Autophagy and mitophagy flux in young and aged skeletal muscle following chronic contractile activity

Exercise induces TFEB expression and activity in skeletal muscle in a PGC-1α-dependent manner

(2018) Avigail T. Erlich et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Effect of contractile activity on PGC-1α transcription in young and aged skeletal muscle

(2018) Heather N. Carter et al.   JOURNAL OF APPLIED PHYSIOLOGY

Mitochondria Initiate and Regulate Sarcopenia

(2017) Stephen E. Alway et al.   EXERCISE AND SPORT SCIENCES REVIEWS

Monitoring and Measuring Autophagy

(2017) Saori R. Yoshii et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Molecular mechanism of sarcopenia and cachexia: recent research advances

(2017) Kunihiro Sakuma et al.   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

Ampk phosphorylation of Ulk1 is required for targeting of mitochondria to lysosomes in exercise-induced mitophagy

(2017) Rhianna C. Laker et al.   Nature Communications

Effects of aerobic training on markers of autophagy in the elderly

(2016) Yubisay Mejías-Peña et al.   AGE

Age-related deficits in skeletal muscle recovery following disuse are associated with neuromuscular junction instability and ER stress, not impaired protein synthesis

(2016) Leslie M. Baehr et al.   Aging-US

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

(2016) Daniel J Klionsky et al.   Autophagy

Unravelling the mechanisms regulating muscle mitochondrial biogenesis

(2016) D. A. Hood et al.   BIOCHEMICAL JOURNAL

Mfn2 deficiency links age‐related sarcopenia and impaired autophagy to activation of an adaptive mitophagy pathway

(2016) David Sebastián et al.   EMBO JOURNAL

Phospho-ubiquitin: upending the PINK–Parkin–ubiquitin cascade

(2016) Noriyuki Matsuda   JOURNAL OF BIOCHEMISTRY

Transcriptional regulation of mammalian autophagy at a glance

(2016) Jens Füllgrabe et al.   JOURNAL OF CELL SCIENCE

Autophagy plays a role in skeletal muscle mitochondrial biogenesis in an endurance exercise-trained condition

(2016) Jeong-sun Ju et al.   Journal of Physiological Sciences

The ageing neuromuscular system and sarcopenia: a mitochondrial perspective

(2016) Karolina A. Rygiel et al.   JOURNAL OF PHYSIOLOGY-LONDON

Phosphorylation of OPTN by TBK1 enhances its binding to Ub chains and promotes selective autophagy of damaged mitochondria

(2016) Benjamin Richter et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The impact of ageing, physical activity, and pre-frailty on skeletal muscle phenotype, mitochondrial content, and intramyocellular lipids in men

(2016) Félix St-Jean-Pelletier et al.   Journal of Cachexia Sarcopenia and Muscle

Mitochondrial Quality Control and Muscle Mass Maintenance

(2016) Vanina Romanello et al.   Frontiers in Physiology

Molecular basis for an attenuated mitochondrial adaptive plasticity in aged skeletal muscle

(2016) Vladimir Ljubicic et al.   Aging-US

Role of PGC-1α during acute exercise-induced autophagy and mitophagy in skeletal muscle

(2015) Anna Vainshtein et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Temporal dynamics of PARK2/parkin and OPTN/optineurin recruitment during the mitophagy of damaged mitochondria

(2015) Yvette C Wong et al.   Autophagy

Exercise training increases anabolic and attenuates catabolic and apoptotic processes in aged skeletal muscle of male rats

(2015) Mohammad Mosaferi Ziaaldini et al.   EXPERIMENTAL GERONTOLOGY

Autophagy: a druggable process that is deregulated in aging and human disease

(2015) Guido Kroemer   JOURNAL OF CLINICAL INVESTIGATION

Effects of ageing on expression of the muscle-specific E3 ubiquitin ligases and Akt-dependent regulation of Foxo transcription factors in skeletal muscle

(2015) Akira Wagatsuma et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Mitochondria, Muscle Health, and Exercise with Advancing Age

(2015) Heather N. Carter et al.   PHYSIOLOGY

Mitochondrial morphology is altered in atrophied skeletal muscle of aged mice

(2015) Jean-Philippe Leduc-Gaudet et al.   Oncotarget

p62/SQSTM1 but not LC3 is accumulated in sarcopenic muscle of mice

(2015) Kunihiro Sakuma et al.   Journal of Cachexia Sarcopenia and Muscle

PGC-1α modulates denervation-induced mitophagy in skeletal muscle

(2015) Anna Vainshtein et al.   Skeletal Muscle

Autophagic Signaling and Proteolytic Enzyme Activity in Cardiac and Skeletal Muscle of Spontaneously Hypertensive Rats following Chronic Aerobic Exercise

(2015) Elliott M. McMillan et al.   PLoS One

Aging related changes in determinants of muscle force generating capacity: A comparison of muscle aging in men and male rodents

(2014) Sam B. Ballak et al.   AGEING RESEARCH REVIEWS

Ubiquitin is phosphorylated by PINK1 to activate parkin

(2014) Fumika Koyano et al.   NATURE

Autophagy Impairment in Muscle Induces Neuromuscular Junction Degeneration and Precocious Aging

(2014) Silvia Carnio et al.   Cell Reports

Mitochondrial Involvement and Impact in Aging Skeletal Muscle

(2014) Russell T. Hepple   Frontiers in Aging Neuroscience

Increased autophagy accelerates colchicine-induced muscle toxicity

(2013) James K Ching et al.   Autophagy

Autophagic flux and oxidative capacity of skeletal muscles during acute starvation

(2013) Mahroo Mofarrahi et al.   Autophagy

Autophagy is required for exercise training-induced skeletal muscle adaptation and improvement of physical performance

(2013) Vitor A. Lira et al.   FASEB JOURNAL

Increased sensitivity to mitochondrial permeability transition and myonuclear translocation of endonuclease G in atrophied muscle of physically active older humans

(2013) Gilles Gouspillou et al.   FASEB JOURNAL

p53 Mediates Autophagy and Cell Death by a Mechanism Contingent On Bnip3

(2013) Erika Yan Wang et al.   HYPERTENSION

Sirtuin 1-mediated Effects of Exercise and Resveratrol on Mitochondrial Biogenesis

(2013) Keir J. Menzies et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Acute exercise induces tumour suppressor protein p53 translocation to the mitochondria and promotes a p53-Tfam-mitochondrial DNA complex in skeletal muscle

(2013) Ayesha Saleem et al.   JOURNAL OF PHYSIOLOGY-LONDON

Expression of mitochondrial fission and fusion regulatory proteins in skeletal muscle during chronic use and disuse

(2013) Sobia Iqbal et al.   MUSCLE & NERVE

PINK1-Phosphorylated Mitofusin 2 Is a Parkin Receptor for Culling Damaged Mitochondria

(2013) Y. Chen et al.   SCIENCE

Beclin 1 interactome controls the crosstalk between apoptosis, autophagy and inflammasome activation: Impact on the aging process

(2012) Antero Salminen et al.   AGEING RESEARCH REVIEWS

The impact of aging on mitochondrial function and biogenesis pathways in skeletal muscle of sedentary high- and low-functioning elderly individuals

(2012) Anna-Maria Joseph et al.   AGING CELL

Contractile activity-induced mitochondrial biogenesis and mTORC1

(2012) Heather N. Carter et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Adaptive plasticity of autophagic proteins to denervation in aging skeletal muscle

(2012) Michael F. O'Leary et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Elevated energy coupling and aerobic capacity improves exercise performance in endurance-trained elderly subjects

(2012) Kevin E. Conley et al.   EXPERIMENTAL PHYSIOLOGY

Voltage-dependent Anion Channels (VDACs) Recruit Parkin to Defective Mitochondria to Promote Mitochondrial Autophagy

(2012) Yu Sun et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Exercise-induced BCL2-regulated autophagy is required for muscle glucose homeostasis

(2012) Congcong He et al.   NATURE

A comprehensive assessment of mitochondrial protein synthesis and cellular proliferation with age and caloric restriction

(2011) Benjamin F. Miller et al.   AGING CELL

Alterations in intrinsic mitochondrial function with aging are fiber type-specific and do not explain differential atrophy between muscles

(2011) Martin Picard et al.   AGING CELL

Physical exercise stimulates autophagy in normal skeletal muscles but is detrimental for collagen VI-deficient muscles

(2011) Paolo Grumati et al.   Autophagy

Autophagy and Aging

(2011) David C. Rubinsztein et al.   CELL

Sarcopenia Accelerates at Advanced Ages in Fisher 344xBrown Norway Rats

(2011) E. B. Lushaj et al.   JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES

Quantitation of "autophagic flux" in mature skeletal muscle

(2010) Jeong-Sun Ju et al.   Autophagy

Autophagy regulation by p53

(2010) Maria Chiara Maiuri et al.   CURRENT OPINION IN CELL BIOLOGY

Mitofusin 1 and mitofusin 2 are ubiquitinated in a PINK1/parkin-dependent manner upon induction of mitophagy

(2010) Matthew E. Gegg et al.   HUMAN MOLECULAR GENETICS

PINK1 stabilized by mitochondrial depolarization recruits Parkin to damaged mitochondria and activates latent Parkin for mitophagy

(2010) Noriyuki Matsuda et al.   JOURNAL OF CELL BIOLOGY

Diminished contraction-induced intracellular signaling towards mitochondrial biogenesis in aged skeletal muscle

(2009) Vladimir Ljubicic et al.   AGING CELL

The role of PGC-1α on mitochondrial function and apoptotic susceptibility in muscle

(2009) Peter J. Adhihetty et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Mitochondrial Turnover and Aging of Long-Lived Postmitotic Cells: The Mitochondrial–Lysosomal Axis Theory of Aging

(2009) Alexei Terman et al.   ANTIOXIDANTS & REDOX SIGNALING

Autophagy Is Required to Maintain Muscle Mass

(2009) Eva Masiero et al.   Cell Metabolism

Skeletal muscle autophagy and apoptosis during aging: Effects of calorie restriction and life-long exercise

(2009) Stephanie Eva Wohlgemuth et al.   EXPERIMENTAL GERONTOLOGY

Role of p53 in mitochondrial biogenesis and apoptosis in skeletal muscle

(2008) Ayesha Saleem et al.   PHYSIOLOGICAL GENOMICS

Mitochondrial function and apoptotic susceptibility in aging skeletal muscle

(2007) Béatrice Chabi et al.   AGING CELL