High throughput detection of antibody self-interaction by bio-layer interferometry

Rapid Analysis of Antibody Self-Association in Complex Mixtures Using Immunogold Conjugates

(2013) Shantanu V. Sule et al.   MOLECULAR PHARMACEUTICS

Weak Interactions Govern the Viscosity of Concentrated Antibody Solutions: High-Throughput Analysis Using the Diffusion Interaction Parameter

(2012) Brian D. Connolly et al.   BIOPHYSICAL JOURNAL

Solubility evaluation of murine hybridoma antibodies

(2012) Stacey Spencer et al.   mAbs

General strategy for the generation of human antibody variable domains with increased aggregation resistance

(2012) K. Dudgeon et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mechanisms of self-association of a human monoclonal antibody CNTO607

(2012) Deidra Bethea et al.   PROTEIN ENGINEERING DESIGN & SELECTION

Engineering Aggregation-Resistant Antibodies

(2012) Joseph M. Perchiacca et al.   Annual Review of Chemical and Biomolecular Engineering

High-Throughput Analysis of Concentration-Dependent Antibody Self-Association

(2011) Shantanu V. Sule et al.   BIOPHYSICAL JOURNAL

Fc domain mediated self-association of an IgG1 monoclonal antibody under a low ionic strength condition

(2011) Hirotaka Nishi et al.   JOURNAL OF BIOSCIENCE AND BIOENGINEERING

Behavior of Monoclonal Antibodies: Relation Between the Second Virial Coefficient (B 2) at Low Concentrations and Aggregation Propensity and Viscosity at High Concentrations

(2011) Shuntaro Saito et al.   PHARMACEUTICAL RESEARCH

A critical evaluation of self-interaction chromatography as a predictive tool for the assessment of protein–protein interactions in protein formulation development: A case study of a therapeutic monoclonal antibody

(2010) Virginie Le Brun et al.   EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS

Potential Aggregation-Prone Regions in Complementarity-Determining Regions of Antibodies and Their Contribution Towards Antigen Recognition: A Computational Analysis

(2010) Xiaoling Wang et al.   PHARMACEUTICAL RESEARCH

Structure-based engineering of a monoclonal antibody for improved solubility

(2010) S.-J. Wu et al.   PROTEIN ENGINEERING DESIGN & SELECTION

Label-Free Detection of Biomolecular Interactions Using BioLayer Interferometry for Kinetic Characterization

(2009) Joy Concepcion et al.   COMBINATORIAL CHEMISTRY & HIGH THROUGHPUT SCREENING

Specific interactions in high concentration antibody solutions resulting in high viscosity

(2009) Sandeep Yadav et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

Cross-Interaction Chromatography: A Rapid Method to Identify Highly Soluble Monoclonal Antibody Candidates

(2009) Steven A. Jacobs et al.   PHARMACEUTICAL RESEARCH

Exploring blocking assays using Octet, ProteOn, and Biacore biosensors

(2008) Yasmina N. Abdiche et al.   ANALYTICAL BIOCHEMISTRY

Nature and consequences of protein–protein interactions in high protein concentration solutions

(2008) Atul Saluja et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Reversible Self-Association of a Concentrated Monoclonal Antibody Solution Mediated by Fab–Fab Interaction That Impacts Solution Viscosity

(2008) Sonoko Kanai et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

High-Throughput Self-Interaction Chromatography: Applications in Protein Formulation Prediction

(2008) David H. Johnson et al.   PHARMACEUTICAL RESEARCH