Disruption of phospholipid and bile acid homeostasis in mice with nonalcoholic steatohepatitis

Systematic review: the epidemiology and natural history of non-alcoholic fatty liver disease and non-alcoholic steatohepatitis in adults

(2011) G. Vernon et al.   ALIMENTARY PHARMACOLOGY & THERAPEUTICS

Mechanisms of lysophosphatidylcholine-induced hepatocyte lipoapoptosis

(2011) Keisuke Kakisaka et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

A comprehensive understanding of thioTEPA metabolism in the mouse using UPLC–ESI-QTOFMS-based metabolomics

(2011) Fei Li et al.   BIOCHEMICAL PHARMACOLOGY

Lithocholic acid disrupts phospholipid and sphingolipid homeostasis leading to cholestasis in mice

(2011) Tsutomu Matsubara et al.   HEPATOLOGY

Serum metabolomics reveals γ-glutamyl dipeptides as biomarkers for discrimination among different forms of liver disease

(2011) Tomoyoshi Soga et al.   JOURNAL OF HEPATOLOGY

Eicosapentaenoic acid improves hepatic steatosis independent of PPARα activation through inhibition of SREBP-1 maturation in mice

(2010) Naoki Tanaka et al.   BIOCHEMICAL PHARMACOLOGY

Xenobiotic Metabolism: A View through the Metabolometer

(2010) Andrew D. Patterson et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Nonalcoholic fatty liver disease and hepatocellular carcinoma: A weighty connection

(2010) Brad Q. Starley et al.   HEPATOLOGY

Hepatic lipotoxicity and the pathogenesis of nonalcoholic steatohepatitis: The central role of nontriglyceride fatty acid metabolites

(2010) Brent A. Neuschwander-Tetri   HEPATOLOGY

Evolution of inflammation in nonalcoholic fatty liver disease: The multiple parallel hits hypothesis

(2010) Herbert Tilg et al.   HEPATOLOGY

Nonalcoholic fatty liver disease in Japanese junior high school students: its prevalence and relationship to lifestyle habits

(2010) Goro Tsuruta et al.   JOURNAL OF GASTROENTEROLOGY

Down-regulation of SREBP-1c is associated with the development of burned-out NASH

(2010) Tadanobu Nagaya et al.   JOURNAL OF HEPATOLOGY

Blockade of interleukin-6 signaling enhances hepatic steatosis but improves liver injury in methionine choline-deficient diet-fed mice

(2010) Kanji Yamaguchi et al.   LABORATORY INVESTIGATION

Plasma metabolomic profile in nonalcoholic fatty liver disease

(2010) Satish C. Kalhan et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

Serum Metabolomics Reveals Irreversible Inhibition of Fatty Acid β-Oxidation through the Suppression of PPARα Activation as a Contributing Mechanism of Acetaminophen-Induced Hepatotoxicity

(2009) Chi Chen et al.   CHEMICAL RESEARCH IN TOXICOLOGY

The Addition of Choline to Parenteral Nutrition

(2009) Alan L. Buchman   GASTROENTEROLOGY

The natural history of non-alcoholic fatty liver disease in children: a follow-up study for up to 20 years

(2009) A E Feldstein et al.   GUT

Decreased survival of subjects with elevated liver function tests during a 28-year follow-up

(2009) Cecilia Söderberg et al.   HEPATOLOGY

The plasma lipidomic signature of nonalcoholic steatohepatitis

(2009) Puneet Puri et al.   HEPATOLOGY

Polyenephosphatidylcholine prevents alcoholic liver disease in PPARα-null mice through attenuation of increases in oxidative stress

(2009) Wataru Okiyama et al.   JOURNAL OF HEPATOLOGY

The role of osteopontin in d-galactosamine-induced liver injury in genetically obese mice

(2009) Hyo-Jung Kwon et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Hepatic Mrp4 induction following acetaminophen exposure is dependent on Kupffer cell function

(2008) Sarah N. Campion et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Hepatocellular transport in acquired cholestasis: new insights into functional, regulatory and therapeutic aspects

(2008) Marcelo G. Roma et al.   CLINICAL SCIENCE

Regulation of Drug Transporter Expression in Human Hepatocytes Exposed to the Proinflammatory Cytokines Tumor Necrosis Factor-  or Interleukin-6

(2008) M. L. Vee et al.   DRUG METABOLISM AND DISPOSITION

Identification and Characterization of a Major Liver Lysophosphatidylcholine Acyltransferase

(2008) Yang Zhao et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Identification of a Novel Noninflammatory Biosynthetic Pathway of Platelet-activating Factor

(2008) Takeshi Harayama et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Thematic Review Series: Glycerolipids.Phosphatidylcholine and choline homeostasis

(2008) Zhaoyu Li et al.   JOURNAL OF LIPID RESEARCH