标题
Targeting pericytes for therapeutic approaches to neurological disorders
作者
关键词
Pericyte, Capillary, Blood–brain barrier, Ischaemia, Alzheimer’s, Spinal cord injury, Diabetes
出版物
ACTA NEUROPATHOLOGICA
Volume -, Issue -, Pages -
出版商
Springer Nature America, Inc
发表日期
2018-08-10
DOI
10.1007/s00401-018-1893-0
参考文献
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Active role of capillary pericytes during stimulation-induced activity and spreading depolarization
- (2018) Lila Khennouf et al. BRAIN
- Defining the ionic mechanisms of optogenetic control of vascular tone by channelrhodopsin-2
- (2018) Nils J G Rorsman et al. BRITISH JOURNAL OF PHARMACOLOGY
- Reducing Pericyte-Derived Scarring Promotes Recovery after Spinal Cord Injury
- (2018) David Oliveira Dias et al. CELL
- Brain pericyte activation occurs early in Huntington's disease
- (2018) Thomas Padel et al. EXPERIMENTAL NEUROLOGY
- β-Adrenergic receptor agonists attenuate pericyte loss in diabetic retinas through Akt activation
- (2018) Jang-Hyuk Yun et al. FASEB JOURNAL
- PDGFR-β restores blood-brain barrier functions in a mouse model of focal cerebral ischemia
- (2018) Jie Shen et al. JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM
- Crossing the blood-brain barrier with nanoparticles
- (2018) Yiqun Zhou et al. JOURNAL OF CONTROLLED RELEASE
- Vascular Compartmentalization of Functional Hyperemia from the Synapse to the Pia
- (2018) Ravi L. Rungta et al. NEURON
- Topographic Reorganization of Cerebrovascular Mural Cells under Seizure Conditions
- (2018) Margarita Arango-Lievano et al. Cell Reports
- Dynamic Remodeling of Pericytes In Vivo Maintains Capillary Coverage in the Adult Mouse Brain
- (2018) Andrée-Anne Berthiaume et al. Cell Reports
- Capillary pericytes express α-smooth muscle actin, which requires prevention of filamentous-actin depolymerization for detection
- (2018) Luis Alarcon-Martinez et al. eLife
- A molecular atlas of cell types and zonation in the brain vasculature
- (2018) Michael Vanlandewijck et al. NATURE
- Organizational hierarchy and structural diversity of microvascular pericytes in adult mouse cortex
- (2017) Roger I Grant et al. JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM
- Pericytes secrete pro-regenerative molecules in response to platelet-derived growth factor-BB
- (2017) Abderahim Gaceb et al. JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM
- Proliferating NG2-Cell-Dependent Angiogenesis and Scar Formation Alter Axon Growth and Functional Recovery After Spinal Cord Injury in Mice
- (2017) Zoe C. Hesp et al. JOURNAL OF NEUROSCIENCE
- Loss of Pericytes in Radiation Necrosis after Glioblastoma Treatments
- (2017) Soon-Tae Lee et al. MOLECULAR NEUROBIOLOGY
- Pericytes impair capillary blood flow and motor function after chronic spinal cord injury
- (2017) Yaqing Li et al. NATURE MEDICINE
- A fluoro-Nissl dye identifies pericytes as distinct vascular mural cells during in vivo brain imaging
- (2017) Eyiyemisi C Damisah et al. NATURE NEUROSCIENCE
- Pericyte degeneration leads to neurovascular uncoupling and limits oxygen supply to brain
- (2017) Kassandra Kisler et al. NATURE NEUROSCIENCE
- Cerebral blood flow regulation and neurovascular dysfunction in Alzheimer disease
- (2017) Kassandra Kisler et al. NATURE REVIEWS NEUROSCIENCE
- Gradual Suppression of Transcytosis Governs Functional Blood-Retinal Barrier Formation
- (2017) Brian Wai Chow et al. NEURON
- Brain Pericytes As Mediators of Neuroinflammation
- (2017) Justin Rustenhoven et al. TRENDS IN PHARMACOLOGICAL SCIENCES
- Plastic roles of pericytes in the blood–retinal barrier
- (2017) Do Young Park et al. Nature Communications
- Pericyte-expressed Tie2 controls angiogenesis and vessel maturation
- (2017) Martin Teichert et al. Nature Communications
- Role of Delta-like 4 in Jagged1-induced tumour angiogenesis and tumour growth
- (2017) Chern Ein Oon et al. Oncotarget
- Pericytes Stimulate Oligodendrocyte Progenitor Cell Differentiation during CNS Remyelination
- (2017) Alerie Guzman De La Fuente et al. Cell Reports
- Capillary pericytes mediate coronary no-reflow after myocardial ischaemia
- (2017) Fergus M O'Farrell et al. eLife
- Abnormal Capillary Vasodynamics Contribute to Ictal Neurodegeneration in Epilepsy
- (2017) Rocio Leal-Campanario et al. Scientific Reports
- The capillary bed offers the largest hemodynamic resistance to the cortical blood supply
- (2016) Ian Gopal Gould et al. JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM
- Glial Cell Calcium Signaling Mediates Capillary Regulation of Blood Flow in the Retina
- (2016) Kyle R. Biesecker et al. JOURNAL OF NEUROSCIENCE
- Astrocyte scar formation aids central nervous system axon regeneration
- (2016) Mark A. Anderson et al. NATURE
- Endothelial exocytosis of angiopoietin-2 resulting from CCM3 deficiency contributes to cerebral cavernous malformation
- (2016) Huanjiao Jenny Zhou et al. NATURE MEDICINE
- Astrocytes mediate neurovascular signaling to capillary pericytes but not to arterioles
- (2016) Anusha Mishra et al. NATURE NEUROSCIENCE
- Pericytes of the neurovascular unit: key functions and signaling pathways
- (2016) Melanie D Sweeney et al. NATURE NEUROSCIENCE
- Platelet-derived growth factor-BB has neurorestorative effects and modulates the pericyte response in a partial 6-hydroxydopamine lesion mouse model of Parkinson's disease
- (2016) Thomas Padel et al. NEUROBIOLOGY OF DISEASE
- Plasmalemma vesicle-associated protein: A crucial component of vascular homeostasis
- (2016) Ling Guo et al. Experimental and Therapeutic Medicine
- The PDGF-BB-SOX7 axis-modulated IL-33 in pericytes and stromal cells promotes metastasis through tumour-associated macrophages
- (2016) Yunlong Yang et al. Nature Communications
- Early role of vascular dysregulation on late-onset Alzheimer’s disease based on multifactorial data-driven analysis
- (2016) Y. Iturria-Medina et al. Nature Communications
- Analysis of the brain mural cell transcriptome
- (2016) Liqun He et al. Scientific Reports
- Pericytes are involved in the pathogenesis of cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy
- (2015) Mitrajit Ghosh et al. ANNALS OF NEUROLOGY
- Cerebrovascular and blood-brain barrier impairments in Huntington's disease: Potential implications for its pathophysiology
- (2015) Janelle Drouin-Ouellet et al. ANNALS OF NEUROLOGY
- Aberrant astrocytes impair vascular reactivity in Huntington disease
- (2015) Han-Yun Hsiao et al. ANNALS OF NEUROLOGY
- Prostacyclin Prevents Pericyte Loss and Demyelination Induced by Lysophosphatidylcholine in the Central Nervous System
- (2015) Rieko Muramatsu et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- What is a pericyte?
- (2015) David Attwell et al. JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM
- Safety and tolerability of intracerebroventricular PDGF-BB in Parkinson’s disease patients
- (2015) Gesine Paul et al. JOURNAL OF CLINICAL INVESTIGATION
- The endothelial protein PLVAP in lymphatics controls the entry of lymphocytes and antigens into lymph nodes
- (2015) Pia Rantakari et al. NATURE IMMUNOLOGY
- Hematogenous macrophage depletion reduces the fibrotic scar and increases axonal growth after spinal cord injury
- (2015) Y. Zhu et al. NEUROBIOLOGY OF DISEASE
- Blood-Brain Barrier Breakdown in the Aging Human Hippocampus
- (2015) Axel Montagne et al. NEURON
- Regional Blood Flow in the Normal and Ischemic Brain Is Controlled by Arteriolar Smooth Muscle Cell Contractility and Not by Capillary Pericytes
- (2015) Robert A. Hill et al. NEURON
- Shedding of soluble platelet-derived growth factor receptor-β from human brain pericytes
- (2015) Abhay P. Sagare et al. NEUROSCIENCE LETTERS
- Brain Vascular Pericytes Following Ischemia Have Multipotential Stem Cell Activity to Differentiate Into Neural and Vascular Lineage Cells
- (2015) Takayuki Nakagomi et al. STEM CELLS
- Cerebral Cavernous Malformation-1 Protein Controls DLL4-Notch3 Signaling Between the Endothelium and Pericytes
- (2015) G. B. Schulz et al. STROKE
- Combined deficiency of Notch1 and Notch3 causes pericyte dysfunction, models CADASIL and results in arteriovenous malformations
- (2015) Natalie M. Kofler et al. Scientific Reports
- Pericyte structure and distribution in the cerebral cortex revealed by high-resolution imaging of transgenic mice
- (2015) David A. Hartmann et al. Neurophotonics
- Endogenous Brain Pericytes Are Widely Activated and Contribute to Mouse Glioma Microvasculature
- (2015) Andreas Svensson et al. PLoS One
- Brain pericytes acquire a microglial phenotype after stroke
- (2014) Ilknur Özen et al. ACTA NEUROPATHOLOGICA
- Retinal Microangiopathy in a Mouse Model of Inducible Mural Cell Loss
- (2014) Cammi N. Valdez et al. AMERICAN JOURNAL OF PATHOLOGY
- Angiopoietin 2 Induces Pericyte Apoptosis via 3 1 Integrin Signaling in Diabetic Retinopathy
- (2014) S. W. Park et al. DIABETES
- Thalidomide Ameliorates Inflammation and Vascular Injury but Aggravates Tubular Damage in the Irradiated Mouse Kidney
- (2014) Marion Scharpfenecker et al. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS
- Capillary Transit Time Heterogeneity and Flow-Metabolism Coupling after Traumatic Brain Injury
- (2014) Leif Østergaard et al. JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM
- A role for human brain pericytes in neuroinflammation
- (2014) Deidre Jansson et al. Journal of Neuroinflammation
- An RNA-Sequencing Transcriptome and Splicing Database of Glia, Neurons, and Vascular Cells of the Cerebral Cortex
- (2014) Y. Zhang et al. JOURNAL OF NEUROSCIENCE
- Pericyte Dynamics during Angiogenesis: New Insights from New Identities
- (2014) Peter C. Stapor et al. JOURNAL OF VASCULAR RESEARCH
- Cilostazol attenuates ischemia–reperfusion-induced blood–brain barrier dysfunction enhanced by advanced glycation endproducts via transforming growth factor-β1 signaling
- (2014) Tomonori Takeshita et al. MOLECULAR AND CELLULAR NEUROSCIENCE
- Mfsd2a is critical for the formation and function of the blood–brain barrier
- (2014) Ayal Ben-Zvi et al. NATURE
- Capillary pericytes regulate cerebral blood flow in health and disease
- (2014) Catherine N. Hall et al. NATURE
- Squalenoyl adenosine nanoparticles provide neuroprotection after stroke and spinal cord injury
- (2014) Alice Gaudin et al. Nature Nanotechnology
- Redistribution of PDGFRβ cells and NG2DsRed pericytes at the cerebrovasculature after status epilepticus
- (2014) Sebastien Milesi et al. NEUROBIOLOGY OF DISEASE
- Anatomical and functional evidence for trace amines as unique modulators of locomotor function in the mammalian spinal cord
- (2014) Elizabeth A. Gozal et al. Frontiers in Neural Circuits
- Neurological deficits caused by tissue hypoxia in neuroinflammatory disease
- (2013) Andrew L. Davies et al. ANNALS OF NEUROLOGY
- Imatinib disrupts lymphoma angiogenesis by targeting vascular pericytes
- (2013) J. Ruan et al. BLOOD
- Glioblastoma Stem Cells Generate Vascular Pericytes to Support Vessel Function and Tumor Growth
- (2013) Lin Cheng et al. CELL
- Notch3 establishes brain vascular integrity by regulating pericyte number
- (2013) Y. Wang et al. DEVELOPMENT
- Hyperglycaemia promotes cerebral barrier dysfunction through activation of protein kinase C-β
- (2013) B. Shao et al. DIABETES OBESITY & METABOLISM
- The Role of the Microcirculation in Delayed Cerebral Ischemia and Chronic Degenerative Changes after Subarachnoid Hemorrhage
- (2013) Leif Østergaard et al. JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM
- Increased 20-HETE Synthesis Explains Reduced Cerebral Blood Flow But Not Impaired Neurovascular Coupling after Cortical Spreading Depression in Rat Cerebral Cortex
- (2013) J. C. Fordsmann et al. JOURNAL OF NEUROSCIENCE
- Glial Scar Borders Are Formed by Newly Proliferated, Elongated Astrocytes That Interact to Corral Inflammatory and Fibrotic Cells via STAT3-Dependent Mechanisms after Spinal Cord Injury
- (2013) I. B. Wanner et al. JOURNAL OF NEUROSCIENCE
- How Do Immune Cells Support and Shape the Brain in Health, Disease, and Aging?
- (2013) M. Schwartz et al. JOURNAL OF NEUROSCIENCE
- Neurovascular protection of cilostazol in stroke-prone spontaneous hypertensive rats associated with angiogenesis and pericyte proliferation
- (2013) Yoshio Omote et al. JOURNAL OF NEUROSCIENCE RESEARCH
- EndMT contributes to the onset and progression of cerebral cavernous malformations
- (2013) Luigi Maddaluno et al. NATURE
- Mutations in the gene encoding PDGF-B cause brain calcifications in humans and mice
- (2013) Annika Keller et al. NATURE GENETICS
- Advanced glycation end-products disrupt the blood–brain barrier by stimulating the release of transforming growth factor–β by pericytes and vascular endothelial growth factor and matrix metalloproteinase–2 by endothelial cells in vitro
- (2013) Fumitaka Shimizu et al. NEUROBIOLOGY OF AGING
- A Novel In Vitro Model to Study Pericytes in the Neurovascular Unit of the Developing Cortex
- (2013) Christoph M. Zehendner et al. PLoS One
- Coronary Microvascular Pericytes Are the Cellular Target of Sunitinib Malate-Induced Cardiotoxicity
- (2013) V. Chintalgattu et al. Science Translational Medicine
- Vascular Endothelial Growth Factor Promotes Pericyte Coverage of Brain Capillaries, Improves Cerebral Blood Flow During Subsequent Focal Cerebral Ischemia, and Preserves the Metabolic Penumbra
- (2013) Anil Zechariah et al. STROKE
- Pericyte loss influences Alzheimer-like neurodegeneration in mice
- (2013) Abhay P. Sagare et al. Nature Communications
- Blood–spinal cord barrier breakdown and pericyte reductions in amyotrophic lateral sclerosis
- (2012) Ethan A. Winkler et al. ACTA NEUROPATHOLOGICA
- Deficiency in Mural Vascular Cells Coincides with Blood-Brain Barrier Disruption in Alzheimer's Disease
- (2012) Jesse D. Sengillo et al. BRAIN PATHOLOGY
- Reprogramming of Pericyte-Derived Cells of the Adult Human Brain into Induced Neuronal Cells
- (2012) Marisa Karow et al. Cell Stem Cell
- Early Loss of Pericytes and Perivascular Stromal Cell-Induced Scar Formation after Stroke
- (2012) Francisco Fernández-Klett et al. JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM
- Pericytes support neutrophil subendothelial cell crawling and breaching of venular walls in vivo
- (2012) Doris Proebstl et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Neural Progenitor Cells Regulate Capillary Blood Flow in the Postnatal Subventricular Zone
- (2012) B. Lacar et al. JOURNAL OF NEUROSCIENCE
- Capillary and arteriolar pericytes attract innate leukocytes exiting through venules and 'instruct' them with pattern-recognition and motility programs
- (2012) Konstantin Stark et al. NATURE IMMUNOLOGY
- Mutation of the PDGFRB gene as a cause of idiopathic basal ganglia calcification
- (2012) G. Nicolas et al. NEUROLOGY
- Evaluation of a Previously Suggested Plasma Biomarker Panel to Identify Alzheimer's Disease
- (2012) Maria Björkqvist et al. PLoS One
- Functional expression of P2X4 receptor in capillary endothelial cells of the cochlear spiral ligament and its role in regulating the capillary diameter
- (2011) T. Wu et al. AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY
- Lactate dilates cochlear capillaries via type V fibrocyte-vessel coupling signaled by nNOS
- (2011) Min Dai et al. AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY
- Spreading depolarizations have prolonged direct current shifts and are associated with poor outcome in brain trauma
- (2011) Jed A. Hartings et al. BRAIN
- Endothelial Smad4 Maintains Cerebrovascular Integrity by Activating N-Cadherin through Cooperation with Notch
- (2011) Fangfei Li et al. DEVELOPMENTAL CELL
- Pericytes: Developmental, Physiological, and Pathological Perspectives, Problems, and Promises
- (2011) Annika Armulik et al. DEVELOPMENTAL CELL
- Central nervous system pericytes in health and disease
- (2011) Ethan A Winkler et al. NATURE NEUROSCIENCE
- Angiopoietin/Tie2 pathway mediates type 2 diabetes induced vascular damage after cerebral stroke
- (2011) Xu Cui et al. NEUROBIOLOGY OF DISEASE
- A Pericyte Origin of Spinal Cord Scar Tissue
- (2011) C. Goritz et al. SCIENCE
- The 140-kDa Protein of Blood-Brain Barrier-Associated Pericytes Is Identical to Aminopeptidase N
- (2010) Jörg Kunz et al. JOURNAL OF NEUROCHEMISTRY
- Glial and neuronal control of brain blood flow
- (2010) David Attwell et al. NATURE
- Pericytes regulate the blood–brain barrier
- (2010) Annika Armulik et al. NATURE
- Pericytes are required for blood–brain barrier integrity during embryogenesis
- (2010) Richard Daneman et al. NATURE
- Thalidomide stimulates vessel maturation and reduces epistaxis in individuals with hereditary hemorrhagic telangiectasia
- (2010) Franck Lebrin et al. NATURE MEDICINE
- Pericytes Control Key Neurovascular Functions and Neuronal Phenotype in the Adult Brain and during Brain Aging
- (2010) Robert D. Bell et al. NEURON
- Effect of Prenatal Glucocorticoids on Cerebral Vasculature of the Developing Brain
- (2010) Govindaiah Vinukonda et al. STROKE
- CNS pericytes: Concepts, misconceptions, and a way out
- (2009) Martin Krueger et al. GLIA
- Pericyte contraction induced by oxidative-nitrative stress impairs capillary reflow despite successful opening of an occluded cerebral artery
- (2009) Muge Yemisci et al. NATURE MEDICINE
- Activation of PKC-δ and SHP-1 by hyperglycemia causes vascular cell apoptosis and diabetic retinopathy
- (2009) Pedro Geraldes et al. NATURE MEDICINE
- Endosialin (Tem1) Is a Marker of Tumor-Associated Myofibroblasts and Tumor Vessel-Associated Mural Cells
- (2008) Sven Christian et al. AMERICAN JOURNAL OF PATHOLOGY
- Angiopoietin-1 promotes endothelial cell proliferation and migration through AP-1-dependent autocrine production of interleukin-8
- (2008) N. A. Abdel-Malak et al. BLOOD
- Pericytes: Pluripotent Cells of the Blood Brain Barrier
- (2008) Paula Dore-Duffy CURRENT PHARMACEUTICAL DESIGN
- Thalidomide inhibition of perturbed vasculature and glial-derived tumor necrosis factor-α in an animal model of inflamed Alzheimer’s disease brain
- (2007) Jae K. Ryu et al. NEUROBIOLOGY OF DISEASE
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