Prioritization of Genetic Variants in the microRNA Regulome as Functional Candidates in Genome-Wide Association Studies

Genetic Architecture of MicroRNA Expression: Implications for the Transcriptome and Complex Traits

(2012) Eric R. Gamazon et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Gain-of-Function Lipoprotein Lipase Variant rs13702 Modulates Lipid Traits through Disruption of a MicroRNA-410 Seed Site

(2012) Kris Richardson et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Evaluating our ability to predict the structural disruption of RNA by SNPs

(2012) Justin Ritz et al.   BMC GENOMICS

miRdSNP: a database of disease-associated SNPs and microRNA target sites on 3'UTRs of human genes

(2012) Andrew E Bruno et al.   BMC GENOMICS

Genetic polymorphism at miR-181a binding site contributes to gastric cancer susceptibility

(2012) Yong Lin et al.   CARCINOGENESIS

miR-192, miR-194, miR-215, miR-200c and miR-141 are downregulated and their common target ACVR2B is strongly expressed in renal childhood neoplasms

(2012) U. Senanayake et al.   CARCINOGENESIS

Roles for MicroRNAs in Conferring Robustness to Biological Processes

(2012) Margaret S. Ebert et al.   CELL

Developing MicroRNA Therapeutics

(2012) Eva van Rooij et al.   CIRCULATION RESEARCH

Impact of microRNA regulation on variation in human gene expression

(2012) J. Lu et al.   GENOME RESEARCH

Identification of microRNA-regulated gene networks by expression analysis of target genes

(2012) Vincenzo Alessandro Gennarino et al.   GENOME RESEARCH

Linking disease associations with regulatory information in the human genome

(2012) M. A. Schaub et al.   GENOME RESEARCH

Annotation of functional variation in personal genomes using RegulomeDB

(2012) A. P. Boyle et al.   GENOME RESEARCH

DNase I sensitivity QTLs are a major determinant of human expression variation

(2012) Jacob F. Degner et al.   NATURE

An integrated encyclopedia of DNA elements in the human genome

(2012)   NATURE

An integrated map of genetic variation from 1,092 human genomes

(2012)   NATURE

Puzzling over schizophrenia: Schizophrenia as a pathway disease

(2012) Patrick F Sullivan   NATURE MEDICINE

An alternative mode of microRNA target recognition

(2012) Sung Wook Chi et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Catalog of MicroRNA Seed Polymorphisms in Vertebrates

(2012) Minja Zorc et al.   PLoS One

Cis-Acting Polymorphisms Affect Complex Traits through Modifications of MicroRNA Regulation Pathways

(2012) Matthias Arnold et al.   PLoS One

Systematic Analysis of microRNA Targeting Impacted by Small Insertions and Deletions in Human Genome

(2012) Anindya Bhattacharya et al.   PLoS One

Common Genetic Variants in miR-1206 (8q24.2) and miR-612 (11q13.3) Affect Biogenesis of Mature miRNA Forms

(2012) Hye Kyung Kim et al.   PLoS One

MicroRNA-mediated regulation of gene expression is affected by disease-associated SNPs within the 3′-UTR via altered RNA structure

(2012) Ulrike Haas et al.   RNA Biology

Systematic Localization of Common Disease-Associated Variation in Regulatory DNA

(2012) M. T. Maurano et al.   SCIENCE

Evidence for Positive Selection on a Number of MicroRNA Regulatory Interactions during Recent Human Evolution

(2012) Jingjing Li et al.   PLoS Genetics

Dissecting the regulatory architecture of gene expression QTLs

(2012) Daniel J Gaffney et al.   GENOME BIOLOGY

A genome-wide survey for SNPs altering microRNA seed sites identifies functional candidates in GWAS

(2011) Kris Richardson et al.   BMC GENOMICS

The code within the code: microRNAs target coding regions

(2011) Joshua J. Forman et al.   CELL CYCLE

The Influence of 3′UTRs on MicroRNA Function Inferred from Human SNP Data

(2011) Zihua Hu et al.   COMPARATIVE AND FUNCTIONAL GENOMICS

Unusually effective microRNA targeting within repeat-rich coding regions of mammalian mRNAs

(2011) M. Schnall-Levin et al.   GENOME RESEARCH

Genome-wide identification of SNPs in microRNA genes and the SNP effects on microRNA target binding and biogenesis

(2011) Jing Gong et al.   HUMAN MUTATION

Mapping and analysis of chromatin state dynamics in nine human cell types

(2011) Jason Ernst et al.   NATURE

9p21 DNA variants associated with coronary artery disease impair interferon-γ signalling response

(2011) Olivier Harismendy et al.   NATURE

The long and winding road from correlation to causation

(2011) Michel Georges   NATURE GENETICS

A synonymous variant in IRGM alters a binding site for miR-196 and causes deregulation of IRGM-dependent xenophagy in Crohn's disease

(2011) Patrick Brest et al.   NATURE GENETICS

Genome-wide association study identifies five new schizophrenia loci

(2011)   NATURE GENETICS

Identification and Characterization of Sall1-Expressing Cells Present in the Adult Mouse Kidney

(2011) M. Joynal Abedin et al.   NEPHRON EXPERIMENTAL NEPHROLOGY

Inferring causative variants in microRNA target sites

(2011) Laurent F. Thomas et al.   NUCLEIC ACIDS RESEARCH

PolymiRTS Database 2.0: linking polymorphisms in microRNA target sites with human diseases and complex traits

(2011) J. D. Ziebarth et al.   NUCLEIC ACIDS RESEARCH

GWASdb: a database for human genetic variants identified by genome-wide association studies

(2011) Mulin Jun Li et al.   NUCLEIC ACIDS RESEARCH

Wide-ranging functions of E2F4 in transcriptional activation and repression revealed by genome-wide analysis

(2011) Bum-Kyu Lee et al.   NUCLEIC ACIDS RESEARCH

dPORE-miRNA: Polymorphic Regulation of MicroRNA Genes

(2011) Sebastian Schmeier et al.   PLoS One

The Impact of miRNA Target Sites in Coding Sequences and in 3′UTRs

(2011) Zhuo Fang et al.   PLoS One

Multiplexed RNA structure characterization with selective 2'-hydroxyl acylation analyzed by primer extension sequencing (SHAPE-Seq)

(2011) J. B. Lucks et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A Functional Variant in MicroRNA-146a Promoter Modulates Its Expression and Confers Disease Risk for Systemic Lupus Erythematosus

(2011) Xiaobing Luo et al.   PLoS Genetics

MiRSNPs or MiR-polymorphisms, new players in microRNA mediated regulation of the cell: Introducing microRNA pharmacogenomics

(2010) Prasun J. Mishra et al.   CELL CYCLE

Global Epigenomic Analysis of Primary Human Pancreatic Islets Provides Insights into Type 2 Diabetes Susceptibility Loci

(2010) Michael L. Stitzel et al.   Cell Metabolism

Reprogramming of miRNA networks in cancer and leukemia

(2010) S. Volinia et al.   GENOME RESEARCH

MicroSNiPer: a web tool for prediction of SNP effects on putative microRNA targets

(2010) Maxim Barenboim et al.   HUMAN MUTATION

Expanding the MicroRNA Targeting Code: Functional Sites with Centered Pairing

(2010) Chanseok Shin et al.   MOLECULAR CELL

From noncoding variant to phenotype via SORT1 at the 1p13 cholesterol locus

(2010) Kiran Musunuru et al.   NATURE

Integrating common and rare genetic variation in diverse human populations

(2010)   NATURE

A map of open chromatin in human pancreatic islets

(2010) Kyle J Gaulton et al.   NATURE GENETICS

Identifying gene regulatory networks in schizophrenia

(2010) Steven G. Potkin et al.   NEUROIMAGE

miRBase: integrating microRNA annotation and deep-sequencing data

(2010) A. Kozomara et al.   NUCLEIC ACIDS RESEARCH

MicroRNA-181a modulates gene expression of zinc finger family members by directly targeting their coding regions

(2010) Shenglin Huang et al.   NUCLEIC ACIDS RESEARCH

Candidate Causal Regulatory Effects by Integration of Expression QTLs with Complex Trait Genetic Associations

(2010) Alexandra C. Nica et al.   PLoS Genetics

Trait-Associated SNPs Are More Likely to Be eQTLs: Annotation to Enhance Discovery from GWAS

(2010) Dan L. Nicolae et al.   PLoS Genetics

Disease-Associated Mutations That Alter the RNA Structural Ensemble

(2010) Matthew Halvorsen et al.   PLoS Genetics

Signatures of Purifying and Local Positive Selection in Human miRNAs

(2009) Hélène Quach et al.   AMERICAN JOURNAL OF HUMAN GENETICS

dbSMR: a novel resource of genome-wide SNPs affecting microRNA mediated regulation

(2009) Manoj Hariharan et al.   BMC BIOINFORMATICS

Annotation of mammalian primary microRNAs

(2009) Harpreet K Saini et al.   BMC GENOMICS

MicroRNAs: Target Recognition and Regulatory Functions

(2009) David P. Bartel   CELL

Chromatin poises miRNA- and protein-coding genes for expression

(2009) A. Barski et al.   GENOME RESEARCH

Lowly Expressed Human MicroRNA Genes Evolve Rapidly

(2009) Han Liang et al.   MOLECULAR BIOLOGY AND EVOLUTION

Allelic imbalance sequencing reveals that single-nucleotide polymorphisms frequently alter microRNA-directed repression

(2009) Jinkuk Kim et al.   NATURE BIOTECHNOLOGY

The 8q24 cancer risk variant rs6983267 shows long-range interaction with MYC in colorectal cancer

(2009) Mark M Pomerantz et al.   NATURE GENETICS

Biogenesis of small RNAs in animals

(2009) V. Narry Kim et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Patrocles: a database of polymorphic miRNA-mediated gene regulation in vertebrates

(2009) Samuel Hiard et al.   NUCLEIC ACIDS RESEARCH

Features of Mammalian microRNA Promoters Emerge from Polymerase II Chromatin Immunoprecipitation Data

(2009) David L. Corcoran et al.   PLoS One

Potential etiologic and functional implications of genome-wide association loci for human diseases and traits

(2009) L. A. Hindorff et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Polymorphisms in microRNA targets: a gold mine for molecular epidemiology

(2008) K. Chen et al.   CARCINOGENESIS

Connecting microRNA Genes to the Core Transcriptional Regulatory Circuitry of Embryonic Stem Cells

(2008) Alexander Marson et al.   CELL

Chromatin structure analyses identify miRNA promoters

(2008) F. Ozsolak et al.   GENES & DEVELOPMENT

Most mammalian mRNAs are conserved targets of microRNAs

(2008) R. C. Friedman et al.   GENOME RESEARCH

Functional genetic variation of human miRNAs and phenotypic consequences

(2008) Christelle Borel et al.   MAMMALIAN GENOME

Serum C-reactive protein is an independent risk factor predicting cardiometabolic risk

(2008) Altan Onat et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

Accurate SHAPE-directed RNA structure determination

(2008) K. E. Deigan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Circulating microRNAs as stable blood-based markers for cancer detection

(2008) P. S. Mitchell et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The let-7 family of microRNAs

(2008) Sarah Roush et al.   TRENDS IN CELL BIOLOGY

MicroRNA target site polymorphisms and human disease

(2008) Praveen Sethupathy et al.   TRENDS IN GENETICS