Alleviation of seipinopathy-related ER stress by triglyceride storage

Overexpression of a short human seipin/BSCL2 isoform in mouse adipose tissue results in mild lipodystrophy

(2012) Xin Cui et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Endosomal Actin Remodeling by Coronin-1A Controls Lipoprotein Uptake and Degradation in Macrophages

(2012) Maarit Hölttä-Vuori et al.   CIRCULATION RESEARCH

Absence of adipose triglyceride lipase protects from hepatic endoplasmic reticulum stress in mice

(2012) Claudia D. Fuchs et al.   HEPATOLOGY

Spg20−/− mice reveal multimodal functions for Troyer syndrome protein spartin in lipid droplet maintenance, cytokinesis and BMP signaling

(2012) Benoît Renvoisé et al.   HUMAN MOLECULAR GENETICS

Seipin: from human disease to molecular mechanism

(2012) Bethany R. Cartwright et al.   JOURNAL OF LIPID RESEARCH

Is fat so bad? Modulation of endoplasmic reticulum stress by lipid droplet formation

(2011) Ivan Hapala et al.   BIOLOGY OF THE CELL

Oleate Blocks Palmitate-Induced Abnormal Lipid Distribution, Endoplasmic Reticulum Expansion and Stress, and Insulin Resistance in Skeletal Muscle

(2011) Gong Peng et al.   ENDOCRINOLOGY

Lipin-1γ isoform is a novel lipid droplet-associated protein highly expressed in the brain

(2011) Huajin Wang et al.   FEBS LETTERS

N88S seipin mutant transgenic mice develop features of seipinopathy/BSCL2-related motor neuron disease via endoplasmic reticulum stress

(2011) Takuya Yagi et al.   HUMAN MOLECULAR GENETICS

Characterization of inclusion bodies with cytoprotective properties formed by seipinopathy-linked mutant seipin

(2011) Daisuke Ito et al.   HUMAN MOLECULAR GENETICS

A role for seipin in lipid droplet dynamics and inheritance in yeast

(2011) H. Wolinski et al.   JOURNAL OF CELL SCIENCE

Molecular characterization of seipin and its mutants: implications for seipin in triacylglycerol synthesis

(2011) Weihua Fei et al.   JOURNAL OF LIPID RESEARCH

Transposon-mediated BAC transgenesis in zebrafish

(2011) Maximiliano L Suster et al.   Nature Protocols

Selective activation of the transcription factor ATF6 mediates endoplasmic reticulum proliferation triggered by a membrane protein

(2011) J. Maiuolo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Zebrafish: gaining popularity in lipid research

(2010) Maarit Hölttä-Vuori et al.   BIOCHEMICAL JOURNAL

Seipin Is a Discrete Homooligomer

(2010) Derk Binns et al.   BIOCHEMISTRY

Biochemistry, physiology, and genetics of GPAT, AGPAT, and lipin enzymes in triglyceride synthesis

(2009) Kazuharu Takeuchi et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

The Human Lipodystrophy Gene Product Berardinelli-Seip Congenital Lipodystrophy 2/Seipin Plays a Key Role in Adipocyte Differentiation

(2009) Weiqin Chen et al.   ENDOCRINOLOGY

Complementary developmental expression of the two tyrosine hydroxylase transcripts in zebrafish

(2009) Yu-Chia Chen et al.   HISTOCHEMISTRY AND CELL BIOLOGY

A role for ubiquitin ligases and Spartin/SPG20 in lipid droplet turnover

(2009) Scott W. Eastman et al.   JOURNAL OF CELL BIOLOGY

Hydrophobic and Basic Domains Target Proteins to Lipid Droplets

(2009) Mercedes Ingelmo-Torres et al.   TRAFFIC

The Human Lipodystrophy Gene BSCL2/Seipin May Be Essential for Normal Adipocyte Differentiation

(2008) V. A. Payne et al.   DIABETES

A Block in Endoplasmic Reticulum-to-Golgi Trafficking Inhibits Phospholipid Synthesis and Induces Neutral Lipid Accumulation

(2008) Maria L. Gaspar et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Fld1p, a functional homologue of human seipin, regulates the size of lipid droplets in yeast

(2008) Weihua Fei et al.   JOURNAL OF CELL BIOLOGY

Characterization of seipin/BSCL2, a protein associated with spastic paraplegia 17

(2008) Daisuke Ito et al.   NEUROBIOLOGY OF DISEASE