Integrated proteomics and network analysis identifies protein hubs and network alterations in Alzheimer’s disease
出版年份 2018 全文链接
标题
Integrated proteomics and network analysis identifies protein hubs and network alterations in Alzheimer’s disease
作者
关键词
Alzheimer’s disease, Brain proteome, Mass spectrometry, Quantitative proteomics, Differential expression analysis, Protein co-expression network analysis, Neurodegeneration, Network biology
出版物
Acta Neuropathologica Communications
Volume 6, Issue 1, Pages -
出版商
Springer Nature
发表日期
2018-03-01
DOI
10.1186/s40478-018-0524-2
参考文献
相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。- The Obesity Related Gene, FTO, Interacts with APOE, and is Associated with Alzheimer's Disease Risk: A Prospective Cohort Study
- (2018) Lina Keller et al. JOURNAL OF ALZHEIMERS DISEASE
- Candidate Blood Proteome Markers of Alzheimer's Disease Onset and Progression: A Systematic Review and Replication Study
- (2018) Steven J. Kiddle et al. JOURNAL OF ALZHEIMERS DISEASE
- Quantitative proteomics identifies altered O-GlcNAcylation of structural, synaptic and memory-associated proteins in Alzheimer's disease
- (2017) Sheng Wang et al. JOURNAL OF PATHOLOGY
- A systems level analysis of epileptogenesis-associated proteome alterations
- (2017) Michael Keck et al. NEUROBIOLOGY OF DISEASE
- Synaptic Impairment in Alzheimer’s Disease: A Dysregulated Symphony
- (2017) Stefania Forner et al. TRENDS IN NEUROSCIENCES
- Genome-wide, high-content siRNA screening identifies the Alzheimer’s genetic risk factor FERMT2 as a major modulator of APP metabolism
- (2016) Julien Chapuis et al. ACTA NEUROPATHOLOGICA
- Disorders of lysosomal acidification—The emerging role of v-ATPase in aging and neurodegenerative disease
- (2016) Daniel J. Colacurcio et al. AGEING RESEARCH REVIEWS
- Neuroinflammation in Alzheimer's disease: Current evidence and future directions
- (2016) Valeria Calsolaro et al. Alzheimers & Dementia
- Clusterin levels are increased in Alzheimer's disease and influence the regional distribution of Aβ
- (2016) J. Scott Miners et al. BRAIN PATHOLOGY
- Actin dynamics and cofilin-actin rods in alzheimer disease
- (2016) James R. Bamburg et al. Cytoskeleton
- Alzheimer’s Disease Risk Genes and Lipid Regulators
- (2016) Farida El Gaamouch et al. JOURNAL OF ALZHEIMERS DISEASE
- The amyloid cascade hypothesis: are we poised for success or failure?
- (2016) Eric Karran et al. JOURNAL OF NEUROCHEMISTRY
- Walking the tightrope: proteostasis and neurodegenerative disease
- (2016) Justin J. Yerbury et al. JOURNAL OF NEUROCHEMISTRY
- Identification of proteins that are differentially expressed in brains with Alzheimer's disease using iTRAQ labeling and tandem mass spectrometry
- (2016) Benito Minjarez et al. Journal of Proteomics
- Alzheimer's disease
- (2016) Philip Scheltens et al. LANCET
- Genetic variations underlying Alzheimer's disease: evidence from genome-wide association studies and beyond
- (2016) Elise Cuyvers et al. LANCET NEUROLOGY
- Heatmapper: web-enabled heat mapping for all
- (2016) Sasha Babicki et al. NUCLEIC ACIDS RESEARCH
- Loss of Bin1 Promotes the Propagation of Tau Pathology
- (2016) Sara Calafate et al. Cell Reports
- RNAseq Analyses Identify Tumor Necrosis Factor-Mediated Inflammation as a Major Abnormality in ALS Spinal Cord
- (2016) David G. Brohawn et al. PLoS One
- The Biology of Proteostasis in Aging and Disease
- (2015) Johnathan Labbadia et al. Annual Review of Biochemistry
- Learning by Failing: Ideas and Concepts to Tackle γ-Secretases in Alzheimer's Disease and Beyond
- (2015) Bart De Strooper et al. Annual Review of Pharmacology and Toxicology
- Alzheimer’s Disease: Lessons Learned from Amyloidocentric Clinical Trials
- (2015) Andreas Soejitno et al. CNS DRUGS
- The Ezrin-Radixin-Moesin Family of Proteins in the Regulation of B-Cell Immune Response
- (2015) Debasis Pore et al. CRITICAL REVIEWS IN IMMUNOLOGY
- Neurodegeneration and Alzheimer's disease (AD). What Can Proteomics Tell Us About the Alzheimer's Brain?
- (2015) Guillermo Moya-Alvarado et al. MOLECULAR & CELLULAR PROTEOMICS
- Transcriptional networks implicated in human nonalcoholic fatty liver disease
- (2015) Hua Ye et al. MOLECULAR GENETICS AND GENOMICS
- Opposite Dysregulation of Fragile-X Mental Retardation Protein and Heteronuclear Ribonucleoprotein C Protein Associates with Enhanced APP Translation in Alzheimer Disease
- (2015) Antonella Borreca et al. MOLECULAR NEUROBIOLOGY
- The Ubiquitin-Proteasome System and Molecular Chaperone Deregulation in Alzheimer’s Disease
- (2015) Yanuar Alan Sulistio et al. MOLECULAR NEUROBIOLOGY
- Neutrophils promote Alzheimer's disease–like pathology and cognitive decline via LFA-1 integrin
- (2015) Elena Zenaro et al. NATURE MEDICINE
- Retromer in Alzheimer disease, Parkinson disease and other neurological disorders
- (2015) Scott A. Small et al. NATURE REVIEWS NEUROSCIENCE
- Early changes in extracellular matrix in Alzheimer's disease
- (2015) F.-X. Lepelletier et al. NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY
- Network-based proteomic analysis for postmenopausal osteoporosis in Caucasian females
- (2015) Lan Zhang et al. PROTEOMICS
- Is label-free LC-MS/MS ready for biomarker discovery?
- (2015) Marianne Sandin et al. Proteomics Clinical Applications
- Neurodegeneration and microtubule dynamics: death by a thousand cuts
- (2015) Jyoti Dubey et al. Frontiers in Cellular Neuroscience
- Mutation of senataxin alters disease-specific transcriptional networks in patients with ataxia with oculomotor apraxia type 2
- (2014) Brent L. Fogel et al. HUMAN MOLECULAR GENETICS
- Multi-enzyme digestion FASP and the ‘Total Protein Approach’-based absolute quantification of the Escherichia coli proteome
- (2014) Jacek R. Wiśniewski et al. Journal of Proteomics
- Versatility of the complement system in neuroinflammation, neurodegeneration and brain homeostasis
- (2014) Franca Orsini et al. Frontiers in Cellular Neuroscience
- Co-expression network analysis identifies Spleen Tyrosine Kinase (SYK) as a candidate oncogenic driver in a subset of small-cell lung cancer
- (2013) Akshata R Udyavar et al. BMC Systems Biology
- Serine racemase: a key player in neuron activity and in neuropathologies
- (2013) Andrea Mozzarelli Frontiers in Bioscience-Landmark
- Motor and sensory neuropathy due to myelin infolding and paranodal damage in a transgenic mouse model of Charcot–Marie–Tooth disease type 1C
- (2013) Samuel M. Lee et al. HUMAN MOLECULAR GENETICS
- Functional screening in Drosophila identifies Alzheimer's disease susceptibility genes and implicates Tau-mediated mechanisms
- (2013) J. M. Shulman et al. HUMAN MOLECULAR GENETICS
- Recent advances in quantitative neuroproteomics
- (2013) George E. Craft et al. METHODS
- The bigger picture of FTO—the first GWAS-identified obesity gene
- (2013) Ruth J. F. Loos et al. Nature Reviews Endocrinology
- When Is Hub Gene Selection Better than Standard Meta-Analysis?
- (2013) Peter Langfelder et al. PLoS One
- Genetic Association Study betweenSTK39 and CCDC62/HIP1R and Parkinson’s Disease
- (2013) Nan-Nan Li et al. PLoS One
- Na+ and K+ ion imbalances in Alzheimer's disease
- (2012) Victor M. Vitvitsky et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- Normalization and missing value imputation for label-free LC-MS analysis
- (2012) Yuliya V Karpievitch et al. BMC BIOINFORMATICS
- Label-Free Quantitative LC–MS Proteomics of Alzheimer’s Disease and Normally Aged Human Brains
- (2012) Victor P. Andreev et al. JOURNAL OF PROTEOME RESEARCH
- Network Organization of the Huntingtin Proteomic Interactome in Mammalian Brain
- (2012) Dyna I. Shirasaki et al. NEURON
- Central roles of apoptotic proteins in mitochondrial function
- (2012) S M Kilbride et al. ONCOGENE
- Genetic Variants in the Fat and Obesity Associated (FTO) Gene and Risk of Alzheimer's Disease
- (2012) Christiane Reitz et al. PLoS One
- National Institute on Aging–Alzheimer’s Association guidelines for the neuropathologic assessment of Alzheimer’s disease: a practical approach
- (2011) Thomas J. Montine et al. ACTA NEUROPATHOLOGICA
- The diagnosis of dementia due to Alzheimer’s disease: Recommendations from the National Institute on Aging-Alzheimer’s Association workgroups on diagnostic guidelines for Alzheimer's disease
- (2011) Guy M. McKhann et al. Alzheimers & Dementia
- Transcriptomic analysis of autistic brain reveals convergent molecular pathology
- (2011) Irina Voineagu et al. NATURE
- ARF family G proteins and their regulators: roles in membrane transport, development and disease
- (2011) Julie G. Donaldson et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Association of ApoE and LRP mRNA levels with dementia and AD neuropathology
- (2011) Afia Akram et al. NEUROBIOLOGY OF AGING
- Role of Rab GTPases in Membrane Traffic and Cell Physiology
- (2011) Alex H. Hutagalung et al. PHYSIOLOGICAL REVIEWS
- An update on clinical proteomics in Alzheimer’s research
- (2009) Minna A. Korolainen et al. JOURNAL OF NEUROCHEMISTRY
- Universal sample preparation method for proteome analysis
- (2009) Jacek R Wiśniewski et al. NATURE METHODS
- Rab GTPases as coordinators of vesicle traffic
- (2009) Harald Stenmark NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Alzheimer's disease as homeostatic responses to age-related myelin breakdown
- (2009) George Bartzokis NEUROBIOLOGY OF AGING
- An analysis of candidate autism loci on chromosome 2q24-q33: Evidence for association to theSTK39gene
- (2008) Nicolas Ramoz et al. AMERICAN JOURNAL OF MEDICAL GENETICS PART B-NEUROPSYCHIATRIC GENETICS
- WGCNA: an R package for weighted correlation network analysis
- (2008) Peter Langfelder et al. BMC BIOINFORMATICS
- A Systems Level Analysis of Transcriptional Changes in Alzheimer's Disease and Normal Aging
- (2008) J. A. Miller et al. JOURNAL OF NEUROSCIENCE
- Functional organization of the transcriptome in human brain
- (2008) Michael C Oldham et al. NATURE NEUROSCIENCE
- Whole-genome association study identifies STK39 as a hypertension susceptibility gene
- (2008) Y. Wang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Geometric Interpretation of Gene Coexpression Network Analysis
- (2008) Steve Horvath et al. PLoS Computational Biology
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