标题
Retromer in Alzheimer disease, Parkinson disease and other neurological disorders
作者
关键词
-
出版物
NATURE REVIEWS NEUROSCIENCE
Volume 16, Issue 3, Pages 126-132
出版商
Springer Nature
发表日期
2015-02-11
DOI
10.1038/nrn3896
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Parkinson’s Disease Genes VPS35 and EIF4G1 Interact Genetically and Converge on α-Synuclein
- (2015) Nripesh Dhungel et al. NEURON
- Apolipoprotein E in Alzheimer's Disease: An Update
- (2014) Jin-Tai Yu et al. Annual Review of Neuroscience
- Microglial dysfunction in brain aging and Alzheimer's disease
- (2014) Kira Irving Mosher et al. BIOCHEMICAL PHARMACOLOGY
- Retromer Binding to FAM21 and the WASH Complex Is Perturbed by the Parkinson Disease-Linked VPS35(D620N) Mutation
- (2014) Ian J. McGough et al. CURRENT BIOLOGY
- Novel ethyl methanesulfonate (EMS)-induced null alleles of the Drosophila homolog of LRRK2 reveal a crucial role in endolysosomal functions and autophagy in vivo
- (2014) M. W. Dodson et al. Disease Models & Mechanisms
- Parkinson's disease-linked mutations in VPS35 induce dopaminergic neurodegeneration
- (2014) E. Tsika et al. HUMAN MOLECULAR GENETICS
- Extracellular Monomeric Tau Protein Is Sufficient to Initiate the Spread of Tau Protein Pathology
- (2014) Claire H. Michel et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Rapid Mapping of Interactions between Human SNX-BAR Proteins MeasuredIn Vitroby AlphaScreen and Single-molecule Spectroscopy
- (2014) Emma Sierecki et al. MOLECULAR & CELLULAR PROTEOMICS
- Vacuolar protein sorting 35 (Vps35) rescues locomotor deficits and shortened lifespan in Drosophila expressing a Parkinson’s disease mutant of Leucine-rich repeat kinase 2 (LRRK2)
- (2014) Radek Linhart et al. Molecular Neurodegeneration
- Pharmacological chaperones stabilize retromer to limit APP processing
- (2014) Vincent J Mecozzi et al. Nature Chemical Biology
- Large-scale meta-analysis of genome-wide association data identifies six new risk loci for Parkinson's disease
- (2014) Mike A Nalls et al. NATURE GENETICS
- VPS35 dysfunction impairs lysosomal degradation of α-synuclein and exacerbates neurotoxicity in a Drosophila model of Parkinson's disease
- (2014) Emiko Miura et al. NEUROBIOLOGY OF DISEASE
- Isolating Pathogenic Mechanisms Embedded within the Hippocampal Circuit through Regional Vulnerability
- (2014) Scott A. Small NEURON
- Retromer Mediates a Discrete Route of Local Membrane Delivery to Dendrites
- (2014) Regina Wai-Yan Choy et al. NEURON
- Pharmacological chaperones in the age of proteomic pathology
- (2014) S. A. Small PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- A unique PDZ domain and arrestin-like fold interaction reveals mechanistic details of endocytic recycling by SNX27-retromer
- (2014) M. Gallon et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Sorting Nexin 27 regulates basal and activity-dependent trafficking of AMPARs
- (2014) N. K. Hussain et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Potential Alzheimer's Drug Spurs Protein Recycling
- (2014) K. Garber SCIENCE
- TREM2 mutations implicated in neurodegeneration impair cell surface transport and phagocytosis
- (2014) G. Kleinberger et al. Science Translational Medicine
- Retromer: A Master Conductor of Endosome Sorting
- (2014) C. Burd et al. Cold Spring Harbor Perspectives in Biology
- Mutation in VPS35 associated with Parkinson’s disease impairs WASH complex association and inhibits autophagy
- (2014) Eszter Zavodszky et al. Nature Communications
- A role for sorting nexin 27 in AMPA receptor trafficking
- (2014) Li Shen Loo et al. Nature Communications
- Pathogenic Mutation in VPS35 Impairs Its Protection against MPP+ Cytotoxicity
- (2013) Fangfang Bi et al. International Journal of Biological Sciences
- A global analysis of SNX27–retromer assembly and cargo specificity reveals a function in glucose and metal ion transport
- (2013) Florian Steinberg et al. NATURE CELL BIOLOGY
- Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease
- (2013) Jean-Charles Lambert et al. NATURE GENETICS
- Noncanonical EF-hand motif strategically delays Ca2+ buffering to enhance cardiac performance
- (2013) Wang Wang et al. NATURE MEDICINE
- The role of autophagy in neurodegenerative disease
- (2013) Ralph A Nixon NATURE MEDICINE
- Molecular drivers and cortical spread of lateral entorhinal cortex dysfunction in preclinical Alzheimer's disease
- (2013) Usman A Khan et al. NATURE NEUROSCIENCE
- RAB7L1 Interacts with LRRK2 to Modify Intraneuronal Protein Sorting and Parkinson’s Disease Risk
- (2013) David A. MacLeod et al. NEURON
- Microglial Beclin 1 Regulates Retromer Trafficking and Phagocytosis and Is Impaired in Alzheimer’s Disease
- (2013) Kurt M. Lucin et al. NEURON
- A mechanism for retromer endosomal coat complex assembly with cargo
- (2013) M. S. Harrison et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The Vps35 D620N Mutation Linked to Parkinson's Disease Disrupts the Cargo Sorting Function of Retromer
- (2013) Jordan Follett et al. TRAFFIC
- Phosphatidylinositol-3-phosphate regulates sorting and processing of amyloid precursor protein through the endosomal system
- (2013) Etienne Morel et al. Nature Communications
- Independent and epistatic effects of variants in VPS10-d receptors on Alzheimer disease risk and processing of the amyloid precursor protein (APP)
- (2013) C Reitz et al. Translational Psychiatry
- Molecular basis for SNX-BAR-mediated assembly of distinct endosomal sorting tubules
- (2012) Jan R T van Weering et al. EMBO JOURNAL
- Small Misfolded Tau Species Are Internalized via Bulk Endocytosis and Anterogradely and Retrogradely Transported in Neurons
- (2012) Jessica W. Wu et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- RAB-6.2 and the retromer regulate glutamate receptor recycling through a retrograde pathway
- (2012) Donglei Zhang et al. JOURNAL OF CELL BIOLOGY
- Retromer Binds the FANSHY Sorting Motif in SorLA to Regulate Amyloid Precursor Protein Sorting and Processing
- (2012) A. W. Fjorback et al. JOURNAL OF NEUROSCIENCE
- Vps10 Family Proteins and the Retromer Complex in Aging-Related Neurodegeneration and Diabetes
- (2012) R. F. Lane et al. JOURNAL OF NEUROSCIENCE
- The Role of Ceroid Lipofuscinosis Neuronal Protein 5 (CLN5) in Endosomal Sorting
- (2012) A. Mamo et al. MOLECULAR AND CELLULAR BIOLOGY
- Identification of Alzheimer disease-associated variants in genes that regulate retromer function
- (2012) Badri N. Vardarajan et al. NEUROBIOLOGY OF AGING
- The location and trafficking routes of the neuronal retromer and its role in amyloid precursor protein transport
- (2012) Akhil Bhalla et al. NEUROBIOLOGY OF DISEASE
- TREM2 Variants in Alzheimer's Disease
- (2012) Rita Guerreiro et al. NEW ENGLAND JOURNAL OF MEDICINE
- Amyloid precursor protein (APP) traffics from the cell surface via endosomes for amyloid β (Aβ) production in thetrans-Golgi network
- (2012) Regina Wai-Yan Choy et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Pathological -Synuclein Transmission Initiates Parkinson-like Neurodegeneration in Nontransgenic Mice
- (2012) K. C. Luk et al. SCIENCE
- Mechanisms of Protein Seeding in Neurodegenerative Diseases
- (2012) Lary C. Walker et al. JAMA Neurology
- A Mutation in VPS35, Encoding a Subunit of the Retromer Complex, Causes Late-Onset Parkinson Disease
- (2011) Alexander Zimprich et al. AMERICAN JOURNAL OF HUMAN GENETICS
- VPS35 Mutations in Parkinson Disease
- (2011) Carles Vilariño-Güell et al. AMERICAN JOURNAL OF HUMAN GENETICS
- The ESCRT Pathway
- (2011) William M. Henne et al. DEVELOPMENTAL CELL
- VPS35 haploinsufficiency increases Alzheimer’s disease neuropathology
- (2011) Lei Wen et al. JOURNAL OF CELL BIOLOGY
- A SNX3-dependent retromer pathway mediates retrograde transport of the Wnt sorting receptor Wntless and is required for Wnt secretion
- (2011) Martin Harterink et al. NATURE CELL BIOLOGY
- SNX27 mediates retromer tubule entry and endosome-to-plasma membrane trafficking of signalling receptors
- (2011) Paul Temkin et al. NATURE CELL BIOLOGY
- Retromer terminates the generation of cAMP by internalized PTH receptors
- (2011) Timothy N Feinstein et al. Nature Chemical Biology
- Erratum: Hereditary spastic paraplegias: membrane traffic and the motor pathway
- (2011) Craig Blackstone et al. NATURE REVIEWS NEUROSCIENCE
- Vps26A and Vps26B Subunits Define Distinct Retromer Complexes
- (2011) Andrea Bugarcic et al. TRAFFIC
- Implication of mouse Vps26b–Vps29–Vps35 retromer complex in sortilin trafficking
- (2010) Ekyune Kim et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- The cargo-selective retromer complex is a recruiting hub for protein complexes that regulate endosomal tubule dynamics
- (2010) M. E. Harbour et al. JOURNAL OF CELL SCIENCE
- Diabetes-Associated SorCS1 Regulates Alzheimer's Amyloid- Metabolism: Evidence for Involvement of SorL1 and the Retromer Complex
- (2010) R. F. Lane et al. JOURNAL OF NEUROSCIENCE
- Charting the Secretory Pathway in a Simple Eukaryote
- (2010) Randy Schekman MOLECULAR BIOLOGY OF THE CELL
- Retrieval of the Alzheimer's amyloid precursor protein from the endosome to the TGN is S655 phosphorylation state-dependent and retromer-mediated
- (2010) Sandra I Vieira et al. Molecular Neurodegeneration
- Lysosomal Dysfunction Promotes Cleavage and Neurotoxicity of Tau In Vivo
- (2010) Vikram Khurana et al. PLoS Genetics
- A FAM21-Containing WASH Complex Regulates Retromer-Dependent Sorting
- (2009) Timothy S. Gomez et al. DEVELOPMENTAL CELL
- Membrane recruitment of the cargo-selective retromer subcomplex is catalysed by the small GTPase Rab7 and inhibited by the Rab-GAP TBC1D5
- (2009) M. N. J. Seaman et al. JOURNAL OF CELL SCIENCE
- Identification of novel retromer complexes in the mouse testis
- (2008) Ekyune Kim et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Sortilin mediates the lysosomal targeting of cathepsins D and H
- (2008) Maryssa Canuel et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Neuronal ceroid lipofuscinoses
- (2008) Anu Jalanko et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
- Regulation of retromer recruitment to endosomes by sequential action of Rab5 and Rab7
- (2008) Raul Rojas et al. JOURNAL OF CELL BIOLOGY
- Retromer deficiency observed in Alzheimer's disease causes hippocampal dysfunction, neurodegeneration, and A accumulation
- (2008) A. Muhammad et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Structure of Vps26B and Mapping of its Interaction with the Retromer Protein Complex
- (2008) Brett M. Collins et al. TRAFFIC
- Loss of the Batten Disease Gene CLN3 Prevents Exit from the TGN of the Mannose 6-Phosphate Receptor
- (2008) Daniel J Metcalf et al. TRAFFIC
Publish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn MoreFind the ideal target journal for your manuscript
Explore over 38,000 international journals covering a vast array of academic fields.
Search