Identification of driver genes in hepatocellular carcinoma by exome sequencing

Mixed lineage leukaemia-4 regulates cell-cycle progression and cell viability and its depletion suppresses growth of xenografted tumour in vivo

(2012) K I Ansari et al.   BRITISH JOURNAL OF CANCER

Marked, Homogeneous, and Early [18F]Fluorodeoxyglucose–Positron Emission Tomography Responses to Vemurafenib in BRAF-Mutant Advanced Melanoma

(2012) Grant A. McArthur et al.   JOURNAL OF CLINICAL ONCOLOGY

Sequence analysis of mutations and translocations across breast cancer subtypes

(2012) Shantanu Banerji et al.   NATURE

Exome sequencing of hepatitis B virus–associated hepatocellular carcinoma

(2012) Jian Huang et al.   NATURE GENETICS

Whole-genome sequencing of liver cancers identifies etiological influences on mutation patterns and recurrent mutations in chromatin regulators

(2012) Akihiro Fujimoto et al.   NATURE GENETICS

Genome-wide survey of recurrent HBV integration in hepatocellular carcinoma

(2012) Wing-Kin Sung et al.   NATURE GENETICS

Integrated analysis of somatic mutations and focal copy-number changes identifies key genes and pathways in hepatocellular carcinoma

(2012) Cécile Guichard et al.   NATURE GENETICS

Fast gapped-read alignment with Bowtie 2

(2012) Ben Langmead et al.   NATURE METHODS

Molecularly Targeted Therapy for Advanced Hepatocellular Carcinoma in 2012: Current Status and Future Perspectives

(2012) Andrew X. Zhu   SEMINARS IN ONCOLOGY

Targeted Therapies for Hepatocellular Carcinoma

(2011) Augusto Villanueva et al.   GASTROENTEROLOGY

Molecular mechanisms of the Keap1-Nrf2 pathway in stress response and cancer evolution

(2011) Keiko Taguchi et al.   GENES TO CELLS

Strategies for hepatocellular carcinoma therapy and diagnostics: Lessons learned from high throughput and profiling approaches

(2011) Kai Breuhahn et al.   HEPATOLOGY

Initial genome sequencing and analysis of multiple myeloma

(2011) Michael A. Chapman et al.   NATURE

High-resolution characterization of a hepatocellular carcinoma genome

(2011) Yasushi Totoki et al.   NATURE GENETICS

Inactivating mutations of the chromatin remodeling gene ARID2 in hepatocellular carcinoma

(2011) Meng Li et al.   NATURE GENETICS

A framework for variation discovery and genotyping using next-generation DNA sequencing data

(2011) Mark A DePristo et al.   NATURE GENETICS

Rapid growth of a hepatocellular carcinoma and the driving mutations revealed by cell-population genetic analysis of whole-genome data

(2011) Y. Tao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Genetics of Hepatobiliary Carcinogenesis

(2011) Jean-Charles Nault et al.   SEMINARS IN LIVER DISEASE

Chromosome 1q21 amplification and oncogenes in hepatocellular carcinoma

(2010) Leilei Chen et al.   ACTA PHARMACOLOGICA SINICA

Association of TP53 Mutations With Stem Cell-Like Gene Expression and Survival of Patients With Hepatocellular Carcinoma

(2010) Hyun Goo Woo et al.   GASTROENTEROLOGY

The Genome Analysis Toolkit: A MapReduce framework for analyzing next-generation DNA sequencing data

(2010) A. McKenna et al.   GENOME RESEARCH

Physical and Functional Interaction of Sequestosome 1 with Keap1 Regulates the Keap1-Nrf2 Cell Defense Pathway

(2010) Ian M. Copple et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cancer gene discovery in hepatocellular carcinoma

(2010) Lars Zender et al.   JOURNAL OF HEPATOLOGY

genenames.org: the HGNC resources in 2011

(2010) R. L. Seal et al.   NUCLEIC ACIDS RESEARCH

ANNOVAR: functional annotation of genetic variants from high-throughput sequencing data

(2010) K. Wang et al.   NUCLEIC ACIDS RESEARCH

COSMIC: mining complete cancer genomes in the Catalogue of Somatic Mutations in Cancer

(2010) S. A. Forbes et al.   NUCLEIC ACIDS RESEARCH

Gefitinib or Carboplatin–Paclitaxel in Pulmonary Adenocarcinoma

(2009) Tony S. Mok et al.   NEW ENGLAND JOURNAL OF MEDICINE

Nitric oxide activation of Keap1/Nrf2 signaling in human colon carcinoma cells

(2009) C.-Q. Li et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A tumor suppressive coactivator complex of p53 containing ASC-2 and histone H3-lysine-4 methyltransferase MLL3 or its paralogue MLL4

(2009) J. Lee et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Focal Gains of VEGFA and Molecular Classification of Hepatocellular Carcinoma

(2008) D. Y. Chiang et al.   CANCER RESEARCH

Somatic mutations affect key pathways in lung adenocarcinoma

(2008) Li Ding et al.   NATURE

Gene Expression in Fixed Tissues and Outcome in Hepatocellular Carcinoma

(2008) Yujin Hoshida et al.   NEW ENGLAND JOURNAL OF MEDICINE