Ablation of caspase-1 protects against TBI-induced pyroptosis in vitro and in vivo

Inflammasome: Its role in traumatic brain and spinal cord injury

(2018) Keywan Mortezaee et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Anti-inflammatory and immunomodulatory mechanisms of atorvastatin in a murine model of traumatic brain injury

(2017) Xin Xu et al.   Journal of Neuroinflammation

Regulation of Mitochondrial Function and Glutamatergic System Are the Target of Guanosine Effect in Traumatic Brain Injury

(2017) Fernando Dobrachinski et al.   JOURNAL OF NEUROTRAUMA

Melatonin alleviates inflammasome-induced pyroptosis through inhibiting NF-κB/GSDMD signal in mice adipose tissue

(2017) Zhenjiang Liu et al.   JOURNAL OF PINEAL RESEARCH

Research Frontiers in Traumatic Brain Injury

(2017) Andrew J. Gardner et al.   Physical Medicine and Rehabilitation Clinics of North America

Gasdermins: Effectors of Pyroptosis

(2017) Stephen B. Kovacs et al.   TRENDS IN CELL BIOLOGY

Multimodal Imaging of Neurometabolic Pathology due to Traumatic Brain Injury

(2017) John Darrell Van Horn et al.   TRENDS IN NEUROSCIENCES

The P2X7 Receptor Primes IL-1β and the NLRP3 Inflammasome in Astrocytes Exposed to Mechanical Strain

(2017) Farraj Albalawi et al.   Frontiers in Cellular Neuroscience

Rehabilitation Treatment and Progress of Traumatic Brain Injury Dysfunction

(2017) Baoqi Dang et al.   NEURAL PLASTICITY

Lack of the Nlrp3 Inflammasome Improves Mice Recovery Following Traumatic Brain Injury

(2017) Natasha Irrera et al.   Frontiers in Pharmacology

Monitoring the Neuroinflammatory Response Following Acute Brain Injury

(2017) Eric Peter Thelin et al.   Frontiers in Neurology

Roles of Caspases in Necrotic Cell Death

(2016) Junying Yuan et al.   CELL

MiR-155 is Involved in Renal Ischemia-Reperfusion Injury via Direct Targeting of FoxO3a and Regulating Renal Tubular Cell Pyroptosis

(2016) Haoyu Wu et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

The cell biology of inflammasomes: Mechanisms of inflammasome activation and regulation

(2016) Deepika Sharma et al.   JOURNAL OF CELL BIOLOGY

Caspase-1 as a multifunctional inflammatory mediator: noncytokine maturation roles

(2016) Qian Sun et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Neurogenic inflammation after traumatic brain injury and its potentiation of classical inflammation

(2016) Frances Corrigan et al.   Journal of Neuroinflammation

Pore-forming activity and structural autoinhibition of the gasdermin family

(2016) Jingjin Ding et al.   NATURE

Inflammasome-activated gasdermin D causes pyroptosis by forming membrane pores

(2016) Xing Liu et al.   NATURE

DPP8 and DPP9 inhibition induces pro-caspase-1-dependent monocyte and macrophage pyroptosis

(2016) Marian C Okondo et al.   Nature Chemical Biology

Inflammatory neuroprotection following traumatic brain injury

(2016) M. V. Russo et al.   SCIENCE

Interferon Regulatory Factor-1 Mediates Alveolar Macrophage Pyroptosis During LPS-Induced Acute Lung Injury in Mice

(2016) Dongdong Wu et al.   SHOCK

Gossypol induces pyroptosis in mouse macrophages via a non-canonical inflammasome pathway

(2016) Qiu-Ru Lin et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Impact of mechanical stretch on the cell behaviors of bone and surrounding tissues

(2016) Hye-Sun Yu et al.   Journal of Tissue Engineering

Rhein and rhubarb similarly protect the blood-brain barrier after experimental traumatic brain injury via gp91phox subunit of NADPH oxidase/ROS/ERK/MMP-9 signaling pathway

(2016) Yang Wang et al.   Scientific Reports

Traumatic Brain Injury and Mitochondrial Dysfunction

(2015) John B. Hiebert et al.   AMERICAN JOURNAL OF THE MEDICAL SCIENCES

Downregulation of STIM2 improves neuronal survival after traumatic brain injury by alleviating calcium overload and mitochondrial dysfunction

(2015) Wei Rao et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Neuronal NLRP1 inflammasome activation of Caspase-1 coordinately regulates inflammatory interleukin-1-beta production and axonal degeneration-associated Caspase-6 activation

(2015) V Kaushal et al.   CELL DEATH AND DIFFERENTIATION

Caspase-11 Requires the Pannexin-1 Channel and the Purinergic P2X7 Pore to Mediate Pyroptosis and Endotoxic Shock

(2015) Dahai Yang et al.   IMMUNITY

Traumatic Brain Injury and the Neuronal Microenvironment: A Potential Role for Neuropathological Mechanotransduction

(2015) Matthew A. Hemphill et al.   NEURON

Pyroptotic Neuronal Cell Death Mediated by the AIM2 Inflammasome

(2014) Stephanie E Adamczak et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Inflammasomes

(2014) M. R. de Zoete et al.   Cold Spring Harbor Perspectives in Biology

Candida albicans Triggers NLRP3-Mediated Pyroptosis in Macrophages

(2013) Melanie Wellington et al.   EUKARYOTIC CELL

Alarmin HNP-1 promotes pyroptosis and IL-1β release through different roles of NLRP3 inflammasome via P2X7 in LPS-primed macrophages

(2013) Qixing Chen et al.   Innate Immunity

Changing patterns in the epidemiology of traumatic brain injury

(2013) Bob Roozenbeek et al.   Nature Reviews Neurology

Biomarkers of mild traumatic brain injury in cerebrospinal fluid and blood

(2013) Henrik Zetterberg et al.   Nature Reviews Neurology

Expression of the NLRP3 Inflammasome in Cerebral Cortex After Traumatic Brain Injury in a Rat Model

(2013) Huan-Dong Liu et al.   NEUROCHEMICAL RESEARCH

Non-canonical inflammasome activation targets caspase-11

(2011) Nobuhiko Kayagaki et al.   NATURE

The inflammasome promotes adverse cardiac remodeling following acute myocardial infarction in the mouse

(2011) E. Mezzaroma et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Cytokine Response to Human Traumatic Brain Injury: Temporal Profiles and Evidence for Cerebral Parenchymal Production

(2010) Adel Helmy et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Exploring New Routes for Neuroprotective Drug Development in Traumatic Brain Injury

(2010) T. Janowitz et al.   Science Translational Medicine

The Challenges of Assessing the Incidence of Inflicted Traumatic Brain Injury

(2008) Desmond K. Runyan   AMERICAN JOURNAL OF PREVENTIVE MEDICINE

Inhibition of the Inflammasome Complex Reduces the Inflammatory Response after Thromboembolic Stroke in Mice

(2008) Denise P Abulafia et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM