Strategies for hepatocellular carcinoma therapy and diagnostics: Lessons learned from high throughput and profiling approaches

Management of hepatocellular carcinoma: An update

(2011) Jordi Bruix et al.   HEPATOLOGY

Identification of Aneuploidy-Tolerating Mutations

(2010) Eduardo M. Torres et al.   CELL

Radioembolization Results in Longer Time-to-Progression and Reduced Toxicity Compared With Chemoembolization in Patients With Hepatocellular Carcinoma

(2010) Riad Salem et al.   GASTROENTEROLOGY

The MicroRNA miR-139 Suppresses Metastasis and Progression of Hepatocellular Carcinoma by Down-regulating Rho-Kinase 2

(2010) Carmen Chak–Lui Wong et al.   GASTROENTEROLOGY

Sorafenib: Where do we go from here?

(2010) Abby B. Siegel et al.   HEPATOLOGY

MicroRNA-125b suppressesed human liver cancer cell proliferation and metastasis by directly targeting oncogene LIN28B2

(2010) Linhui Liang et al.   HEPATOLOGY

Differential Proteomics Identification of HSP90 as Potential Serum Biomarker in Hepatocellular Carcinoma by Two-dimensional Electrophoresis and Mass Spectrometry

(2010) Yiyi Sun et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Defective Mismatch Repair As a Predictive Marker for Lack of Efficacy of Fluorouracil-Based Adjuvant Therapy in Colon Cancer

(2010) Daniel J. Sargent et al.   JOURNAL OF CLINICAL ONCOLOGY

The platinum-based treatments for advanced non-small cell lung cancer, is low/negative ERCC1 expression better than high/positive ERCC1 expression? A meta-analysis

(2010) Sufeng Chen et al.   LUNG CANCER

TAp63 suppresses metastasis through coordinate regulation of Dicer and miRNAs

(2010) Xiaohua Su et al.   NATURE

International network of cancer genome projects

(2010) Thomas J. Hudson (Chairperson) et al.   NATURE

Epigenetic methylation and expression of caspase 8 and survivin in hepatocellular carcinoma

(2010) Seok Cho et al.   PATHOLOGY INTERNATIONAL

Hepatocellular Carcinoma Displays Distinct DNA Methylation Signatures with Potential as Clinical Predictors

(2010) Hector Hernandez-Vargas et al.   PLoS One

The Tumor Suppressors p53, p63, and p73 Are Regulators of MicroRNA Processing Complex

(2010) Lakshmanane Boominathan   PLoS One

Stem cell-like micro-RNA signature driven by Myc in aggressive liver cancer

(2010) S. Cairo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Yes-associated protein is an independent prognostic marker in hepatocellular carcinoma

(2009) Michelle Z. Xu et al.   CANCER

Identification of Potential Driver Genes in Human Liver Carcinoma by Genomewide Screening

(2009) H. G. Woo et al.   CANCER RESEARCH

Integrative Transcriptome Analysis Reveals Common Molecular Subclasses of Human Hepatocellular Carcinoma

(2009) Y. Hoshida et al.   CANCER RESEARCH

Optimizing Trial Design

(2009) Cyrus Mehta et al.   CIRCULATION

I-SPY 2: An Adaptive Breast Cancer Trial Design in the Setting of Neoadjuvant Chemotherapy

(2009) AD Barker et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Overexpression of far upstream element binding proteins: A mechanism regulating proliferation and migration in liver cancer cells

(2009) Mona Malz et al.   HEPATOLOGY

Identification of microRNA-181 by genome-wide screening as a critical player in EpCAM-positive hepatic cancer stem cells

(2009) Junfang Ji et al.   HEPATOLOGY

Targeting cadherin-17 inactivates Wnt signaling and inhibits tumor growth in liver carcinoma

(2009) Ling Xiao Liu et al.   HEPATOLOGY

Targeting heat shock protein 90 with non-quinone inhibitors: A novel chemotherapeutic approach in human hepatocellular carcinoma

(2009) Marco Breinig et al.   HEPATOLOGY

Genome-wide DNA methylation profiles in liver tissue at the precancerous stage and in hepatocellular carcinoma

(2009) Eri Arai et al.   INTERNATIONAL JOURNAL OF CANCER

Oncolytic virotherapy for advanced liver tumours

(2009) Ju-Fang Chang et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

MicroRNA Expression, Survival, and Response to Interferon in Liver Cancer

(2009) Junfang Ji et al.   NEW ENGLAND JOURNAL OF MEDICINE

miR-221 overexpression contributes to liver tumorigenesis

(2009) P. Pineau et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Drug resistance associated with antiangiogenesis therapy

(2009) Hans Petter Eikesdal et al.   SEMINARS IN CANCER BIOLOGY

Investigating the correspondence between transcriptomic and proteomic expression profiles using coupled cluster models

(2008) Simon Rogers et al.   BIOINFORMATICS

Common dysregulation of Wnt/Frizzled receptor elements in human hepatocellular carcinoma

(2008) A Bengochea et al.   BRITISH JOURNAL OF CANCER

Hepatitis B Virus-Associated Multistep Hepatocarcinogenesis: A Stepwise Increase in Allelic Alterations

(2008) J. M.-F. Lee et al.   CANCER RESEARCH

Focal Gains of VEGFA and Molecular Classification of Hepatocellular Carcinoma

(2008) D. Y. Chiang et al.   CANCER RESEARCH

Association of MicroRNA Expression in Hepatocellular Carcinomas with Hepatitis Infection, Cirrhosis, and Patient Survival

(2008) J. Jiang et al.   CLINICAL CANCER RESEARCH

MicroRNA-223 Is Commonly Repressed in Hepatocellular Carcinoma and Potentiates Expression of Stathmin1

(2008) Queenie W.–L. Wong et al.   GASTROENTEROLOGY

Pivotal Role of mTOR Signaling in Hepatocellular Carcinoma

(2008) Augusto Villanueva et al.   GASTROENTEROLOGY

Most mammalian mRNAs are conserved targets of microRNAs

(2008) R. C. Friedman et al.   GENOME RESEARCH

Autocrine insulin-like growth factor-II stimulation of tumor cell migration is a progression step in human hepatocarcinogenesis

(2008) Tanja Nussbaum et al.   HEPATOLOGY

Pathologic diagnosis of early hepatocellular carcinoma: A report of the international consensus group for hepatocellular neoplasia

(2008)   HEPATOLOGY

Identification of metastasis-related microRNAs in hepatocellular carcinoma

(2008) Anuradha Budhu et al.   HEPATOLOGY

Differential microRNA expression between hepatitis B and hepatitis C leading disease progression to hepatocellular carcinoma

(2008) Shunsuke Ura et al.   HEPATOLOGY

MicroRNA profiling in hepatocellular tumors is associated with clinical features and oncogene/tumor suppressor gene mutations

(2008) Yannick Ladeiro et al.   HEPATOLOGY

Clinical implication of recurrent copy number alterations in hepatocellular carcinoma and putative oncogenes in recurrent gains on 1q

(2008) Tae-Min Kim et al.   INTERNATIONAL JOURNAL OF CANCER

Experimental models of hepatocellular carcinoma

(2008) Philippa Newell et al.   JOURNAL OF HEPATOLOGY

Design and Endpoints of Clinical Trials in Hepatocellular Carcinoma

(2008) Josep M. Llovet et al.   JNCI-Journal of the National Cancer Institute

Prevention of hepatitis B virus infection in vivo by entry inhibitors derived from the large envelope protein

(2008) Joerg Petersen et al.   NATURE BIOTECHNOLOGY

Sorafenib in Advanced Hepatocellular Carcinoma

(2008) Josep M. Llovet et al.   NEW ENGLAND JOURNAL OF MEDICINE

MicroRNA-373 induces expression of genes with complementary promoter sequences

(2008) R. F. Place et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Core Signaling Pathways in Human Pancreatic Cancers Revealed by Global Genomic Analyses

(2008) S. Jones et al.   SCIENCE