MALDI imaging mass spectrometry: bridging biology and chemistry in drug development

Molecular imaging and depth profiling by mass spectrometry—SIMS, MALDI or DESI?

(2011) John C. Vickerman   ANALYST

Mass spectrometry imaging with high resolution in mass and space (HR2 MSI) for reliable investigation of drug compound distributions on the cellular level

(2011) Andreas Römpp et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

Normalization in MALDI-TOF imaging datasets of proteins: practical considerations

(2011) Sören-Oliver Deininger et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

Poly[N-(2-hydroxypropyl)methacrylamide]-Based Tissue-Embedding Medium Compatible with MALDI Mass Spectrometry Imaging Experiments

(2011) Martin Strohalm et al.   ANALYTICAL CHEMISTRY

High-Sensitivity MALDI-MRM-MS Imaging of Moxifloxacin Distribution in Tuberculosis-Infected Rabbit Lungs and Granulomatous Lesions

(2011) Brendan Prideaux et al.   ANALYTICAL CHEMISTRY

Drug and metabolite concentrations in tissues in relationship to tissue adverse findings: a review

(2011) Mario Pellegatti et al.   Expert Opinion on Drug Metabolism & Toxicology

Drug localization in different lung cancer phenotypes by MALDI mass spectrometry imaging

(2011) György Marko-Varga et al.   Journal of Proteomics

Compelling Evidence for Lucky Survivor and Gas Phase Protonation: The Unified MALDI Analyte Protonation Mechanism

(2011) Thorsten W. Jaskolla et al.   JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY

Distribution of chloroquine in ocular tissue of pigmented rat using matrix-assisted laser desorption/ionization imaging quadrupole time-of-flight tandem mass spectrometry

(2011) Yasuhiro Yamada et al.   RAPID COMMUNICATIONS IN MASS SPECTROMETRY

A quantitation method for mass spectrometry imaging

(2011) Stormy L. Koeniger et al.   RAPID COMMUNICATIONS IN MASS SPECTROMETRY

MALDI imaging mass spectrometry of human tissue: method challenges and clinical perspectives

(2011) Erin H. Seeley et al.   TRENDS IN BIOTECHNOLOGY

MALDI imaging techniques dedicated to drug-distribution studies

(2011) David Bonnel et al.   Bioanalysis

Mass Spectrometry–Based Biomarker Discovery: Toward a Global Proteome Index of Individuality

(2010) Adam M. Hawkridge et al.   Annual Review of Analytical Chemistry

Molecular mass spectrometry imaging in biomedical and life science research

(2010) Jaroslav Pól et al.   HISTOCHEMISTRY AND CELL BIOLOGY

A concise review of mass spectrometry imaging

(2010) Erika R. Amstalden van Hove et al.   JOURNAL OF CHROMATOGRAPHY A

From Whole-body Sections Down to Cellular Level, Multiscale Imaging of Phospholipids by MALDI Mass Spectrometry

(2010) Pierre Chaurand et al.   MOLECULAR & CELLULAR PROTEOMICS

MALDI Imaging Mass Spectrometry - Painting Molecular Pictures

(2010) Kristina Schwamborn et al.   Molecular Oncology

Comparison of Normalization Methods for the Identification of Biomarkers Using MALDI-TOF and SELDI-TOF Mass Spectra

(2010) Sanket P. Borgaonkar et al.   OMICS-A JOURNAL OF INTEGRATIVE BIOLOGY

Mass spectrometric imaging of small molecules

(2010) Aleš Svatoš   TRENDS IN BIOTECHNOLOGY

Mass spectrometry imaging of pharmacological compounds in tissue sections

(2010) Richard JA Goodwin et al.   Bioanalysis

Autoradiography, MALDI-MS, and SIMS-MS Imaging in Pharmaceutical Discovery and Development

(2009) Eric G. Solon et al.   AAPS Journal

Mass defect filter technique and its applications to drug metabolite identification by high-resolution mass spectrometry

(2009) Haiying Zhang et al.   JOURNAL OF MASS SPECTROMETRY

Imaging Mass Spectrometry for Visualization of Drug and Endogenous Metabolite Distribution: Toward In Situ Pharmacometabolomes

(2009) Yuki Sugiura et al.   Journal of Neuroimmune Pharmacology

Imaging mass spectrometry: Hype or hope?

(2009) Ron M. A. Heeren et al.   JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY

Matrix-assisted laser desorption/ionization mass spectrometric imaging of complete rat sections using a triple quadrupole linear ion trap

(2009) Gérard Hopfgartner et al.   RAPID COMMUNICATIONS IN MASS SPECTROMETRY

Comparison of normalisation methods for surface-enhanced laser desorption and ionisation (SELDI) time-of-flight (TOF) mass spectrometry data

(2008) Wouter Meuleman et al.   BMC BIOINFORMATICS

Ion mobility-mass spectrometry

(2008) Abu B. Kanu et al.   JOURNAL OF MASS SPECTROMETRY

Orbitrap mass spectrometry: Instrumentation, ion motion and applications

(2008) Richard H. Perry et al.   MASS SPECTROMETRY REVIEWS

High-throughput proteomic analysis of formalin-fixed paraffin-embedded tissue microarrays using MALDI imaging mass spectrometry

(2008) M. Reid Groseclose et al.   PROTEOMICS

Mass defect profiles of biological matrices and the general applicability of mass defect filtering for metabolite detection

(2008) Haiying Zhang et al.   RAPID COMMUNICATIONS IN MASS SPECTROMETRY