Alarmin HNP-1 promotes pyroptosis and IL-1β release through different roles of NLRP3 inflammasome via P2X7 in LPS-primed macrophages

Analysis of Sputum Markers in the Evaluation of Lung Inflammation and Functional Impairment in Symptomatic Smokers and COPD Patients

(2013) Gregorino Paone et al.   DISEASE MARKERS

Inflammasomes in health and disease

(2012) Till Strowig et al.   NATURE

The Inflammasome NLRs in Immunity, Inflammation, and Associated Diseases

(2011) Beckley K. Davis et al.   Annual Review of Immunology

Nuclear factor-κB mediated lipopolysaccharide-induced mRNA expression of hepcidin in human peripheral blood leukocytes

(2011) ShuiJing Wu et al.   Innate Immunity

High-mobility group nucleosome-binding protein 1 acts as an alarmin and is critical for lipopolysaccharide-induced immune responses

(2011) De Yang et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Coordinated Host Responses during Pyroptosis: Caspase-1-Dependent Lysosome Exocytosis and Inflammatory Cytokine Maturation

(2011) T. Bergsbaken et al.   JOURNAL OF IMMUNOLOGY

Non-canonical inflammasome activation targets caspase-11

(2011) Nobuhiko Kayagaki et al.   NATURE

Neutrophil α-Defensins Cause Lung Injury by Disrupting the Capillary–Epithelial Barrier

(2010) Khalil Bdeir et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Increased Genomic Copy Number of DEFA1/DEFA3 Is Associated with Susceptibility to Severe Sepsis in Chinese Han Population

(2010) QiXing Chen et al.   ANESTHESIOLOGY

Granulysin activates antigen-presenting cells through TLR4 and acts as an immune alarmin

(2010) P. Tewary et al.   BLOOD

The Inflammasomes

(2010) Kate Schroder et al.   CELL

Specific Binding and Chemotactic Activity of mBD4 and Its Functional Orthologue hBD2 to CCR6-expressing Cells

(2010) Johann Röhrl et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Trp-26 Imparts Functional Versatility to Human α-Defensin HNP1

(2010) Gang Wei et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Human  -Defensin 2 and 3 and Their Mouse Orthologs Induce Chemotaxis through Interaction with CCR2

(2010) J. Rohrl et al.   JOURNAL OF IMMUNOLOGY

IL-1β Processing in Host Defense: Beyond the Inflammasomes

(2010) Mihai G. Netea et al.   PLoS Pathogens

Human Neutrophil Peptides and Phagocytic Deficiency in Bronchiectatic Lungs

(2009) Stefanos Voglis et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

T cells dampen innate immune responses through inhibition of NLRP1 and NLRP3 inflammasomes

(2009) Greta Guarda et al.   NATURE

Thioredoxin-interacting protein links oxidative stress to inflammasome activation

(2009) Rongbin Zhou et al.   NATURE IMMUNOLOGY

Pyroptosis: host cell death and inflammation

(2009) Tessa Bergsbaken et al.   NATURE REVIEWS MICROBIOLOGY

Alarmins link neutrophils and dendritic cells

(2009) De Yang et al.   TRENDS IN IMMUNOLOGY

AMPed up immunity: how antimicrobial peptides have multiple roles in immune defense

(2009) Yuping Lai et al.   TRENDS IN IMMUNOLOGY

Antimicrobial peptides in lung transplant recipients with bronchiolitis obliterans syndrome

(2008) R. L. Anderson et al.   EUROPEAN RESPIRATORY JOURNAL

Eosinophil-derived neurotoxin acts as an alarmin to activate the TLR2–MyD88 signal pathway in dendritic cells and enhances Th2 immune responses

(2008) De Yang et al.   JOURNAL OF EXPERIMENTAL MEDICINE