Aging Leads to a Dysregulation in Mechanically Driven Bone Formation and Resorption

Skeletal maturity leads to a reduction in the strain magnitudes induced within the bone: A murine tibia study

(2015) Hajar Razi et al.   Acta Biomaterialia

The influence of age on adaptive bone formation and bone resorption

(2014) Annette I. Birkhold et al.   BIOMATERIALS

Aging diminishes lamellar and woven bone formation induced by tibial compression in adult C57BL/6

(2014) Nilsson Holguin et al.   BONE

Mineralizing surface is the main target of mechanical stimulation independent of age: 3D dynamic in vivo morphometry

(2014) Annette I. Birkhold et al.   BONE

Age-Related Impairment of Bones' Adaptive Response to Loading in Mice Is Associated With Sex-Related Deficiencies in Osteoblasts but No Change in Osteocytes

(2014) Lee B Meakin et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Bone remodelling in humans is load-driven but not lazy

(2014) Patrik Christen et al.   Nature Communications

Diminished response to in vivo mechanical loading in trabecular and not cortical bone in adulthood of female C57Bl/6 mice coincides with a reduction in deformation to load

(2013) Bettina M. Willie et al.   BONE

The Relevance of Mouse Models for Investigating Age-Related Bone Loss in Humans

(2013) R. L. Jilka   JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES

Epidemiology of Fracture Risk With Advancing Age

(2013) K. E. Ensrud   JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES

Age- and Menopause-Related Bone Loss Compromise Cortical and Trabecular Microstructure

(2013) E. Seeman   JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES

Local Mechanical Stimuli Regulate Bone Formation and Resorption in Mice at the Tissue Level

(2013) Friederike A. Schulte et al.   PLoS One

Coupling systems biology with multiscale mechanics, for computer simulations of bone remodeling

(2012) Stefan Scheiner et al.   COMPUTER METHODS IN APPLIED MECHANICS AND ENGINEERING

Subject-specific bone loading estimation in the human distal radius

(2012) Patrik Christen et al.   JOURNAL OF BIOMECHANICS

Bones' adaptive response to mechanical loading is essentially linear between the low strains associated with disuse and the high strains associated with the lamellar/woven bone transition

(2012) Toshihiro Sugiyama et al.   JOURNAL OF BONE AND MINERAL RESEARCH

In vivo validation of a computational bone adaptation model using open-loop control and time-lapsed micro-computed tomography

(2011) Friederike A. Schulte et al.   BONE

Tibial compression is anabolic in the adult mouse skeleton despite reduced responsiveness with aging

(2011) Maureen E. Lynch et al.   BONE

Mechanobiological regulation of the remodelling cycle in trabecular bone and possible biomechanical pathways for osteoporosis

(2010) Bríanne M. Mulvihill et al.   CLINICAL BIOMECHANICS

From Estrogen-Centric to Aging and Oxidative Stress: A Revised Perspective of the Pathogenesis of Osteoporosis

(2010) Stavros C. Manolagas   ENDOCRINE REVIEWS

Effects of aerobic training on bone mineral density of postmenopausal women

(2010) Daniel Martin et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Exercise effects on bone mass in postmenopausal women are site-specific and load-dependent

(2010) Deborah Kerr et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Aging changes mechanical loading thresholds for bone formation in rats

(2010) Charles H. Turner et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Linking functional decline of telomeres, mitochondria and stem cells during ageing

(2010) Ergün Sahin et al.   NATURE

New Suggestions for the Mechanical Control of Bone Remodeling

(2009) J. W. C. Dunlop et al.   CALCIFIED TISSUE INTERNATIONAL