Age-Related Impairment of Bones' Adaptive Response to Loading in Mice Is Associated With Sex-Related Deficiencies in Osteoblasts but No Change in Osteocytes
出版年份 2014 全文链接
标题
Age-Related Impairment of Bones' Adaptive Response to Loading in Mice Is Associated With Sex-Related Deficiencies in Osteoblasts but No Change in Osteocytes
作者
关键词
-
出版物
JOURNAL OF BONE AND MINERAL RESEARCH
Volume 29, Issue 8, Pages 1859-1871
出版商
Wiley
发表日期
2014-03-18
DOI
10.1002/jbmr.2222
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Replicatively senescent cells are arrested in G1 and G2 phases
- (2016) Zhiyong Mao et al. Aging-US
- Male mice housed in groups engage in frequent fighting and show a lower response to additional bone loading than females or individually housed males that do not fight
- (2013) Lee B. Meakin et al. BONE
- Estrogen Receptor α Mediates Proliferation of Osteoblastic Cells Stimulated by Estrogen and Mechanical Strain, but Their Acute Down-regulation of the Wnt AntagonistSostIs Mediated by Estrogen Receptor β
- (2013) Gabriel L. Galea et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Experimental and finite element analysis of strains induced by axial tibial compression in young-adult and old female C57Bl/6 mice
- (2013) Tarpit K. Patel et al. JOURNAL OF BIOMECHANICS
- Bone mechanotransduction may require augmentation in order to strengthen the senescent skeleton
- (2012) Sundar Srinivasan et al. AGEING RESEARCH REVIEWS
- High serum sclerostin predicts the occurrence of osteoporotic fractures in postmenopausal women: The center of excellence for osteoporosis research study
- (2012) Mohammed-Salleh M Ardawi et al. JOURNAL OF BONE AND MINERAL RESEARCH
- Bones' adaptive response to mechanical loading is essentially linear between the low strains associated with disuse and the high strains associated with the lamellar/woven bone transition
- (2012) Toshihiro Sugiyama et al. JOURNAL OF BONE AND MINERAL RESEARCH
- Estrogen receptor-α is required for the osteogenic response to mechanical loading in a ligand-independent manner involving its activation function 1 but not 2
- (2012) Sara H Windahl et al. JOURNAL OF BONE AND MINERAL RESEARCH
- Pathogenesis of Age-Related Bone Loss in Humans
- (2012) S. Khosla JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES
- Eroded human telomeres are more prone to remain uncapped and to trigger a G2 checkpoint response
- (2012) Laurent Jullien et al. NUCLEIC ACIDS RESEARCH
- Lrp5 Is Not Required for the Proliferative Response of Osteoblasts to Strain but Regulates Proliferation and Apoptosis in a Cell Autonomous Manner
- (2012) Behzad Javaheri et al. PLoS One
- Senescence-associated intrinsic mechanisms of osteoblast dysfunctions
- (2011) Moustapha Kassem et al. AGING CELL
- Risedronate does not reduce mechanical loading-related increases in cortical and trabecular bone mass in mice
- (2011) Toshihiro Sugiyama et al. BONE
- Sost downregulation and local Wnt signaling are required for the osteogenic response to mechanical loading
- (2011) Xiaolin Tu et al. BONE
- Loading-related Regulation of Transcription Factor EGR2/Krox-20 in Bone Cells Is ERK1/2 Protein-mediated and Prostaglandin, Wnt Signaling Pathway-, and Insulin-like Growth Factor-I Axis-dependent
- (2011) Gul Zaman et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Mechanical loading-related changes in osteocyte sclerostin expression in mice are more closely associated with the subsequent osteogenic response than the peak strains engendered
- (2011) A. Moustafa et al. OSTEOPOROSIS INTERNATIONAL
- Remodeling of Actin Cytoskeleton in Mouse Periosteal Cells under Mechanical Loading Induces Periosteal Cell Proliferation during Bone Formation
- (2011) Daisuke Sakai et al. PLoS One
- Comparing histological, vascular and molecular responses associated with woven and lamellar bone formation induced by mechanical loading in the rat ulna
- (2010) Jennifer A. McKenzie et al. BONE
- Age-Related Changes in Bone Structure and Strength in Female and Male BALB/c Mice
- (2010) Mark D. Willinghamm et al. CALCIFIED TISSUE INTERNATIONAL
- Direct transformation from quiescence to bone formation in the adult periosteum following a single brief period of bone loading
- (2010) Matthew J. Pead et al. JOURNAL OF BONE AND MINERAL RESEARCH
- Exercise effects on bone mass in postmenopausal women are site-specific and load-dependent
- (2010) Deborah Kerr et al. JOURNAL OF BONE AND MINERAL RESEARCH
- Aging changes mechanical loading thresholds for bone formation in rats
- (2010) Charles H. Turner et al. JOURNAL OF BONE AND MINERAL RESEARCH
- Aged mice have enhanced endocortical response and normal periosteal response compared with young-adult mice following 1 week of axial tibial compression
- (2010) Michael D Brodt et al. JOURNAL OF BONE AND MINERAL RESEARCH
- Guidelines for assessment of bone microstructure in rodents using micro-computed tomography
- (2010) Mary L Bouxsein et al. JOURNAL OF BONE AND MINERAL RESEARCH
- Reprogramming the pluripotent cell cycle: Restoration of an abbreviated G1 phase in human induced pluripotent stem (iPS) cells
- (2010) Prachi N. Ghule et al. JOURNAL OF CELLULAR PHYSIOLOGY
- Effects of a 1-year randomized controlled trial of resistance training on lower limb bone and muscle structure and function in older men
- (2010) J. Whiteford et al. OSTEOPOROSIS INTERNATIONAL
- Endogenous glucocorticoids decrease skeletal angiogenesis, vascularity, hydration, and strength in aged mice
- (2009) Robert S. Weinstein et al. AGING CELL
- Loading-related regulation of gene expression in bone in the contexts of estrogen deficiency, lack of estrogen receptor α and disuse
- (2009) Gul Zaman et al. BONE
- Functional adaptation to mechanical loading in both cortical and cancellous bone is controlled locally and is confined to the loaded bones
- (2009) Toshihiro Sugiyama et al. BONE
- The Matricellular Protein Periostin Is Required forSostInhibition and the Anabolic Response to Mechanical Loading and Physical Activity
- (2009) Nicolas Bonnet et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Mechano-transduction in Osteoblastic Cells Involves Strain-regulated Estrogen Receptor α-mediated Control of Insulin-like Growth Factor (IGF) I Receptor Sensitivity to Ambient IGF, Leading to Phosphatidylinositol 3-Kinase/AKT-dependent Wnt/LRP5 Receptor-independent Activation of β-Catenin Signaling
- (2009) Andrew Sunters et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Mechanical loading enhances the anabolic effects of intermittent parathyroid hormone (1–34) on trabecular and cortical bone in mice
- (2008) Toshihiro Sugiyama et al. BONE
Become a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get StartedAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started