Different mtDNA mutations modify tumor progression in dependence of the degree of respiratory complex I impairment
Published 2013 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Different mtDNA mutations modify tumor progression in dependence of the degree of respiratory complex I impairment
Authors
Keywords
-
Journal
HUMAN MOLECULAR GENETICS
Volume 23, Issue 6, Pages 1453-1466
Publisher
Oxford University Press (OUP)
Online
2013-10-26
DOI
10.1093/hmg/ddt533
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- The Proto-oncometabolite Fumarate Binds Glutathione to Amplify ROS-Dependent Signaling
- (2013) Lucas B. Sullivan et al. MOLECULAR CELL
- Relevance of Mitochondrial Genetics and Metabolism in Cancer Development
- (2013) G. Gasparre et al. Cold Spring Harbor Perspectives in Biology
- Somatic mitochondrial DNA mutations in cancer escape purifying selection and high pathogenicity mutations lead to the oncocytic phenotype: pathogenicity analysis of reported somatic mtDNA mutations in tumors
- (2012) Luísa Pereira et al. BMC CANCER
- AMPK Is a Negative Regulator of the Warburg Effect and Suppresses Tumor Growth In Vivo
- (2012) Brandon Faubert et al. Cell Metabolism
- PI3K/AKT, MAPK and AMPK signalling: protein kinases in glucose homeostasis
- (2012) Simon M. Schultze et al. EXPERT REVIEWS IN MOLECULAR MEDICINE
- Universal heteroplasmy of human mitochondrial DNA
- (2012) B. A. I. Payne et al. HUMAN MOLECULAR GENETICS
- Somatic complex I disruptive mitochondrial DNA mutations are modifiers of tumorigenesis that correlate with low genomic instability in pituitary adenomas
- (2012) I. Kurelac et al. HUMAN MOLECULAR GENETICS
- Complex I impairment in mitochondrial diseases and cancer: Parallel roads leading to different outcomes
- (2012) Luisa Iommarini et al. INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY
- NIH Image to ImageJ: 25 years of image analysis
- (2012) Caroline A Schneider et al. NATURE METHODS
- Human mitochondrial DNA: roles of inherited and somatic mutations
- (2012) Eric A. Schon et al. NATURE REVIEWS GENETICS
- Spectrum of somatic mitochondrial mutations in five cancers
- (2012) T. C. Larman et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The effects of idebenone on mitochondrial bioenergetics
- (2011) Valentina Giorgio et al. BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS
- The Glycolytic Shift in Fumarate-Hydratase-Deficient Kidney Cancer Lowers AMPK Levels, Increases Anabolic Propensities and Lowers Cellular Iron Levels
- (2011) Wing-Hang Tong et al. CANCER CELL
- A Mutation Threshold Distinguishes the Antitumorigenic Effects of the Mitochondrial Gene MTND1, an Oncojanus Function
- (2011) G. Gasparre et al. CANCER RESEARCH
- Mitochondrial respiratory complex I dysfunction promotes tumorigenesis through ROS alteration and AKT activation
- (2011) Lokendra Kumar Sharma et al. HUMAN MOLECULAR GENETICS
- Mitochondrial DNA mutations in respiratory complex-I in never-smoker lung cancer patients contribute to lung cancer progression and associated withEGFRgene mutation
- (2011) Santanu Dasgupta et al. JOURNAL OF CELLULAR PHYSIOLOGY
- Pharmacological targeting of mitochondrial complex I deficiency: The cellular level and beyond
- (2011) Peggy Roestenberg et al. MITOCHONDRION
- Genetic insights into OXPHOS defect and its role in cancer
- (2010) Dhyan Chandra et al. BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS
- The Role of Mitochondria in the Pathogenesis of Type 2 Diabetes
- (2010) Mary-Elizabeth Patti et al. ENDOCRINE REVIEWS
- Hypoxia-Inducible Factors and the Response to Hypoxic Stress
- (2010) Amar J. Majmundar et al. MOLECULAR CELL
- Heteroplasmic mitochondrial DNA mutations in normal and tumour cells
- (2010) Yiping He et al. NATURE
- Mitochondrial complex I deficiency: from organelle dysfunction to clinical disease
- (2009) F. Distelmaier et al. BRAIN
- Implications of mitochondrial DNA mutations and mitochondrial dysfunction in tumorigenesis
- (2009) Jianxin Lu et al. CELL RESEARCH
- Akt-dependent and -independent mechanisms of mTOR regulation in cancer
- (2009) Regan M. Memmott et al. CELLULAR SIGNALLING
- Mitochondrial Mutations Contribute to HIF1 Accumulation via Increased Reactive Oxygen Species and Up-regulated Pyruvate Dehydrogenease Kinase 2 in Head and Neck Squamous Cell Carcinoma
- (2009) W. Sun et al. CLINICAL CANCER RESEARCH
- The genetic and metabolic signature of oncocytic transformation implicates HIF1α destabilization
- (2009) Anna Maria Porcelli et al. HUMAN MOLECULAR GENETICS
- A heteroplasmic, not homoplasmic, mitochondrial DNA mutation promotes tumorigenesis via alteration in reactive oxygen species generation and apoptosis
- (2009) J. S. Park et al. HUMAN MOLECULAR GENETICS
- Reactive Oxygen Species-generating Mitochondrial DNA Mutation Up-regulates Hypoxia-inducible Factor-1α Gene Transcription via Phosphatidylinositol 3-Kinase-Akt/Protein Kinase C/Histone Deacetylase Pathway
- (2009) Nobuko Koshikawa et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- mTOR and HIF-1 -mediated tumor metabolism in an LKB1 mouse model of Peutz-Jeghers syndrome
- (2009) D. B. Shackelford et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The Biology of Cancer: Metabolic Reprogramming Fuels Cell Growth and Proliferation
- (2008) Ralph J. DeBerardinis et al. Cell Metabolism
- The antioxidant function of Bcl-2 preserves cytoskeletal stability of cells with defective respiratory complex I
- (2008) A. M. Porcelli et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- Respiratory Complex I Dysfunction Due to Mitochondrial DNA Mutations Shifts the Voltage Threshold for Opening of the Permeability Transition Pore toward Resting Levels
- (2008) Anna Maria Porcelli et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- ROS-Generating Mitochondrial DNA Mutations Can Regulate Tumor Cell Metastasis
- (2008) K. Ishikawa et al. SCIENCE
Create your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create NowBecome a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get Started