Experimental Advances Towards Neural Regeneration from Induced Stem Cells to Direct In Vivo Reprogramming

Necroptosis Drives Motor Neuron Death in Models of Both Sporadic and Familial ALS

(2014) Diane B. Re et al.   NEURON

In Vivo Direct Reprogramming of Reactive Glial Cells into Functional Neurons after Brain Injury and in an Alzheimer’s Disease Model

(2013) Ziyuan Guo et al.   Cell Stem Cell

Cellular therapy to target neuroinflammation in amyotrophic lateral sclerosis

(2013) Federica Rizzo et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Direct lineage reprogramming of post-mitotic callosal neurons into corticofugal neurons in vivo

(2013) Caroline Rouaux et al.   NATURE CELL BIOLOGY

In vivo reprogramming of astrocytes to neuroblasts in the adult brain

(2013) Wenze Niu et al.   NATURE CELL BIOLOGY

In vivo reprogramming of circuit connectivity in postmitotic neocortical neurons

(2013) Andres De la Rossa et al.   NATURE NEUROSCIENCE

Opportunities and challenges of pluripotent stem cell neurodegenerative disease models

(2013) Jackson Sandoe et al.   NATURE NEUROSCIENCE

Generation of induced neurons via direct conversion in vivo

(2013) O. Torper et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Environmental impact on direct neuronal reprogramming in vivo in the adult brain

(2013) Andrew Grande et al.   Nature Communications

Direct Reprogramming of Fibroblasts into Neural Stem Cells by Defined Factors

(2012) Dong Wook Han et al.   Cell Stem Cell

Direct Reprogramming of Mouse and Human Fibroblasts into Multipotent Neural Stem Cells with a Single Factor

(2012) Karen L. Ring et al.   Cell Stem Cell

Direct Conversion of Fibroblasts into Stably Expandable Neural Stem Cells

(2012) Marc Thier et al.   Cell Stem Cell

Direct reprogramming of human astrocytes into neural stem cells and neurons

(2012) Stefania Corti et al.   EXPERIMENTAL CELL RESEARCH

Direct conversion of mouse fibroblasts to self-renewing, tripotent neural precursor cells

(2012) E. Lujan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Glial Progenitor Cell-Based Treatment and Modeling of Neurological Disease

(2012) S. A. Goldman et al.   SCIENCE

Genetic Correction of Human Induced Pluripotent Stem Cells from Patients with Spinal Muscular Atrophy

(2012) S. Corti et al.   Science Translational Medicine

Astrocytes generated from patient induced pluripotent stem cells recapitulate features of Huntington’s disease patient cells

(2012) Tarja A Juopperi et al.   Molecular Brain

Human embryonic stem cell derived astrocytes mediate non-cell-autonomous neuroprotection through endogenous and drug-induced mechanisms

(2011) K Gupta et al.   CELL DEATH AND DIFFERENTIATION

Direct reprogramming of human fibroblasts into dopaminergic neuron-like cells

(2011) Xinjian Liu et al.   CELL RESEARCH

Conversion of Mouse and Human Fibroblasts into Functional Spinal Motor Neurons

(2011) Esther Y. Son et al.   Cell Stem Cell

Direct generation of functional dopaminergic neurons from mouse and human fibroblasts

(2011) Massimiliano Caiazzo et al.   NATURE

Astrocytes from familial and sporadic ALS patients are toxic to motor neurons

(2011) Amanda M Haidet-Phillips et al.   NATURE BIOTECHNOLOGY

Direct reprogramming of mouse fibroblasts to neural progenitors

(2011) J. Kim et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Direct conversion of human fibroblasts to dopaminergic neurons

(2011) U. Pfisterer et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Teratomas from pluripotent stem cells: A clinical hurdle

(2010) Chui-Yee Fong et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Directing Astroglia from the Cerebral Cortex into Subtype Specific Functional Neurons

(2010) Christophe Heinrich et al.   PLOS BIOLOGY

A Fresh Look at iPS Cells

(2009) Shinya Yamanaka   CELL

Variation in the safety of induced pluripotent stem cell lines

(2009) Kyoko Miura et al.   NATURE BIOTECHNOLOGY