Abolition of mitochondrial substrate-level phosphorylation by itaconic acid produced by LPS-induced Irg1 expression in cells of murine macrophage lineage

Itaconic Acid: The Surprising Role of an Industrial Compound as a Mammalian Antimicrobial Metabolite

(2015) Thekla Cordes et al.   Annual Review of Nutrition

The contributions of respiration and glycolysis to extracellular acid production

(2015) Shona A. Mookerjee et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Hypoxia and hypoxia inducible factors in tumor metabolism

(2015) Wen Zeng et al.   CANCER LETTERS

Coenzyme A and its derivatives: renaissance of a textbook classic

(2014) Frederica L. Theodoulou et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Mitochondrial diaphorases as NAD+ donors to segments of the citric acid cycle that support substrate-level phosphorylation yielding ATP during respiratory inhibition

(2014) Gergely Kiss et al.   FASEB JOURNAL

Cellular Metabolism and Macrophage Functional Polarization

(2014) Linnan Zhu et al.   INTERNATIONAL REVIEWS OF IMMUNOLOGY

Novel Characteristics of Succinate Coenzyme A (Succinate-CoA) Ligases: Conversion of Malate to Malyl-CoA and CoA-Thioester Formation of Succinate AnaloguesIn Vitro

(2013) Johannes Christoph Nolte et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

The negative impact of α-ketoglutarate dehydrogenase complex deficiency on matrix substrate-level phosphorylation

(2013) Gergely Kiss et al.   FASEB JOURNAL

Bioenergetic Profiles Diverge During Macrophage Polarization: Implications for the Interpretation of 18F-FDG PET Imaging of Atherosclerosis

(2013) S. Tavakoli et al.   JOURNAL OF NUCLEAR MEDICINE

Succinate is an inflammatory signal that induces IL-1β through HIF-1α

(2013) G. M. Tannahill et al.   NATURE

Immune-responsive gene 1 protein links metabolism to immunity by catalyzing itaconic acid production

(2013) A. Michelucci et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Succinate: a metabolic signal in inflammation

(2013) Evanna Mills et al.   TRENDS IN CELL BIOLOGY

Biochemistry of microbial itaconic acid production

(2013) Matthias G. Steiger et al.   Frontiers in Microbiology

25-Hydroxycholesterol-3-sulfate attenuates inflammatory response via PPARγ signaling in human THP-1 macrophages

(2012) Leyuan Xu et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Commitment to glycolysis sustains survival of NO-producing inflammatory dendritic cells

(2012) B. Everts et al.   BLOOD

Hypoxia-mediated regulation of macrophage functions in pathophysiology

(2012) Elena Riboldi et al.   INTERNATIONAL IMMUNOLOGY

Naringin inhibits chemokine production in an LPS-induced RAW 264.7 macrophage cell line

(2012) YING LIU et al.   Molecular Medicine Reports

Highly Sensitive GC/MS/MS Method for Quantitation of Amino and Nonamino Organic Acids

(2011) Hans F. N. Kvitvang et al.   ANALYTICAL CHEMISTRY

Mitochondrial consumption of cytosolic ATP: Not so fast

(2011) Christos Chinopoulos   FEBS LETTERS

Relevance of the MEK/ERK Signaling Pathway in the Metabolism of Activated Macrophages: A Metabolomic Approach

(2011) P. G. Traves et al.   JOURNAL OF IMMUNOLOGY

The “B Space” of mitochondrial phosphorylation

(2011) Christos Chinopoulos   JOURNAL OF NEUROSCIENCE RESEARCH

1H NMR-based Metabolomic Profiling in Mice Infected withMycobacterium tuberculosis

(2011) Ji-Hyun Shin et al.   JOURNAL OF PROTEOME RESEARCH

Itaconic Acid Is a Mammalian Metabolite Induced during Macrophage Activation

(2011) Cheryl L. Strelko et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Non-targeted metabolite profiling in activated macrophage secretion

(2011) Masahiro Sugimoto et al.   Metabolomics

Expression profile of human immune-responsive gene 1 and generation and characterization of polyclonal antiserum

(2011) Wei Xiao et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Toll-like receptor-induced changes in glycolytic metabolism regulate dendritic cell activation

(2010) C. M. Krawczyk et al.   BLOOD

Activated macrophages utilize glycolytic ATP to maintain mitochondrial membrane potential and prevent apoptotic cell death

(2010) A Garedew et al.   CELL DEATH AND DIFFERENTIATION

Forward operation of adenine nucleotide translocase during F0F1-ATPase reversal: critical role of matrix substrate-level phosphorylation

(2010) Christos Chinopoulos et al.   FASEB JOURNAL

Substrate Fate in Activated Macrophages: A Comparison between Innate, Classic, and Alternative Activation

(2010) J.-C. Rodriguez-Prados et al.   JOURNAL OF IMMUNOLOGY

Metabolomic Patterns in Glioblastoma and Changes during Radiotherapy: A Clinical Microdialysis Study

(2010) Carl Wibom et al.   JOURNAL OF PROTEOME RESEARCH

Quantitative Microplate-Based Respirometry with Correction for Oxygen Diffusion

(2009) Akos A. Gerencser et al.   ANALYTICAL CHEMISTRY

Biotechnological production of itaconic acid and its biosynthesis in Aspergillus terreus

(2009) Mitsuyasu Okabe et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

A Novel Kinetic Assay of Mitochondrial ATP-ADP Exchange Rate Mediated by the ANT

(2009) Christos Chinopoulos et al.   BIOPHYSICAL JOURNAL

Aryl hydrocarbon receptor in combination with Stat1 regulates LPS-induced inflammatory responses

(2009) Akihiro Kimura et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Understanding the Warburg Effect: The Metabolic Requirements of Cell Proliferation

(2009) M. G. Vander Heiden et al.   SCIENCE

Mechanisms underlying the loss of mitochondrial membrane potential in glutamate excitotoxicity

(2008) Andrey Y. Abramov et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

The ADP and ATP transport in mitochondria and its carrier

(2008) Martin Klingenberg   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

The Proinflammatory Cytokine-Induced IRG1 Protein Associates with Mitochondria

(2008) Daniel Degrandi et al.   JOURNAL OF INTERFERON AND CYTOKINE RESEARCH