- Home
- Publications
- Publication Search
- Publication Details
Title
The DcpS inhibitor RG3039 improves motor function in SMA mice
Authors
Keywords
-
Journal
HUMAN MOLECULAR GENETICS
Volume 22, Issue 20, Pages 4074-4083
Publisher
Oxford University Press (OUP)
Online
2013-06-01
DOI
10.1093/hmg/ddt257
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- An SMN-Dependent U12 Splicing Event Essential for Motor Circuit Function
- (2012) Francesco Lotti et al. CELL
- SMN Is Required for Sensory-Motor Circuit Function in Drosophila
- (2012) Wendy L. Imlach et al. CELL
- Motor Neuron Rescue in Spinal Muscular Atrophy Mice Demonstrates That Sensory-Motor Defects Are a Consequence, Not a Cause, of Motor Neuron Dysfunction
- (2012) R. G. Gogliotti et al. JOURNAL OF NEUROSCIENCE
- Survival Motor Neuron Protein in Motor Neurons Determines Synaptic Integrity in Spinal Muscular Atrophy
- (2012) T. L. Martinez et al. JOURNAL OF NEUROSCIENCE
- Synaptic defects in type I spinal muscular atrophy in human development
- (2012) Rebeca Martínez-Hernández et al. JOURNAL OF PATHOLOGY
- Dysfunction of the neuromuscular junction in spinal muscular atrophy types 2 and 3
- (2012) R. I. Wadman et al. NEUROLOGY
- Limited Phenotypic Effects of Selectively Augmenting the SMN Protein in the Neurons of a Mouse Model of Severe Spinal Muscular Atrophy
- (2012) Andrew J-H. Lee et al. PLoS One
- Muscles in a mouse model of spinal muscular atrophy show profound defects in neuromuscular development even in the absence of failure in neuromuscular transmission or loss of motor neurons
- (2011) Young il Lee et al. DEVELOPMENTAL BIOLOGY
- The contribution of mouse models to understanding the pathogenesis of spinal muscular atrophy
- (2011) J. N. Sleigh et al. Disease Models & Mechanisms
- Temporal requirement for high SMN expression in SMA mice
- (2011) T. T. Le et al. HUMAN MOLECULAR GENETICS
- A single administration of morpholino antisense oligomer rescues spinal muscular atrophy in mouse
- (2011) Paul N. Porensky et al. HUMAN MOLECULAR GENETICS
- Severe neuromuscular denervation of clinically relevant muscles in a mouse model of spinal muscular atrophy
- (2011) K. K. Y. Ling et al. HUMAN MOLECULAR GENETICS
- Postsymptomatic restoration of SMN rescues the disease phenotype in a mouse model of severe spinal muscular atrophy
- (2011) Cathleen M. Lutz et al. JOURNAL OF CLINICAL INVESTIGATION
- Defective Neuromuscular Junction Organization and Postnatal Myogenesis in Mice With Severe Spinal Muscular Atrophy
- (2011) Elisabet Dachs et al. JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY
- A Role for SMN Exon 7 Splicing in the Selective Vulnerability of Motor Neurons in Spinal Muscular Atrophy
- (2011) M. Ruggiu et al. MOLECULAR AND CELLULAR BIOLOGY
- Peripheral SMN restoration is essential for long-term rescue of a severe spinal muscular atrophy mouse model
- (2011) Yimin Hua et al. NATURE
- Early Functional Impairment of Sensory-Motor Connectivity in a Mouse Model of Spinal Muscular Atrophy
- (2011) George Z. Mentis et al. NEURON
- Antisense Oligonucleotides Delivered to the Mouse CNS Ameliorate Symptoms of Severe Spinal Muscular Atrophy
- (2011) M. A. Passini et al. Science Translational Medicine
- Spinal Muscular Atrophy: New and Emerging Insights from Model Mice
- (2010) Gyu-Hwan Park et al. Current Neurology and Neuroscience Reports
- Intravenous scAAV9 delivery of a codon-optimized SMN1 sequence rescues SMA mice
- (2010) Elisa Dominguez et al. HUMAN MOLECULAR GENETICS
- A feedback loop regulates splicing of the spinal muscular atrophy-modifying gene, SMN2
- (2010) Francine M. Jodelka et al. HUMAN MOLECULAR GENETICS
- CNS-targeted gene therapy improves survival and motor function in a mouse model of spinal muscular atrophy
- (2010) Marco A. Passini et al. JOURNAL OF CLINICAL INVESTIGATION
- Altered Intracellular Ca2+ Homeostasis in Nerve Terminals of Severe Spinal Muscular Atrophy Mice
- (2010) R. Ruiz et al. JOURNAL OF NEUROSCIENCE
- Rescue of the spinal muscular atrophy phenotype in a mouse model by early postnatal delivery of SMN
- (2010) Kevin D Foust et al. NATURE BIOTECHNOLOGY
- Synaptic Defects in the Spinal and Neuromuscular Circuitry in a Mouse Model of Spinal Muscular Atrophy
- (2010) Karen K. Y. Ling et al. PLoS One
- Effects of 2,4-diaminoquinazoline derivatives on SMN expression and phenotype in a mouse model for spinal muscular atrophy
- (2009) Matthew E.R. Butchbach et al. HUMAN MOLECULAR GENETICS
- Impaired Synaptic Vesicle Release and Immaturity of Neuromuscular Junctions in Spinal Muscular Atrophy Mice
- (2009) L. Kong et al. JOURNAL OF NEUROSCIENCE
- Alternative Splicing Events Are a Late Feature of Pathology in a Mouse Model of Spinal Muscular Atrophy
- (2009) Dirk Bäumer et al. PLoS Genetics
- DcpS as a Therapeutic Target for Spinal Muscular Atrophy
- (2008) Jasbir Singh et al. ACS Chemical Biology
- SMN Deficiency Causes Tissue-Specific Perturbations in the Repertoire of snRNAs and Widespread Defects in Splicing
- (2008) Zhenxi Zhang et al. CELL
- Reduced SMN protein impairs maturation of the neuromuscular junctions in mouse models of spinal muscular atrophy
- (2008) Shingo Kariya et al. HUMAN MOLECULAR GENETICS
- Synthesis and Biological Evaluation of Novel 2,4-Diaminoquinazoline Derivatives asSMN2Promoter Activators for the Potential Treatment of Spinal Muscular Atrophy
- (2008) John Thurmond et al. JOURNAL OF MEDICINAL CHEMISTRY
- DcpS scavenger decapping enzyme can modulate pre-mRNA splicing
- (2008) V. Shen et al. RNA
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreCreate your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create Now