer of functional microRNAs between mouse dendritic cells via exosomes

(2011) A. Montecalvo et al.   BLOOD

Membrane vesicles, current state-of-the-art: emerging role of extracellular vesicles

(2011) Bence György et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Amphiregulin Exosomes Increase Cancer Cell Invasion

(2011) James N. Higginbotham et al.   CURRENT BIOLOGY

Exosomes: Small vesicles participating in intercellular communication

(2011) Anna-Kristin Ludwig et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Proteolipidic Composition of Exosomes Changes during Reticulocyte Maturation

(2011) Kévin Carayon et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Liquid Chromatography-Mass Spectrometry-based Quantitative Proteomics

(2011) Fang Xie et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Differential Glycomics of Epithelial Membrane Glycoproteins from Urinary Exovesicles Reveals Shifts toward Complex-Type N-Glycosylation in Classical Galactosemia

(2011) Simon Staubach et al.   JOURNAL OF PROTEOME RESEARCH

Identification of a Conserved Glycan Signature for Microvesicles

(2011) Bianca S. Batista et al.   JOURNAL OF PROTEOME RESEARCH

Proteomic characterization of thymocyte-derived microvesicles and apoptotic bodies in BALB/c mice

(2011) Lilla Turiák et al.   Journal of Proteomics

Characterization of soluble and exosomal forms of the EGFR released from pancreatic cancer cells

(2011) Kamila A. Adamczyk et al.   LIFE SCIENCES

Urinary exosomes and proteomics

(2011) Pyong-Gon Moon et al.   MASS SPECTROMETRY REVIEWS

Expression of PTRF in PC-3 Cells Modulates Cholesterol Dynamics and the Actin Cytoskeleton Impacting Secretion Pathways

(2011) Kerry L. Inder et al.   MOLECULAR & CELLULAR PROTEOMICS

Cancer cell-derived microvesicles induce transformation by transferring tissue transglutaminase and fibronectin to recipient cells

(2011) M. A. Antonyak et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Less label, more free: Approaches in label-free quantitative mass spectrometry

(2011) Karlie A. Neilson et al.   PROTEOMICS

Proteomic analysis of urine exosomes by multidimensional protein identification technology (MudPIT)

(2011) Zhen Wang et al.   PROTEOMICS

Proteomic analysis of urinary exosomes from patients of early IgA nephropathy and thin basement membrane nephropathy

(2011) Pyong-Gon Moon et al.   PROTEOMICS

Urinary Exosomes

(2011) Irena Dimov et al.   TheScientificWorldJOURNAL

Exosome Secretion: Molecular Mechanisms and Roles in Immune Responses

(2011) Angélique Bobrie et al.   TRAFFIC

Unidirectional transfer of microRNA-loaded exosomes from T cells to antigen-presenting cells

(2011) María Mittelbrunn et al.   Nature Communications

Secretion of extracellular hsp90α via exosomes increases cancer cell motility: a role for plasminogen activation

(2010) Jessica McCready et al.   BMC CANCER

Microvesicles: mediators of extracellular communication during cancer progression

(2010) V. Muralidharan-Chari et al.   JOURNAL OF CELL SCIENCE

Proteomics Analysis of Bladder Cancer Exosomes

(2010) Joanne L. Welton et al.   MOLECULAR & CELLULAR PROTEOMICS

Human tumor virus utilizes exosomes for intercellular communication

(2010) D. G. Meckes et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Advances in membranous vesicle and exosome proteomics improving biological understanding and biomarker discovery

(2010) Francesca Raimondo et al.   PROTEOMICS

Candidate biomarkers in exosome-like vesicles purified from rat and mouse urine samples

(2010) Javier Conde-Vancells et al.   Proteomics Clinical Applications

Galectin-5 is bound onto the surface of rat reticulocyte exosomes and modulates vesicle uptake by macrophages

(2009) C. Barres et al.   BLOOD

Prostate cancer-derived urine exosomes: a novel approach to biomarkers for prostate cancer

(2009) J Nilsson et al.   BRITISH JOURNAL OF CANCER

Systemic presence and tumor-growth promoting effect of ovarian carcinoma released exosomes

(2009) Sascha Keller et al.   CANCER LETTERS

Proteomics, Metabolomics, and Immunomics on Microparticles Derived From Human Atherosclerotic Plaques

(2009) Manuel Mayr et al.   Circulation-Cardiovascular Genetics

Exosomes – vesicular carriers for intercellular communication

(2009) Mikael Simons et al.   CURRENT OPINION IN CELL BIOLOGY

Gastric cancer exosomes promote tumour cell proliferation through PI3K/Akt and MAPK/ERK activation

(2009) J.-L. Qu et al.   DIGESTIVE AND LIVER DISEASE

Microenvironmental pH Is a Key Factor for Exosome Traffic in Tumor Cells

(2009) Isabella Parolini et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mass Spectrometry-Based Label-Free Quantitative Proteomics

(2009) Wenhong Zhu et al.   JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY

Proteomic Analysis of Human Parotid Gland Exosomes by Multidimensional Protein Identification Technology (MudPIT)

(2009) Mireya Gonzalez-Begne et al.   JOURNAL OF PROTEOME RESEARCH

Microfluidic isolation and transcriptome analysis of serum microvesicles

(2009) Chihchen Chen et al.   LAB ON A CHIP

Proteomics Analysis of A33 Immunoaffinity-purified Exosomes Released from the Human Colon Tumor Cell Line LIM1215 Reveals a Tissue-specific Protein Signature

(2009) Suresh Mathivanan et al.   MOLECULAR & CELLULAR PROTEOMICS

Phospholipids: Key Players in Apoptosis and Immune Regulation

(2009) Ricardo Chaurio et al.   MOLECULES

Proteomic profiling of human plasma exosomes identifies PPARγ as an exosome-associated protein

(2008) Christopher Looze et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Exosome-Like Vesicles with Dipeptidyl Peptidase IV in Human Saliva

(2008) Yuko Ogawa et al.   BIOLOGICAL & PHARMACEUTICAL BULLETIN

Proteomic and immunologic analyses of brain tumor exosomes

(2008) Michael W. Graner et al.   FASEB JOURNAL

Large-Scale Proteomics and Phosphoproteomics of Urinary Exosomes

(2008) P. A. Gonzales et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Intercellular transfer of the oncogenic receptor EGFRvIII by microvesicles derived from tumour cells

(2008) Khalid Al-Nedawi et al.   NATURE CELL BIOLOGY

Structural heterogeneity and protein composition of exosome-like vesicles (prostasomes) in human semen

(2008) Anton Poliakov et al.   PROSTATE

Ceramide Triggers Budding of Exosome Vesicles into Multivesicular Endosomes

(2008) K. Trajkovic et al.   SCIENCE