Therapeutic effect of cytotoxic T lymphocyte antigen 4/immunoglobulin on a murine model of primary biliary cirrhosis

Epitope-specific anti-nuclear antibodies are expressed in a mouse model of primary biliary cirrhosis and are cytokine-dependent

(2012) C-Y. Yang et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Immune checkpoints in central nervous system autoimmunity

(2012) Nicole Joller et al.   IMMUNOLOGICAL REVIEWS

Treatment of active ankylosing spondylitis with abatacept: an open-label, 24-week pilot study

(2011) I.-H. Song et al.   ANNALS OF THE RHEUMATIC DISEASES

The multi-hit hypothesis of primary biliary cirrhosis: polyinosinic-polycytidylic acid (poly I:C) and murine autoimmune cholangitis

(2011) Y. M. Ambrosini et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Intrinsic and extrinsic control of peripheral T-cell tolerance by costimulatory molecules of the CD28/ B7 family

(2011) Hélène Bour-Jordan et al.   IMMUNOLOGICAL REVIEWS

Cell-autonomous and -non-autonomous roles of CTLA-4 in immune regulation

(2011) Kajsa Wing et al.   TRENDS IN IMMUNOLOGY

The efficacy and safety of abatacept in patients with non-life-threatening manifestations of systemic lupus erythematosus: Results of a twelve-month, multicenter, exploratory, phase IIb, randomized, double-blind, placebo-controlled trial

(2010) J. T. Merrill et al.   ARTHRITIS AND RHEUMATISM

Long-term safety and efficacy of abatacept in children with juvenile idiopathic arthritis

(2010) Nicolino Ruperto et al.   ARTHRITIS AND RHEUMATISM

Abatacept in the treatment of patients with psoriatic arthritis: Results of a six-month, multicenter, randomized, double-blind, placebo-controlled, phase II trial

(2010) Philip Mease et al.   ARTHRITIS AND RHEUMATISM

Deletion of interleukin-6 in mice with the dominant negative form of transforming growth factor β receptor II improves colitis but exacerbates autoimmune cholangitis

(2010) Weici Zhang et al.   HEPATOLOGY

Biliary apotopes and anti-mitochondrial antibodies activate innate immune responses in primary biliary cirrhosis

(2010) Ana Lleo et al.   HEPATOLOGY

CD8 T Cells Mediate Direct Biliary Ductule Damage in Nonobese Diabetic Autoimmune Biliary Disease

(2010) G.-X. Yang et al.   JOURNAL OF IMMUNOLOGY

Abatacept treatment for rheumatoid arthritis

(2010) M. Schiff   RHEUMATOLOGY

Deletion of interleukin-12p40 suppresses autoimmune cholangitis in dominant negative transforming growth factor β receptor type II mice

(2009) Katsunori Yoshida et al.   HEPATOLOGY

Mechanisms of costimulation

(2009) Arlene H. Sharpe   IMMUNOLOGICAL REVIEWS

Mode of action of abatacept in rheumatoid arthritis patients having failed tumour necrosis factor blockade: a histological, gene expression and dynamic magnetic resonance imaging pilot study

(2008) M H Buch et al.   ANNALS OF THE RHEUMATIC DISEASES

Induction of autoimmune cholangitis in non-obese diabetic (NOD).1101 mice following a chemical xenobiotic immunization

(2008) K. Wakabayashi et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Adoptive transfer of CD8+ T cells from transforming growth factor beta receptor type II (dominant negative form) induces autoimmune cholangitis in mice

(2008) Guo-Xiang Yang et al.   HEPATOLOGY

Loss of tolerance in C57BL/6 mice to the autoantigen E2 subunit of pyruvate dehydrogenase by a xenobiotic with ensuing biliary ductular disease

(2008) Kanji Wakabayashi et al.   HEPATOLOGY

Abatacept in children with juvenile idiopathic arthritis: a randomised, double-blind, placebo-controlled withdrawal trial

(2008) Nicolino Ruperto et al.   LANCET

Abatacept modulates human dendritic cell-stimulated T-cell proliferation and effector function independent of IDO induction

(2007) Patricia M. Davis et al.   CLINICAL IMMUNOLOGY