Elevated NADPH oxidase activity contributes to oxidative stress and cell death in Huntington's disease

The NOX toolbox: validating the role of NADPH oxidases in physiology and disease

(2012) Sebastian Altenhöfer et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

NADPH oxidase-mediated Rac1 GTP activity is necessary for nongenomic actions of the mineralocorticoid receptor in the CA1 region of the rat hippocampus

(2011) Fumiko Kawakami-Mori et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

NADPH Oxidase 1-Mediated Oxidative Stress Leads to Dopamine Neuron Death in Parkinson's Disease

(2011) Dong-Hee Choi et al.   ANTIOXIDANTS & REDOX SIGNALING

Dendritic spine loss and neurodegeneration is rescued by Rab11 in models of Huntington's disease

(2011) P Richards et al.   CELL DEATH AND DIFFERENTIATION

NADPH oxidase-mediated oxidative damage to proteins in the postsynaptic density after transient cerebral ischemia and reperfusion

(2011) Kazutoshi Murotomi et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

Reagents that block neuronal death from Huntington’s disease also curb oxidative stress

(2011) Antonio Valencia et al.   NEUROREPORT

Evidence of Oxidant Damage in Huntington's Disease: Translational Strategies Using Antioxidants

(2010) Edward C. Stack et al.   Annals of the New York Academy of Sciences

Oxidative Stress in Ischemic Brain Damage: Mechanisms of Cell Death and Potential Molecular Targets for Neuroprotection

(2010) Hai Chen et al.   ANTIOXIDANTS & REDOX SIGNALING

Nox4-dependent H2O2 production contributes to chronic glutamate toxicity in primary cortical neurons

(2010) Jong Seong Ha et al.   EXPERIMENTAL CELL RESEARCH

Nadph Oxidase Mediates Striatal Neuronal Injury after Transient Global Cerebral Ischemia

(2010) Hideyuki Yoshioka et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Gp91phox (NOX2) in classically activated microglia exacerbates traumatic brain injury

(2010) Kenji Dohi et al.   Journal of Neuroinflammation

Aberrant Rab11-Dependent Trafficking of the Neuronal Glutamate Transporter EAAC1 Causes Oxidative Stress and Cell Death in Huntington's Disease

(2010) X. Li et al.   JOURNAL OF NEUROSCIENCE

The NADPH Oxidase NOX2 Controls Glutamate Release: A Novel Mechanism Involved in Psychosis-Like Ketamine Responses

(2010) S. Sorce et al.   JOURNAL OF NEUROSCIENCE

Reactive oxygen species generated by NADPH oxidase are involved in neurodegeneration in the pilocarpine model of temporal lobe epilepsy

(2010) Rafaela R.F. Pestana et al.   NEUROSCIENCE LETTERS

NADPH oxidase 2-derived reactive oxygen species in spinal cord microglia contribute to peripheral nerve injury-induced neuropathic pain

(2010) D. Kim et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The many roles of NOX2 NADPH oxidase-derived ROS in immunity

(2010) Grace Y. Lam et al.   Seminars in Immunopathology

Post-Stroke Inhibition of Induced NADPH Oxidase Type 4 Prevents Oxidative Stress and Neurodegeneration

(2010) Christoph Kleinschnitz et al.   PLOS BIOLOGY

Protein Targets of Oxidative Damage in Human Neurodegenerative Diseases with Abnormal Protein Aggregates

(2009) Anna Martínez et al.   BRAIN PATHOLOGY

Effects of paraquat-induced oxidative stress on the neuronal plasma membrane Ca2+-ATPase

(2009) Asma Zaidi et al.   FREE RADICAL BIOLOGY AND MEDICINE

Polyglutamine expansion in huntingtin alters its interaction with phospholipids

(2009) Kimberly B. Kegel et al.   JOURNAL OF NEUROCHEMISTRY

Alterations in Cortical Excitation and Inhibition in Genetic Mouse Models of Huntington's Disease

(2009) D. M. Cummings et al.   JOURNAL OF NEUROSCIENCE

Mutant huntingtin and glycogen synthase kinase 3-β accumulate in neuronal lipid rafts of a presymptomatic knock-in mouse model of Huntington's disease

(2009) Antonio Valencia et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Reactive oxygen species are NOXious for neurons

(2009) Nicolas Demaurex et al.   NATURE NEUROSCIENCE

NADPH oxidase is the primary source of superoxide induced by NMDA receptor activation

(2009) Angela M Brennan et al.   NATURE NEUROSCIENCE

IL-6 Mediated Degeneration of Forebrain GABAergic Interneurons and Cognitive Impairment in Aged Mice through Activation of Neuronal NADPH Oxidase

(2009) Laura L. Dugan et al.   PLoS One

Voltage-gated proton channels

(2008) T. E. DeCoursey   CELLULAR AND MOLECULAR LIFE SCIENCES

Reactive oxygen species regulate F-actin dynamics in neuronal growth cones and neurite outgrowth

(2008) Vidhya Munnamalai et al.   JOURNAL OF NEUROCHEMISTRY

Hyperoxia Causes Maturation-Dependent Cell Death in the Developing White Matter

(2008) B. Gerstner et al.   JOURNAL OF NEUROSCIENCE

Clustering of plasma membrane-bound cytochrome b5 reductase within ‘lipid raft’ microdomains of the neuronal plasma membrane

(2008) Alejandro K. Samhan-Arias et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

Glucose metabolism inhibits apoptosis in neurons and cancer cells by redox inactivation of cytochrome c

(2008) Allyson E. Vaughn et al.   NATURE CELL BIOLOGY

Extensive early motor and non-motor behavioral deficits are followed by striatal neuronal loss in knock-in Huntington's disease mice

(2008) M.A. Hickey et al.   NEUROSCIENCE

A Role for Oxidized DNA Precursors in Huntington's Disease–Like Striatal Neurodegeneration

(2008) Gabriele De Luca et al.   PLoS Genetics