MALDI Imaging mass spectrometry: current frontiers and perspectives in pathology research and practice

Novel Approach of MALDI Drug Imaging, Immunohistochemistry, and Digital Image Analysis for Drug Distribution Studies in Tissues

(2014) Katharina Huber et al.   ANALYTICAL CHEMISTRY

De novodiscovery of phenotypic intratumour heterogeneity using imaging mass spectrometry

(2014) Benjamin Balluff et al.   JOURNAL OF PATHOLOGY

High-resolution metabolite imaging of light and dark treated retina using MALDI-FTICR mass spectrometry

(2014) Na Sun et al.   PROTEOMICS

Imaging mass spectrometry to discriminate breast from pancreatic cancer metastasis in formalin-fixed paraffin-embedded tissues

(2014) Rita Casadonte et al.   PROTEOMICS

MALDI imaging–based identification of prognostically relevant signals in bladder cancer using large-scale tissue microarrays1These authors contributed equally to this work.

(2014) Stefan Steurer et al.   UROLOGIC ONCOLOGY-SEMINARS AND ORIGINAL INVESTIGATIONS

Qualitative and quantitative mass spectrometry imaging of drugs and metabolites

(2013) Christopher B. Lietz et al.   ADVANCED DRUG DELIVERY REVIEWS

Comprehensive Imaging of Porcine Adrenal Gland Lipids by MALDI-FTMS Using Quercetin as a Matrix

(2013) Xiaodong Wang et al.   ANALYTICAL CHEMISTRY

Accumulated phosphatidylcholine (16:0/16:1) in human colorectal cancer; possible involvement of LPCAT4

(2013) Nobuya Kurabe et al.   CANCER SCIENCE

Analysis of Tissue Specimens by Matrix-Assisted Laser Desorption/Ionization Imaging Mass Spectrometry in Biological and Clinical Research

(2013) Jeremy L. Norris et al.   CHEMICAL REVIEWS

Imaging mass spectrometry reveals modified forms of histone H4 as new biomarkers of microvascular invasion in hepatocellular carcinomas

(2013) Nicolas Poté et al.   HEPATOLOGY

Mass spectrometry imaging with high resolution in mass and space

(2013) Andreas Römpp et al.   HISTOCHEMISTRY AND CELL BIOLOGY

Qualitative and quantitative mass spectrometry imaging of drugs and metabolites in tissue at therapeutic levels

(2013) Na Sun et al.   HISTOCHEMISTRY AND CELL BIOLOGY

MALDI mass spectrometric imaging based identification of clinically relevant signals in prostate cancer using large-scale tissue microarrays

(2013) Stefan Steurer et al.   INTERNATIONAL JOURNAL OF CANCER

Clinical response to chemotherapy in oesophageal adenocarcinoma patients is linked to defects in mitochondria

(2013) Michaela Aichler et al.   JOURNAL OF PATHOLOGY

MSiMass List: A Public Database of Identifications for Protein MALDI MS Imaging

(2013) Liam A. McDonnell et al.   JOURNAL OF PROTEOME RESEARCH

Comprehensive Identification of Proteins from MALDI Imaging

(2013) Stefan K. Maier et al.   MOLECULAR & CELLULAR PROTEOMICS

Energy Management by Enhanced Glycolysis in G1-phase in Human Colon Cancer Cells In Vitro and In Vivo

(2013) Y. Bao et al.   MOLECULAR CANCER RESEARCH

Determination of Paclitaxel Distribution in Solid Tumors by Nano-Particle Assisted Laser Desorption Ionization Mass Spectrometry Imaging

(2013) Lavinia Morosi et al.   PLoS One

Imaging mass spectrometry: A new tool for pathology in a molecular age

(2013) Jeremy L. Norris et al.   Proteomics Clinical Applications

Quantitative MALDI Tandem Mass Spectrometric Imaging of Cocaine from Brain Tissue with a Deuterated Internal Standard

(2012) David A. Pirman et al.   ANALYTICAL CHEMISTRY

Sublimation of New Matrix Candidates for High Spatial Resolution Imaging Mass Spectrometry of Lipids: Enhanced Information in Both Positive and Negative Polarities after 1,5-Diaminonapthalene Deposition

(2012) Aurélien Thomas et al.   ANALYTICAL CHEMISTRY

Mapping of phospholipids by MALDI imaging (MALDI-MSI): realities and expectations

(2012) Louis J. Sparvero et al.   CHEMISTRY AND PHYSICS OF LIPIDS

Lipid metabolism in cancer

(2012) Claudio R. Santos et al.   FEBS Journal

Tumor Classification of Six Common Cancer Types Based on Proteomic Profiling by MALDI Imaging

(2012) Stephan Meding et al.   JOURNAL OF PROTEOME RESEARCH

Mass spectrometry imaging for drug distribution studies

(2012) Brendan Prideaux et al.   Journal of Proteomics

Cancer of unknown primary site

(2012) Nicholas Pavlidis et al.   LANCET

Genetic heterogeneity and cancer drug resistance

(2012) Nicholas C Turner et al.   LANCET ONCOLOGY

Detection of high molecular weight proteins by MALDI imaging mass spectrometry

(2012) Veronica Mainini et al.   Molecular BioSystems

Clonal evolution in cancer

(2012) Mel Greaves et al.   NATURE

Intratumor Heterogeneity and Branched Evolution Revealed by Multiregion Sequencing

(2012) Marco Gerlinger et al.   NEW ENGLAND JOURNAL OF MEDICINE

Imaging Mass Spectrometry—A New and Promising Method to Differentiate Spitz Nevi From Spitzoid Malignant Melanomas

(2011) Rossitza Lazova et al.   AMERICAN JOURNAL OF DERMATOPATHOLOGY

MALDI Imaging Identifies Prognostic Seven-Protein Signature of Novel Tissue Markers in Intestinal-Type Gastric Cancer

(2011) Benjamin Balluff et al.   AMERICAN JOURNAL OF PATHOLOGY

Mass spectrometry imaging with high resolution in mass and space (HR2 MSI) for reliable investigation of drug compound distributions on the cellular level

(2011) Andreas Römpp et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

Performance and Cost Analysis of Matrix-Assisted Laser Desorption Ionization-Time of Flight Mass Spectrometry for Routine Identification of Yeast

(2011) N. Dhiman et al.   JOURNAL OF CLINICAL MICROBIOLOGY

Mass spectrometry imaging for drugs and metabolites

(2011) Tyler Greer et al.   Journal of Proteomics

Drug localization in different lung cancer phenotypes by MALDI mass spectrometry imaging

(2011) György Marko-Varga et al.   Journal of Proteomics

Compelling Evidence for Lucky Survivor and Gas Phase Protonation: The Unified MALDI Analyte Protonation Mechanism

(2011) Thorsten W. Jaskolla et al.   JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY

Investigative pathology: leading the post-genomic revolution

(2011) David M Berman et al.   LABORATORY INVESTIGATION

Single-cell dissection of transcriptional heterogeneity in human colon tumors

(2011) Piero Dalerba et al.   NATURE BIOTECHNOLOGY

Multiple Statistical Analysis Techniques Corroborate Intratumor Heterogeneity in Imaging Mass Spectrometry Datasets of Myxofibrosarcoma

(2011) Emrys A. Jones et al.   PLoS One

MALDI imaging mass spectrometry: bridging biology and chemistry in drug development

(2011) Stephen Castellino et al.   Bioanalysis

Novel molecular tumour classification using MALDI–mass spectrometry imaging of tissue micro-array

(2010) Marie-Claude Djidja et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

High-Spatial Resolution Matrix-Assisted Laser Desorption Ionization Imaging Analysis of Glucosylceramide in Spleen Sections from a Mouse Model of Gaucher Disease

(2010) Marten F. Snel et al.   ANALYTICAL CHEMISTRY

Ultrahighly Sensitive in Situ Metabolomic Imaging for Visualizing Spatiotemporal Metabolic Behaviors

(2010) Daisuke Miura et al.   ANALYTICAL CHEMISTRY

Histology by Mass Spectrometry: Label-Free Tissue Characterization Obtained from High-Accuracy Bioanalytical Imaging

(2010) Andreas Römpp et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Paradoxical ATP Elevation in Ischemic Penumbra Revealed by Quantitative Imaging Mass Spectrometry

(2010) Katsuji Hattori et al.   ANTIOXIDANTS & REDOX SIGNALING

Identification of Markers of Taxane Sensitivity Using Proteomic and Genomic Analyses of Breast Tumors from Patients Receiving Neoadjuvant Paclitaxel and Radiation

(2010) J. A. Bauer et al.   CLINICAL CANCER RESEARCH

Matrix-assisted laser-desorption/ionization BIOTYPER: experience in the routine of a University hospital

(2010) E. Bessède et al.   CLINICAL MICROBIOLOGY AND INFECTION

Localization and imaging of sialylated glycosphingolipids in brain tissue sections by MALDI mass spectrometry

(2010) B. Colsch et al.   GLYCOBIOLOGY

Longitudinal changes of adiponectin, carbohydrate and lipid metabolism in pregnant women at high risk for gestational diabetes

(2010) Giancarlo Paradisi et al.   GYNECOLOGICAL ENDOCRINOLOGY

Intratumoral heterogeneity of HER-2 gene amplification and protein overexpression in breast cancer

(2010) Julie M. Wu et al.   HUMAN PATHOLOGY

Proteomic profiling of mucosal and submucosal colonic tissues yields protein signatures that differentiate the inflammatory colitides

(2010) Amosy E. MʼKoma et al.   INFLAMMATORY BOWEL DISEASES

Application of MALDI imaging for the diagnosis of classical Hodgkin lymphoma

(2010) Kristina Schwamborn et al.   JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY

Visualizing spatial lipid distribution in porcine lens by MALDI imaging high-resolution mass spectrometry

(2010) Veronika Vidová et al.   JOURNAL OF LIPID RESEARCH

Mass-spectrometry based oxidative lipidomics and lipid imaging: applications in traumatic brain injury

(2010) Louis J. Sparvero et al.   JOURNAL OF NEUROCHEMISTRY

Imaging mass spectrometry of myxoid sarcomas identifies proteins and lipids specific to tumour type and grade, and reveals biochemical intratumour heterogeneity

(2010) Stefan M Willems et al.   JOURNAL OF PATHOLOGY

Classification of HER2/neu Status in Gastric Cancer Using a Breast-Cancer Derived Proteome Classifier

(2010) Benjamin Balluff et al.   JOURNAL OF PROTEOME RESEARCH

Classification of HER2 Receptor Status in Breast Cancer Tissues by MALDI Imaging Mass Spectrometry

(2010) Sandra Rauser et al.   JOURNAL OF PROTEOME RESEARCH

Liquid ionic matrixes for MALDI mass spectrometry imaging of lipids

(2010) Céline Meriaux et al.   Journal of Proteomics

Fine Mapping the Spatial Distribution and Concentration of Unlabeled Drugs within Tissue Micro-Compartments Using Imaging Mass Spectrometry

(2010) Anna Nilsson et al.   PLoS One

Mass spectrometry imaging of rat brain sections: nanomolar sensitivity with MALDI versus nanometer resolution by TOF–SIMS

(2009) Farida Benabdellah et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

Improving Tissue Preparation for Matrix-Assisted Laser Desorption Ionization Mass Spectrometry Imaging. Part 1: Using Microspotting

(2009) Julien Franck et al.   ANALYTICAL CHEMISTRY

Imaging of Lipids in Spinal Cord Using Intermediate Pressure Matrix-Assisted Laser Desorption-Linear Ion Trap/Orbitrap MS

(2009) Rachelle R. Landgraf et al.   ANALYTICAL CHEMISTRY

Imaging mass spectrometry of gastric carcinoma in formalin-fixed paraffin-embedded tissue microarray

(2009) Yoshifumi Morita et al.   CANCER SCIENCE

Spatial and temporal alterations of phospholipids determined by mass spectrometry during mouse embryo implantation

(2009) Kristin E. Burnum et al.   JOURNAL OF LIPID RESEARCH

Visualization of the cell-selective distribution of PUFA-containing phosphatidylcholines in mouse brain by imaging mass spectrometry

(2009) Yuki Sugiura et al.   JOURNAL OF LIPID RESEARCH

Imaging Mass Spectrometry for Visualization of Drug and Endogenous Metabolite Distribution: Toward In Situ Pharmacometabolomes

(2009) Yuki Sugiura et al.   Journal of Neuroimmune Pharmacology

Organ-Specific Distributions of Lysophosphatidylcholine and Triacylglycerol in Mouse Embryo

(2009) Takahiro Hayasaka et al.   LIPIDS

MALDI reveals membrane lipid profile reversion in MDX mice

(2009) Farida Benabdellah et al.   NEUROBIOLOGY OF DISEASE

Profiling and Imaging of Lipids on Brain and Liver Tissue by Matrix-Assisted Laser Desorption/Ionization Mass Spectrometry Using 2-Mercaptobenzothiazole as a Matrix

(2008) Egoitz Astigarraga et al.   ANALYTICAL CHEMISTRY

Protein fragment imaging using ink jet printing digestion technique

(2008) Manabu Komatsu et al.   APPLIED SURFACE SCIENCE

Imaging of lipid species by MALDI mass spectrometry

(2008) Robert C. Murphy et al.   JOURNAL OF LIPID RESEARCH

Imaging Mass Spectrometry of Intact Proteins from Alcohol-Preserved Tissue Specimens: Bypassing Formalin Fixation

(2008) Pierre Chaurand et al.   JOURNAL OF PROTEOME RESEARCH

Imaging of phosphatidylcholines in the adult rat brain using MALDI-TOF MS

(2008) Sumiko Mikawa et al.   NEUROSCIENCE LETTERS

High-throughput proteomic analysis of formalin-fixed paraffin-embedded tissue microarrays using MALDI imaging mass spectrometry

(2008) M. Reid Groseclose et al.   PROTEOMICS