Glucose sensing O-GlcNAcylation pathway regulates the nuclear bile acid receptor farnesoid X receptor (FXR)

Farnesoid X Receptor Inhibits the Transcriptional Activity of Carbohydrate Response Element Binding Protein in Human Hepatocytes

(2013) S. Caron et al.   MOLECULAR AND CELLULAR BIOLOGY

O-GlcNAc Transferase/Host Cell Factor C1 Complex Regulates Gluconeogenesis by Modulating PGC-1α Stability

(2012) Hai-Bin Ruan et al.   Cell Metabolism

Genomic analysis of hepatic farnesoid X receptor binding sites reveals altered binding in obesity and direct gene repression by farnesoid X receptor in mice

(2012) Jiyoung Lee et al.   HEPATOLOGY

O-GlcNAc Transferase Is Involved in Glucocorticoid Receptor-mediated Transrepression

(2012) Min-Dian Li et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Evidence of the Involvement ofO-GlcNAc-modified Human RNA Polymerase II CTD in Transcriptionin Vitroandin Vivo

(2012) Stella M. Ranuncolo et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

TET2 promotes histone O-GlcNAcylation during gene transcription

(2012) Qiang Chen et al.   NATURE

linking metabolism to epigenetics through O-GlcNAcylation

(2012) John A. Hanover et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

The human hepatocyte cell lines IHH and HepaRG: models to study glucose, lipid and lipoprotein metabolism

(2012) Carolina Huaman Samanez et al.   ARCHIVES OF PHYSIOLOGY AND BIOCHEMISTRY

Cross Talk Between O-GlcNAcylation and Phosphorylation: Roles in Signaling, Transcription, and Chronic Disease

(2011) Gerald W. Hart et al.   Annual Review of Biochemistry

O-GlcNAc modification of PPARγ reduces its transcriptional activity

(2011) Suena Ji et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Bile acid signaling after an oral glucose tolerance test

(2011) Silke Matysik et al.   CHEMISTRY AND PHYSICS OF LIPIDS

Farnesoid X Receptor Deficiency Improves Glucose Homeostasis in Mouse Models of Obesity

(2011) J. Prawitt et al.   DIABETES

Modulation of transcription factor function by O-GlcNAc modification

(2010) Sabire Özcan et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

O-GlcNAc signaling: a metabolic link between diabetes and cancer?

(2010) C. Slawson et al.   TRENDS IN BIOCHEMICAL SCIENCES

FXR Acetylation Is Normally Dynamically Regulated by p300 and SIRT1 but Constitutively Elevated in Metabolic Disease States

(2009) Jongsook Kim Kemper et al.   Cell Metabolism

Nuclear Receptor Liver X Receptor IsO-GlcNAc-modified in Response to Glucose

(2009) Elin Holter Anthonisen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Discovery of XL335 (WAY-362450), a Highly Potent, Selective, and Orally Active Agonist of the Farnesoid X Receptor (FXR)

(2009) Brenton Flatt et al.   JOURNAL OF MEDICINAL CHEMISTRY

Role of Bile Acids and Bile Acid Receptors in Metabolic Regulation

(2009) Philippe Lefebvre et al.   PHYSIOLOGICAL REVIEWS

Protein ubiquitination is modulated by O-GlcNAc glycosylation

(2008) Céline Guinez et al.   FASEB JOURNAL

O-Linked β-N-Acetylglucosaminyltransferase Substrate Specificity Is Regulated by Myosin Phosphatase Targeting and Other Interacting Proteins

(2008) Win D. Cheung et al.   JOURNAL OF BIOLOGICAL CHEMISTRY