Osteopontin: Versatile modulator of liver diseases

Postoperative Serum Osteopontin Level is a Novel Monitor for Treatment Response and Tumor Recurrence after Resection of Hepatitis B–related Hepatocellular Carcinoma

(2012) Chuang Zhou et al.   ANNALS OF SURGICAL ONCOLOGY

Natural killer and natural killer T cells in liver fibrosis

(2012) Bin Gao et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

NKT-associated hedgehog and osteopontin drive fibrogenesis in non-alcoholic fatty liver disease

(2012) Wing-Kin Syn et al.   GUT

Osteopontin is a novel downstream target of SOX9 with diagnostic implications for progression of liver fibrosis in humans

(2012) James Pritchett et al.   HEPATOLOGY

Osteopontin promoter polymorphisms at locus -443 significantly affect the metastasis and prognosis of human hepatocellular carcinoma

(2012) Qiong-Zhu Dong et al.   HEPATOLOGY

Single-nucleotide polymorphism in the promoter region of the osteopontin gene at nucleotide −443 as a marker predicting the efficacy of pegylated interferon/ribavirin-therapy in Egyptians patients with chronic hepatitis C

(2012) Olfat Gamil Shaker et al.   HUMAN IMMUNOLOGY

The Osteopontin Level in Liver, Adipose Tissue and Serum Is Correlated with Fibrosis in Patients with Alcoholic Liver Disease

(2012) Stéphanie Patouraux et al.   PLoS One

Osteopontin increases hepatocellular carcinoma cell growth in a CD44 dependant manner

(2012) Renee J Phillips   WORLD JOURNAL OF GASTROENTEROLOGY

Osteopontin deficiency protects against obesity-induced hepatic steatosis and attenuates glucose production in mice

(2011) F. W. Kiefer et al.   DIABETOLOGIA

Identification of osteopontin as a novel marker for early hepatocellular carcinoma

(2011) Sufen Shang et al.   HEPATOLOGY

Prognostic significance of osteopontin in hepatocellular carcinoma: A meta-analysis

(2011) Chuan-Hai Zhang et al.   INTERNATIONAL JOURNAL OF CANCER

Increased production of sonic hedgehog by ballooned hepatocytes

(2011) Fatima Rangwala et al.   JOURNAL OF PATHOLOGY

Specific expression of osteopontin and S100A6 in hepatocellular carcinoma

(2011) Zhan Hua et al.   SURGERY

A bispecific antibody effectively inhibits tumor growth and metastasis by simultaneous blocking vascular endothelial growth factor A and osteopontin

(2010) Geng Kou et al.   CANCER LETTERS

Expression and prognostic significance of osteopontin and caspase-3 in hepatocellular carcinoma patients after curative resection

(2010) Hua Huang et al.   CANCER SCIENCE

Plasma osteopontin concentration correlates with the severity of hepatic fibrosis and inflammation in HCV-infected subjects

(2010) Wenbao Huang et al.   CLINICA CHIMICA ACTA

Enhanced expression of pro-inflammatory mediators and liver X-receptor-regulated lipogenic genes in non-alcoholic fatty liver disease and hepatitis C

(2010) Elena Lima-Cabello et al.   CLINICAL SCIENCE

Osteopontin: An Effector and an Effect of Tumor Metastasis

(2010) L. Shevde et al.   CURRENT MOLECULAR MEDICINE

Neutralization of Osteopontin Inhibits Obesity-Induced Inflammation and Insulin Resistance

(2010) F. W. Kiefer et al.   DIABETES

Accumulation of natural killer T cells in progressive nonalcoholic fatty liver disease

(2010) Wing-Kin Syn et al.   HEPATOLOGY

Osteopontin is induced by hedgehog pathway activation and promotes fibrosis progression in nonalcoholic steatohepatitis

(2010) Wing-Kin Syn et al.   HEPATOLOGY

Cyclooxygenase-2 gene promoter polymorphisms affect susceptibility to hepatitis C virus infection and disease progression

(2010) Masashi Sakaki et al.   HEPATOLOGY RESEARCH

Intracellular osteopontin (iOPN) and immunity

(2010) Makoto Inoue et al.   IMMUNOLOGIC RESEARCH

The role of Hedgehog signaling in fibrogenic liver repair

(2010) Steve S. Choi et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Osteopontin Is Cleaved at Multiple Sites Close to Its Integrin-binding Motifs in Milk and Is a Novel Substrate for Plasmin and Cathepsin D

(2010) Brian Christensen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Osteopontin expression predicts overall survival after liver transplantation for hepatocellular carcinoma in patients beyond the Milan criteria

(2010) Wolfgang Sieghart et al.   JOURNAL OF HEPATOLOGY

Osteopontin promotes hepatocellular carcinoma invasion by up-regulating MMP-2 and uPA expression

(2010) Rong-Xin Chen et al.   MOLECULAR BIOLOGY REPORTS

Hedgehog-Mediated Epithelial-to-Mesenchymal Transition and Fibrogenic Repair in Nonalcoholic Fatty Liver Disease

(2009) Wing–Kin Syn et al.   GASTROENTEROLOGY

Genomic aberrations in hepatocellular carcinoma related to osteopontin expression detected by array-CGH

(2009) Jin-Cai Wu et al.   JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY

The prognostic significance of preoperative plasma levels of osteopontin in patients with TNM stage-I of hepatocellular carcinoma

(2009) Jian Sun et al.   JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY

Elevated Expression of Osteopontin May Be Related to Adipose Tissue Macrophage Accumulation and Liver Steatosis in Morbid Obesity

(2008) A. Bertola et al.   DIABETES

Down-Regulation of Osteopontin Suppresses Growth and Metastasis of Hepatocellular Carcinoma Via Induction of Apoptosis

(2008) Jian Zhao et al.   GASTROENTEROLOGY

Lentiviral-mediated miRNA against osteopontin suppresses tumor growth and metastasis of human hepatocellular carcinoma

(2008) Bing-Sheng Sun et al.   HEPATOLOGY

Overexpression of osteopontin independently correlates with vascular invasion and poor prognosis in patients with hepatocellular carcinoma

(2008) Pavel V. Korita et al.   HUMAN PATHOLOGY