标题
Leading compounds for the validation of animal models of psychopathology
作者
关键词
Depression, Schizophrenia, Animal models, Antipsychotics, Antidepressants
出版物
CELL AND TISSUE RESEARCH
Volume 354, Issue 1, Pages 309-330
出版商
Springer Nature
发表日期
2013-08-14
DOI
10.1007/s00441-013-1692-9
参考文献
相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。- Protective effects of histamine H3-receptor ligands in schizophrenic behaviors in experimental models
- (2014) Mahmood Danish et al. Pharmacological Reports
- Effects of risperidone, clozapine and the 5-HT6 antagonist GSK-742457 on PCP-induced deficits in reversal learning in the two-lever operant task in male Sprague Dawley rats
- (2013) N.M.W.J. de Bruin et al. BEHAVIOURAL BRAIN RESEARCH
- Sustained Impairment of α2A-Adrenergic Autoreceptor Signaling Mediates Neurochemical and Behavioral Sensitization to Amphetamine
- (2013) Emilie L. Doucet et al. BIOLOGICAL PSYCHIATRY
- Behavioural alterations relevant to developmental brain disorders in mice with neonatally induced ventral hippocampal lesions
- (2013) Arne Naert et al. BRAIN RESEARCH BULLETIN
- Pharmacological Properties of Glutamatergic Drugs Targeting NMDA Receptors and their Application in Major Depression
- (2013) Gianluca Serafini et al. CURRENT PHARMACEUTICAL DESIGN
- Glutamate modulators as potential therapeutic drugs in schizophrenia and affective disorders
- (2013) Kenji Hashimoto et al. EUROPEAN ARCHIVES OF PSYCHIATRY AND CLINICAL NEUROSCIENCE
- Stimulation of Metabotropic Glutamate (mGlu) 2 Receptor and Blockade of mGlu1 Receptor Improve Social Memory Impairment Elicited by MK-801 in Rats
- (2013) Hirohiko Hikichi et al. JOURNAL OF PHARMACOLOGICAL SCIENCES
- The 5-hydroxytryptamine (serotonin) receptor 6 agonist EMD 386088 ameliorates ketamine-induced deficits in attentional set shifting and novel object recognition, but not in the prepulse inhibition in rats
- (2013) Agnieszka Nikiforuk et al. JOURNAL OF PSYCHOPHARMACOLOGY
- Repeated potentiation of the metabotropic glutamate receptor 5 and the alpha 7 nicotinic acetylcholine receptor modulates behavioural and GABAergic deficits induced by early postnatal phencyclidine (PCP) treatment
- (2013) Celia Kjaerby et al. NEUROPHARMACOLOGY
- Long-lasting changes in hippocampal synaptic plasticity and cognition in an animal model of NMDA receptor dysfunction in psychosis
- (2013) Valentina Wiescholleck et al. NEUROPHARMACOLOGY
- GLYX-13, a NMDA Receptor Glycine-Site Functional Partial Agonist, Induces Antidepressant-Like Effects Without Ketamine-Like Side Effects
- (2013) Jeffrey Burgdorf et al. NEUROPSYCHOPHARMACOLOGY
- Abnormal Stress Responsivity in a Rodent Developmental Disruption Model of Schizophrenia
- (2013) Eric C Zimmerman et al. NEUROPSYCHOPHARMACOLOGY
- Biological rhythms and melatonin in mood disorders and their treatments
- (2013) Laurence Lanfumey et al. PHARMACOLOGY & THERAPEUTICS
- Etazolate, a phosphodiesterase 4 inhibitor reverses chronic unpredictable mild stress-induced depression-like behavior and brain oxidative damage
- (2013) Ankur Jindal et al. PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR
- Effects of ketamine and LY341495 on the depressive-like behavior of repeated corticosterone-injected rats
- (2013) Hiroyuki Koike et al. PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR
- The neurobiology of depression--revisiting the serotonin hypothesis. II. Genetic, epigenetic and clinical studies
- (2013) P. R. Albert et al. PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES
- Neonatal Disruption of Serine Racemase Causes Schizophrenia-Like Behavioral Abnormalities in Adulthood: Clinical Rescue by D-Serine
- (2013) Hiroko Hagiwara et al. PLoS One
- The antipsychotic-like effects of the mGlu group III orthosteric agonist, LSP1-2111, involves 5-HT1A signalling
- (2013) Joanna M. Wierońska et al. PSYCHOPHARMACOLOGY
- Increasing the validity of experimental models for depression
- (2012) Kafui Dzirasa et al. Annals of the New York Academy of Sciences
- The effects of isolated and enriched housing conditions on baseline and drug-induced behavioural responses in the male rat
- (2012) Joy Simpson et al. BEHAVIOURAL BRAIN RESEARCH
- Prefrontal dopamine release and sensory-specific satiety altered in rats with neonatal ventral hippocampal lesions
- (2012) Carlos Eduardo Macedo et al. BEHAVIOURAL BRAIN RESEARCH
- Deep brain stimulation of the entopeduncular nucleus in rats prevents apomorphine-induced deficient sensorimotor gating
- (2012) Dominic K. Posch et al. BEHAVIOURAL BRAIN RESEARCH
- Tianeptine treatment induces antidepressive-like effects and alters BDNF and energy metabolism in the brain of rats
- (2012) Franciela P. Della et al. BEHAVIOURAL BRAIN RESEARCH
- Fluoxetine modulates hippocampal cell signaling pathways implicated in neuroplasticity in olfactory bulbectomized mice
- (2012) Andiara E. Freitas et al. BEHAVIOURAL BRAIN RESEARCH
- Antidepressant Effects of the Muscarinic Cholinergic Receptor Antagonist Scopolamine: A Review
- (2012) Wayne C. Drevets et al. BIOLOGICAL PSYCHIATRY
- Social isolation rearing induces mitochondrial, immunological, neurochemical and behavioural deficits in rats, and is reversed by clozapine or N-acetyl cysteine
- (2012) Marisa Möller et al. BRAIN BEHAVIOR AND IMMUNITY
- Post-weaning social isolation rearing influences the expression of molecules related to inhibitory neurotransmission and structural plasticity in the amygdala of adult rats
- (2012) Javier Gilabert-Juan et al. BRAIN RESEARCH
- Chronic blockade of CB1receptors reverses startle gating deficits and associated neurochemical alterations in rats reared in isolation
- (2012) E Zamberletti et al. BRITISH JOURNAL OF PHARMACOLOGY
- Blockade of the high-affinity noradrenaline transporter (NET) by the selective 5-HT reuptake inhibitor escitalopram: anin vivomicrodialysis study in mice
- (2012) Hai T Nguyen et al. BRITISH JOURNAL OF PHARMACOLOGY
- Sensory and Sensorimotor Gating Deficits after Neonatal Ventral Hippocampal Lesions in Rats
- (2012) Neal R. Swerdlow et al. DEVELOPMENTAL NEUROSCIENCE
- Targeting the Glutamatergic System to Treat Major Depressive Disorder
- (2012) Daniel C. Mathews et al. DRUGS
- A novel glycine transporter-1 (GlyT1) inhibitor, ASP2535 (4-[3-isopropyl-5-(6-phenyl-3-pyridyl)-4H-1,2,4-triazol-4-yl]-2,1,3-benzoxadiazole), improves cognition in animal models of cognitive impairment in schizophrenia and Alzheimer's disease
- (2012) Katsuya Harada et al. EUROPEAN JOURNAL OF PHARMACOLOGY
- Synergistic antidepressant-like action of gaboxadol and escitalopram
- (2012) Trine Christensen et al. EUROPEAN NEUROPSYCHOPHARMACOLOGY
- Emerging drugs for major depressive disorder
- (2012) Kevin Ryan Connolly et al. EXPERT OPINION ON EMERGING DRUGS
- Phosphodiesterase 10A inhibitors: a 2009 – 2012 patent update
- (2012) Jan Kehler EXPERT OPINION ON THERAPEUTIC PATENTS
- Preclinical evaluation of non-imidazole histamine H3 receptor antagonists in comparison to atypical antipsychotics for the treatment of cognitive deficits associated with schizophrenia
- (2012) Jordan W. Brown et al. INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY
- Disruption of prefrontal cortical–hippocampal balance in a developmental model of schizophrenia: reversal by sulpiride
- (2012) Pauline Belujon et al. INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY
- Active behaviours produced by antidepressants and opioids in the mouse tail suspension test
- (2012) Esther Berrocoso et al. INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY
- Behavioural and neurochemical changes induced by stress-related conditions are counteracted by the neurokinin-2 receptor antagonist saredutant
- (2012) Alessandra Tamburella et al. INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY
- Cortisol responses to psychosocial stress predict depression trajectories: Social-evaluative threat and prior depressive episodes as moderators
- (2012) Matthew C. Morris et al. JOURNAL OF AFFECTIVE DISORDERS
- Prenatal Immune Activation Interacts with Genetic Nurr1 Deficiency in the Development of Attentional Impairments
- (2012) S. Vuillermot et al. JOURNAL OF NEUROSCIENCE
- T-817MA, a novel neurotrophic agent, ameliorates loss of GABAergic parvalbumin-positive neurons and sensorimotor gating deficits in rats transiently exposed to MK-801 in the neonatal period
- (2012) Takashi Uehara et al. JOURNAL OF PSYCHIATRIC RESEARCH
- Cannabidiol and clozapine reverse MK-801-induced deficits in social interaction and hyperactivity in Sprague–Dawley rats
- (2012) Anand Gururajan et al. JOURNAL OF PSYCHOPHARMACOLOGY
- Effects of fluoxetine, tianeptine and olanzapine on unpredictable chronic mild stress-induced depression-like behavior in mice
- (2012) Oguz Mutlu et al. LIFE SCIENCES
- Using the rat forced swim test to assess antidepressant-like activity in rodents
- (2012) David A Slattery et al. Nature Protocols
- Neuropeptide receptor ligands as drugs for psychiatric diseases: the end of the beginning?
- (2012) Guy Griebel et al. NATURE REVIEWS DRUG DISCOVERY
- Early Cognitive Experience Prevents Adult Deficits in a Neurodevelopmental Schizophrenia Model
- (2012) Heekyung Lee et al. NEURON
- In vitro characterisation of the novel positive allosteric modulators of the mGlu5 receptor, LSN2463359 and LSN2814617, and their effects on sleep architecture and operant responding in the rat
- (2012) Gary Gilmour et al. NEUROPHARMACOLOGY
- Antidepressant-like properties of three new α2-adrenoceptor antagonists
- (2012) Carolina Muguruza et al. NEUROPHARMACOLOGY
- The novel phosphodiesterase 10A inhibitor THPP-1 has antipsychotic-like effects in rat and improves cognition in rat and rhesus monkey
- (2012) Sean M. Smith et al. NEUROPHARMACOLOGY
- The mGlu5 positive allosteric modulator LSN2463359 differentially modulates motor, instrumental and cognitive effects of NMDA receptor antagonists in the rat
- (2012) Francois Gastambide et al. NEUROPHARMACOLOGY
- mGlu2/3 and mGlu5 receptors: Potential targets for novel antidepressants
- (2012) Shigeyuki Chaki et al. NEUROPHARMACOLOGY
- Negative allosteric modulation of metabotropic glutamate receptor 5 results in broad spectrum activity relevant to treatment resistant depression
- (2012) Z.A. Hughes et al. NEUROPHARMACOLOGY
- Gestational Methylazoxymethanol Exposure Leads to NMDAR Dysfunction in Hippocampus During Early Development and Lasting Deficits in Learning
- (2012) Melissa A Snyder et al. NEUROPSYCHOPHARMACOLOGY
- Acute N-methyl-d-aspartate receptor hypofunction induced by MK801 evokes sex-specific changes in behaviors observed in open-field testing in adult male and proestrus female rats
- (2012) I. Feinstein et al. NEUROSCIENCE
- Endocannabinoid system and mood disorders: Priming a target for new therapies
- (2012) Vincenzo Micale et al. PHARMACOLOGY & THERAPEUTICS
- Nitric oxide modulates apomorphine-induced recognition memory deficits in rats
- (2012) Ioannis Gourgiotis et al. PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR
- Fluoxetine reverses depressive-like behaviors and increases hippocampal acetylcholinesterase activity induced by olfactory bulbectomy
- (2012) Daniele G. Machado et al. PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR
- Differential effects of antipsychotics on hippocampal presynaptic protein expressions and recognition memory in a schizophrenia model in mice
- (2012) H. Ozdemir et al. PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY
- Prolactin concentrations during aripiprazole treatment in relation to sex, plasma drugs concentrations and genetic polymorphisms ofdopamine D2 receptorandcytochrome P450 2D6in Japanese patients with schizophrenia
- (2012) Goyo Nagai et al. PSYCHIATRY AND CLINICAL NEUROSCIENCES
- Enhancement of social novelty discrimination by positive allosteric modulators at metabotropic glutamate 5 receptors: adolescent administration prevents adult-onset deficits induced by neonatal treatment with phencyclidine
- (2012) Nicholas E. Clifton et al. PSYCHOPHARMACOLOGY
- Persistent effects of chronic clozapine on the cellular and behavioral responses to LSD in mice
- (2012) José L. Moreno et al. PSYCHOPHARMACOLOGY
- A dysphoric-like state during early withdrawal from extended access to methamphetamine self-administration in rats
- (2012) Choon-Gon Jang et al. PSYCHOPHARMACOLOGY
- Twenty-five Years of Glutamate in Schizophrenia: Are We There Yet?
- (2012) D. C. Javitt SCHIZOPHRENIA BULLETIN
- Effects of omega-3 dietary supplement in prevention of positive, negative and cognitive symptoms: A study in adolescent rats with ketamine-induced model of schizophrenia
- (2012) Clarissa S. Gama et al. SCHIZOPHRENIA RESEARCH
- Increased antidepressant-like effect of desipramine combined with central stimulants (caffeine and amphetamine) in mice
- (2012) Evelyn Robles-Molina et al. Open Life Sciences
- Endocannabinoid system dysfunction in mood and related disorders
- (2011) C. H. Ashton et al. ACTA PSYCHIATRICA SCANDINAVICA
- Synaptic transmission changes in fear memory circuits underlie key features of an animal model of schizophrenia
- (2011) Marie Pollard et al. BEHAVIOURAL BRAIN RESEARCH
- Targeting the nicotinic alpha7 acetylcholine receptor to enhance cognition in disease
- (2011) Tanya L. Wallace et al. BIOCHEMICAL PHARMACOLOGY
- Progressive Brain Change in Schizophrenia: A Prospective Longitudinal Study of First-Episode Schizophrenia
- (2011) Nancy C. Andreasen et al. BIOLOGICAL PSYCHIATRY
- Effects of risperidone treatment in adolescence on hippocampal neurogenesis, parvalbumin expression, and vascularization following prenatal immune activation in rats
- (2011) Yael Piontkewitz et al. BRAIN BEHAVIOR AND IMMUNITY
- Animal models of schizophrenia
- (2011) CA Jones et al. BRITISH JOURNAL OF PHARMACOLOGY
- Ciproxifan, a histamine H3-receptor antagonist / inverse agonist, modulates methamphetamine-induced sensitization in mice
- (2011) Mouhammad Motawaj et al. EUROPEAN JOURNAL OF NEUROSCIENCE
- Antipsychotic effects of N-desmethylclozapine on sensorimotor gating function in rats — Possible involvement of activation of M1 muscarinic receptors
- (2011) Shunsuke Maehara et al. EUROPEAN JOURNAL OF PHARMACOLOGY
- Pramipexole is active in depression tests and modulates monoaminergic transmission, but not brain levels of BDNF in mice
- (2011) Olaf Schulte-Herbrüggen et al. EUROPEAN JOURNAL OF PHARMACOLOGY
- Agomelatine suppresses locomotor hyperactivity in olfactory bulbectomised rats: A comparison to melatonin and to the 5-HT2c antagonist, S32006
- (2011) Trevor R. Norman et al. EUROPEAN JOURNAL OF PHARMACOLOGY
- Translating potential biomarker candidates for schizophrenia and depression to animal models of psychiatric disorders
- (2011) Wolfgang Kluge et al. EXPERT REVIEW OF MOLECULAR DIAGNOSTICS
- Differential behavioural and neurochemical outcomes from chronic paroxetine treatment in adolescent and adult rats: a model of adverse antidepressant effects in human adolescents?
- (2011) Emily Karanges et al. INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY
- The M1/M4 preferring agonist xanomeline reverses amphetamine-, MK801- and scopolamine-induced abnormalities of latent inhibition: putative efficacy against positive, negative and cognitive symptoms in schizophrenia
- (2011) Segev Barak et al. INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY
- Importance of inter-hemispheric prefrontal connection in the effects of non-competitive NMDA receptor antagonists
- (2011) Xavier López-Gil et al. INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY
- The effects of methamphetamine self-administration on behavioural sensitization in the olfactory bulbectomy rat model of depression
- (2011) Jana Kucerova et al. INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY
- Mouse strain differences in phencyclidine-induced behavioural changes
- (2011) Akihiro Mouri et al. INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY
- Characterization of an mGluR2/3 Negative Allosteric Modulator in Rodent Models of Depression
- (2011) Brice Campo et al. JOURNAL OF NEUROGENETICS
- Antipsychotic Drugs Rapidly Induce Dopamine Neuron Depolarization Block in a Developmental Rat Model of Schizophrenia
- (2011) O. Valenti et al. JOURNAL OF NEUROSCIENCE
- The endocannabinoid system in the regulation of emotions throughout lifespan: a discussion on therapeutic perspectives
- (2011) Eva M Marco et al. JOURNAL OF PSYCHOPHARMACOLOGY
- Involvement of the mammalian target of rapamycin signaling in the antidepressant-like effect of group II metabotropic glutamate receptor antagonists
- (2011) Hiroyuki Koike et al. NEUROPHARMACOLOGY
- An animal model of schizophrenia based on chronic LSD administration: Old idea, new results
- (2011) Danuta Marona-Lewicka et al. NEUROPHARMACOLOGY
- Influence of social isolation in the rat on serotonergic function and memory – Relevance to models of schizophrenia and the role of 5-HT6 receptors
- (2011) Charles A. Marsden et al. NEUROPHARMACOLOGY
- The antidepressant-like effects of glutamatergic drugs ketamine and AMPA receptor potentiator LY 451646 are preserved in bdnf+/− heterozygous null mice
- (2011) Jesse S.O. Lindholm et al. NEUROPHARMACOLOGY
- Clozapine administration reverses behavioral, neuronal, and nitric oxide disturbances in the neonatal ventral hippocampus rat
- (2011) Maria Elena Bringas et al. NEUROPHARMACOLOGY
- A stereological comparison of GAD67 and reelin expression in the hippocampal stratum oriens of offspring from two mouse models of maternal inflammation during pregnancy
- (2011) Louise Harvey et al. NEUROPHARMACOLOGY
- Glycine reuptake inhibitor RG1678: A pharmacologic characterization of an investigational agent for the treatment of schizophrenia
- (2011) Daniela Alberati et al. NEUROPHARMACOLOGY
- Towards a glutamate hypothesis of depression
- (2011) Gerard Sanacora et al. NEUROPHARMACOLOGY
- A Novel α5GABAAR-Positive Allosteric Modulator Reverses Hyperactivation of the Dopamine System in the MAM Model of Schizophrenia
- (2011) Kathryn M Gill et al. NEUROPSYCHOPHARMACOLOGY
- Muscarinic and Nicotinic Acetylcholine Receptor Agonists and Allosteric Modulators for the Treatment of Schizophrenia
- (2011) Carrie K Jones et al. NEUROPSYCHOPHARMACOLOGY
- Selective Remediation of Reversal Learning Deficits in the Neurodevelopmental MAM Model of Schizophrenia by a Novel mGlu5 Positive Allosteric Modulator
- (2011) Francois Gastambide et al. NEUROPSYCHOPHARMACOLOGY
- Drug withdrawal-induced depression: Serotonergic and plasticity changes in animal models
- (2011) Thibault Renoir et al. NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS
- Activation of group II metabotropic glutamate receptors induces long-term depression of excitatory synaptic transmission in the substantia nigra pars reticulata
- (2011) Kari A. Johnson et al. NEUROSCIENCE LETTERS
- Metabotropic glutamate mGlu2 receptor is necessary for the pharmacological and behavioral effects induced by hallucinogenic 5-HT2A receptor agonists
- (2011) José L. Moreno et al. NEUROSCIENCE LETTERS
- Cortical disinhibition in the neonatal ventral hippocampal lesion model of schizophrenia: New vistas on possible therapeutic approaches
- (2011) Patricio O'Donnell PHARMACOLOGY & THERAPEUTICS
- Time course of the attenuation effect of repeated antipsychotic treatment on prepulse inhibition disruption induced by repeated phencyclidine treatment
- (2011) Ming Li et al. PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR
- Putative cognitive enhancers in preclinical models related to schizophrenia: The search for an elusive target
- (2011) Segev Barak et al. PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR
- Novel glutamatergic agents for major depressive disorder and bipolar disorder
- (2011) Rodrigo Machado-Vieira et al. PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR
- The mGluR7 allosteric agonist AMN082 produces antidepressant-like effects by modulating glutamatergic signaling
- (2011) Stefania Risso Bradley et al. PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR
- Roles of glutamate signaling in preclinical and/or mechanistic models of depression
- (2011) Kenichi Tokita et al. PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR
- Reversal of scopolamine-induced disruption of prepulse inhibition by clozapine in mice
- (2011) Philipp Singer et al. PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR
- Comparisons of methamphetamine psychotic and schizophrenic symptoms: A differential item functioning analysis
- (2011) Manit Srisurapanont et al. PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY
- Group II mGluR agonist LY354740 and NAAG peptidase inhibitor effects on prepulse inhibition in PCP and d-amphetamine models of schizophrenia
- (2011) Caterina P. Profaci et al. PSYCHOPHARMACOLOGY
- The effects of PRX-07034, a novel 5-HT6 antagonist, on cognitive flexibility and working memory in rats
- (2011) Eric G. Mohler et al. PSYCHOPHARMACOLOGY
- Expression of parvalbumin and glutamic acid decarboxylase-67 after acute administration of MK-801. Implications for the NMDA hypofunction model of schizophrenia
- (2011) Tamara Romón et al. PSYCHOPHARMACOLOGY
- Opposing efficacy of group III mGlu receptor activators, LSP1-2111 and AMN082, in animal models of positive symptoms of schizophrenia
- (2011) Joanna M. Wierońska et al. PSYCHOPHARMACOLOGY
- The delta opioid receptor: an evolving target for the treatment of brain disorders
- (2011) Amynah A. Pradhan et al. TRENDS IN PHARMACOLOGICAL SCIENCES
- Reduced reelin protein synthesis in ventral hippocampus of isolation reared Wistar rats accompanies impaired avoidance conditioning
- (2010) Andrew W. Cassidy et al. BEHAVIOURAL BRAIN RESEARCH
- NNZ-2591, a novel diketopiperazine, prevented scopolamine-induced acute memory impairment in the adult rat
- (2010) Jian Guan et al. BEHAVIOURAL BRAIN RESEARCH
- The maternal immune activation (MIA) model of schizophrenia produces pre-pulse inhibition (PPI) deficits in both juvenile and adult rats but these effects are not associated with maternal weight loss
- (2010) Amy. R. Wolff et al. BEHAVIOURAL BRAIN RESEARCH
- Agomelatine reverses the decrease in hippocampal cell survival induced by chronic mild stress
- (2010) Girstautė Dagytė et al. BEHAVIOURAL BRAIN RESEARCH
- Blockade of stress-induced increase of glutamate release in the rat prefrontal/frontal cortex by agomelatine involves synergy between melatonergic and 5-HT2C receptor-dependent pathways
- (2010) Daniela Tardito et al. BMC NEUROSCIENCE
- Chronic buspirone treatment decreases 5-HT1B receptor densities and the serotonin transporter but increases the density of 5-HT2A receptors in the bulbectomized rat model of depression: an autoradiographic study
- (2010) Hiroki Sato et al. BRAIN RESEARCH
- Metabolic mapping of the effects of the antidepressant fluoxetine on the brains of congenitally helpless rats
- (2010) Jason Shumake et al. BRAIN RESEARCH
- The difference in effect of mGlu2/3 and mGlu5 receptor agonists on cognitive impairment induced by MK-801
- (2010) Karel Vales et al. EUROPEAN JOURNAL OF PHARMACOLOGY
- Aging impairs the antidepressant-like response to citalopram in male rats
- (2010) José Jaime Herrera-Pérez et al. EUROPEAN JOURNAL OF PHARMACOLOGY
- Adolescent chronic apomorphine treatment impairs latent inhibition and reduces prefrontal cortex mGluR5 receptor expression in adult rats
- (2010) Feng Shao et al. EUROPEAN JOURNAL OF PHARMACOLOGY
- Activation of type 5 metabotropic glutamate receptors attenuates deficits in cognitive flexibility induced by NMDA receptor blockade
- (2010) Mark R. Stefani et al. EUROPEAN JOURNAL OF PHARMACOLOGY
- The β3 adrenoceptor agonist, amibegron (SR58611A) counteracts stress-induced behavioral and neurochemical changes
- (2010) Alessandra Tamburella et al. EUROPEAN NEUROPSYCHOPHARMACOLOGY
- Isolation rearing-induced deficits in sensorimotor gating and social interaction in rats are related to cortico-striatal oxidative stress, and reversed by sub-chronic clozapine administration
- (2010) Marisa Möller et al. EUROPEAN NEUROPSYCHOPHARMACOLOGY
- Long-lasting recovery of psychotic-like symptoms in isolation-reared rats after chronic but not acute treatment with the cannabinoid antagonist AM251
- (2010) Erica Zamberletti et al. INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY
- Brain-specificPhgdhDeletion Reveals a Pivotal Role for l-Serine Biosynthesis in Controlling the Level of d-Serine, anN-methyl-d-aspartate Receptor Co-agonist, in Adult Brain
- (2010) Jung Hoon Yang et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Effects of a Positive Allosteric Modulator of Group II Metabotropic Glutamate Receptors, LY487379, on Cognitive Flexibility and Impulsive-Like Responding in Rats
- (2010) A. Nikiforuk et al. JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
- N-(4-((2-(trifluoromethyl)-3-hydroxy-4-(isobutyryl)phenoxy)methyl)benzyl)-1-methyl-1H-imidazole-4-carboxamide (THIIC), a Novel Metabotropic Glutamate 2 Potentiator with Potential Anxiolytic/Antidepressant Properties: In Vivo Profiling Suggests a Link between Behavioral and Central Nervous System Neurochemical Changes
- (2010) M. J. Fell et al. JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
- Attenuation of chronic mild stress-induced ‘anhedonia’ by asenapine is not associated with a ‘hedonic’ profile in intracranial self-stimulation
- (2010) Hugh M Marston et al. JOURNAL OF PSYCHOPHARMACOLOGY
- Increased binding of cortical and hippocampal group II metabotropic glutamate receptors in isolation-reared mice
- (2010) Toshiyuki Kawasaki et al. NEUROPHARMACOLOGY
- Late Prenatal Immune Activation in Mice Leads to Behavioral and Neurochemical Abnormalities Relevant to the Negative Symptoms of Schizophrenia
- (2010) Byron KY Bitanihirwe et al. NEUROPSYCHOPHARMACOLOGY
- Selective potentiation of the metabotropic glutamate receptor subtype 2 blocks phencyclidine-induced hyperlocomotion and brain activation
- (2010) E.A. Hackler et al. NEUROSCIENCE
- Animal models of cognitive dysfunction and negative symptoms of schizophrenia: Focus on NMDA receptor antagonism
- (2010) Joanna C. Neill et al. PHARMACOLOGY & THERAPEUTICS
- MK-801 produces a deficit in sucrose preference that is reversed by clozapine, d-serine, and the metabotropic glutamate 5 receptor positive allosteric modulator CDPPB: Relevance to negative symptoms associated with schizophrenia?
- (2010) Joshua D. Vardigan et al. PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR
- Post-weaning chronic social isolation produces profound behavioral dysregulation with decreases in prefrontal cortex synaptic-associated protein expression in female rats
- (2010) Gretchen Hermes et al. PHYSIOLOGY & BEHAVIOR
- Neuropathological and Reelin Deficiencies in the Hippocampal Formation of Rats Exposed to MAM; Differences and Similarities with Schizophrenia
- (2010) Julien Matricon et al. PLoS One
- Sex differences in the effects of N,N-diethyllysergamide (LSD) on behavioural activity and prepulse inhibition
- (2010) Tomáš Páleníček et al. PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY
- The role of glutamate on the action of antidepressants
- (2010) Kenji Hashimoto PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY
- Animal models of depression and anxiety: What do they tell us about human condition?
- (2010) I.D. Neumann et al. PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY
- In animal models, psychosocial stress-induced (neuro)inflammation, apoptosis and reduced neurogenesis are associated to the onset of depression
- (2010) Marta Kubera et al. PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY
- The glutamatergic compounds sarcosine and N-acetylcysteine ameliorate prepulse inhibition deficits in metabotropic glutamate 5 receptor knockout mice
- (2010) Hwei-Hsien Chen et al. PSYCHOPHARMACOLOGY
- Dissociating scopolamine-induced disrupted and persistent latent inhibition: stage-dependent effects of glycine and physostigmine
- (2010) Segev Barak et al. PSYCHOPHARMACOLOGY
- d-Serine and a glycine transporter-1 inhibitor enhance social memory in rats
- (2010) Toshiharu Shimazaki et al. PSYCHOPHARMACOLOGY
- E-6801, a 5-HT6 receptor agonist, improves recognition memory by combined modulation of cholinergic and glutamatergic neurotransmission in the rat
- (2010) Ian Kendall et al. PSYCHOPHARMACOLOGY
- Pharmacological characterization of social isolation-induced hyperactivity
- (2010) Katrine Fabricius et al. PSYCHOPHARMACOLOGY
- On the mechanism of the antidepressant-like action of group II mGlu receptor antagonist, MGS0039
- (2010) Agnieszka Pałucha-Poniewiera et al. PSYCHOPHARMACOLOGY
- Risperidone Administered During Asymptomatic Period of Adolescence Prevents the Emergence of Brain Structural Pathology and Behavioral Abnormalities in an Animal Model of Schizophrenia
- (2010) Y. Piontkewitz et al. SCHIZOPHRENIA BULLETIN
- Modeling cholinergic aspects of schizophrenia: Focus on the antimuscarinic syndrome
- (2009) Segev Barak BEHAVIOURAL BRAIN RESEARCH
- Gestational methylazoxymethanol acetate administration: A developmental disruption model of schizophrenia
- (2009) Daniel J. Lodge et al. BEHAVIOURAL BRAIN RESEARCH
- Pharmacological validation of a chronic social stress model of depression in rats: effects of reboxetine, haloperidol and diazepam
- (2009) Rafal Rygula et al. BEHAVIOURAL PHARMACOLOGY
- TC-5619: An alpha7 neuronal nicotinic receptor-selective agonist that demonstrates efficacy in animal models of the positive and negative symptoms and cognitive dysfunction of schizophrenia
- (2009) T.A. Hauser et al. BIOCHEMICAL PHARMACOLOGY
- Clozapine Administration in Adolescence Prevents Postpubertal Emergence of Brain Structural Pathology in an Animal Model of Schizophrenia
- (2009) Yael Piontkewitz et al. BIOLOGICAL PSYCHIATRY
- Phencyclidine-induced cognitive deficits in mice are ameliorated by subsequent subchronic administration of donepezil: Role of sigma-1 receptors
- (2009) Shinsui Kunitachi et al. BRAIN RESEARCH
- Antidepressant-like effects of cannabidiol in mice: possible involvement of 5-HT1A receptors
- (2009) TV Zanelati et al. BRITISH JOURNAL OF PHARMACOLOGY
- Agomelatine
- (2009) Maurizio Popoli CNS DRUGS
- Comparison of the mGlu5 receptor positive allosteric modulator ADX47273 and the mGlu2/3 receptor agonist LY354740 in tests for antipsychotic-like activity
- (2009) Chantal Schlumberger et al. EUROPEAN JOURNAL OF PHARMACOLOGY
- The Ubiquitin–Proteasome System Regulates the Stability of Neuronal Nicotinic Acetylcholine Receptors
- (2009) Khosrow Rezvani et al. JOURNAL OF MOLECULAR NEUROSCIENCE
- A Loss of Parvalbumin-Containing Interneurons Is Associated with Diminished Oscillatory Activity in an Animal Model of Schizophrenia
- (2009) D. J. Lodge et al. JOURNAL OF NEUROSCIENCE
- Phosphodiesterase 10A Inhibitor Activity in Preclinical Models of the Positive, Cognitive, and Negative Symptoms of Schizophrenia
- (2009) S. M. Grauer et al. JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
- Procognitive and Neuroprotective Activity of a Novel 7 Nicotinic Acetylcholine Receptor Agonist for Treatment of Neurodegenerative and Cognitive Disorders
- (2009) R. Roncarati et al. JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
- Glutamatergic (N-Methyl-D-aspartate Receptor) Hypofrontality in Schizophrenia: Too Little Juice or a Miswired Brain?
- (2009) G. J. Marek et al. MOLECULAR PHARMACOLOGY
- Dysregulation of kisspeptin and neurogenesis at adolescence link inborn immune deficits to the late onset of abnormal sensorimotor gating in congenital psychological disorders
- (2009) M Cardon et al. MOLECULAR PSYCHIATRY
- Schizophrenia-like GABAergic gene expression deficits in cerebellar Golgi cells from rats chronically exposed to low-dose phencyclidine
- (2009) W. Michael Bullock et al. NEUROCHEMISTRY INTERNATIONAL
- AC-260584, an orally bioavailable M1 muscarinic receptor allosteric agonist, improves cognitive performance in an animal model
- (2009) Stefania Risso Bradley et al. NEUROPHARMACOLOGY
- Anxiolytic- and antidepressant-like properties of ketamine in behavioral and neurophysiological animal models
- (2009) E. Engin et al. NEUROSCIENCE
- In-vivo rodent models for the experimental investigation of prenatal immune activation effects in neurodevelopmental brain disorders
- (2009) Urs Meyer et al. NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS
- Mice with genetically altered glutamate receptors as models of schizophrenia: A comprehensive review
- (2009) Dragos Inta et al. NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS
- Effects of a positive allosteric modulator of mGluR5 ADX47273 on conditioned avoidance response and PCP-induced hyperlocomotion in the rat as models for schizophrenia
- (2009) Chantal Schlumberger et al. PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR
- Disruptions in spatial working memory, but not short-term memory, induced by repeated ketamine exposure
- (2009) Takeshi Enomoto et al. PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY
- Antidepressant properties of the 5-HT4 receptor partial agonist, SL65.0155: Behavioral and neurochemical studies in rats
- (2009) Alessandra Tamburella et al. PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY
- Ketamine treatment reverses behavioral and physiological alterations induced by chronic mild stress in rats
- (2009) Lêda S.B. Garcia et al. PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY
- Activation of 5-HT6 receptors facilitates attentional set shifting
- (2009) Katherine E. Burnham et al. PSYCHOPHARMACOLOGY
- Modulation of prepulse inhibition through both M1 and M4 muscarinic receptors in mice
- (2009) Morgane Thomsen et al. PSYCHOPHARMACOLOGY
- Chronic clozapine treatment improves prenatal infection-induced working memory deficits without influencing adult hippocampal neurogenesis
- (2009) Urs Meyer et al. PSYCHOPHARMACOLOGY
- Effects of subchronic phencyclidine (PCP) treatment on social behaviors and operant discrimination and reversal learning in C57BL/6J mice
- (2009) Jonathan L. Brigman Frontiers in Behavioral Neuroscience
- Antipsychotic-like behavioral effects and cognitive enhancement by a potent and selective muscarinic M₁ receptor agonist, AC-260584.
- (2008) Kimberly E. Vanover et al. BEHAVIORAL NEUROSCIENCE
- Improvement of phencyclidine-induced social behaviour deficits in rats: Involvement of 5-HT1A receptors
- (2008) Shikha Snigdha et al. BEHAVIOURAL BRAIN RESEARCH
- Interaction of N-methyl-D-aspartate and group 5 metabotropic glutamate receptors on behavioral flexibility using a novel operant set-shift paradigm
- (2008) Justin M. Darrah et al. BEHAVIOURAL PHARMACOLOGY
- Reactivity of 5-HT 1A receptor in adult rats after neonatal noradrenergic neurons' lesion — Implications for antidepressant-like action
- (2008) Joanna Dabrowska et al. BRAIN RESEARCH
- Characterization of a CNS penetrant, selective M1muscarinic receptor agonist, 77-LH-28-1
- (2008) C J Langmead et al. BRITISH JOURNAL OF PHARMACOLOGY
- Attenuation of amphetamine-induced activity by the non-selective muscarinic receptor agonist, xanomeline, is absent in muscarinic M4 receptor knockout mice and attenuated in muscarinic M1 receptor knockout mice
- (2008) Marie L. Woolley et al. EUROPEAN JOURNAL OF PHARMACOLOGY
- Behavioral effects of dietary cholesterol in rats tested in experimental models of mild stress and cognition tasks
- (2008) Vincenzo Micale et al. EUROPEAN NEUROPSYCHOPHARMACOLOGY
- Schizophrenia: From developmental deviance to dopamine dysregulation
- (2008) Robin M. Murray et al. EUROPEAN NEUROPSYCHOPHARMACOLOGY
- Effects of microinjections of apomorphine and haloperidol into the inferior colliculus on the latent inhibition of the conditioned emotional response
- (2008) Liana L. Melo et al. EXPERIMENTAL NEUROLOGY
- Novel Selective Allosteric Activator of the M1 Muscarinic Acetylcholine Receptor Regulates Amyloid Processing and Produces Antipsychotic-Like Activity in Rats
- (2008) C. K. Jones et al. JOURNAL OF NEUROSCIENCE
- Preclinical Characterization of Selective Phosphodiesterase 10A Inhibitors: A New Therapeutic Approach to the Treatment of Schizophrenia
- (2008) C. J. Schmidt et al. JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
- Centrally Active Allosteric Potentiators of the M4 Muscarinic Acetylcholine Receptor Reverse Amphetamine-Induced Hyperlocomotor Activity in Rats
- (2008) A. E. Brady et al. JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
- Acute effects of combining citalopram and pindolol on regional brain serotonin synthesis in sham operated and olfactory bulbectomized rats
- (2008) Khanh Q. Nguyen et al. NEUROCHEMISTRY INTERNATIONAL
- Peripheral administration of group III mGlu receptor agonist ACPT-I exerts potential antipsychotic effects in rodents
- (2008) A. Pałucha-Poniewiera et al. NEUROPHARMACOLOGY
- The selective nicotinic acetylcholine receptor α7 agonist JN403 is active in animal models of cognition, sensory gating, epilepsy and pain
- (2008) Dominik Feuerbach et al. NEUROPHARMACOLOGY
- Effects of sub-anesthetic doses of ketamine on rats' spatial and non-spatial recognition memory
- (2008) N. Pitsikas et al. NEUROSCIENCE
- Behavioral effects of saredutant, a tachykinin NK2 receptor antagonist, in experimental models of mood disorders under basal and stress-related conditions
- (2008) Vincenzo Micale et al. PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR
- Social memory in mice: Disruption with an NMDA antagonist and attenuation with antipsychotic drugs
- (2008) Xue-Min Gao et al. PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR
- Tiagabine Treatment is Associated with Neurochemical, Immune and Behavioural Alterations in the Olfactory Bulbectomized Rat Model of Depression
- (2008) J. Pistovcakova et al. PHARMACOPSYCHIATRY
- Allosteric modulation of the muscarinic M4 receptor as an approach to treating schizophrenia
- (2008) W. Y. Chan et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Evaluating the antipsychotic profile of the preferential PDE10A inhibitor, papaverine
- (2008) M. Weber et al. PSYCHOPHARMACOLOGY
- Preclinical investigations into the antipsychotic potential of the novel histamine H3 receptor antagonist GSK207040
- (2008) Eric Southam et al. PSYCHOPHARMACOLOGY
- Juvenile rats in the forced-swim test model the human response to antidepressant treatment for pediatric depression
- (2008) Abbey L. Reed et al. PSYCHOPHARMACOLOGY
- Circuit-based framework for understanding neurotransmitter and risk gene interactions in schizophrenia
- (2008) John E. Lisman et al. TRENDS IN NEUROSCIENCES
- d-Serine and a glycine transporter inhibitor improve MK-801-induced cognitive deficits in a novel object recognition test in rats
- (2007) Jun-ichi Karasawa et al. BEHAVIOURAL BRAIN RESEARCH
- Increased sensitivity to antidepressants of D3 dopamine receptor-deficient mice in the forced swim test (FST)
- (2007) Gian Marco Leggio et al. EUROPEAN NEUROPSYCHOPHARMACOLOGY
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationCreate your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create Now