Suppression of luteinizing hormone enhances HSC recovery after hematopoietic injury

Transient CDK4/6 inhibition protects hematopoietic stem cells from chemotherapy-induced exhaustion

(2017) Shenghui He et al.   Science Translational Medicine

Angiogenin Promotes Hematopoietic Regeneration by Dichotomously Regulating Quiescence of Stem and Progenitor Cells

(2016) Kevin A. Goncalves et al.   CELL

The frequency of multipotent CD133+CD45RA−CD34+ hematopoietic stem cells is not increased in fetal liver compared with adult stem cell sources

(2016) Stefan Radtke et al.   EXPERIMENTAL HEMATOLOGY

Hematopoietic Stem/Progenitor Cells Express Several Functional Sex Hormone Receptors—Novel Evidence for a Potential Developmental Link Between Hematopoiesis and Primordial Germ Cells

(2015) Katarzyna Mierzejewska et al.   STEM CELLS AND DEVELOPMENT

Enhanced Hematopoietic Stem Cell Function Mediates Immune Regeneration following Sex Steroid Blockade

(2015) Danika M. Khong et al.   Stem Cell Reports

Total body irradiation causes long-term mouse BM injury via induction of HSC premature senescence in an Ink4a- and Arf-independent manner

(2014) L. Shao et al.   BLOOD

Bcl2 overexpression rescues the hematopoietic stem cell defects in Ku70-deficient mice by restoration of quiescence

(2014) Y. Qing et al.   BLOOD

Estrogen Signaling Selectively Induces Apoptosis of Hematopoietic Progenitors and Myeloid Neoplasms without Harming Steady-State Hematopoiesis

(2014) Abel Sánchez-Aguilera et al.   Cell Stem Cell

Pleiotrophin mediates hematopoietic regeneration via activation of RAS

(2014) Heather A. Himburg et al.   JOURNAL OF CLINICAL INVESTIGATION

Sex steroid blockade enhances thymopoiesis by modulating Notch signaling

(2014) Enrico Velardi et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Oestrogen increases haematopoietic stem-cell self-renewal in females and during pregnancy

(2014) Daisuke Nakada et al.   NATURE

Precocious Puberty and Leydig Cell Hyperplasia in Male Mice With a Gain of Function Mutation in the LH Receptor Gene

(2013) Stacey R. McGee et al.   ENDOCRINOLOGY

TGFβ restores hematopoietic homeostasis after myelosuppressive chemotherapy

(2013) Fabienne Brenet et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Luteinizing hormone and human chorionic gonadotropin: Origins of difference

(2013) Janet Choi et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Nrf2 regulates haematopoietic stem cell function

(2013) Jennifer J. Tsai et al.   NATURE CELL BIOLOGY

Epidermal growth factor regulates hematopoietic regeneration after radiation injury

(2013) Phuong L Doan et al.   NATURE MEDICINE

Radiation damage and radioprotectants: new concepts in the era of molecular medicine

(2012) M I Koukourakis   BRITISH JOURNAL OF RADIOLOGY

Vascular niche E-selectin regulates hematopoietic stem cell dormancy, self renewal and chemoresistance

(2012) Ingrid G Winkler et al.   NATURE MEDICINE

Fine-tuning p53 activity through C-terminal modification significantly contributes to HSC homeostasis and mouse radiosensitivity

(2011) Y. V. Wang et al.   GENES & DEVELOPMENT

Isolation of Single Human Hematopoietic Stem Cells Capable of Long-Term Multilineage Engraftment

(2011) F. Notta et al.   SCIENCE

Mitigation of hematologic radiation toxicity in mice through pharmacological quiescence induced by CDK4/6 inhibition

(2010) Søren M. Johnson et al.   JOURNAL OF CLINICAL INVESTIGATION

Sex Steroid Ablation Enhances Immune Reconstitution Following Cytotoxic Antineoplastic Therapy in Young Mice

(2010) G. L. Goldberg et al.   JOURNAL OF IMMUNOLOGY

Animal Models for Medical Countermeasures to Radiation Exposure

(2010) Jacqueline P. Williams et al.   RADIATION RESEARCH

Constitutively active AKT depletes hematopoietic stem cells and induces leukemia in mice

(2009) M. G. Kharas et al.   BLOOD

Sex Steroid Ablation Enhances Hematopoietic Recovery following Cytotoxic Antineoplastic Therapy in Aged Mice

(2009) J. A. Dudakov et al.   JOURNAL OF IMMUNOLOGY

Withdrawal of Sex Steroids Reverses Age- and Chemotherapy-Related Defects in Bone Marrow Lymphopoiesis

(2009) Jarrod A. Dudakov et al.   JOURNAL OF IMMUNOLOGY

IFNα activates dormant haematopoietic stem cells in vivo

(2009) Marieke A. G. Essers et al.   NATURE

Male gonadal toxicity

(2009) Marvin L. Meistrich   PEDIATRIC BLOOD & CANCER

TSC–mTOR maintains quiescence and function of hematopoietic stem cells by repressing mitochondrial biogenesis and reactive oxygen species

(2008) Chong Chen et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Analysis of histone 2B-GFP retention reveals slowly cycling hematopoietic stem cells

(2008) Adlen Foudi et al.   NATURE BIOTECHNOLOGY