PGC-1α modulates denervation-induced mitophagy in skeletal muscle

PARK2/Parkin-mediated mitochondrial clearance contributes to proteasome activation during slow-twitch muscle atrophy via NFE2L1 nuclear translocation

(2014) Norihiko Furuya et al.   Autophagy

Molecular insights into mitochondrial dysfunction in cancer-related muscle wasting

(2014) Diana Antunes et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Autophagy-regulating TP53INP2 mediates muscle wasting and is repressed in diabetes

(2014) David Sala et al.   JOURNAL OF CLINICAL INVESTIGATION

Sirtuin 1-mediated Effects of Exercise and Resveratrol on Mitochondrial Biogenesis

(2013) Keir J. Menzies et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

GCN5-like Protein 1 (GCN5L1) Controls Mitochondrial Content through Coordinated Regulation of Mitochondrial Biogenesis and Mitophagy

(2013) Iain Scott et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Skeletal muscle, autophagy, and physical activity: the ménage à trois of metabolic regulation in health and disease

(2013) Anna Vainshtein et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

TFEB controls cellular lipid metabolism through a starvation-induced autoregulatory loop

(2013) Carmine Settembre et al.   NATURE CELL BIOLOGY

Denervation-induced mitochondrial dysfunction and autophagy in skeletal muscle of apoptosis-deficient animals

(2012) Michael F. N. O′Leary et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Adaptive plasticity of autophagic proteins to denervation in aging skeletal muscle

(2012) Michael F. O'Leary et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

RETRACTED: The Ubiquitin Ligase Mul1 Induces Mitophagy in Skeletal Muscle in Response to Muscle-Wasting Stimuli

(2012) Sudarsanareddy Lokireddy et al.   Cell Metabolism

Mitochondria Sentencing About Cellular Life and Death: A Matter of Oxidative Stress

(2012) Nadezda Apostolova et al.   CURRENT PHARMACEUTICAL DESIGN

Proteasome-dependent Activation of Mammalian Target of Rapamycin Complex 1 (mTORC1) Is Essential for Autophagy Suppression and Muscle Remodeling Following Denervation

(2012) Pham Nguyen Quy et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Exercise-induced BCL2-regulated autophagy is required for muscle glucose homeostasis

(2012) Congcong He et al.   NATURE

PGC-1  Rescues Huntington's Disease Proteotoxicity by Preventing Oxidative Stress and Promoting TFEB Function

(2012) T. Tsunemi et al.   Science Translational Medicine

PGC-1α Promotes Nitric Oxide Antioxidant Defenses and Inhibits FOXO Signaling Against Cardiac Cachexia in Mice

(2011) Tuoyu Geng et al.   AMERICAN JOURNAL OF PATHOLOGY

Impact of PGC-1α on the topology and rate of superoxide production by the mitochondrial electron transport chain

(2011) Shane Austin et al.   FREE RADICAL BIOLOGY AND MEDICINE

Effects of endurance training on apoptotic susceptibility in striated muscle

(2011) Anna Vainshtein et al.   JOURNAL OF APPLIED PHYSIOLOGY

TFEB Links Autophagy to Lysosomal Biogenesis

(2011) C. Settembre et al.   SCIENCE

Quantitation of "autophagic flux" in mature skeletal muscle

(2010) Jeong-Sun Ju et al.   Autophagy

Metabolic control of mitochondrial biogenesis through the PGC-1 family regulatory network

(2010) Richard C. Scarpulla   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Autophagy is defective in collagen VI muscular dystrophies and its reactivation rescues myofiber degeneration

(2010) Paolo Grumati et al.   NATURE MEDICINE

Fiber Type Conversion by PGC-1α Activates Lysosomal and Autophagosomal Biogenesis in Both Unaffected and Pompe Skeletal Muscle

(2010) Shoichi Takikita et al.   PLoS One

The role of PGC-1α on mitochondrial function and apoptotic susceptibility in muscle

(2009) Peter J. Adhihetty et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Denervation-induced oxidative stress and autophagy signaling in muscle

(2009) Michael F.N. O’Leary et al.   Autophagy

Autophagy Is Required to Maintain Muscle Mass

(2009) Eva Masiero et al.   Cell Metabolism

Age-associated mitochondrial dysfunction in skeletal muscle: Contributing factors and suggestions for long-term interventions

(2009) Julianna H. Huang et al.   IUBMB LIFE

PGC-1α activation as a therapeutic approach in mitochondrial disease

(2009) Tina Wenz   IUBMB LIFE

Hypoxia-Induced Autophagy Is Mediated through Hypoxia-Inducible Factor Induction of BNIP3 and BNIP3L via Their BH3 Domains

(2009) G. Bellot et al.   MOLECULAR AND CELLULAR BIOLOGY

Increased muscle PGC-1  expression protects from sarcopenia and metabolic disease during aging

(2009) T. Wenz et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

PGC-1  is coupled to HIF-1 -dependent gene expression by increasing mitochondrial oxygen consumption in skeletal muscle cells

(2009) K. A. O'Hagan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Fission and selective fusion govern mitochondrial segregation and elimination by autophagy

(2008) Gilad Twig et al.   EMBO JOURNAL

Muscle-specific expression of PPARγ coactivator-1α improves exercise performance and increases peak oxygen uptake

(2008) Jennifer A. Calvo et al.   JOURNAL OF APPLIED PHYSIOLOGY