The antipsychotic-like effects of the mGlu group III orthosteric agonist, LSP1-2111, involves 5-HT1A signalling

Orthosteric versus allosteric GPCR activation: The great challenge of group-III mGluRs

(2012) Peter J. Flor et al.   BIOCHEMICAL PHARMACOLOGY

Placebo-related effects in clinical trials in schizophrenia: what is driving this phenomenon and what can be done to minimize it?

(2012) Larry Alphs et al.   INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY

The GABABreceptor agonist CGP44532 and the positive modulator GS39783 reverse some behavioural changes related to positive syndromes of psychosis in mice

(2011) JM Wierońska et al.   BRITISH JOURNAL OF PHARMACOLOGY

A Multicenter, Inpatient, Phase 2, Double-Blind, Placebo-Controlled Dose-Ranging Study of LY2140023 Monohydrate in Patients With DSM-IV Schizophrenia

(2011) Bruce J. Kinon et al.   JOURNAL OF CLINICAL PSYCHOPHARMACOLOGY

The Role of 5-Hydroxytryptamine 7 Receptors in the Phencyclidine-Induced Novel Object Recognition Deficit in Rats

(2011) M. Horiguchi et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

On the mechanism of anti-hyperthermic effects of LY379268 and LY487379, group II mGlu receptors activators, in the stress-induced hyperthermia in singly housed mice

(2011) J.M. Wierońska et al.   NEUROPHARMACOLOGY

Putative cognitive enhancers in preclinical models related to schizophrenia: The search for an elusive target

(2011) Segev Barak et al.   PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR

Opposing efficacy of group III mGlu receptor activators, LSP1-2111 and AMN082, in animal models of positive symptoms of schizophrenia

(2011) Joanna M. Wierońska et al.   PSYCHOPHARMACOLOGY

Interaction of mGlu2/3 agonism with clozapine and lurasidone to restore novel object recognition in subchronic phencyclidine-treated rats

(2011) Masakuni Horiguchi et al.   PSYCHOPHARMACOLOGY

Therapeutic Role of 5-HT1A Receptors in The Treatment of Schizophrenia and Parkinson's Disease

(2010) Yukihiro Ohno   CNS Neuroscience & Therapeutics

Effects of metabotropic glutamate receptor 2/3 agonism and antagonism on schizophrenia-like cognitive deficits induced by phencyclidine in rats

(2010) Nurith Amitai et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

The Antidepressant-Like Action of Metabotropic Glutamate 7 Receptor Agonist N,N'-Bis(Diphenylmethyl)-1,2-Ethanediamine (AMN082) Is Serotonin-Dependent

(2010) A. Palucha-Poniewiera et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Metabotropic glutamate receptor 4 novel agonist LSP1-2111 with anxiolytic, but not antidepressant-like activity, mediated by serotonergic and GABAergic systems

(2010) Joanna M. Wierońska et al.   NEUROPHARMACOLOGY

Electrophysiological and behavioral evidence that modulation of metabotropic glutamate receptor 4 with a new agonist reverses experimental parkinsonism

(2009) Corinne Beurrier et al.   FASEB JOURNAL

Unique Antipsychotic Activities of the Selective Metabotropic Glutamate Receptor 1 Allosteric Antagonist 2-Cyclopropyl-5-[1-(2-fluoro-3-pyridinyl)-5-methyl-1H-1,2,3-triazol-4-yl]-2,3-dihydro-1H-isoindol-1-one

(2009) A. Satow et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

The group III mGlu receptor agonist ACPT-I exerts anxiolytic-like but not antidepressant-like effects, mediated by the serotonergic and GABA-ergic systems

(2009) K. Stachowicz et al.   NEUROPHARMACOLOGY

Stress-induced hyperthermia is reduced by rapid-acting anxiolytic drugs independent of injection stress in rats

(2009) Christiaan H. Vinkers et al.   PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR

Combined administration of an mGlu2/3 receptor agonist and a 5-HT2A receptor antagonist markedly attenuate the psychomotor-activating and neurochemical effects of psychostimulants

(2009) Jason M. Uslaner et al.   PSYCHOPHARMACOLOGY

Stress-induced hyperthermia and basal body temperature are mediated by different 5-HT1A receptor populations: A study in SERT knockout rats

(2008) Jocelien D.A. Olivier et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Phencyclidine-induced cognitive deficits in mice are improved by subsequent subchronic administration of the antipsychotic drug perospirone: Role of serotonin 5-HT1A receptors

(2008) Hiroko Hagiwara et al.   EUROPEAN NEUROPSYCHOPHARMACOLOGY

Identification of a serotonin/glutamate receptor complex implicated in psychosis

(2008) Javier González-Maeso et al.   NATURE

Peripheral administration of group III mGlu receptor agonist ACPT-I exerts potential antipsychotic effects in rodents

(2008) A. Pałucha-Poniewiera et al.   NEUROPHARMACOLOGY

Adaptations in pre- and postsynaptic 5-HT1A receptor function and cocaine supersensitivity in serotonin transporter knockout rats

(2008) Judith R. Homberg et al.   PSYCHOPHARMACOLOGY

Activation of metabotropic glutamate receptors as a novel approach for the treatment of schizophrenia

(2008) P. Jeffrey Conn et al.   TRENDS IN PHARMACOLOGICAL SCIENCES