标题
Targeting the Glutamatergic System to Treat Major Depressive Disorder
作者
关键词
-
出版物
DRUGS
Volume 72, Issue 10, Pages 1313-1333
出版商
Springer Nature
发表日期
2012-06-27
DOI
10.2165/11633130-000000000-00000
参考文献
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注意：仅列出部分参考文献，下载原文获取全部文献信息。- Effect of co-administration of fluoxetine and amantadine on immunoendocrine parameters in rats subjected to a forced swimming test
- (2014) Zofia Rogóż et al. Pharmacological Reports
- Replication of Ketamine's Antidepressant Efficacy in Bipolar Depression: A Randomized Controlled Add-On Trial
- (2012) Carlos A. Zarate et al. BIOLOGICAL PSYCHIATRY
- Early antidepressant effect of memantine during augmentation of lamotrigine inadequate response in bipolar depression: a double-blind, randomized, placebo-controlled trial
- (2012) Amit Anand et al. BIPOLAR DISORDERS
- Ketamine for Treatment-Resistant Unipolar Depression
- (2012) Sanjay J. Mathew et al. CNS DRUGS
- Course of Improvement in Depressive Symptoms to a Single Intravenous Infusion of Ketamine vs Add-on Riluzole: Results from a 4-Week, Double-Blind, Placebo-Controlled Study
- (2012) Lobna Ibrahim et al. NEUROPSYCHOPHARMACOLOGY
- Alcohol and depression
- (2011) Joseph M. Boden et al. ADDICTION
- Trajectories of Depression Severity in Clinical Trials of Duloxetine
- (2011) Ralitza Gueorguieva ARCHIVES OF GENERAL PSYCHIATRY
- Relationship Between Genetic Variation in the Glutaminase Gene GLS1 and Brain Glutamine/Glutamate Ratio Measured In Vivo
- (2011) Dost Öngür et al. BIOLOGICAL PSYCHIATRY
- Glutamate N-methyl-D-aspartate Receptor Antagonists Rapidly Reverse Behavioral and Synaptic Deficits Caused by Chronic Stress Exposure
- (2011) Nanxin Li et al. BIOLOGICAL PSYCHIATRY
- Brain-Derived Neurotrophic Factor Val66Met Allele Impairs Basal and Ketamine-Stimulated Synaptogenesis in Prefrontal Cortex
- (2011) Rong-Jian Liu et al. BIOLOGICAL PSYCHIATRY
- Ketamine as a Novel Antidepressant: From Synapse to Behavior
- (2011) J W Murrough CLINICAL PHARMACOLOGY & THERAPEUTICS
- Inflammatory and Neurodegenerative Pathways in Depression: A New Avenue for Antidepressant Development?
- (2011) M. Catena-Dell'Osso et al. CURRENT MEDICINAL CHEMISTRY
- Investigational NMDA receptor modulators for depression
- (2011) Bernadeta Szewczyk et al. EXPERT OPINION ON INVESTIGATIONAL DRUGS
- Use of memantine for the treatment of dementia
- (2011) Daphne Lo et al. Expert Review of Neurotherapeutics
- A preliminary naturalistic study of low-dose ketamine for depression and suicide ideation in the emergency department
- (2011) Gregory Luke Larkin et al. INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY
- AMPA receptor expression is increased post-mortem samples of the anterior cingulate from subjects with major depressive disorder
- (2011) Andrew Stuart Gibbons et al. JOURNAL OF AFFECTIVE DISORDERS
- Inhibition of glycogen synthase kinase-3 is necessary for the rapid antidepressant effect of ketamine in mice
- (2011) E Beurel et al. MOLECULAR PSYCHIATRY
- NMDA receptor blockade at rest triggers rapid behavioural antidepressant responses
- (2011) Anita E. Autry et al. NATURE
- The antidepressant-like effects of glutamatergic drugs ketamine and AMPA receptor potentiator LY 451646 are preserved in bdnf+/− heterozygous null mice
- (2011) Jesse S.O. Lindholm et al. NEUROPHARMACOLOGY
- Signaling pathways underlying the rapid antidepressant actions of ketamine
- (2011) Ronald S. Duman et al. NEUROPHARMACOLOGY
- Towards a glutamate hypothesis of depression
- (2011) Gerard Sanacora et al. NEUROPHARMACOLOGY
- Mechanistic explanations how cell-mediated immune activation, inflammation and oxidative and nitrosative stress pathways and their sequels and concomitants play a role in the pathophysiology of unipolar depression
- (2011) Brian Leonard et al. NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS
- Overview of glutamatergic neurotransmission in the nervous system
- (2011) Mark J. Niciu et al. PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR
- The antidepressant effect of ketamine is not associated with changes in occipital amino acid neurotransmitter content as measured by [1H]-MRS
- (2011) Gerald W. Valentine et al. PSYCHIATRY RESEARCH-NEUROIMAGING
- Translational PK–PD modelling of molecular target modulation for the AMPA receptor positive allosteric modulator Org 26576
- (2011) Roberta Bursi et al. PSYCHOPHARMACOLOGY
- Translating Glutamate: From Pathophysiology to Treatment
- (2011) D. C. Javitt et al. Science Translational Medicine
- Regulation of neural process growth, elaboration and structural plasticity by NF-κB
- (2011) Humberto Gutierrez et al. TRENDS IN NEUROSCIENCES
- Ketamine Inhibits Transcription Factors Activator Protein 1 and Nuclear Factor-κB, Interleukin-8 Production, as well as CD11b and CD16 Expression: Studies in Human Leukocytes and Leukocytic Cell Lines
- (2010) Ingeborg D. Welters et al. ANESTHESIA AND ANALGESIA
- Stress, sex, and neural adaptation to a changing environment: mechanisms of neuronal remodeling
- (2010) Bruce S. McEwen Annals of the New York Academy of Sciences
- A Randomized Add-on Trial of an N-methyl-D-aspartate Antagonist in Treatment-Resistant Bipolar Depression
- (2010) Nancy Diazgranados et al. ARCHIVES OF GENERAL PSYCHIATRY
- Magnetic Resonance Spectroscopy Studies of the Glutamatergic System in Mood Disorders: A Pathway to Diagnosis, Novel Therapeutics, and Personalized Medicine?
- (2010) Giacomo Salvadore et al. BIOLOGICAL PSYCHIATRY
- Magnetic Resonance Spectroscopy Studies of Glutamate-Related Abnormalities in Mood Disorders
- (2010) Cagri Yüksel et al. BIOLOGICAL PSYCHIATRY
- Behavioral alterations and pro-oxidant effect of a single ketamine administration to mice
- (2010) Francisca Charliane Carlos da Silva et al. BRAIN RESEARCH BULLETIN
- Potential Psychiatric Applications of Metabotropic Glutamate Receptor Agonists and Antagonists
- (2010) John H. Krystal et al. CNS DRUGS
- If at First You Donʼt Succeed
- (2010) K. Ryan Connolly et al. DRUGS
- Efficacy of antidepressants: a re-analysis and re-interpretation of the Kirsch data
- (2010) Konstantinos N. Fountoulakis et al. INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY
- Rapid Resolution of Suicidal Ideation After a Single Infusion of anN-Methyl-D-Aspartate Antagonist in Patients With Treatment-Resistant Major Depressive Disorder
- (2010) Nancy DiazGranados et al. JOURNAL OF CLINICAL PSYCHIATRY
- A Hypothesized Role for Dendritic Remodeling in the Etiology of Mood and Anxiety Disorders
- (2010) J. M. Gorman et al. JOURNAL OF NEUROPSYCHIATRY AND CLINICAL NEUROSCIENCES
- Placebo, Prozac and PLoS: significant lessons for psychopharmacology
- (2010) Jamie Horder et al. JOURNAL OF PSYCHOPHARMACOLOGY
- Beyond the serotonin hypothesis: Mitochondria, inflammation and neurodegeneration in major depression and affective spectrum disorders
- (2010) Ann Gardner et al. PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY
- The new ‘5-HT’ hypothesis of depression: Cell-mediated immune activation induces indoleamine 2,3-dioxygenase, which leads to lower plasma tryptophan and an increased synthesis of detrimental tryptophan catabolites (TRYCATs), both of which contribute to the onset of depression
- (2010) M. Maes et al. PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY
- Chronic ketamine use increases serum levels of brain-derived neurotrophic factor
- (2010) Valerio Ricci et al. PSYCHOPHARMACOLOGY
- A Glutamate Pathway to Faster-Acting Antidepressants?
- (2010) J. F. Cryan et al. SCIENCE
- mTOR-Dependent Synapse Formation Underlies the Rapid Antidepressant Effects of NMDA Antagonists
- (2010) N. Li et al. SCIENCE
- Glutamatergic Modulators: The Future of Treating Mood Disorders?
- (2010) Carlos Zarate et al. HARVARD REVIEW OF PSYCHIATRY
- Regulation and Function of NF-κB Transcription Factors in the Immune System
- (2009) Sivakumar Vallabhapurapu et al. Annual Review of Immunology
- Effects of Intravenous Ketamine on Explicit and Implicit Measures of Suicidality in Treatment-Resistant Depression
- (2009) Rebecca B. Price et al. BIOLOGICAL PSYCHIATRY
- Safety and Efficacy of Repeated-Dose Intravenous Ketamine for Treatment-Resistant Depression
- (2009) Marije aan het Rot et al. BIOLOGICAL PSYCHIATRY
- Glycogen synthase kinase 3: more than a namesake
- (2009) Geetha Vani Rayasam et al. BRITISH JOURNAL OF PHARMACOLOGY
- Lamotrigine for treatment of bipolar depression: independent meta-analysis and meta-regression of individual patient data from five randomised trials
- (2009) John R. Geddes et al. BRITISH JOURNAL OF PSYCHIATRY
- Targeting Glutamatergic Signaling for the Development of Novel Therapeutics for Mood Disorders
- (2009) Rodrigo Machado-Vieira et al. CURRENT PHARMACEUTICAL DESIGN
- Riluzole for relapse prevention following intravenous ketamine in treatment-resistant depression: a pilot randomized, placebo-controlled continuation trial
- (2009) Sanjay J. Mathew et al. INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY
- Double-Blind, Randomized Comparison of Memantine and Escitalopram for the Treatment of Major Depressive Disorder Comorbid With Alcohol Dependence
- (2009) Leea H. Muhonen et al. JOURNAL OF CLINICAL PSYCHIATRY
- Rapid Onset of Antidepressant Action
- (2009) Rodrigo Machado-Vieira et al. JOURNAL OF CLINICAL PSYCHIATRY
- Brain-Derived Neurotrophic Factor and Initial Antidepressant Response to anN-Methyl-D-Aspartate Antagonist
- (2009) Rodrigo Machado-Vieira et al. JOURNAL OF CLINICAL PSYCHIATRY
- Anxiolytic- and antidepressant-like properties of ketamine in behavioral and neurophysiological animal models
- (2009) E. Engin et al. NEUROSCIENCE
- Brain-derived neurotrophic factor as a model system for examining gene by environment interactions across development
- (2009) B.J. Casey et al. NEUROSCIENCE
- The Role of the Tripartite Glutamatergic Synapse in the Pathophysiology and Therapeutics of Mood Disorders
- (2009) Rodrigo Machado-Vieira et al. NEUROSCIENTIST
- BDNF Activates mTOR to Regulate GluR1 Expression Required for Memory Formation
- (2009) Leandro Slipczuk et al. PLoS One
- Ketamine treatment reverses behavioral and physiological alterations induced by chronic mild stress in rats
- (2009) Lêda S.B. Garcia et al. PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY
- mTOR signaling: At the crossroads of plasticity, memory and disease
- (2009) Charles A. Hoeffer et al. TRENDS IN NEUROSCIENCES
- Adverse events associated with ketamine for procedural sedation in adults
- (2008) Reuben J. Strayer et al. AMERICAN JOURNAL OF EMERGENCY MEDICINE
- Chronic Administration of Ketamine Elicits Antidepressant-Like Effects in Rats without Affecting Hippocampal Brain-Derived Neurotrophic Factor Protein Levels
- (2008) Lêda S. Garcia et al. BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY
- Family History of Alcohol Dependence and Initial Antidepressant Response to an N -methyl-D-aspartate Antagonist
- (2008) Laura E. Phelps et al. BIOLOGICAL PSYCHIATRY
- Effect of low-dose ketamine on inflammatory response in off-pump coronary artery bypass graft surgery
- (2008) J.E. Cho et al. BRITISH JOURNAL OF ANAESTHESIA
- Riluzole in psychiatry: a systematic review of the literature
- (2008) Carlos A Zarate et al. Expert Opinion on Drug Metabolism & Toxicology
- AMPA receptor subunit 1 (GluR-A) knockout mice model the glutamate hypothesis of depression
- (2008) S. Chourbaji et al. FASEB JOURNAL
- An Innovative Design to Establish Proof of Concept of the Antidepressant Effects of the NR2B Subunit Selective N-Methyl-D-Aspartate Antagonist, CP-101,606, in Patients With Treatment-Refractory Major Depressive Disorder
- (2008) Sheldon H. Preskorn et al. JOURNAL OF CLINICAL PSYCHOPHARMACOLOGY
- The inflammatory & neurodegenerative (I&ND) hypothesis of depression: leads for future research and new drug developments in depression
- (2008) Michael Maes et al. METABOLIC BRAIN DISEASE
- The mood-improving actions of antidepressants do not depend on neurogenesis but are associated with neuronal remodeling
- (2008) J M Bessa et al. MOLECULAR PSYCHIATRY
- Targeting the glutamatergic system to develop novel, improved therapeutics for mood disorders
- (2008) Gerard Sanacora et al. NATURE REVIEWS DRUG DISCOVERY
- Stress-induced prefrontal reorganization and executive dysfunction in rodents
- (2008) Andrew Holmes et al. NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS
- Initial Severity and Antidepressant Benefits: A Meta-Analysis of Data Submitted to the Food and Drug Administration
- (2008) Irving Kirsch et al. PLOS MEDICINE
- Cellular Mechanisms Underlying the Antidepressant Effects of Ketamine: Role of α-Amino-3-Hydroxy-5-Methylisoxazole-4-Propionic Acid Receptors
- (2007) Sungho Maeng et al. BIOLOGICAL PSYCHIATRY
- Acute administration of ketamine induces antidepressant-like effects in the forced swimming test and increases BDNF levels in the rat hippocampus
- (2007) Lêda S.B. Garcia et al. PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY
- The glutamate story
- (2006) Jeffrey C Watkins et al. BRITISH JOURNAL OF PHARMACOLOGY
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