Dopaminergic expression of the Parkinsonian gene LRRK2-G2019S leads to non-autonomous visual neurodegeneration, accelerated by increased neural demands for energy

parkin-induced defects in neurophysiology and locomotion are generated by metabolic dysfunction and not oxidative stress

(2012) A. Vincent et al.   HUMAN MOLECULAR GENETICS

AMP Kinase Activation Mitigates Dopaminergic Dysfunction and Mitochondrial Abnormalities in Drosophila Models of Parkinson's Disease

(2012) C.-H. Ng et al.   JOURNAL OF NEUROSCIENCE

Zinc supplement greatly improves the condition of parkin mutant Drosophila

(2010) Nidhi Saini et al.   BIOLOGICAL CHEMISTRY

Roles of Dopamine in Circadian Rhythmicity and Extreme Light Sensitivity of Circadian Entrainment

(2010) Jay Hirsh et al.   CURRENT BIOLOGY

Parkinson's disease: insights from pathways

(2010) M. R. Cookson et al.   HUMAN MOLECULAR GENETICS

Hyperexcitable Substantia Nigra Dopamine Neurons in PINK1- and HtrA2/Omi-Deficient Mice

(2010) Matthew W. Bishop et al.   JOURNAL OF NEUROPHYSIOLOGY

LRRK2 Kinase Regulates Synaptic Morphology through Distinct Substrates at the Presynaptic and Postsynaptic Compartments of the Drosophila Neuromuscular Junction

(2010) S. Lee et al.   JOURNAL OF NEUROSCIENCE

LRRK2 G2019S Mutation Induces Dendrite Degeneration through Mislocalization and Phosphorylation of Tau by Recruiting Autoactivated GSK3 

(2010) C.-H. Lin et al.   JOURNAL OF NEUROSCIENCE

Enhanced Striatal Dopamine Transmission and Motor Performance with LRRK2 Overexpression in Mice Is Eliminated by Familial Parkinson's Disease Mutation G2019S

(2010) X. Li et al.   JOURNAL OF NEUROSCIENCE

Oxidant stress evoked by pacemaking in dopaminergic neurons is attenuated by DJ-1

(2010) Jaime N. Guzman et al.   NATURE

Extended lifespan of Drosophila parkin mutants through sequestration of redox-active metals and enhancement of anti-oxidative pathways

(2010) Nidhi Saini et al.   NEUROBIOLOGY OF DISEASE

Mitochondrial impairment in patients with Parkinson disease with the G2019S mutation in LRRK2

(2010) H. Mortiboys et al.   NEUROLOGY

Design Principles of Insect and Vertebrate Visual Systems

(2010) Joshua R. Sanes et al.   NEURON

Leucine-Rich Repeat Kinase 2 Mutations and Parkinson's Disease: Three Questions

(2009) Elisa Greggio et al.   ASN Neuro

The retina in Parkinson's disease

(2009) N. K. Archibald et al.   BRAIN

Writing Memories with Light-Addressable Reinforcement Circuitry

(2009) Adam Claridge-Chang et al.   CELL

The cleaved-Caspase-3 antibody is a marker of Caspase-9-like DRONC activity in Drosophila

(2009) Y Fan et al.   CELL DEATH AND DIFFERENTIATION

LRRK2 in Parkinson’s disease: genetic and clinical studies from patients

(2009) Udhaya Kumari et al.   FEBS Journal

Leucine-rich repeat kinase 2 interacts with Parkin, DJ-1 and PINK-1 in a Drosophila melanogaster model of Parkinson's disease

(2009) K. Venderova et al.   HUMAN MOLECULAR GENETICS

Parkin Protects against LRRK2 G2019S Mutant-Induced Dopaminergic Neurodegeneration in Drosophila

(2009) C.-H. Ng et al.   JOURNAL OF NEUROSCIENCE

Normal dendrite growth inDrosophilamotor neurons requires the AP-1 transcription factor

(2008) Cortnie L. Hartwig et al.   Developmental Neurobiology

Phosphorylation of 4E-BP by LRRK2 affects the maintenance of dopaminergic neurons in Drosophila

(2008) Yuzuru Imai et al.   EMBO JOURNAL

An Optimized Method for Histological Detection of Dopaminergic Neurons in Drosophila melanogaster

(2008) Daria Drobysheva et al.   JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY

Dendrite Elongation and Dendritic Branching Are Affected Separately by Different Forms of Intrinsic Motoneuron Excitability

(2008) Carsten Duch et al.   JOURNAL OF NEUROPHYSIOLOGY

Dispensable role of Drosophila ortholog of LRRK2 kinase activity in survival of dopaminergic neurons

(2008) Danling Wang et al.   Molecular Neurodegeneration

The Neural Substrate of Spectral Preference in Drosophila

(2008) Shuying Gao et al.   NEURON

The Circadian Clock in the Retina Controls Rod-Cone Coupling

(2008) Christophe Ribelayga et al.   NEURON

The biology and pathobiology of LRRK2: Implications for Parkinson's disease

(2008) Darren J. Moore   PARKINSONISM & RELATED DISORDERS

A Drosophila model for LRRK2-linked parkinsonism

(2008) Z. Liu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Conservation of sleep: insights from non-mammalian model systems

(2008) John E. Zimmerman et al.   TRENDS IN NEUROSCIENCES