In Vivo Transient and Partial Cell Reprogramming to Pluripotency as a Therapeutic Tool for Neurodegenerative Diseases

The senescence-associated secretory phenotype induces cellular plasticity and tissue regeneration

(2017) Birgit Ritschka et al.   GENES & DEVELOPMENT

Advances in Decoding Axolotl Limb Regeneration

(2017) Brian J. Haas et al.   TRENDS IN GENETICS

Cocktail of chemical compounds robustly promoting cell reprogramming protects liver against acute injury

(2017) Yuewen Tang et al.   Protein & Cell

Common Telomere Changes during In Vivo Reprogramming and Early Stages of Tumorigenesis

(2017) Rosa M. Marión et al.   Stem Cell Reports

In Vivo Amelioration of Age-Associated Hallmarks by Partial Reprogramming

(2016) Alejandro Ocampo et al.   CELL

Bmi1 Is a Key Epigenetic Barrier to Direct Cardiac Reprogramming

(2016) Yang Zhou et al.   Cell Stem Cell

Naturally occurring p16Ink4a-positive cells shorten healthy lifespan

(2016) Darren J. Baker et al.   NATURE

A predictive computational framework for direct reprogramming between human cell types

(2016) Owen J L Rackham et al.   NATURE GENETICS

Conversion of human fibroblasts into functional cardiomyocytes by small molecules

(2016) Nan Cao et al.   SCIENCE

Tissue damage and senescence provide critical signals for cellular reprogramming in vivo

(2016) Lluc Mosteiro et al.   SCIENCE

In vivo reprogramming reactive glia into iPSCs to produce new neurons in the cortex following traumatic brain injury

(2016) Xiang Gao et al.   Scientific Reports

Direct Conversion of Normal and Alzheimer’s Disease Human Fibroblasts into Neuronal Cells by Small Molecules

(2015) Wenxiang Hu et al.   Cell Stem Cell

Small Molecules Efficiently Reprogram Human Astroglial Cells into Functional Neurons

(2015) Lei Zhang et al.   Cell Stem Cell

Experimental Advances Towards Neural Regeneration from Induced Stem Cells to Direct In Vivo Reprogramming

(2015) Sara Dametti et al.   MOLECULAR NEUROBIOLOGY

Epigenetic regulation of ageing: linking environmental inputs to genomic stability

(2015) Bérénice A. Benayoun et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

A Systematic Approach to Identify Candidate Transcription Factors that Control Cell Identity

(2015) Ana C. D’Alessio et al.   Stem Cell Reports

In vivocell reprogramming to pluripotency: exploring a novel tool for cell replenishment and tissue regeneration

(2014) Irene de Lázaro et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

CellNet: Network Biology Applied to Stem Cell Engineering

(2014) Patrick Cahan et al.   CELL

Premature Termination of Reprogramming In Vivo Leads to Cancer Development through Altered Epigenetic Regulation

(2014) Kotaro Ohnishi et al.   CELL

Hierarchical Mechanisms for Direct Reprogramming of Fibroblasts to Neurons

(2013) Orly L. Wapinski et al.   CELL

Reprogramming in vivo produces teratomas and iPS cells with totipotency features

(2013) María Abad et al.   NATURE

Early role for IL-6 signalling during generation of induced pluripotent stem cells revealed by heterokaryon RNA-Seq

(2013) Jennifer J. Brady et al.   NATURE CELL BIOLOGY

In Vivo Cell Reprogramming towards Pluripotency by Virus-Free Overexpression of Defined Factors

(2013) Açelya Yilmazer et al.   PLoS One

Pluripotent Stem Cells Induced from Mouse Somatic Cells by Small-Molecule Compounds

(2013) P. Hou et al.   SCIENCE

Aging, Rejuvenation, and Epigenetic Reprogramming: Resetting the Aging Clock

(2012) Thomas A. Rando et al.   CELL

Direct Conversion of Fibroblasts into Stably Expandable Neural Stem Cells

(2012) Marc Thier et al.   Cell Stem Cell

Aging and reprogramming: a two-way street

(2012) Salah Mahmoudi et al.   CURRENT OPINION IN CELL BIOLOGY

Non-viral Expression of Mouse Oct4, Sox2, and Klf4 Transcription Factors Efficiently Reprograms Tadpole Muscle Fibersin Vivo

(2012) Céline Vivien et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Conversion of human fibroblasts to angioblast-like progenitor cells

(2012) Leo Kurian et al.   NATURE METHODS

Rejuvenating senescent and centenarian human cells by reprogramming through the pluripotent state

(2011) L. Lapasset et al.   GENES & DEVELOPMENT

Clearance of p16Ink4a-positive senescent cells delays ageing-associated disorders

(2011) Darren J. Baker et al.   NATURE

Splicing-Directed Therapy in a New Mouse Model of Human Accelerated Aging

(2011) F. G. Osorio et al.   Science Translational Medicine

Generation of iPSCs from mouse fibroblasts with a single gene, Oct4 and small molecules

(2010) Yanqin Li et al.   CELL RESEARCH