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Aberrant Overexpression of Pyruvate Kinase M2 Is Associated With Aggressive Tumor Features and theBRAFMutation in Papillary Thyroid Cancer

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Pharmacologic Activation of PKM2 Slows Lung Tumor Xenograft Growth

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(2012) Patrick S. Ward et al.   CANCER CELL

PKM2 Phosphorylates Histone H3 and Promotes Gene Transcription and Tumorigenesis

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Increased LDH5 expression is associated with lymph node metastasis and outcome in oral squamous cell carcinoma

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Pyruvate Kinase M2 Regulates Gene Transcription by Acting as a Protein Kinase

(2012) Xueliang Gao et al.   MOLECULAR CELL

ERK1/2-dependent phosphorylation and nuclear translocation of PKM2 promotes the Warburg effect

(2012) Weiwei Yang et al.   NATURE CELL BIOLOGY

Differential Expression of Metabolic Genes in Tumor and Stromal Components of Primary and Metastatic Loci in Pancreatic Adenocarcinoma

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M2 isoform of pyruvate kinase is dispensable for tumor maintenance and growth

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Yes-associated protein promotes cell proliferation by activating Fos Related Activator-1 in oral squamous cell carcinoma

(2011) Lei Zhang et al.   ORAL ONCOLOGY

Comparative Proteomic Approach Identifies Pkm2 and Cofilin-1 as Potential Diagnostic, Prognostic and Therapeutic Targets for Pulmonary Adenocarcinoma

(2011) Xing-chen Peng et al.   PLoS One

Mammalian target of rapamycin up-regulation of pyruvate kinase isoenzyme type M2 is critical for aerobic glycolysis and tumor growth

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Inhibition of lactate dehydrogenase A induces oxidative stress and inhibits tumor progression

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Upregulation of vimentin and aberrant expression of E-cadherin/β-catenin complex in oral squamous cell carcinomas: correlation with the clinicopathological features and patient outcome

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Lactate Dehydrogenase 5 Expression in Squamous Cell Head and Neck Cancer Relates to Prognosis following Radical or Postoperative Radiotherapy

(2009) Michael I. Koukourakis et al.   ONCOLOGY

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(2009) Crispian Scully et al.   ORAL ONCOLOGY

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(2009) Alexander D. Rapidis et al.   ORAL ONCOLOGY

Understanding the Warburg Effect: The Metabolic Requirements of Cell Proliferation

(2009) M. G. Vander Heiden et al.   SCIENCE

Lactate Dehydrogenase-5 (LDH-5) Expression in Human Gastric Cancer: Association with Hypoxia-Inducible Factor (HIF-1α) Pathway, Angiogenic Factors Production and Poor Prognosis

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Characteristics of a cancerous cell line, HIOEC-B(a)P-96, induced by benzo(a)pyrene from human immortalized oral epithelial cell line

(2008) Lai-Ping Zhong et al.   ARCHIVES OF ORAL BIOLOGY

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(2008) Thian-Sze Wong et al.   INTERNATIONAL JOURNAL OF CANCER

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