Fattyaciddesaturase 1gene polymorphisms control human hepatic lipid composition

Mapping of hepatic expression quantitative trait loci (eQTLs) in a Han Chinese population

(2014) Xiaoliang Wang et al.   JOURNAL OF MEDICAL GENETICS

Omega-3 fatty acids for treatment of non-alcoholic fatty liver disease: design and rationale of randomized controlled trial

(2013) Wojciech Janczyk et al.   BMC Pediatrics

A gene variant ofPNPLA3, but not ofAPOC3, is associated with histological parameters of NAFLD in an obese population

(2013) A. Verrijken et al.   Obesity

A Case-Control Study between Gene Polymorphisms of Polyunsaturated Fatty Acid Metabolic Rate-Limiting Enzymes and Acute Coronary Syndrome in Chinese Han Population

(2013) Zikai Song et al.   Biomed Research International

SNPs affecting serum metabolomic traits may regulate gene transcription and lipid accumulation in the liver

(2012) Snezana Mirkov et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

Genome-Wide Association Study Identifies Novel Loci Associated with Circulating Phospho- and Sphingolipid Concentrations

(2012) Ayşe Demirkan et al.   PLoS Genetics

Docosahexaenoic acid supplementation decreases liver fat content in children with non-alcoholic fatty liver disease: double-blind randomised controlled clinical trial

(2011) V. Nobili et al.   ARCHIVES OF DISEASE IN CHILDHOOD

Genetic variants in the metabolism of omega-6 and omega-3 fatty acids: their role in the determination of nutritional requirements and chronic disease risk

(2011) Artemis P Simopoulos   EXPERIMENTAL BIOLOGY AND MEDICINE

NASH: A global health problem

(2011) Arun J. Sanyal   HEPATOLOGY RESEARCH

Genome-wide association study identifies loci influencing concentrations of liver enzymes in plasma

(2011) John C Chambers et al.   NATURE GENETICS

Identification, Replication, and Functional Fine-Mapping of Expression Quantitative Trait Loci in Primary Human Liver Tissue

(2011) Federico Innocenti et al.   PLoS Genetics

Genetic Loci Associated with Plasma Phospholipid n-3 Fatty Acids: A Meta-Analysis of Genome-Wide Association Studies from the CHARGE Consortium

(2011) Rozenn N. Lemaitre et al.   PLoS Genetics

FADS1 FADS2 gene variants modify the association between fish intake and the docosahexaenoic acid proportions in human milk

(2010) Carolina Moltó-Puigmartí et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Genetic variants of the FADS1 FADS2 gene cluster as related to essential fatty acid metabolism

(2010) Eva Lattka et al.   CURRENT OPINION IN LIPIDOLOGY

Comparing morphometric, biochemical, and visual measurements of macrovesicular steatosis of liver☆☆☆

(2010) Mei Li et al.   HUMAN PATHOLOGY

Lipid Profiling Reveals Tissue-Specific Differences for Ethanolamide Lipids in Mice Lacking Fatty Acid Amide Hydrolase

(2010) Aruna Kilaru et al.   LIPIDS

Genetic variation in lipid desaturases and its impact on the development of human disease

(2010) Diana M Merino et al.   Lipids in Health and Disease

Role of FADS1 and FADS2 polymorphisms in polyunsaturated fatty acid metabolism

(2010) Claudia Glaser et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

FADS2 Polymorphisms Modify the Effect of Breastfeeding on Child IQ

(2010) Colin D. Steer et al.   PLoS One

Variants of the FADS1 FADS2 Gene Cluster, Blood Levels of Polyunsaturated Fatty Acids and Eczema in Children within the First 2 Years of Life

(2010) Peter Rzehak et al.   PLoS One

Quantitative contributions of diet and liver synthesis to docosahexaenoic acid homeostasis

(2010) Stanley I. Rapoport et al.   PROSTAGLANDINS LEUKOTRIENES AND ESSENTIAL FATTY ACIDS

Does genetic variation in the Δ6-desaturase promoter modify the association between α-linolenic acid and the prevalence of metabolic syndrome?

(2009) Hong Truong et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Do FADS genotypes enhance our knowledge about fatty acid related phenotypes?

(2009) Eva Lattka et al.   CLINICAL NUTRITION

A genome-wide perspective of genetic variation in human metabolism

(2009) Thomas Illig et al.   NATURE GENETICS

Decreased Liver Fatty Acid Δ-6 and Δ-5 Desaturase Activity in Obese Patients

(2009) Julia Araya et al.   Obesity

Genome-Wide Association Study of Plasma Polyunsaturated Fatty Acids in the InCHIANTI Study

(2009) Toshiko Tanaka et al.   PLoS Genetics

Dietary Phosphatidylinositol Prevents the Development of Nonalcoholic Fatty Liver Disease in Zucker (fa/fa) Rats

(2008) Bungo Shirouchi et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Genetic Variants of the FADS1 FADS2 Gene Cluster Are Associated with Altered (n-6) and (n-3) Essential Fatty Acids in Plasma and Erythrocyte Phospholipids in Women during Pregnancy and in Breast Milk during Lactation

(2008) Lin Xie et al.   JOURNAL OF NUTRITION

SNPs of the FADS Gene Cluster are Associated with Polyunsaturated Fatty Acids in a Cohort of Patients with Cardiovascular Disease

(2008) Giovanni Malerba et al.   LIPIDS

Genetic variation in PNPLA3 confers susceptibility to nonalcoholic fatty liver disease

(2008) Stefano Romeo et al.   NATURE GENETICS

Genome-wide association analysis of metabolic traits in a birth cohort from a founder population

(2008) Chiara Sabatti et al.   NATURE GENETICS

Lower estimates of δ-5 desaturase and elongase activity are related to adverse profiles for several metabolic risk factors in young Japanese women

(2008) Kentaro Murakami et al.   NUTRITION RESEARCH

Genetics Meets Metabolomics: A Genome-Wide Association Study of Metabolite Profiles in Human Serum

(2008) Christian Gieger et al.   PLoS Genetics

Effects of n-3 polyunsaturated fatty acids in subjects with nonalcoholic fatty liver disease

(2007) L. Spadaro et al.   DIGESTIVE AND LIVER DISEASE

Nutritional assessment and hepatic fatty acid composition in non-alcoholic fatty liver disease (NAFLD): A cross-sectional study

(2007) Johane P. Allard et al.   JOURNAL OF HEPATOLOGY