The commonPNPLA3variant p.I148M is associated with liver fat contents as quantified by controlled attenuation parameter (CAP)

Transmembrane 6 superfamily member 2 gene variant disentangles nonalcoholic steatohepatitis from cardiovascular disease

(2015) Paola Dongiovanni et al.   HEPATOLOGY

Genetic variation in transmembrane 6 superfamily member 2 and the risk of nonalcoholic fatty liver disease and histological disease severity

(2015) Silvia Sookoian et al.   HEPATOLOGY

PNPLA3gene polymorphism accounts for fatty liver in community subjects without metabolic syndrome

(2014) J. Shen et al.   ALIMENTARY PHARMACOLOGY & THERAPEUTICS

Non-invasive score identifies ultrasonography-diagnosed non-alcoholic fatty liver disease and predicts mortality in the USA

(2014) Ching-Lung Cheung et al.   BMC Medicine

Pnpla3I148Mknockin mice accumulate PNPLA3 on lipid droplets and develop hepatic steatosis

(2014) Eriks Smagris et al.   HEPATOLOGY

PNPLA3 has retinyl-palmitate lipase activity in human hepatic stellate cells

(2014) Carlo Pirazzi et al.   HUMAN MOLECULAR GENETICS

Controlled attenuation parameter for the detection of steatosis severity in chronic liver disease: A meta-analysis of diagnostic accuracy

(2014) Ke-Qing Shi et al.   JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY

The rs738409 (I148M) variant of thePNPLA3gene and cirrhosis: a meta-analysis

(2014) Jian-Hua Shen et al.   JOURNAL OF LIPID RESEARCH

Exome-wide association study identifies a TM6SF2 variant that confers susceptibility to nonalcoholic fatty liver disease

(2014) Julia Kozlitina et al.   NATURE GENETICS

Non-Invasive Assessment of Hepatic Steatosis in Patients with NAFLD Using Controlled Attenuation Parameter and 1H-MR Spectroscopy

(2014) Thomas Karlas et al.   PLoS One

TM6SF2 is a regulator of liver fat metabolism influencing triglyceride secretion and hepatic lipid droplet content

(2014) H. Mahdessian et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Noninvasive characterization of graft steatosis after liver transplantation

(2014) Thomas Karlas et al.   SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY

Controlled attenuation parameter for evaluating liver steatosis in chronic viral hepatitis

(2014) Giovanna Ferraioli   WORLD JOURNAL OF GASTROENTEROLOGY

Recombinant PNPLA3 protein shows triglyceride hydrolase activity and its I148M mutation results in loss of function

(2013) Piero Pingitore et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Utility of controlled attenuation parameter measurement for assessing liver steatosis in Japanese patients with chronic liver diseases

(2013) Keiichi Masaki et al.   HEPATOLOGY RESEARCH

Identification of Combined Genetic Determinants of Liver Stiffness within the SREBP1c-PNPLA3 Pathway

(2013) Marcin Krawczyk et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

The burden of liver disease in Europe: A review of available epidemiological data

(2013) Martin Blachier et al.   JOURNAL OF HEPATOLOGY

How good is controlled attenuation parameter and fatty liver index for assessing liver steatosis in general population: correlation with ultrasound

(2013) Sofia Carvalhana et al.   LIVER INTERNATIONAL

Necessity for timely noninvasive diagnosis of nonalcoholic fatty liver disease

(2013) Stergios A. Polyzos et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

Noninvasive evaluation of NAFLD

(2013) Laurent Castera et al.   Nature Reviews Gastroenterology & Hepatology

The genetics of NAFLD

(2013) Quentin M. Anstee et al.   Nature Reviews Gastroenterology & Hepatology

NAFLD, NASH and liver cancer

(2013) Gregory A. Michelotti et al.   Nature Reviews Gastroenterology & Hepatology

PNPLA3-Associated Steatohepatitis: Toward a Gene-Based Classification of Fatty Liver Disease

(2013) Marcin Krawczyk et al.   SEMINARS IN LIVER DISEASE

PNPLA3 I148M polymorphism and progressive liver disease

(2013) Paola Dongiovanni   WORLD JOURNAL OF GASTROENTEROLOGY

Adiponutrin Functions as a Nutritionally Regulated Lysophosphatidic Acid Acyltransferase

(2012) Manju Kumari et al.   Cell Metabolism

Common genetic variation in vitamin D metabolism is associated with liver stiffness

(2012) Frank Grünhage et al.   HEPATOLOGY

Determination of reliability criteria for liver stiffness evaluation by transient elastography

(2012) Jérôme Boursier et al.   HEPATOLOGY

Non-invasive diagnosis of liver steatosis using controlled attenuation parameter (CAP) and transient elastography

(2012) Victor Lédinghen et al.   LIVER INTERNATIONAL

Nonalcoholic fatty liver disease

(2011) Marcin Krawczyk et al.   BEST PRACTICE & RESEARCH IN CLINICAL GASTROENTEROLOGY

Novel controlled attenuation parameter for noninvasive assessment of steatosis using Fibroscan®: validation in chronic hepatitis C

(2011) M. Sasso et al.   JOURNAL OF VIRAL HEPATITIS

Homozygosity for the patatin-like phospholipase-3/adiponutrin I148M polymorphism influences liver fibrosis in patients with nonalcoholic fatty liver disease

(2010) Luca Valenti et al.   HEPATOLOGY

Variant adiponutrin (PNPLA3) represents a common fibrosis risk gene: Non-invasive elastography-based study in chronic liver disease

(2010) Marcin Krawczyk et al.   JOURNAL OF HEPATOLOGY

Bioelectrical Impedance Analysis for Evaluation of Donor Hepatic Steatosis in Living-Donor Liver Transplantation

(2010) S. Hwang et al.   TRANSPLANTATION PROCEEDINGS

Controlled Attenuation Parameter (CAP): A Novel VCTE™ Guided Ultrasonic Attenuation Measurement for the Evaluation of Hepatic Steatosis: Preliminary Study and Validation in a Cohort of Patients with Chronic Liver Disease from Various Causes

(2010) Magali Sasso et al.   ULTRASOUND IN MEDICINE AND BIOLOGY

Non-invasive evaluation of liver fibrosis using transient elastography

(2008) Laurent Castera et al.   JOURNAL OF HEPATOLOGY

Genetic variation in PNPLA3 confers susceptibility to nonalcoholic fatty liver disease

(2008) Stefano Romeo et al.   NATURE GENETICS