Knocking down cyclin D1b inhibits breast cancer cell growth and suppresses tumor development in a breast cancer model

Metformin induces unique biological and molecular responses in triple negative breast cancer cells

(2011) Bolin Liu et al.   CELL CYCLE

Knockdown of Akt isoforms by RNA silencing suppresses the growth of human prostate cancer cells in vitro and in vivo

(2010) Toyokazu Sasaki et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Strategies for In Vivo Delivery of siRNAs

(2010) Yuriko Higuchi et al.   BIODRUGS

Cyclin D1 Kinase Activity Is Required for the Self-Renewal of Mammary Stem and Progenitor Cells that Are Targets of MMTV-ErbB2 Tumorigenesis

(2010) Rinath Jeselsohn et al.   CANCER CELL

Alternative Cyclin D1 Splice Forms Differentially Regulate the DNA Damage Response

(2010) Z. Li et al.   CANCER RESEARCH

Cyclin D1/Cyclin-Dependent Kinase 4 Interacts with Filamin A and Affects the Migration and Invasion Potential of Breast Cancer Cells

(2010) Z. Zhong et al.   CANCER RESEARCH

ANCCA/ATAD2 Overexpression Identifies Breast Cancer Patients with Poor Prognosis, Acting to Drive Proliferation and Survival of Triple-Negative Cells through Control of B-Myb and EZH2

(2010) E. V. Kalashnikova et al.   CANCER RESEARCH

Drug Combination Studies and Their Synergy Quantification Using the Chou-Talalay Method

(2010) T.-C. Chou   CANCER RESEARCH

Evaluation of a 30-Gene Paclitaxel, Fluorouracil, Doxorubicin, and Cyclophosphamide Chemotherapy Response Predictor in a Multicenter Randomized Trial in Breast Cancer

(2010) A. Tabchy et al.   CLINICAL CANCER RESEARCH

The Cancer/Testis Antigen CAGE with Oncogenic Potential Stimulates Cell Proliferation by Up-regulating Cyclins D1 and E in an AP-1- and E2F-dependent Manner

(2010) Elaine Por et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Efficient inhibition of lung cancer in murine model by plasmid-encoding VEGF short hairpin RNA in combination with low-dose DDP

(2010) Yong P Ma et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

Recent Progress in Chemically Modified siRNAs

(2010) M. Gaglione et al.   MINI-REVIEWS IN MEDICINAL CHEMISTRY

Utilization of unlocked nucleic acid (UNA) to enhance siRNA performance in vitro and in vivo

(2010) Maria B. Laursen et al.   Molecular BioSystems

A Novel Plant Homeodomain Finger 10-Mediated Antiapoptotic Mechanism Involving Repression of Caspase-3 in Gastric Cancer Cells

(2010) M. Wei et al.   MOLECULAR CANCER THERAPEUTICS

MK-2206, an Allosteric Akt Inhibitor, Enhances Antitumor Efficacy by Standard Chemotherapeutic Agents or Molecular Targeted Drugs In vitro and In vivo

(2010) H. Hirai et al.   MOLECULAR CANCER THERAPEUTICS

Smart siRNA delivery systems based on polymeric nanoassemblies and nanoparticles

(2010) Atsushi Tamura et al.   Nanomedicine

A screen of chemical modifications identifies position-specific modification by UNA to most potently reduce siRNA off-target effects

(2010) Jesper B. Bramsen et al.   NUCLEIC ACIDS RESEARCH

2'-O-Methyl–Modified Anti-MDR1 Fork-siRNA Duplexes Exhibiting High Nuclease Resistance and Prolonged Silencing Activity

(2010) Natalya S. Petrova (Kruglova) et al.   OLIGONUCLEOTIDES

Lovastatin Inhibits VEGFR and AKT Activation: Synergistic Cytotoxicity in Combination with VEGFR Inhibitors

(2010) Tong T. Zhao et al.   PLoS One

Lipid-like materials for low-dose, in vivo gene silencing

(2010) K. T. Love et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Development of Lipidoid–siRNA Formulations for Systemic Delivery to the Liver

(2009) Akin Akinc et al.   MOLECULAR THERAPY

Knocking down barriers: advances in siRNA delivery

(2009) Kathryn A. Whitehead et al.   NATURE REVIEWS DRUG DISCOVERY

Cyclin D1b protein expression in breast cancer is independent of cyclin D1a and associated with poor disease outcome

(2009) E K A Millar et al.   ONCOGENE

Tissue factor/FVIIa activates Bcl-2 and prevents doxorubicin-induced apoptosis in neuroblastoma cells

(2008) Jun Fang et al.   BMC CANCER

TRAIL induces apoptosis in triple-negative breast cancer cells with a mesenchymal phenotype

(2008) Monzur Rahman et al.   BREAST CANCER RESEARCH AND TREATMENT

Cyclin D1 and CDK4 Activity Contribute to the Undifferentiated Phenotype in Neuroblastoma

(2008) J. J. Molenaar et al.   CANCER RESEARCH

Cyclin D1b Is Aberrantly Regulated in Response to Therapeutic Challenge and Promotes Resistance to Estrogen Antagonists

(2008) Y. Wang et al.   CANCER RESEARCH

Preclinicalversusclinical drug combination studies

(2008) Ting-Chao Chou   LEUKEMIA & LYMPHOMA

TRBP Control of PACT-Induced Phosphorylation of Protein Kinase R Is Reversed by Stress

(2008) A. Daher et al.   MOLECULAR AND CELLULAR BIOLOGY

Alteration of cyclin D1 transcript elongation by a mutated transcription factor up-regulates the oncogenic D1b splice isoform in cancer

(2008) G. Sanchez et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Speeding through cell cycle roadblocks: Nuclear cyclin D1-dependent kinase and neoplastic transformation

(2008) Laura L Pontano et al.   Cell Division

GSK-3β regulates cyclin D1 expression: A new target for chemotherapy

(2007) Fumi Takahashi-Yanaga et al.   CELLULAR SIGNALLING