标题
The emerging roles of the STING adaptor protein in immunity and diseases
作者
关键词
-
出版物
IMMUNOLOGY
Volume 147, Issue 3, Pages 285-291
出版商
Wiley
发表日期
2015-12-09
DOI
10.1111/imm.12561
参考文献
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Nucleic Acid Recognition Orchestrates the Anti-Viral Response to Retroviruses
- (2015) Spyridon Stavrou et al. Cell Host & Microbe
- The Cytosolic Sensor cGAS Detects Mycobacterium tuberculosis DNA to Induce Type I Interferons and Activate Autophagy
- (2015) Robert O. Watson et al. Cell Host & Microbe
- Mycobacterium tuberculosis Differentially Activates cGAS- and Inflammasome-Dependent Intracellular Immune Responses through ESX-1
- (2015) Ruth Wassermann et al. Cell Host & Microbe
- Sensing and responding to cytosolic viruses invasions: An orchestra of kaleidoscopic ubiquitinations
- (2015) Xing Liu et al. CYTOKINE & GROWTH FACTOR REVIEWS
- Cytosolic Nuclease TREX1 Regulates Oligosaccharyltransferase Activity Independent of Nuclease Activity to Suppress Immune Activation
- (2015) Maroof Hasan et al. IMMUNITY
- DNA Damage Primes the Type I Interferon System via the Cytosolic DNA Sensor STING to Promote Anti-Microbial Innate Immunity
- (2015) Anetta Härtlova et al. IMMUNITY
- DNA tumor virus oncogenes antagonize the cGAS-STING DNA-sensing pathway
- (2015) L. Lau et al. SCIENCE
- Bacterial c-di-GMP Affects Hematopoietic Stem/Progenitors and Their Niches through STING
- (2015) Hiroshi Kobayashi et al. Cell Reports
- Genome-wide Analysis of Host-Plasmodium yoelii Interactions Reveals Regulators of the Type I Interferon Response
- (2015) Jian Wu et al. Cell Reports
- DDX60 Is Involved in RIG-I-Dependent and Independent Antiviral Responses, and Its Function Is Attenuated by Virus-Induced EGFR Activation
- (2015) Hiroyuki Oshiumi et al. Cell Reports
- Genome-Derived Cytosolic DNA Mediates Type I Interferon-Dependent Rejection of B Cell Lymphoma Cells
- (2015) Yu J. Shen et al. Cell Reports
- Bruton’s Tyrosine Kinase Phosphorylates DDX41 and Activates Its Binding of dsDNA and STING to Initiate Type 1 Interferon Response
- (2015) Koon-Guan Lee et al. Cell Reports
- Direct Activation of STING in the Tumor Microenvironment Leads to Potent and Systemic Tumor Regression and Immunity
- (2015) Leticia Corrales et al. Cell Reports
- Herpesvirus Genome Recognition Induced Acetylation of Nuclear IFI16 Is Essential for Its Cytoplasmic Translocation, Inflammasome and IFN-β Responses
- (2015) Mairaj Ahmed Ansari et al. PLoS Pathogens
- The ER-Associated Protein ZDHHC1 Is a Positive Regulator of DNA Virus-Triggered, MITA/STING-Dependent Innate Immune Signaling
- (2014) Qian Zhou et al. Cell Host & Microbe
- Role of DNA/RNA sensors and contribution to autoimmunity
- (2014) Siobhán Smith et al. CYTOKINE & GROWTH FACTOR REVIEWS
- RIG-I-like receptors and negative-strand RNA viruses: RLRly bird catches some worms
- (2014) Michaela Weber et al. CYTOKINE & GROWTH FACTOR REVIEWS
- The E3 Ubiquitin Ligase AMFR and INSIG1 Bridge the Activation of TBK1 Kinase by Modifying the Adaptor STING
- (2014) Qiang Wang et al. IMMUNITY
- STING-Dependent Cytosolic DNA Sensing Mediates Innate Immune Recognition of Immunogenic Tumors
- (2014) Seng-Ryong Woo et al. IMMUNITY
- STING-Dependent Cytosolic DNA Sensing Promotes Radiation-Induced Type I Interferon-Dependent Antitumor Immunity in Immunogenic Tumors
- (2014) Liufu Deng et al. IMMUNITY
- Adding to the STING
- (2014) Hong-Bing Shu et al. IMMUNITY
- NLRC3, a Member of the NLR Family of Proteins, Is a Negative Regulator of Innate Immune Signaling Induced by the DNA Sensor STING
- (2014) Lu Zhang et al. IMMUNITY
- TREX1 Deficiency Triggers Cell-Autonomous Immunity in a cGAS-Dependent Manner
- (2014) A. Ablasser et al. JOURNAL OF IMMUNOLOGY
- Binding-Pocket and Lid-Region Substitutions Render Human STING Sensitive to the Species-Specific Drug DMXAA
- (2014) Pu Gao et al. Cell Reports
- Dnase2a Deficiency Uncovers Lysosomal Clearance of Damaged Nuclear DNA via Autophagy
- (2014) Yuk Yuen Lan et al. Cell Reports
- Modified Vaccinia Virus Ankara Triggers Type I IFN Production in Murine Conventional Dendritic Cells via a cGAS/STING-Mediated Cytosolic DNA-Sensing Pathway
- (2014) Peihong Dai et al. PLoS Pathogens
- STING-Dependent Type I IFN Production Inhibits Cell-Mediated Immunity to Listeria monocytogenes
- (2014) Kristina A. Archer et al. PLoS Pathogens
- RNF26 Temporally Regulates Virus-Triggered Type I Interferon Induction by Two Distinct Mechanisms
- (2014) Yue Qin et al. PLoS Pathogens
- Structure-Function Analysis of STING Activation by c[G(2′,5′)pA(3′,5′)p] and Targeting by Antiviral DMXAA
- (2013) Pu Gao et al. CELL
- Cyclic [G(2′,5′)pA(3′,5′)p] Is the Metazoan Second Messenger Produced by DNA-Activated Cyclic GMP-AMP Synthase
- (2013) Pu Gao et al. CELL
- Cyclic Dinucleotides Trigger ULK1 (ATG1) Phosphorylation of STING to Prevent Sustained Innate Immune Signaling
- (2013) Hiroyasu Konno et al. CELL
- Dynamic regulation of innate immunity by ubiquitin and ubiquitin-like proteins
- (2013) Xing Liu et al. CYTOKINE & GROWTH FACTOR REVIEWS
- Species-specific detection of the antiviral small-molecule compound CMA by STING
- (2013) Taner Cavlar et al. EMBO JOURNAL
- Oxidative Damage of DNA Confers Resistance to Cytosolic Nuclease TREX1 Degradation and Potentiates STING-Dependent Immune Sensing
- (2013) Nadine Gehrke et al. IMMUNITY
- Immune Sensing of DNA
- (2013) Søren R. Paludan et al. IMMUNITY
- In SilicoScreening for Palmitoyl Substrates Reveals a Role for DHHC1/3/10 (zDHHC1/3/11)-mediated Neurochondrin Palmitoylation in Its Targeting to Rab5-positive Endosomes
- (2013) Shinichiro Oku et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Hepatitis C virus NS4B blocks the interaction of STING and TBK1 to evade host innate immunity
- (2013) Qiang Ding et al. JOURNAL OF HEPATOLOGY
- Cyclic GMP-AMP Containing Mixed Phosphodiester Linkages Is An Endogenous High-Affinity Ligand for STING
- (2013) Xu Zhang et al. MOLECULAR CELL
- cGAS produces a 2′-5′-linked cyclic dinucleotide second messenger that activates STING
- (2013) Andrea Ablasser et al. NATURE
- Pivotal Roles of cGAS-cGAMP Signaling in Antiviral Defense and Immune Adjuvant Effects
- (2013) X.-D. Li et al. SCIENCE
- The Innate Immune DNA Sensor cGAS Produces a Noncanonical Cyclic Dinucleotide that Activates Human STING
- (2013) Elie J. Diner et al. Cell Reports
- Negative Regulation of TLR Inflammatory Signaling by the SUMO-deconjugating Enzyme SENP6
- (2013) Xing Liu et al. PLoS Pathogens
- Hepatitis C virus NS4B protein targets STING and abrogates RIG-I-mediated type I interferon-dependent innate immunity
- (2012) Sayuri Nitta et al. HEPATOLOGY
- Structural Analysis of the STING Adaptor Protein Reveals a Hydrophobic Dimer Interface and Mode of Cyclic di-GMP Binding
- (2012) Songying Ouyang et al. IMMUNITY
- Autoimmunity Initiates in Nonhematopoietic Cells and Progresses via Lymphocytes in an Interferon-Dependent Autoimmune Disease
- (2012) Alevtina Gall et al. IMMUNITY
- TRIM32 Protein Modulates Type I Interferon Induction and Cellular Antiviral Response by Targeting MITA/STING Protein for K63-linked Ubiquitination
- (2012) Jing Zhang et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Cyclic di-GMP Sensing via the Innate Immune Signaling Protein STING
- (2012) Qian Yin et al. MOLECULAR CELL
- Structure of STING bound to cyclic di-GMP reveals the mechanism of cyclic dinucleotide recognition by the immune system
- (2012) Chang Shu et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- The structural basis for the sensing and binding of cyclic di-GMP by STING
- (2012) Yi-He Huang et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Crystal structures of STING protein reveal basis for recognition of cyclic di-GMP
- (2012) Guijun Shang et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- STING manifests self DNA-dependent inflammatory disease
- (2012) J. Ahn et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Cyclic GMP-AMP Synthase Is a Cytosolic DNA Sensor That Activates the Type I Interferon Pathway
- (2012) L. Sun et al. SCIENCE
- STING Specifies IRF3 Phosphorylation by TBK1 in the Cytosolic DNA Signaling Pathway
- (2012) Y. Tanaka et al. Science Signaling
- Dengue Virus Targets the Adaptor Protein MITA to Subvert Host Innate Immunity
- (2012) Chia-Yi Yu et al. PLoS Pathogens
- DENV Inhibits Type I IFN Production in Infected Cells by Cleaving Human STING
- (2012) Sebastian Aguirre et al. PLoS Pathogens
- Orchestrating the interferon antiviral response through the mitochondrial antiviral signaling (MAVS) adapter
- (2011) S Mehdi Belgnaoui et al. CURRENT OPINION IN IMMUNOLOGY
- Immune Signaling by RIG-I-like Receptors
- (2011) Yueh-Ming Loo et al. IMMUNITY
- Innate Immune Recognition of an AT-Rich Stem-Loop DNA Motif in the Plasmodium falciparum Genome
- (2011) Shruti Sharma et al. IMMUNITY
- STING is a direct innate immune sensor of cyclic di-GMP
- (2011) Dara L. Burdette et al. NATURE
- The helicase DDX41 senses intracellular DNA mediated by the adaptor STING in dendritic cells
- (2011) Zhiqiang Zhang et al. NATURE IMMUNOLOGY
- Mitochondrial Ubiquitin Ligase MARCH5 Promotes TLR7 Signaling by Attenuating TANK Action
- (2011) He-Xin Shi et al. PLoS Pathogens
- Pattern Recognition Receptors and Inflammation
- (2010) Osamu Takeuchi et al. CELL
- The Ubiquitin Ligase TRIM56 Regulates Innate Immune Responses to Intracellular Double-Stranded DNA
- (2010) Tetsuo Tsuchida et al. IMMUNITY
- TheN-Ethyl-N-Nitrosourea-InducedGoldenticketMouse Mutant Reveals an Essential Function ofStingin theIn VivoInterferon Response toListeria monocytogenesand Cyclic Dinucleotides
- (2010) John-Demian Sauer et al. INFECTION AND IMMUNITY
- Positive Regulation of Interferon Regulatory Factor 3 Activation by Herc5 via ISG15 Modification
- (2010) H. X. Shi et al. MOLECULAR AND CELLULAR BIOLOGY
- IFI16 is an innate immune sensor for intracellular DNA
- (2010) Leonie Unterholzner et al. NATURE IMMUNOLOGY
- c-di-AMP Secreted by Intracellular Listeria monocytogenes Activates a Host Type I Interferon Response
- (2010) J. J. Woodward et al. SCIENCE
- The Ubiquitin Ligase RNF5 Regulates Antiviral Responses by Mediating Degradation of the Adaptor Protein MITA
- (2009) Bo Zhong et al. IMMUNITY
- A host type I interferon response is induced by cytosolic sensing of the bacterial second messenger cyclic-di-GMP
- (2009) Sarah M. McWhirter et al. JOURNAL OF EXPERIMENTAL MEDICINE
- STING regulates intracellular DNA-mediated, type I interferon-dependent innate immunity
- (2009) Hiroki Ishikawa et al. NATURE
- Atg9a controls dsDNA-driven dynamic translocation of STING and the innate immune response
- (2009) T. Saitoh et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- ERIS, an endoplasmic reticulum IFN stimulator, activates innate immune signaling through dimerization
- (2009) W. Sun et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- RIG-I-like receptors: Sensing and responding to RNA virus infection
- (2009) Peyman Nakhaei et al. SEMINARS IN IMMUNOLOGY
- Trex1 Prevents Cell-Intrinsic Initiation of Autoimmunity
- (2008) Daniel B. Stetson et al. CELL
- The Adaptor Protein MITA Links Virus-Sensing Receptors to IRF3 Transcription Factor Activation
- (2008) Bo Zhong et al. IMMUNITY
- STING is an endoplasmic reticulum adaptor that facilitates innate immune signalling
- (2008) Hiroki Ishikawa et al. NATURE
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